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Page 1
Estrogen and cardiovascular disease.
Gersh F, O'Keefe JH, Elagizi A, Lavie CJ, Laukkanen JA. Gersh F, et al. Prog Cardiovasc Dis. 2024 May-Jun;84:60-67. doi: 10.1016/j.pcad.2024.01.015. Epub 2024 Jan 24. Prog Cardiovasc Dis. 2024. PMID: 38272338 Review.
In contrast, accelerated development of CV disease (CVD) occurs in the absence of ovarian produced E2 and P4. Hormone replacement therapy (HRT) with E2 and P4 has been shown to cause no harm to younger menopausal women. ...With the current expanded understanding of …
In contrast, accelerated development of CV disease (CVD) occurs in the absence of ovarian produced E2 and P4. Hormone replacement …
Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association.
El Khoudary SR, Aggarwal B, Beckie TM, Hodis HN, Johnson AE, Langer RD, Limacher MC, Manson JE, Stefanick ML, Allison MA; American Heart Association Prevention Science Committee of the Council on Epidemiology and Prevention; and Council on Cardiovascular and Stroke Nursing. El Khoudary SR, et al. Circulation. 2020 Dec 22;142(25):e506-e532. doi: 10.1161/CIR.0000000000000912. Epub 2020 Nov 30. Circulation. 2020. PMID: 33251828 Free article. Review.
Cardiovascular disease (CVD) is the leading cause of death in women, who have a notable increase in the risk for this disease after menopause and typically develop coronary heart disease several years later than men. This observation led to the hypothesis that the m …
Cardiovascular disease (CVD) is the leading cause of death in women, who have a notable increase in the risk for this disease after m …
Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol.
Hodis HN, Mack WJ, Henderson VW, Shoupe D, Budoff MJ, Hwang-Levine J, Li Y, Feng M, Dustin L, Kono N, Stanczyk FZ, Selzer RH, Azen SP; ELITE Research Group. Hodis HN, et al. N Engl J Med. 2016 Mar 31;374(13):1221-31. doi: 10.1056/NEJMoa1505241. N Engl J Med. 2016. PMID: 27028912 Free PMC article. Clinical Trial.
BACKGROUND: Data suggest that estrogen-containing hormone therapy is associated with beneficial effects with regard to cardiovascular disease when the therapy is initiated temporally close to menopause but not when it is initiated later. However, the …
BACKGROUND: Data suggest that estrogen-containing hormone therapy is associated with beneficial effects with regard to card …
Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause.
Lobo RA, Pickar JH, Stevenson JC, Mack WJ, Hodis HN. Lobo RA, et al. Atherosclerosis. 2016 Nov;254:282-290. doi: 10.1016/j.atherosclerosis.2016.10.005. Epub 2016 Oct 6. Atherosclerosis. 2016. PMID: 27745704 Free article. Review.
In the late 1980s, several observational studies and meta-analyses suggested that hormone replacement therapy (HRT) was beneficial for prevention of osteoporosis, coronary heart disease, dementia and decreased all-cause mortality. ...It has also been reported that m …
In the late 1980s, several observational studies and meta-analyses suggested that hormone replacement therapy (HRT) was benefi …
Timing of hormone therapy and its association with cardiovascular risk and metabolic parameters in 4-vinylcyclohexene diepoxide-induced primary ovarian insufficiency mouse model.
Lee HJ, Park MJ, Heo JD, Joo BS, Joo JK. Lee HJ, et al. Gynecol Endocrinol. 2023 Aug 12;39(1):2247094. doi: 10.1080/09513590.2023.2247094. Gynecol Endocrinol. 2023. PMID: 37599578 Free article.
OBJECTIVE: To evaluate the effects of various initiation time points and durations of hormone therapy (HT) on cardiovascular and metabolic parameters of premenarche, primary ovarian insufficiency (POI) mouse model, induced by 4-vinylcyclohexene diepoxide. ... …
OBJECTIVE: To evaluate the effects of various initiation time points and durations of hormone therapy (HT) on cardiovascula …
The Timing Hypothesis: Hormone Therapy for Treating Symptomatic Women During Menopause and Its Relationship to Cardiovascular Disease.
Mehta JM, Chester RC, Kling JM. Mehta JM, et al. J Womens Health (Larchmt). 2019 May;28(5):705-711. doi: 10.1089/jwh.2018.7201. Epub 2018 Nov 28. J Womens Health (Larchmt). 2019. PMID: 30484736
The timing hypothesis, which posits that the cardiovascular effects of HT depend on the timing of initiation of HT in relation to menopause, has helped shape our understanding of the cardiovascular outcomes related to HT. Based on results from f …
The timing hypothesis, which posits that the cardiovascular effects of HT depend on the timing of initiation of …
Timing hypothesis for postmenopausal hormone therapy: its origin, current status, and future.
Clarkson TB, Meléndez GC, Appt SE. Clarkson TB, et al. Menopause. 2013 Mar;20(3):342-53. doi: 10.1097/GME.0b013e3182843aad. Menopause. 2013. PMID: 23435033 Review.
OBJECTIVE: This work aims to review preclinical/clinical cardiovascular studies that led to randomized trials of the risks and benefits of postmenopausal hormone therapy (HT), the pathobiological basis for the timing hypothesis, and subset analy …
OBJECTIVE: This work aims to review preclinical/clinical cardiovascular studies that led to randomized trials of the risks and benefi …
The Kronos Early Estrogen Prevention Study (KEEPS): what have we learned?
Miller VM, Naftolin F, Asthana S, Black DM, Brinton EA, Budoff MJ, Cedars MI, Dowling NM, Gleason CE, Hodis HN, Jayachandran M, Kantarci K, Lobo RA, Manson JE, Pal L, Santoro NF, Taylor HS, Harman SM. Miller VM, et al. Menopause. 2019 Sep;26(9):1071-1084. doi: 10.1097/GME.0000000000001326. Menopause. 2019. PMID: 31453973 Free PMC article. Review.
OBJECTIVE: The Kronos Early Estrogen Prevention Study (KEEPS) was designed to address gaps in understanding the effects of timely menopausal hormone treatments (HT) on cardiovascular health and other effects of menopause after the premature termination of the …
OBJECTIVE: The Kronos Early Estrogen Prevention Study (KEEPS) was designed to address gaps in understanding the effects of timely men …
The timing hypothesis: Do coronary risks of menopausal hormone therapy vary by age or time since menopause onset?
Bassuk SS, Manson JE. Bassuk SS, et al. Metabolism. 2016 May;65(5):794-803. doi: 10.1016/j.metabol.2016.01.004. Epub 2016 Jan 12. Metabolism. 2016. PMID: 27085786 Free PMC article. Review.
The Women's Health Initiative (WHI), a landmark randomized trial of menopausal hormone therapy (HT) for prevention of chronic disease in postmenopausal women aged 50-79, established that such therapy neither prevents coronary heart disease (CHD) nor yields a …
The Women's Health Initiative (WHI), a landmark randomized trial of menopausal hormone therapy (HT) for prevention of chronic …
The effects of estrogen and hormone replacement therapy on cardiovascular systems.
Hashemzadeh M, Romo R, Arreguin JM, Movahed MR. Hashemzadeh M, et al. Future Cardiol. 2021 Mar;17(2):347-353. doi: 10.2217/fca-2020-0054. Epub 2020 Nov 16. Future Cardiol. 2021. PMID: 33191784 Review.
Postmenopausal women have an increased risk of cardiovascular disease, which is believed to correlate with lower estrogen level. There are conflicting data regarding hormone replacement therapy (HRT) based on the timing of this therapy. ...There …
Postmenopausal women have an increased risk of cardiovascular disease, which is believed to correlate with lower estrogen level. Ther …
67 results