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Measurement properties of grimace scales for pain assessment in non-human mammals: a systematic review.
Evangelista MC, Monteiro BP, Steagall PV. Evangelista MC, et al. Pain. 2021 Sep 9. doi: 10.1097/j.pain.0000000000002474. Online ahead of print. Pain. 2021. PMID: 34510132
Facial expressions of pain have been identified in several animal species. The aim of this systematic review was to provide evidence on the measurement properties of grimace scales for pain assessment. ...The Mouse, Rat, Horse and Feline Grimace Scales exhibi …
Facial expressions of pain have been identified in several animal species. The aim of this systematic review was to provide evidence …
Split Cord Malformation in a Thoroughbred Horse.
De Jonge B, Dufourni A, Oosterlinck M, Chiers K. De Jonge B, et al. J Comp Pathol. 2021 Aug;187:68-74. doi: 10.1016/j.jcpa.2021.07.003. Epub 2021 Aug 12. J Comp Pathol. 2021. PMID: 34503656
We report a 9-year-old Thoroughbred gelding that had sudden onset lameness of the right forelimb with episodes of lateral decubitus and generalized pain after completion of a normal training session. The clinical signs subsequently became less pronounced with only mild rig …
We report a 9-year-old Thoroughbred gelding that had sudden onset lameness of the right forelimb with episodes of lateral decubitus and gene …
Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development.
McReynolds CB, Yang J, Guedes A, Morisseau C, Garcia R, Knych H, Tearney C, Hamamoto B, Hwang SH, Wagner K, Hammock BD. McReynolds CB, et al. Molecules. 2021 Aug 19;26(16):5034. doi: 10.3390/molecules26165034. Molecules. 2021. PMID: 34443621 Free PMC article.
The purpose of this paper was to assess the pharmacokinetics after oral and intravenous dosing in domesticated animal species (dogs, cats, and horses) of a novel soluble epoxide hydrolase inhibitor, EC1728, being developed for the treatment of pain in animals. ...Ad …
The purpose of this paper was to assess the pharmacokinetics after oral and intravenous dosing in domesticated animal species (dogs, cats, a …
Targeting Soluble Epoxide Hydrolase and Cyclooxygenases Enhance Joint Pain Control, Stimulate Collagen Synthesis, and Protect Chondrocytes From Cytokine-Induced Apoptosis.
Tucker L, Trumble TN, Groschen D, Dobbs E, Baldo CF, Wendt-Hornickle E, Guedes AGP. Tucker L, et al. Front Vet Sci. 2021 Aug 5;8:685824. doi: 10.3389/fvets.2021.685824. eCollection 2021. Front Vet Sci. 2021. PMID: 34422942 Free PMC article.
Results: Combined COX and sEH inhibition produced significantly better control of joint pain, prostanoid responses, and collagen synthesis-degradation balance compared to each compound separately. When administered separately, pain control was superior with COX vs. …
Results: Combined COX and sEH inhibition produced significantly better control of joint pain, prostanoid responses, and collagen synt …
Cellular distribution of cannabinoid-related receptors TRPV1, PPAR-gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia.
Galiazzo G, De Silva M, Giancola F, Rinnovati R, Peli A, Chiocchetti R. Galiazzo G, et al. Equine Vet J. 2021 Aug 21. doi: 10.1111/evj.13499. Online ahead of print. Equine Vet J. 2021. PMID: 34418142
BACKGROUND: The activation of cannabinoid and cannabinoid-related receptors by endogenous, plant-derived or synthetic cannabinoids may exert beneficial effects on pain perception. Of the cannabinoids contained in Cannabis sativa, cannabidiol (CBD) does not produce psychotr …
BACKGROUND: The activation of cannabinoid and cannabinoid-related receptors by endogenous, plant-derived or synthetic cannabinoids may exert …
Repeated intra-articular administration of equine allogeneic peripheral blood-derived mesenchymal stem cells does not induce a cellular and humoral immune response in horses.
Van Hecke L, Magri C, Duchateau L, Beerts C, Geburek F, Suls M, Da Dalt L, Patruno M, Saunders J, Broeckx SY, Depuydt E, Spaas JH. Van Hecke L, et al. Vet Immunol Immunopathol. 2021 Sep;239:110306. doi: 10.1016/j.vetimm.2021.110306. Epub 2021 Aug 2. Vet Immunol Immunopathol. 2021. PMID: 34365135 Free article.
Stem cells from 2 donor horses were used. Horses were clinically evaluated for joint effusion, presence of pain to palpation and skin surface temperature at the local injection site, joint range of motion, occurrence of adverse events and the presence of ecto …
Stem cells from 2 donor horses were used. Horses were clinically evaluated for joint effusion, presence of pain to palp …
Equine grass sickness in italy: a case series study.
Fulvio L, Jacopo C, Teresa MM, Marilena B, Alice B, Rodolfo G. Fulvio L, et al. BMC Vet Res. 2021 Aug 6;17(1):264. doi: 10.1186/s12917-021-02966-y. BMC Vet Res. 2021. PMID: 34362361 Free PMC article.
According to clinical presentation, acute, subacute and chornic syndromes can be observed, with various sympthoms including dullness, anorexia, dysphagia, drooling of saliva, tachycardia, ptosis, patchy sweating and muscle fasciculations. In horses affected by acute forms, …
According to clinical presentation, acute, subacute and chornic syndromes can be observed, with various sympthoms including dullness, anorex …
Synovial Concentration of Trimethoprim-Sulphadiazine Following Regional Limb Perfusion in Standing Horses.
Gustafsson K, Tatz AJ, Dahan R, Abu Ahmad W, Britzi M, Sutton GA, Kelmer G. Gustafsson K, et al. Animals (Basel). 2021 Jul 13;11(7):2085. doi: 10.3390/ani11072085. Animals (Basel). 2021. PMID: 34359213 Free PMC article.
Severe vasculitis and pain shortly after IVRLP, lasting up to one week post-injection, occurred in five out of 10 horses. In conclusion, IVRLP with trimethoprim-sulphadiazine cannot be recommended due to the low concentrations of synovial fluid over time and the fre …
Severe vasculitis and pain shortly after IVRLP, lasting up to one week post-injection, occurred in five out of 10 horses. In c …
A critical evaluation for validation of composite and unidimensional postoperative pain scales in horses.
Barreto da Rocha P, Driessen B, McDonnell SM, Hopster K, Zarucco L, Gozalo-Marcilla M, Hopster-Iversen C, Esteves Trindade PH, Gonzaga da Rocha TK, Taffarel MO, Alonso BB, Schauvliege S, Luna SPL. Barreto da Rocha P, et al. PLoS One. 2021 Aug 5;16(8):e0255618. doi: 10.1371/journal.pone.0255618. eCollection 2021. PLoS One. 2021. PMID: 34352001 Free PMC article.
Proper pain therapy requires adequate pain assessment. This study evaluated the reliability and validity of the Unesp-Botucatu horse acute pain scale (UHAPS), the Orthopedic Composite Pain Scale (CPS) and unidimensional scales in horses a …
Proper pain therapy requires adequate pain assessment. This study evaluated the reliability and validity of the Unesp-Botucatu …
Sparing the gut: COX-2 inhibitors herald a new era for treatment of horses with surgical colic.
Ziegler AL, Blikslager AT. Ziegler AL, et al. Equine Vet Educ. 2020 Nov;32(11):611-616. doi: 10.1111/eve.13189. Epub 2019 Oct 4. Equine Vet Educ. 2020. PMID: 34305336 Free PMC article.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to manage a wide variety of conditions in horses, including management of colic. Flunixin meglumine is by far the most commonly used drug in the control of colic pain and inflammation and has become a g …
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to manage a wide variety of conditions in horses, including managemen …
Comparison Between Ultrasonographic and Standing Magnetic Resonance Imaging Findings in the Podotrochlear Apparatus of Horses With Foot Pain.
Evrard L, Joostens Z, Vandersmissen M, Audigié F, Busoni V. Evrard L, et al. Front Vet Sci. 2021 Jul 5;8:675180. doi: 10.3389/fvets.2021.675180. eCollection 2021. Front Vet Sci. 2021. PMID: 34291100 Free PMC article.
This prospective study aimed to blindly compare the ultrasonographic and standing magnetic resonance imaging (sMRI) findings in deep digital flexor tendon (DDFT), navicular bone, and navicular bursa in horses with foot pain, positive digital analgesia, and without d …
This prospective study aimed to blindly compare the ultrasonographic and standing magnetic resonance imaging (sMRI) findings in deep digital …
Transdermal Application of Anesthetic Preparations Is Effective in Increasing Mechanical Nociceptive Threshold at Perineural Injection Sites in Horses.
Pagliara E, Nicolo A, Rossi C, Cammaresi C, Donadio G, Bertuglia A. Pagliara E, et al. J Equine Vet Sci. 2021 Aug;103:103689. doi: 10.1016/j.jevs.2021.103689. Epub 2021 Jun 16. J Equine Vet Sci. 2021. PMID: 34281641
Perineural anaesthesia is an essential part of lameness investigation in horses. Painful reactions to injections imply a high risk of accidents for veterinarians. To evaluate the efficacy of two topical anaesthetic creams on desensitization of the skin at two perineural in …
Perineural anaesthesia is an essential part of lameness investigation in horses. Painful reactions to injections imply a high risk of …
Emergency Management for Donkeys and Mules.
Archer DC, Sullivan RJE, Rickards K. Archer DC, et al. Vet Clin North Am Equine Pract. 2021 Aug;37(2):495-513. doi: 10.1016/j.cveq.2021.04.013. Vet Clin North Am Equine Pract. 2021. PMID: 34243882 Review.
This article provides an overview of initial assessment and management of common emergency presentations in donkeys and mules. The principles are similar to those in horses (and ponies), but clinicians must be aware of differences in recognition of signs of pain/dis …
This article provides an overview of initial assessment and management of common emergency presentations in donkeys and mules. The principle …
Objective Assessment of Chronic Pain in Horses Using the Horse Chronic Pain Scale (HCPS): A Scale-Construction Study.
van Loon JPAM, Macri L. van Loon JPAM, et al. Animals (Basel). 2021 Jun 18;11(6):1826. doi: 10.3390/ani11061826. Animals (Basel). 2021. PMID: 34207290 Free PMC article.
The aim of this study was to develop a pain scale for the assessment of chronic pain in horses (Horse Chronic Pain Scale; HCPS), which is based on behavioural and facial expressions. ...In conclusion, we tested a composite pain scale for …
The aim of this study was to develop a pain scale for the assessment of chronic pain in horses (Horse Chronic …
Application of the Ridden Horse Pain Ethogram to Horses Competing at the Hickstead-Rotterdam Grand Prix Challenge and the British Dressage Grand Prix National Championship 2020 and Comparison with World Cup Grand Prix Competitions.
Dyson S, Pollard D. Dyson S, et al. Animals (Basel). 2021 Jun 18;11(6):1820. doi: 10.3390/ani11061820. Animals (Basel). 2021. PMID: 34207251 Free PMC article.
The Ridden Horse Pain Ethogram (RHpE) comprising 24 behaviours was developed to facilitate the identification of musculoskeletal discomfort, with scores of 8/24 indicating the presence of pain. ...The median RHpE scores were four (IQR 3-6; range 0-8) and six …
The Ridden Horse Pain Ethogram (RHpE) comprising 24 behaviours was developed to facilitate the identification of musculoskelet …
Towards Machine Recognition of Facial Expressions of Pain in Horses.
Andersen PH, Broomé S, Rashid M, Lundblad J, Ask K, Li Z, Hernlund E, Rhodin M, Kjellström H. Andersen PH, et al. Animals (Basel). 2021 Jun 1;11(6):1643. doi: 10.3390/ani11061643. Animals (Basel). 2021. PMID: 34206077 Free PMC article. Review.
However, the application of such methods to horses has proven difficult. Major barriers are the lack of sufficiently large, annotated databases for horses and difficulties in obtaining correct classifications of pain because horses are non-verbal. ...O …
However, the application of such methods to horses has proven difficult. Major barriers are the lack of sufficiently large, annotated …
Proximal Perineural Femoral Nerve Injection in Pigs Using an Ultrasound-Guided Lateral Subiliac Approach-A Cadaveric Study.
Trujanovic R, Otero PE, Marhofer P, Auer U, Kau S. Trujanovic R, et al. Animals (Basel). 2021 Jun 12;11(6):1759. doi: 10.3390/ani11061759. Animals (Basel). 2021. PMID: 34204599 Free PMC article.
Desensitizing the femoral nerve (FN) improves pain control in several species undergoing pelvic limb surgeries. ...
Desensitizing the femoral nerve (FN) improves pain control in several species undergoing pelvic limb surgeries. ...
Attitudes of the Equestrian Public towards Equine End-of-Life Decisions.
Bell C, Rogers S. Bell C, et al. Animals (Basel). 2021 Jun 14;11(6):1776. doi: 10.3390/ani11061776. Animals (Basel). 2021. PMID: 34198636 Free PMC article.
A key welfare concern for the equine population in the U.K. has been identified as delayed death, leading to prolonged suffering of horses. Reasons why some horse owners fail to have their horses euthanised include financial cost, emotional attachment, peer p …
A key welfare concern for the equine population in the U.K. has been identified as delayed death, leading to prolonged suffering of horse
Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial.
Marian IR, Goff M, Williams JAE, Gulati M, Chester-Jones M, Francis A, Watson M, Vincent TL, Woollacott S, Mackworth-Young C, Glover V, Furniss D, Gardiner M, Lamb SE, Vincent K, Barber VS, Black J, Dutton SJ, Watt FE. Marian IR, et al. Pilot Feasibility Stud. 2021 Jun 24;7(1):133. doi: 10.1186/s40814-021-00869-1. Pilot Feasibility Stud. 2021. PMID: 34167594 Free PMC article.
BACKGROUND: Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the age of the menopause. ...It will provide proof-of-concept RCT data on the effects of HRT on hand p
BACKGROUND: Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher …
(18) Fluorine-fluorodeoxyglucose positron emission tomography for assessment of deep digital flexor tendinopathy: An exploratory study in eight horses with comparison to CT and MRI.
Wilson S, Spriet M, Mur PE, Anishchenko S, Beylin D, Katzman S, Galuppo L. Wilson S, et al. Vet Radiol Ultrasound. 2021 Jun 20. doi: 10.1111/vru.13001. Online ahead of print. Vet Radiol Ultrasound. 2021. PMID: 34148276
The aims of this exploratory, prospective, methods comparison study were to assess the ability of (18) fluorine-fluorodeoxyglucose ((18) F-FDG) PET to detect DDFT lesions and to compare the PET findings with CT and MRI findings. Eight horses with lameness due to pain
The aims of this exploratory, prospective, methods comparison study were to assess the ability of (18) fluorine-fluorodeoxyglucose ((18) F-F …
Equine "Idiopathic" and Infundibular Caries-Related Cheek Teeth Fractures: A Long-Term Study of 486 Fractured Teeth in 300 Horses.
Dixon PM, Kennedy R, Reardon RJM. Dixon PM, et al. Front Vet Sci. 2021 May 28;8:646870. doi: 10.3389/fvets.2021.646870. eCollection 2021. Front Vet Sci. 2021. PMID: 34124217 Free PMC article.
Results: Records of 300 horses with 486 non-traumatic cheek teeth fractures including 77% maxillary and 23% mandibular teeth with a mean of 1.6 (range 1-10) fractured teeth/horse were available. ...The Triadan 08 and 09 positions were the most commonly (64%) fractur …
Results: Records of 300 horses with 486 non-traumatic cheek teeth fractures including 77% maxillary and 23% mandibular teeth with a m …
Acute Central Nervous System Trauma in the Field.
Estell K. Estell K. Vet Clin North Am Equine Pract. 2021 Aug;37(2):245-258. doi: 10.1016/j.cveq.2021.04.001. Epub 2021 Jun 10. Vet Clin North Am Equine Pract. 2021. PMID: 34119403 Review.
The skull and vertebral canal are complex 3-dimensional structures, and orthogonal radiographic views are necessary for an accurate diagnosis. Therapeutics aimed at decreasing pain, inflammation, and edema or increased intracranial pressure in the case of traumatic brain i …
The skull and vertebral canal are complex 3-dimensional structures, and orthogonal radiographic views are necessary for an accurate diagnosi …
Gastric and Large Colon Impactions Combined With Aggressive Enteral Fluid Therapy May Predispose to Large Colon Volvulus: 4 Cases.
Giusto G, Cerullo A, Gandini M. Giusto G, et al. J Equine Vet Sci. 2021 Jul;102:103617. doi: 10.1016/j.jevs.2021.103617. Epub 2021 Apr 18. J Equine Vet Sci. 2021. PMID: 34119200
In all cases a sudden increase in pain was noticed shortly after enteral administration of large volumes (8-10 liters) of water. Administration of analgesic didn't resolve the pain in any of the horses that were then referred. A large colon volvulus was found …
In all cases a sudden increase in pain was noticed shortly after enteral administration of large volumes (8-10 liters) of water. Admi …
Retrospective analysis of horses with ultrasound evaluation of the sacroiliac region and response to local corticosteroid injection: 42 cases.
Ellis KL, Seabaugh K, King MR. Ellis KL, et al. J Equine Vet Sci. 2021 Jul;102:103634. doi: 10.1016/j.jevs.2021.103634. Epub 2021 Apr 29. J Equine Vet Sci. 2021. PMID: 34119197
Local injection of corticosteroids is commonly performed in horses with sacroiliac (SI) region pain and/or dysfunction, ,and ultrasound findings of normal horses and those with SI pain have also been well described. ...A client survey was sent to deter …
Local injection of corticosteroids is commonly performed in horses with sacroiliac (SI) region pain and/or dysfunction, ,and u …
Gross post-mortem and histological features in 27 horses with confirmed lumbosacral region pain and five control horses: A descriptive cadaveric study.
Quiney L, Stewart J, Routh J, Dyson S. Quiney L, et al. Equine Vet J. 2021 Jun 12. doi: 10.1111/evj.13488. Online ahead of print. Equine Vet J. 2021. PMID: 34118082
Horses for which the source(s) of pain was confirmed by diagnostic anaesthesia to be distant to the lumbosacral region were included in the control group (n = 5). ...Neural pain may play an important role in some horses....
Horses for which the source(s) of pain was confirmed by diagnostic anaesthesia to be distant to the lumbosacral region
Development and Validation of a Three-Dimensional Printed Training Model to Teach Ultrasound-Guided Injections of the Cervical Articular Process Joints in Horses.
Beaulieu A, Nykamp S, Phillips J, Arroyo LG, Koenig J, Zur Linden A. Beaulieu A, et al. J Vet Med Educ. 2021 Jun 11:e20200137. doi: 10.3138/jvme-2020-0137. Online ahead of print. J Vet Med Educ. 2021. PMID: 34115577
Intra-articular injections are routinely performed to alleviate pain and inflammation associated with osteoarthritis in horses. Intra-articular injections require accurate needle placement to optimize clinical outcomes and minimize complications. This study's
Intra-articular injections are routinely performed to alleviate pain and inflammation associated with osteoarthritis in horses
Effect of transportation and social isolation on facial expressions of healthy horses.
Lundblad J, Rashid M, Rhodin M, Haubro Andersen P. Lundblad J, et al. PLoS One. 2021 Jun 4;16(6):e0241532. doi: 10.1371/journal.pone.0241532. eCollection 2021. PLoS One. 2021. PMID: 34086704 Free PMC article.
Transportation was performed in 28 horses by subjecting them to short-term road transport in a horse trailer. ...Several features identified in this study of pain-free horses, such as dilated nostrils, eye white increase, and inner brow raiser, are use …
Transportation was performed in 28 horses by subjecting them to short-term road transport in a horse trailer. ...Several featu …
Spontaneous Behaviors of Post-Orchiectomy Pain in Horses Regardless of the Effects of Time of Day, Anesthesia, and Analgesia.
Trindade PHE, Taffarel MO, Luna SPL. Trindade PHE, et al. Animals (Basel). 2021 May 31;11(6):1629. doi: 10.3390/ani11061629. Animals (Basel). 2021. PMID: 34072875 Free PMC article.
This prospective and longitudinal study aimed to identify spontaneous post-orchiectomy pain behaviors in horses regardless of the effects of anesthesia, analgesia, and recording time of day. ...In conclusion, confounding factors rather than pain may influence …
This prospective and longitudinal study aimed to identify spontaneous post-orchiectomy pain behaviors in horses regardless of …
A study of ultrasound-guided perineural injection of the caudal cervical spinal nerve roots in equine cadavers.
Cruz-Sanabria JA, Gaschen L, Bragulla HH, Mitchell M, Leise BS. Cruz-Sanabria JA, et al. Vet Anaesth Analg. 2021 Jul;48(4):603-611. doi: 10.1016/j.vaa.2021.04.002. Epub 2021 May 5. Vet Anaesth Analg. 2021. PMID: 34059458
This technique could potentially be used for the diagnosis and treatment of cervical pain in horses, particularly in cases where intra-articular cervical articular process joint injections have not been beneficial. Further studies are necessary to assess the effecti …
This technique could potentially be used for the diagnosis and treatment of cervical pain in horses, particularly in cases whe …
Rare shear-type fracture of the talar head in a thirteen-year-old child - Is this a transitional fracture: A case report and review of the literature.
Monestier L, Riva G, Faoro L, Surace MF. Monestier L, et al. World J Orthop. 2021 May 18;12(5):329-337. doi: 10.5312/wjo.v12.i5.329. eCollection 2021 May 18. World J Orthop. 2021. PMID: 34055590 Free PMC article.
CASE SUMMARY: A thirteen-year-old girl reported a high-energy trauma to her right foot, due to falling from her horse. X-rays at the Emergency Department were negative. Because of persistent pain, the patient was assessed by an orthopedic surgeon after two weeks and …
CASE SUMMARY: A thirteen-year-old girl reported a high-energy trauma to her right foot, due to falling from her horse. X-rays at the …
Trichinella Spiralis.
Rawla P, Sharma S. Rawla P, et al. 2021 May 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. 2021 May 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. PMID: 30860746 Free Books & Documents. Review.
Trichinella spiralis species is the common cause of human disease by eating raw or undercooked pork. Other mammals like wild carnivores and horses can be reservoirs of infection. It can cause symptoms varying from generalized fever, abdominal pain, diarrhea, nausea, …
Trichinella spiralis species is the common cause of human disease by eating raw or undercooked pork. Other mammals like wild carnivores and …
Heterotopic Polyodontia: Diagnosis and Surgical Removal of a Dentigerous Cyst Comprising 2 Dental Structures in a 14-Year-Old Horse.
Platt JP, MacDonald DG, Selberg K, Jackman BR. Platt JP, et al. J Vet Dent. 2021 Mar;38(1):30-33. doi: 10.1177/08987564211018522. Epub 2021 May 25. J Vet Dent. 2021. PMID: 34032162
A 14-year-old American Paint Horse mare was referred for further evaluation of a firm mass with an associated draining tract at the base of the left ear suspected to be a dentigerous cyst. ...Physical examination revealed a firm mass palpable at the base of the left ear wi …
A 14-year-old American Paint Horse mare was referred for further evaluation of a firm mass with an associated draining tract at the b …
Gene transcripts expressed in equine white blood cells are potential biomarkers of extracorporeal shock wave therapy.
Jiang Z, Chen JW, Haughan J, Stefanovski D, Soma LR, Robinson MA. Jiang Z, et al. Drug Test Anal. 2021 May 18. doi: 10.1002/dta.3099. Online ahead of print. Drug Test Anal. 2021. PMID: 34008346
Extracorporeal shockwave therapy (ESWT) is a treatment applied to musculoskeletal injuries in equine athletes to alleviate pain and accelerate healing. ESWT also causes acute tissue damage. ...While ESWT is prohibited by many racing jurisdictions within 10 days prior to co …
Extracorporeal shockwave therapy (ESWT) is a treatment applied to musculoskeletal injuries in equine athletes to alleviate pain and a …
A Conservative Management of Spontaneously Ruptured Liver Hydatid Cyst.
Obeid M, Mansour S, Damouny M, Farah A, Halloun K, Marjiyeh R, Ghalia J, Khuri S. Obeid M, et al. Gastroenterology Res. 2021 Apr;14(2):125-128. doi: 10.14740/gr1373. Epub 2021 Apr 21. Gastroenterology Res. 2021. PMID: 34007355 Free PMC article.
Hydatid disease is a zoonotic disease caused mainly by the cestode (tapeworm) Echinococcus granulosus, also known as hydatidosis. It is endemic mainly in areas where dog/horse breeding and sheep farming are common, such as Australia, New Zealand and the Mediterranean regio …
Hydatid disease is a zoonotic disease caused mainly by the cestode (tapeworm) Echinococcus granulosus, also known as hydatidosis. It is ende …
Impacts of DigestaWell NRG Supplementation on Post Exercise Muscle Soreness in Unconditioned Horses, a Pilot Study.
Suagee-Bedore JK, Shen Y, Porr S, Girard ID, Bennett-Wimbush K, Wagner AL. Suagee-Bedore JK, et al. J Equine Vet Sci. 2021 Jun;101:103455. doi: 10.1016/j.jevs.2021.103455. Epub 2021 Mar 25. J Equine Vet Sci. 2021. PMID: 33993938
Exercising horses are commonly plagued by muscle fatigue and soreness, which can result in reduced performance ability. In the present study, ten unconditioned horses were fed 200g per day DigestaWell NRG, a commercial dietary supplement containing Yucca schidigera …
Exercising horses are commonly plagued by muscle fatigue and soreness, which can result in reduced performance ability. In the presen …
EOTRH Syndrome in Polish Half-Bred Horses - Two Clinical Cases.
Górski K, Tremaine H, Obrochta B, Buczkowska R, Turek B, Bereznowski A, Rakowska A, Polkowska I. Górski K, et al. J Equine Vet Sci. 2021 Jun;101:103428. doi: 10.1016/j.jevs.2021.103428. Epub 2021 Feb 24. J Equine Vet Sci. 2021. PMID: 33993931
Most recent reports show that it is a common problem involving older equine patients. The most common and significant symptom of EOTRH is oral pain. The main clinical signs include periodontitis and gingivitis with a gingival recession, alveolar bone protrusion, periodonti …
Most recent reports show that it is a common problem involving older equine patients. The most common and significant symptom of EOTRH is or …
Systematic literature review and network Meta-analysis of sulodexide and other drugs in chronic venous disease.
Pompilio G, Nicolaides A, Kakkos SK, Integlia D. Pompilio G, et al. Phlebology. 2021 May 13:2683555211015020. doi: 10.1177/02683555211015020. Online ahead of print. Phlebology. 2021. PMID: 33983078
OBJECTIVE: To assess the clinical efficacy of sulodexide, including a comparison with venoactive drugs (VAD) (micronized purified flavonoid fraction, MPFF; hydroxy-ethyl-rutosides, HR; calcium dobesilate;Ruscus extract combined with hesperidin methyl chalcone and vitamin C, Ruscu …
OBJECTIVE: To assess the clinical efficacy of sulodexide, including a comparison with venoactive drugs (VAD) (micronized purified flavonoid …
Towards an improved pain assessment in castrated horses using facial expressions (HGS) and circulating miRNAs.
Dalla Costa E, Dai F, Lecchi C, Ambrogi F, Lebelt D, Stucke D, Ravasio G, Ceciliani F, Minero M. Dalla Costa E, et al. Vet Rec. 2021 May;188(9):e82. doi: 10.1002/vetr.82. Epub 2021 Feb 2. Vet Rec. 2021. PMID: 33960478
BACKGROUND: Pain in horses is an emergent welfare concern, and its assessment represents a challenge for equine clinicians. ...CONCLUSIONS: Combining the use of HGS and circulating miRNAs, particularly miR-145, could be meaningful to monitor acute pain condit …
BACKGROUND: Pain in horses is an emergent welfare concern, and its assessment represents a challenge for equine clinicians. .. …
Type, prevalence, and risk factors for the development of orthopedic injuries in endurance horses during training and competition.
Paris A, Beccati F, Pepe M. Paris A, et al. J Am Vet Med Assoc. 2021 May 15;258(10):1109-1118. doi: 10.2460/javma.258.10.1109. J Am Vet Med Assoc. 2021. PMID: 33944587
OBJECTIVE: To report the type, prevalence, and risk factors for the development of orthopedic injuries in endurance horses. ANIMALS: 235 endurance horses. PROCEDURES: Medical records of horses examined between January 2007 and December 2018 were reviewed. ... …
OBJECTIVE: To report the type, prevalence, and risk factors for the development of orthopedic injuries in endurance horses. ANIMALS: …
Pharmacokinetics and pharmacodynamics of a high concentration of buprenorphine (Simbadol) in conscious horses after subcutaneous administration.
Flynn H, Cenani A, Brosnan RJ, DiMaio Knych HK, de Araujo Aguiar AJ. Flynn H, et al. Vet Anaesth Analg. 2021 Jul;48(4):585-595. doi: 10.1016/j.vaa.2021.02.005. Epub 2021 Mar 22. Vet Anaesth Analg. 2021. PMID: 33934992
CONCLUSIONS AND CLINICAL RELEVANCE: In horses, SC Simbadol was rapidly absorbed and C(p) decreased rapidly. ...Simbadol (0.0025 mg kg(-1)) SC has the potential to be used clinically to treat pain in horses. However, at this dose, duration of antinociceptive e …
CONCLUSIONS AND CLINICAL RELEVANCE: In horses, SC Simbadol was rapidly absorbed and C(p) decreased rapidly. ...Simbadol (0.0025 mg kg …
Isolation of Moraxella spp. from horses with conjunctivitis in Southern Brazil.
Seeger MG, Corrêa LFD, Clothier KA, Loy JD, Cargnelutti JF. Seeger MG, et al. Braz J Microbiol. 2021 Sep;52(3):1643-1648. doi: 10.1007/s42770-021-00507-1. Epub 2021 Apr 30. Braz J Microbiol. 2021. PMID: 33931826
The economic impact of IKC is mainly due to ocular damage, which leads to weight loss, management difficulties, pain and discomfort, and cost of treatments. In horses, limited information is available on the association of Moraxella spp. with keratoconjunctivitis. . …
The economic impact of IKC is mainly due to ocular damage, which leads to weight loss, management difficulties, pain and discomfort, …
Application of the Ridden Horse Pain Ethogram to Elite Dressage Horses Competing in World Cup Grand Prix Competitions.
Dyson S, Pollard D. Dyson S, et al. Animals (Basel). 2021 Apr 21;11(5):1187. doi: 10.3390/ani11051187. Animals (Basel). 2021. PMID: 33919208 Free PMC article.
There is considerable debate about the social license to compete with horses and controversy about training methods for dressage horses. The objectives were to: 1. apply the Ridden Horse Pain Ethogram (RHpE) to dressage horses competing at elite …
There is considerable debate about the social license to compete with horses and controversy about training methods for dressage h
Perceptions and Attitudes towards Mules in a Group of Soldiers.
Lagos J, Rojas M, Rodrigues JB, Tadich T. Lagos J, et al. Animals (Basel). 2021 Apr 3;11(4):1009. doi: 10.3390/ani11041009. Animals (Basel). 2021. PMID: 33916720 Free PMC article.
This study intends to assess the perceptions, attitudes, empathy and pain perception of soldiers about mules, to understand the type of human-mule relationship. ...Significant positive correlations were found between human empathy, animal empathy and pain perception …
This study intends to assess the perceptions, attitudes, empathy and pain perception of soldiers about mules, to understand the type …
Short-term infusion of ultralow-dose dopamine in an adult horse with acute kidney injury: A case report.
Matsuda H, Matsuda K, Muko R, Oikawa MA, Tanaka A. Matsuda H, et al. Vet Anim Sci. 2021 Apr 11;12:100176. doi: 10.1016/j.vas.2021.100176. eCollection 2021 Jun. Vet Anim Sci. 2021. PMID: 33912729 Free PMC article.
Low-dose dopamine (1 to 5 mug/kg bwt per min) is a treatment option for AKI in humans but remains controversial for use in horses because of the lack of extensive clinical trial data. A 19-year-old Westfalen horse gelding was referred to the Animal Medical Center wi …
Low-dose dopamine (1 to 5 mug/kg bwt per min) is a treatment option for AKI in humans but remains controversial for use in horses bec …
Iron-withdrawing anti-infectives for new host-directed therapies based on iron dependence, the Achilles' heel of antibiotic-resistant microbes.
Holbein BE, Ang MTC, Allan DS, Chen W, Lehmann C. Holbein BE, et al. Environ Chem Lett. 2021 Apr 23:1-20. doi: 10.1007/s10311-021-01242-7. Online ahead of print. Environ Chem Lett. 2021. PMID: 33907538 Free PMC article. Review.
Of the three therapeutic approaches available to exploit microbial iron susceptibility, including (1) use of gallium as a non-functional iron analogue, (2) Trojan horse conjugates of microbial siderophores carrying antibiotics, and (3) new generation iron chelators, purpos …
Of the three therapeutic approaches available to exploit microbial iron susceptibility, including (1) use of gallium as a non-functional iro …
Laparoscopic closure of the vaginal rings in the standing horse using a tacked intraperitoneal slitted mesh (TISM) technique.
Wilderjans H, Meulyzer M. Wilderjans H, et al. Equine Vet J. 2021 Apr 17. doi: 10.1111/evj.13454. Online ahead of print. Equine Vet J. 2021. PMID: 33864714
RESULTS: A total of 32 laparoscopic vaginal rings closures were successfully performed in 17 horses. No major intra- or postoperative complications occurred. None of the horse suffered from re-occurrence. ...In three stallions, post-operative pain and activit …
RESULTS: A total of 32 laparoscopic vaginal rings closures were successfully performed in 17 horses. No major intra- or postoperative …
Movement asymmetries in horses presented for prepurchase or lameness examination.
Hardeman AM, Egenvall A, Serra Bragança FM, Koene MHW, Swagemakers JH, Roepstorff L, van Weeren R, Byström A. Hardeman AM, et al. Equine Vet J. 2021 Apr 16. doi: 10.1111/evj.13453. Online ahead of print. Equine Vet J. 2021. PMID: 33862666
Lame horses were only included if pain-related lameness was confirmed by an objective improvement after diagnostic analgesia exceeding daily variation determined for equine symmetry parameters using optical motion capture. ...Correcting for vertical range of motion …
Lame horses were only included if pain-related lameness was confirmed by an objective improvement after diagnostic analgesia e …
Experiences of Military Veterans in a Therapeutic Horseback Riding Program.
Johnson RA, Albright DL, Marzolf JR, Bibbo JL, Yaglom HD, Crowder SM, Carlisle GM, Grindler K, Harms N, Willard A, Wassman M, Russell CL. Johnson RA, et al. Clin Nurs Res. 2021 Sep;30(7):923-933. doi: 10.1177/10547738211003580. Epub 2021 Apr 15. Clin Nurs Res. 2021. PMID: 33855883
Posttraumatic stress disorder commonly occurs among U.S. military veterans. Therapeutic horseback riding (THR) has emerged as an adjunct therapy. ...Drawbacks were "None," "Struggle to Get There," "Pain," "Too Short," and "It is Structured." Overall perceptions were …
Posttraumatic stress disorder commonly occurs among U.S. military veterans. Therapeutic horseback riding (THR) has emerged as an adju …
Outcomes after cervical vertebral interbody fusion using an interbody fusion device and polyaxial pedicle screw and rod construct in 10 horses (2015-2019).
Pezzanite LM, Easley JT, Bayless R, Aldrich E, Nelson BB, Seim HB 3rd, Nout-Lomas YS. Pezzanite LM, et al. Equine Vet J. 2021 Apr 12. doi: 10.1111/evj.13449. Online ahead of print. Equine Vet J. 2021. PMID: 33844334
Fusion was performed at one (n = 3) or two (n = 7) sites. Two horses were euthanised within the first year. In 6 of 8 horses with 1-year follow-up, ataxia improved by 1-3 grades, with an average improvement of 1.25 grades. In four horses, ataxia improved to g …
Fusion was performed at one (n = 3) or two (n = 7) sites. Two horses were euthanised within the first year. In 6 of 8 horses w …
Clinical insights: Equine analgesia.
Mackenzie C. Mackenzie C. Equine Vet J. 2021 May;53(3):407-409. doi: 10.1111/evj.13421. Equine Vet J. 2021. PMID: 33834534 No abstract available.
A Comparison of the Colonic Microbiome and Volatile Organic Compound Metabolome of Anoplocephala perfoliata Infected and Non-Infected Horses: A Pilot Study.
Slater R, Frau A, Hodgkinson J, Archer D, Probert C. Slater R, et al. Animals (Basel). 2021 Mar 9;11(3):755. doi: 10.3390/ani11030755. Animals (Basel). 2021. PMID: 33803473 Free PMC article.
Anoplocephala perfoliata is a common equine tapeworm associated with an increased risk of colic (abdominal pain) in horses. Identification of parasite and intestinal microbiota interactions have consequences for understanding the mechanisms behind parasite-associate …
Anoplocephala perfoliata is a common equine tapeworm associated with an increased risk of colic (abdominal pain) in horses. Id …
Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model.
Bertoni L, Jacquet-Guibon S, Branly T, Desancé M, Legendre F, Melin M, Rivory P, Hartmann DJ, Schmutz A, Denoix JM, Demoor M, Audigié F, Galéra P. Bertoni L, et al. Int J Mol Sci. 2021 Mar 2;22(5):2499. doi: 10.3390/ijms22052499. Int J Mol Sci. 2021. PMID: 33801461 Free PMC article.
Osteoarthritis (OA) is a significant cause of pain in both humans and horses with a high socio-economic impact. ...These results indicate that allogeneic BM-MSCs are a promising treatment for OA in horses and reinforce the importance of continuing research to …
Osteoarthritis (OA) is a significant cause of pain in both humans and horses with a high socio-economic impact. ...These resul …
Comparison of sedation quality and safety of detomidine and romifidine as a continuous rate infusion for standing elective laparoscopic ovariectomy in mares.
Lawless SP, Moorman VJ, Hendrickson DA, Mama KR. Lawless SP, et al. Vet Surg. 2021 Jul;50(5):990-998. doi: 10.1111/vsu.13627. Epub 2021 Apr 1. Vet Surg. 2021. PMID: 33797093
Intraoperative measurements included respiratory rate, heart rate, head height, postural sway, and response to surgical stimulus. Postoperatively, fecal output was recorded, and pain scoring was performed using composite pain score and visual analog scales. RESULTS: …
Intraoperative measurements included respiratory rate, heart rate, head height, postural sway, and response to surgical stimulus. Postoperat …
Horse-riding simulators in treatment of chronic low back pain: A meta-analysis.
Ren C, Liu T, Zhang J. Ren C, et al. Int J Clin Pract. 2021 Jul;75(7):e14198. doi: 10.1111/ijcp.14198. Epub 2021 Apr 8. Int J Clin Pract. 2021. PMID: 33792117
They reported a comparison between horse-riding simulators and control to reduce chronic low back pain. ...CONCLUSIONS: Using horse-riding simulators may lower the risk of chronic low back pain. ...
They reported a comparison between horse-riding simulators and control to reduce chronic low back pain. ...CONCLUSIONS: Using …
"Feel the Force"-Prevalence of Subjectively Assessed Saddle Fit Problems in Swiss Riding Horses and Their Association With Saddle Pressure Measurements and Back Pain.
Dittmann MT, Arpagaus S, Hungerbühler V, Weishaupt MA, Latif SN. Dittmann MT, et al. J Equine Vet Sci. 2021 Apr;99:103388. doi: 10.1016/j.jevs.2021.103388. Epub 2021 Jan 20. J Equine Vet Sci. 2021. PMID: 33781419
Pressures exceeded clinically relevant thresholds in 15% of the horses. There was no clear correlation between back pain and pressure magnitude, but back pain was associated with certain subjectively assessed fit problems. ...Pressure magnitude showed only li …
Pressures exceeded clinically relevant thresholds in 15% of the horses. There was no clear correlation between back pain and p …
The Evaluation of Equine Allogeneic Tenogenic Primed Mesenchymal Stem Cells in a Surgically Induced Superficial Digital Flexor Tendon Lesion Model.
Depuydt E, Broeckx SY, Van Hecke L, Chiers K, Van Brantegem L, van Schie H, Beerts C, Spaas JH, Pille F, Martens A. Depuydt E, et al. Front Vet Sci. 2021 Mar 5;8:641441. doi: 10.3389/fvets.2021.641441. eCollection 2021. Front Vet Sci. 2021. PMID: 33748217 Free PMC article.
Background: Tendon injuries are very common in horses and jeopardize the athletic performance, and due to the high risk of reinjury may lead to early retirement. ...The objective of this study is to investigate the safety and efficacy of equine allogeneic tenogenic primed …
Background: Tendon injuries are very common in horses and jeopardize the athletic performance, and due to the high risk of reinjury m …
Use of Crotalidae equine immune F(ab')2 antivenom for treatment of an Agkistrodon envenomation.
Wilson BZ, Larsen J, Smelski G, Dudley S, Shirazi FM. Wilson BZ, et al. Clin Toxicol (Phila). 2021 Mar 11:1-4. doi: 10.1080/15563650.2021.1892718. Online ahead of print. Clin Toxicol (Phila). 2021. PMID: 33703984
INTRODUCTION: Anavip (F(ab')(2)AV) is a lyophilized F(ab')(2) immunoglobulin fragment derived from horses immunized with venom from Bothrops asper and Crotalus durissus. ...He was taken to a local emergency department where he received a 10 vial initial dose of F(ab')(2)AV …
INTRODUCTION: Anavip (F(ab')(2)AV) is a lyophilized F(ab')(2) immunoglobulin fragment derived from horses immunized with venom from B …
Antinociceptive effects of levomethadone in standing horses sedated with romifidine.
Studer N, Bernal SD, Thormann W, Levionnois O, Spadavecchia C. Studer N, et al. Vet Anaesth Analg. 2021 May;48(3):451-460. doi: 10.1016/j.vaa.2020.08.011. Epub 2021 Feb 2. Vet Anaesth Analg. 2021. PMID: 33685821
ANIMALS: A group of eight adult Warmblood horses (seven geldings, one mare) aged 6.6 4.4 years, weighing 548 52 kg [mean standard deviation (SD)]. ...CONCLUSIONS AND CLINICAL RELEVANCE: A single injection of levomethadone has the potential to increase the NWRT during romif …
ANIMALS: A group of eight adult Warmblood horses (seven geldings, one mare) aged 6.6 4.4 years, weighing 548 52 kg [mean standard dev …
Equine Discomfort Ethogram.
Torcivia C, McDonnell S. Torcivia C, et al. Animals (Basel). 2021 Feb 23;11(2):580. doi: 10.3390/ani11020580. Animals (Basel). 2021. PMID: 33672338 Free PMC article.
In recent years, there has been a growing interest in and need for a comprehensive ethogram of discomfort behavior of horses, particularly for use in recognizing physical discomfort in domestically managed horses. ...This ethogram, unambiguously describing equine di …
In recent years, there has been a growing interest in and need for a comprehensive ethogram of discomfort behavior of horses, particu …
An Investigation Into the Short-Term Effects of Photobiomodulation on the Mechanical Nociceptive Thresholds of M. Longissimus and M. Gluteus Medius, in Relation to Muscle Firing Rate in Horses at Three Different Gaits.
Ahmed W, Elbrønd VS, Harrison AP, Hart JO, Williams RE. Ahmed W, et al. J Equine Vet Sci. 2021 Mar;98:103363. doi: 10.1016/j.jevs.2020.103363. Epub 2020 Dec 24. J Equine Vet Sci. 2021. PMID: 33663728
Back pain is a common condition in horses, yet despite this, quantitative assessments of the efficacy of treatment are scarce. ...It is concluded that cold laser therapy has a positive effect on horse muscles that reveals a change in their firing frequency th …
Back pain is a common condition in horses, yet despite this, quantitative assessments of the efficacy of treatment are scarce. …
Effects of Intravenous Flunixin Meglumine, Phenylbutazone, and Acupuncture on Ocular Pain Scores in the Horse: A Pilot Study.
Makra Z, Csereklye N, Riera MM, McMullen RJ Jr, Veres-Nyéki K. Makra Z, et al. J Equine Vet Sci. 2021 Mar;98:103375. doi: 10.1016/j.jevs.2021.103375. Epub 2021 Jan 6. J Equine Vet Sci. 2021. PMID: 33663725
In this controlled, blinded, randomized block pilot study, the main objective was to evaluate the effectiveness of intravenous flunixin meglumine, phenylbutazone, and acupuncture on ocular pain relief using a multifactorial pain scale in the horse. Four exper …
In this controlled, blinded, randomized block pilot study, the main objective was to evaluate the effectiveness of intravenous flunixin megl …
Complications following equine sacroiliac region analgesia are uncommon: A study in 118 horses.
Offord SCJ, Read RM, Pudney CJ, Bathe AP. Offord SCJ, et al. PLoS One. 2021 Mar 2;16(3):e0247781. doi: 10.1371/journal.pone.0247781. eCollection 2021. PLoS One. 2021. PMID: 33651806 Free PMC article.
BACKGROUND: Diagnosis of sacroiliac region pain is supported by a positive response to sacroiliac region analgesia (SIRA). ...Injection was performed using a blind midline approach with 20 mL mepivacaine (Intra-Epicaine 20mg/ml; Dechra) infiltrated through a straight 18 ga …
BACKGROUND: Diagnosis of sacroiliac region pain is supported by a positive response to sacroiliac region analgesia (SIRA). ...Injecti …
Anisakiasis of the Terminal Ileum Removed by Colonoscopy.
Okamoto T, Fukuda K. Okamoto T, et al. Case Rep Gastroenterol. 2021 Jan 25;15(1):47-52. doi: 10.1159/000509949. eCollection 2021 Jan-Apr. Case Rep Gastroenterol. 2021. PMID: 33613163 Free PMC article.
A 35-year-old Japanese man with no significant medical history presented to the emergency department complaining of abdominal pain, nausea, and vomiting 35 h after ingesting raw horse mackerel, sardines, and tuna. ...On colonoscopy, an actively moving anisakis larva …
A 35-year-old Japanese man with no significant medical history presented to the emergency department complaining of abdominal pain, n …
The effect of regional hypothermia on mechanical nociceptive thresholds in the equine distal forelimb.
Rainger JE, Wardius S, Medina-Torres CE, Dempsey SM, Perkins N, van Eps AW. Rainger JE, et al. Vet J. 2021 Mar;269:105607. doi: 10.1016/j.tvjl.2021.105607. Epub 2021 Jan 6. Vet J. 2021. PMID: 33593491
Regional hypothermia has shown promise as analgesic in horses when used to manage painful conditions of the distal limb such as laminitis. ...The study population consisted of eight healthy adult Standardbred horses, selected from a teaching herd. A distal forelimb …
Regional hypothermia has shown promise as analgesic in horses when used to manage painful conditions of the distal limb such as lamin …
Training Young Horses: The Science behind the Benefits.
Logan AA, Nielsen BD. Logan AA, et al. Animals (Basel). 2021 Feb 9;11(2):463. doi: 10.3390/ani11020463. Animals (Basel). 2021. PMID: 33572461 Free PMC article. Review.
Conflicting research and anecdotal evidence have created disagreement among equestrians as to whether two-year-old horses should be trained and raced. The objective of this literature review is to evaluate epidemiological studies, as well as physiological data on equine bo …
Conflicting research and anecdotal evidence have created disagreement among equestrians as to whether two-year-old horses should be t …
Retrospective analysis of oblique and straight distal sesamoidean ligament desmitis in 52 horses.
Hawkins A, O'Leary L, Bolt D, Fiske-Jackson A, Berner D, Smith R. Hawkins A, et al. Equine Vet J. 2021 Feb 10. doi: 10.1111/evj.13438. Online ahead of print. Equine Vet J. 2021. PMID: 33567104
BACKGROUND: Injuries to the oblique (ODSL) or straight (SDSL) distal sesamoidean ligaments are a recognised cause of distal limb lameness in the horse. However, there are only limited publications addressing common diagnostic features and prognosis. OBJECTIVES: (a) Report …
BACKGROUND: Injuries to the oblique (ODSL) or straight (SDSL) distal sesamoidean ligaments are a recognised cause of distal limb lameness in …
Equine Cervical Pain and Dysfunction: Pathology, Diagnosis and Treatment.
Story MR, Haussler KK, Nout-Lomas YS, Aboellail TA, Kawcak CE, Barrett MF, Frisbie DD, McIlwraith CW. Story MR, et al. Animals (Basel). 2021 Feb 6;11(2):422. doi: 10.3390/ani11020422. Animals (Basel). 2021. PMID: 33562089 Free PMC article. Review.
Interest in the cervical spine as a cause of pain or dysfunction is increasingly becoming the focus of many equine practitioners. ...There are multiple treatment options available and each must be carefully chosen for an individual horse. Provided is a synopsis of t …
Interest in the cervical spine as a cause of pain or dysfunction is increasingly becoming the focus of many equine practitioners. ... …
Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative.
Hammock BD, McReynolds CB, Wagner K, Buckpitt A, Cortes-Puch I, Croston G, Lee KSS, Yang J, Schmidt WK, Hwang SH. Hammock BD, et al. J Med Chem. 2021 Feb 25;64(4):1856-1872. doi: 10.1021/acs.jmedchem.0c01886. Epub 2021 Feb 7. J Med Chem. 2021. PMID: 33550801 Free PMC article.
This report describes the development of an orally active analgesic that resolves inflammation and neuropathic pain without the addictive potential of opioids. EC5026 acts on the cytochrome P450 branch of the arachidonate cascade to stabilize epoxides of polyunsaturated fa …
This report describes the development of an orally active analgesic that resolves inflammation and neuropathic pain without the addic …
Questionnaire on the process of recovering horses from general anesthesia and associated personnel injury in equine practice.
de Miguel Garcia C, Campoy L, Parry S, Miller JE, Martin-Flores M, Gleed RD. de Miguel Garcia C, et al. Vet Anaesth Analg. 2021 Mar;48(2):223-229. doi: 10.1016/j.vaa.2020.12.005. Epub 2021 Jan 12. Vet Anaesth Analg. 2021. PMID: 33536139
OBJECTIVE: To collect data about the current practice of recovering horses from general anesthesia and recovery personnel safety. STUDY DESIGN: Online survey. ...CONCLUSIONS: The method of recovery differs among hospitals. Recovery personnel injuries associated with assist …
OBJECTIVE: To collect data about the current practice of recovering horses from general anesthesia and recovery personnel safety. STU …
Snake Toxicity.
Meyers SE, Tadi P. Meyers SE, et al. 2021 Jan 31. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. 2021 Jan 31. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. PMID: 32491497 Free Books & Documents. Review.
Patients with venomous snakebites present with signs and symptoms that can include superficial puncture wounds, localized pain and swelling, nausea, vomiting, muscle cramping, dizziness, numbness, tingling around the mouth, dyspnea, life-threatening coagulopathy, and shock …
Patients with venomous snakebites present with signs and symptoms that can include superficial puncture wounds, localized pain and sw …
Experimental evaluation of cortical screw placement in lag fashion into the distal phalanx in standing horses.
Izing S, Béni D, Molnár S, Bakos Z, Bodó G. Izing S, et al. Acta Vet Hung. 2021 Jan 15;68(4):399-404. doi: 10.1556/004.2020.00054. Acta Vet Hung. 2021. PMID: 33459614
The objectives of this in vivo experimental study were to evaluate the feasibility of cortical screw insertion into the intact distal phalanx in standing sedated horses and to document potential postoperative complications. One cortical screw was randomly inserted in lag f …
The objectives of this in vivo experimental study were to evaluate the feasibility of cortical screw insertion into the intact distal phalan …
Stress fracture of the palmar, distal cortex of the third metacarpal bone: A diagnostic challenge with a good prognosis.
Shan R, Johnston AS, Rosanowski SM, O'Shea J, Riggs CM. Shan R, et al. Equine Vet J. 2021 Jan 16. doi: 10.1111/evj.13426. Online ahead of print. Equine Vet J. 2021. PMID: 33454998
Descriptive statistics were used to describe the age and training profile of horses, the clinical and radiological findings and time to return to ridden exercise. ...Sixty-one per cent of cases (14/23) were initially misdiagnosed. Most horses (n = 18/23) resumed tra …
Descriptive statistics were used to describe the age and training profile of horses, the clinical and radiological findings and time …
A Review of Methods for Detecting Soreness in Horses.
National Academies of Sciences, Engineering, and Medicine; Division on Earth and Life Studies; Board on Agriculture and Natural Resources; Committee on a Review of Methods for Detecting Soreness in Horses. National Academies of Sciences, Engineering, and Medicine; Division on Earth and Life Studies; Board on Agriculture and Natural Resources; Committee on a Review of Methods for Detecting Soreness in Horses. Washington (DC): National Academies Press (US); 2021 Jan 13. Washington (DC): National Academies Press (US); 2021 Jan 13. PMID: 34251765 Free Books & Documents. Review.
The combination of exaggerated high-action step in front and long stride behind is still considered desirable in today's horse show competitions, and it is often achieved through soring. Soring is the practice of applying a substance or mechanical device to the lowe …
The combination of exaggerated high-action step in front and long stride behind is still considered desirable in today's horse
Rare case of right ventricular dilatation associated with anomalous pulmonary venous drainage, sinus venosus atrial septal defect and persistent left superior vena cava.
Rees S, Tahir M, Ahmad SJ, Subkovas E. Rees S, et al. BMJ Case Rep. 2021 Jan 11;14(1):e239687. doi: 10.1136/bcr-2020-239687. BMJ Case Rep. 2021. PMID: 33431524
A 34-year-old woman was seen in the emergency department for shortness of breath and chest pain. During a pandemic, it is easy to 'think horses and not zebras', and with a patient presenting with the classic coronavirus symptoms it would have been easy to jump to th …
A 34-year-old woman was seen in the emergency department for shortness of breath and chest pain. During a pandemic, it is easy to 'th …
The application of a new laminitis scoring method to model the rate and pattern of improvement from equine endocrinopathic laminitis in a clinical setting.
Meier A, McGree J, Klee R, Preuß J, Reiche D, de Laat M, Sillence M. Meier A, et al. BMC Vet Res. 2021 Jan 7;17(1):16. doi: 10.1186/s12917-020-02715-7. BMC Vet Res. 2021. PMID: 33413384 Free PMC article.
Assessments were made on the day of diagnosis (d 0), then on days 4, 9, 14, 25 and 42 during the intervention period. Pain medications were withheld for 24 h prior to clinical examination in all cases. ...More subtle changes could be identified using the Meier method, howe …
Assessments were made on the day of diagnosis (d 0), then on days 4, 9, 14, 25 and 42 during the intervention period. Pain medication …
Intra-articular use of analgesic/antinflammatory drugs in dogs and horses.
Di Salvo A, Chiaradia E, Nannarone S, Della Rocca G. Di Salvo A, et al. Res Vet Sci. 2021 Jan;134:159-170. doi: 10.1016/j.rvsc.2020.12.014. Epub 2020 Dec 30. Res Vet Sci. 2021. PMID: 33387756 Review.
Joint pain is a major cause of lameness in animals such as horses and dogs, and it may affect their athletic performance and quality of life. ...This article includes a review of the literature concerning the main analgesic/antinflammatory drugs used intra-articular …
Joint pain is a major cause of lameness in animals such as horses and dogs, and it may affect their athletic performance and q …
Computed tomography identified mineralisation of the longitudinal odontoid ligament of the horse is associated with age and sex but not with the clinical sign of head shaking.
Talbot AM, Rodrigues M, Maddox TW. Talbot AM, et al. Vet Radiol Ultrasound. 2021 May;62(3):289-298. doi: 10.1111/vru.12947. Epub 2021 Jan 1. Vet Radiol Ultrasound. 2021. PMID: 33385302
Mineralisation of the longitudinal odontoid ligament has recently been identified in three horses undergoing computed tomographic (CT) examination, but published studies describing the clinical relevance of this finding are currently lacking. The objective of this retrospe …
Mineralisation of the longitudinal odontoid ligament has recently been identified in three horses undergoing computed tomographic (CT …
Nerve growth factor in the equine joint.
Kendall A, Nyström S, Ekman S, Hultén LM, Lindahl A, Hansson E, Skiöldebrand E. Kendall A, et al. Vet J. 2021 Jan;267:105579. doi: 10.1016/j.tvjl.2020.105579. Epub 2020 Nov 28. Vet J. 2021. PMID: 33375964 Free article.
In humans, it is involved in inflammation, nerve growth, apoptosis and pain signalling. Increased concentrations of NGF in synovial fluid has been shown in humans and dogs with osteoarthritis. Despite osteoarthritis being a common problem in horses, no studies have …
In humans, it is involved in inflammation, nerve growth, apoptosis and pain signalling. Increased concentrations of NGF in synovial f …
Vigorous achalasia: Zebra amongst horses.
Jayabalan J, Theckumparampil N, Natarajan A, Phansalkar DS, Kurian G. Jayabalan J, et al. SA J Radiol. 2020 Nov 30;24(1):1953. doi: 10.4102/sajr.v24i1.1953. eCollection 2020. SA J Radiol. 2020. PMID: 33354369 Free PMC article.
A 60-year-old gentleman presented with complaints of difficulty in swallowing, regurgitation and chest pain for the past 10 years. His symptoms persisted despite the use of proton pump inhibitors. ...
A 60-year-old gentleman presented with complaints of difficulty in swallowing, regurgitation and chest pain for the past 10 years. Hi …
Implications of the neuroanatomy of the equine thoracolumbar vertebral column with regional anaesthesia and complications following desmotomy of the interspinous ligament.
Derham AM, Schumacher J, O' Leary JM, Kelly G, Hahn CN. Derham AM, et al. Equine Vet J. 2021 Jul;53(4):649-655. doi: 10.1111/evj.13402. Epub 2021 Feb 15. Equine Vet J. 2021. PMID: 33336365 Review.
Considering this finding, we have reviewed the literature on the neuroanatomy of the thoracolumbar region in the horse. Literature on the neuroanatomy of the horse is lacking when compared with that of humans and companion animals, with most of the work extrapolated …
Considering this finding, we have reviewed the literature on the neuroanatomy of the thoracolumbar region in the horse. Literature on …
EEG individual power profiles correlate with tension along spine in horses.
Stomp M, d'Ingeo S, Henry S, Lesimple C, Cousillas H, Hausberger M. Stomp M, et al. PLoS One. 2020 Dec 14;15(12):e0243970. doi: 10.1371/journal.pone.0243970. eCollection 2020. PLoS One. 2020. PMID: 33315932 Free PMC article.
Riding horses show a very high prevalence of back disorders thought to be associated with chronic pain. ...Therefore, we hypothesized that the individual EEG power profiles resting state (i.e. quiet standing) of different horses could reflect the state of the …
Riding horses show a very high prevalence of back disorders thought to be associated with chronic pain. ...Therefore, we hypot …
Accelerometric Changes before and after Capacitive Resistive Electric Transfer Therapy in Horses with Thoracolumbar Pain Compared to a SHAM Procedure.
Argüelles D, Becero M, Muñoz A, Saitua A, Ramón T, Gascón E, Sánchez de Medina A, Prades M. Argüelles D, et al. Animals (Basel). 2020 Dec 5;10(12):2305. doi: 10.3390/ani10122305. Animals (Basel). 2020. PMID: 33291357 Free PMC article.
To assess whether CRET would result in clinical and biomechanical improvements in horses with thoracolumbar pain, 18 sport horses were divided into two groups: CRET (n = 9), subjected to four CRET sessions, during two consecutive weeks, and SHAM (n = 9), subj …
To assess whether CRET would result in clinical and biomechanical improvements in horses with thoracolumbar pain, 18 sport …
An assessment of the effectiveness of hyaluronic acid and polyacrylamide hydrogel in horses with osteoarthritis: Systematic review and network meta-analysis.
da Silva Xavier AA, da Rosa PP, de Brum Mackmill L, Roll VFB. da Silva Xavier AA, et al. Res Vet Sci. 2021 Jan;134:42-50. doi: 10.1016/j.rvsc.2020.11.013. Epub 2020 Nov 20. Res Vet Sci. 2021. PMID: 33290979
For several years, hyaluronic acid (HyA) and, more recently, polyacrylamide hydrogel (PHyd) have been used to reduce lameness and pain caused by osteoarthritis. However, there is still a lack of scientific evidence of the efficacy of these substances to allow veterinary ex …
For several years, hyaluronic acid (HyA) and, more recently, polyacrylamide hydrogel (PHyd) have been used to reduce lameness and pain
Duodenal Laceration Due to Blunt Trauma Caused by Horse Kick: A Case Report and Literature Review.
Correia Sousa Périssé JP, de Carvalho Miranda Rosati Rocha AL, Lessa Coelho R, Guerra Campanario B, Rosati Rocha LF. Correia Sousa Périssé JP, et al. Am J Case Rep. 2020 Dec 5;21:e927461. doi: 10.12659/AJCR.927461. Am J Case Rep. 2020. PMID: 33277459 Free PMC article. Review.
We present a rare case of a single duodenal laceration due to blunt abdominal trauma caused by a horse kick, along with a literature review. CASE REPORT A 13-year-old boy presented to our emergency department after being kicked by a horse in his abdomen. He was stab …
We present a rare case of a single duodenal laceration due to blunt abdominal trauma caused by a horse kick, along with a literature …
Functional Electrical Stimulation (FES) and the Effect on Equine Multifidi Asymmetry.
Isbell DA, Schils SJ, Oakley SC, Carraro U, Knaeble BR. Isbell DA, et al. J Equine Vet Sci. 2020 Dec;95:103255. doi: 10.1016/j.jevs.2020.103255. Epub 2020 Sep 28. J Equine Vet Sci. 2020. PMID: 33276934
Asymmetry of the multifidi has been correlated with scoliosis and back pain in humans and has been investigated as a factor in equine back pain as well. ...The FES protocol used in this study has the potential to improve spinal function and assist in reducing back …
Asymmetry of the multifidi has been correlated with scoliosis and back pain in humans and has been investigated as a factor in equine …
Riding Soundness-Comparison of Subjective With Objective Lameness Assessments of Owner-Sound Horses at Trot on a Treadmill.
Müller-Quirin J, Dittmann MT, Roepstorff C, Arpagaus S, Latif SN, Weishaupt MA. Müller-Quirin J, et al. J Equine Vet Sci. 2020 Dec;95:103314. doi: 10.1016/j.jevs.2020.103314. Epub 2020 Nov 1. J Equine Vet Sci. 2020. PMID: 33276930
Lameness is a symptom indicative of pain or injury of the locomotor apparatus. Lame horses generally should not be ridden. However, owners' ability to assess lameness has been questioned. This study's aim was to use subjective lameness assessments and objecti …
Lameness is a symptom indicative of pain or injury of the locomotor apparatus. Lame horses generally should not be ridden. How …
Medicinal Applications of Cannabinoids Extracted from Cannabis sativa (L.): A New Route in the Fight Against COVID-19?
Khalid S, Almalki FA, Hadda TB, Bader A, Abu-Izneid T, Berredjem M, Elsharkawy ER, Alqahtani AM. Khalid S, et al. Curr Pharm Des. 2021;27(13):1564-1578. doi: 10.2174/1381612826666201202125807. Curr Pharm Des. 2021. PMID: 33267756 Review.
This review addresses the most important applications or current utilization of cannabinoids in a variety of treatments such as chronic pain, cancer, emesis, anorexia, irritable bowel syndrome, communicable diseases, glaucoma, and central nervous system disorders. ...
This review addresses the most important applications or current utilization of cannabinoids in a variety of treatments such as chronic p
Development and Validation of an Automated Video Tracking Model for Stabled Horses.
Kil N, Ertelt K, Auer U. Kil N, et al. Animals (Basel). 2020 Nov 30;10(12):2258. doi: 10.3390/ani10122258. Animals (Basel). 2020. PMID: 33266297 Free PMC article.
Therefore, the assessment of behaviour is important for the recognition of pain, but also for the assessment of quality of life. Automated detection of movement and the behaviour of a horse in the box stall should represent a significant advancement. ...By means of …
Therefore, the assessment of behaviour is important for the recognition of pain, but also for the assessment of quality of life. Auto …
Clinical assessment and grading of back pain in horses.
Mayaki AM, Abdul Razak IS, Adzahan NM, Mazlan M, Rasedee A. Mayaki AM, et al. J Vet Sci. 2020 Nov;21(6):e82. doi: 10.4142/jvs.2020.21.e82. J Vet Sci. 2020. PMID: 33263229 Free PMC article.
BACKGROUND: The clinical presentation of horses with back pain (BP) vary considerably with most horse's willingness to take part in athletic or riding purpose becoming impossible. ...The horses were then graded (0-5) using the degree of pain
BACKGROUND: The clinical presentation of horses with back pain (BP) vary considerably with most horse's willingn …
Prospective Feasibility and Revalidation of the Equine Acute Abdominal Pain Scale (EAAPS) in Clinical Cases of Colic in Horses.
Maskato Y, Dugdale AHA, Singer ER, Kelmer G, Sutton GA. Maskato Y, et al. Animals (Basel). 2020 Nov 29;10(12):2242. doi: 10.3390/ani10122242. Animals (Basel). 2020. PMID: 33260428 Free PMC article.
Assessment of the severity of pain in colic cases is subjective. The Equine Acute Abdominal Pain Scale (EAAPS), previously validated using film clips of horses with colic, was tested for feasibility and revalidated in both medical and surgical colic cases in …
Assessment of the severity of pain in colic cases is subjective. The Equine Acute Abdominal Pain Scale (EAAPS), previously val …
Pressure Algometry for the Detection of Mechanical Nociceptive Thresholds in Horses.
Haussler KK. Haussler KK. Animals (Basel). 2020 Nov 24;10(12):2195. doi: 10.3390/ani10122195. Animals (Basel). 2020. PMID: 33255216 Free PMC article. Review.
The clinical assessment of pain is subjective; therefore, variations exist between practitioners in their ability to identify and localize pain. ...There is a critical need to develop better tools to qualify and quantify pain in horses. Palpation is th …
The clinical assessment of pain is subjective; therefore, variations exist between practitioners in their ability to identify and loc …
Identification of Body Behaviors and Facial Expressions Associated with Induced Orthopedic Pain in Four Equine Pain Scales.
Ask K, Rhodin M, Tamminen LM, Hernlund E, Haubro Andersen P. Ask K, et al. Animals (Basel). 2020 Nov 19;10(11):2155. doi: 10.3390/ani10112155. Animals (Basel). 2020. PMID: 33228117 Free PMC article.
Equine orthopedic pain scales are targeted towards horses with moderate to severe orthopedic pain. ...Three observers independently assessed horses in their box stalls, using four equine pain scales simultaneously. ...
Equine orthopedic pain scales are targeted towards horses with moderate to severe orthopedic pain. ...Three observers i …
A Randomized Controlled Trial Investigating the Effects of Equine Simulator Riding on Low Back Pain, Morphological Changes, and Trunk Musculature in Elderly Women.
Park S, Park S, Min S, Kim CJ, Jee YS. Park S, et al. Medicina (Kaunas). 2020 Nov 13;56(11):610. doi: 10.3390/medicina56110610. Medicina (Kaunas). 2020. PMID: 33202928 Free PMC article. Clinical Trial.
Background and objectives: Studies on the effects of an equine riding simulator (ERS) program on back pain, spinal alignment, and isokinetic moments in subjects with chronic low back pain (CLBP) remain limited. ...ERS exercise was performed for a duration of 12 week …
Background and objectives: Studies on the effects of an equine riding simulator (ERS) program on back pain, spinal alignment, and iso …
Standing Sedation and Iocoregional Analgesia in Equine Dental Surgery.
Campoy L, Sedgwick SR. Campoy L, et al. Vet Clin North Am Equine Pract. 2020 Dec;36(3):477-499. doi: 10.1016/j.cveq.2020.08.009. Vet Clin North Am Equine Pract. 2020. PMID: 33189231 Review.
Sedation and local anesthesia for standing diagnostic and surgical procedures on the horse's head circumvents the potential complications of general anesthesia (particularly, complications related to recovery). ...
Sedation and local anesthesia for standing diagnostic and surgical procedures on the horse's head circumvents the potential co …
A Comparative Neuro-Histological Assessment of Gluteal Skin Thickness and Cutaneous Nociceptor Distribution in Horses and Humans.
Tong L, Stewart M, Johnson I, Appleyard R, Wilson B, James O, Johnson C, McGreevy P. Tong L, et al. Animals (Basel). 2020 Nov 11;10(11):2094. doi: 10.3390/ani10112094. Animals (Basel). 2020. PMID: 33187204 Free PMC article.
The thicker collagenous dermis of horse skin may afford some resilience versus external mechanical trauma, though as this is below the pain-detecting nerve endings, it is not considered protective from external cutaneous pain. The superficial pain-sens …
The thicker collagenous dermis of horse skin may afford some resilience versus external mechanical trauma, though as this is below th …
Radiological prevalence of osteoarthritis of the cervical region in 104 performing Warmblood jumpers.
Espinosa-Mur P, Phillips KL, Galuppo LD, DeRouen A, Benoit P, Anderson E, Shaw K, Puchalski S, Peters D, Kass PH, Spriet M. Espinosa-Mur P, et al. Equine Vet J. 2021 Sep;53(5):972-978. doi: 10.1111/evj.13383. Epub 2021 Jan 11. Equine Vet J. 2021. PMID: 33174228
BACKGROUND: Cervical osteoarthritis (OA) has been documented as a potential source of pain and poor performance in sport horses. OBJECTIVES: To assess the prevalence of cervical OA in a population of Warmblood jumpers and its correlation with age, level of performan …
BACKGROUND: Cervical osteoarthritis (OA) has been documented as a potential source of pain and poor performance in sport horses
Equine Facial Action Coding System for determination of pain-related facial responses in videos of horses.
Rashid M, Silventoinen A, Gleerup KB, Andersen PH. Rashid M, et al. PLoS One. 2020 Nov 3;15(11):e0231608. doi: 10.1371/journal.pone.0231608. eCollection 2020. PLoS One. 2020. PMID: 33141852 Free PMC article.
During the last decade, a number of pain assessment tools based on facial expressions have been developed for horses. ...In particular, chewing (AD81) was found to be indicative of pain. Lastly, we identified increased frequency of half blink (AU47) as a new …
During the last decade, a number of pain assessment tools based on facial expressions have been developed for horses. ...In pa …
Bisphosphonates in veterinary medicine: The new horizon for use.
Suva LJ, Cooper A, Watts AE, Ebetino FH, Price J, Gaddy D. Suva LJ, et al. Bone. 2021 Jan;142:115711. doi: 10.1016/j.bone.2020.115711. Epub 2020 Oct 24. Bone. 2021. PMID: 33141069
Palliative BP treatment has also recently increased in veterinary oncology to alleviate tumor-associated bone pain. In equine veterinary practice, non-nitrogen-containing BPs are FDA-approved to control clinical signs associated with navicular syndrome in adult horses
Palliative BP treatment has also recently increased in veterinary oncology to alleviate tumor-associated bone pain. In equine veterin …
An atypical presentation of a mesenteric Meckel's diverticulum in a 7-year-old warmblood mare: case report.
Stas E, Kranenburg L, Witt P, de Grauw J, van den Brand J, Ensink J, Brommer H. Stas E, et al. BMC Vet Res. 2020 Oct 29;16(1):409. doi: 10.1186/s12917-020-02631-w. BMC Vet Res. 2020. PMID: 33121487 Free PMC article.
BACKGROUND: Meckel's diverticula are a rare cause of small intestinal strangulation, diagnosed at laparotomy or necropsy. ...This case adds to the series of anecdotal reports of anomalies with regard to Meckel's diverticula in the horse....
BACKGROUND: Meckel's diverticula are a rare cause of small intestinal strangulation, diagnosed at laparotomy or necropsy. ...This cas …
In vivo and ex vivo assessment of bladder hyper-permeability and using molecular targeted magnetic resonance imaging to detect claudin-2 in a mouse model for interstitial cystitis.
Smith N, Saunders D, Lerner M, Zalles M, Mamedova N, Cheong D, Mohammadi E, Yuan T, Luo Y, Hurst RE, Greenwood-Van Meerveld B, Towner RA. Smith N, et al. PLoS One. 2020 Oct 23;15(10):e0239282. doi: 10.1371/journal.pone.0239282. eCollection 2020. PLoS One. 2020. PMID: 33095778 Free PMC article.
OBJECTIVES: To determine if the URO-MCP-1 mouse model for bladder IC/BPS is associated with in vivo bladder hyper-permeability, as measured by contrast-enhanced MRI (CE-MRI), and assess whether molecular-targeted MRI (mt-MRI) can visualize in vivo claudin-2 expression as a result …
OBJECTIVES: To determine if the URO-MCP-1 mouse model for bladder IC/BPS is associated with in vivo bladder hyper-permeability, as measured …
Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses.
Grady SE, Lescun TB, Moore GE, Cooper BR, Davern AJ, Brunner TJ, Taylor SD. Grady SE, et al. J Equine Vet Sci. 2020 Nov;94:103204. doi: 10.1016/j.jevs.2020.103204. Epub 2020 Aug 6. J Equine Vet Sci. 2020. PMID: 33077087
The objective was to compare the analgesic efficacy of ketorolac tromethamine (KT) and two other nonsteroidal anti-inflammatory drugs (NSAIDs), including flunixin meglumine (FM) and phenylbutazone (PB), using a heart bar shoe (HBS) model of reversible foot lameness in horses
The objective was to compare the analgesic efficacy of ketorolac tromethamine (KT) and two other nonsteroidal anti-inflammatory drugs (NSAID …
Effects of Flunixin Meglumine, Firocoxib, and Meloxicam in Equines After Castration.
Gobbi FP, Di Filippo PA, Mello LM, Lemos GB, Martins CB, Albernaz AP, Quirino CR. Gobbi FP, et al. J Equine Vet Sci. 2020 Nov;94:103229. doi: 10.1016/j.jevs.2020.103229. Epub 2020 Aug 19. J Equine Vet Sci. 2020. PMID: 33077071
This study is "aimed" to evaluate and compare the efficacy of flunixin meglumine (FM), firocoxib (FX), and meloxicam (MX) after castration of horses. Thirty horses were submitted to open castration and divided into three groups (n = 10) depending on the anti-inflamm …
This study is "aimed" to evaluate and compare the efficacy of flunixin meglumine (FM), firocoxib (FX), and meloxicam (MX) after castration o …
The Effect of Stirrup Iron Style on Normal Forces and Rider Position.
Stapley ED, Stutzman BE, Manfredi JM. Stapley ED, et al. J Equine Vet Sci. 2020 Nov;94:103203. doi: 10.1016/j.jevs.2020.103203. Epub 2020 Aug 4. J Equine Vet Sci. 2020. PMID: 33077067
The stirrup iron has the potential to modify the forces experienced by a horse and rider during ridden exercise. A range of stirrup designs are available, but no previous studies have investigated if these modifications influence riders' position and interaction with the …
The stirrup iron has the potential to modify the forces experienced by a horse and rider during ridden exercise. A range of stirrup d …
Trunk Lateral Flexor Endurance and Body Fat: Predictive Risk Factors for Low Back Pain in Child Equestrian Athletes.
Cejudo A, Ginés-Díaz A, Rodríguez-Ferrán O, Santonja-Medina F, Sainz de Baranda P. Cejudo A, et al. Children (Basel). 2020 Oct 9;7(10):172. doi: 10.3390/children7100172. Children (Basel). 2020. PMID: 33050134 Free PMC article.
Low back pain (LBP) is the most common overuse musculoskeletal injury suffered by child equestrian athletes (CEA). ...Two risk factors and cutoff values were identified as predictors of LBP in CEA: having a high body fat higher than 23% (p = 0.01) and trunk lateral flexor …
Low back pain (LBP) is the most common overuse musculoskeletal injury suffered by child equestrian athletes (CEA). ...Two risk factor …
Multifocal discrete osteolysis in a horse with silicate associated osteoporosis.
Zavodovskaya R, Eckert M, Murphy BG, Stover SM, Kol A, Diab S. Zavodovskaya R, et al. Equine Vet Educ. 2019 Oct;31(10):517-522. doi: 10.1111/eve.12899. Epub 2018 Feb 15. Equine Vet Educ. 2019. PMID: 33041530 Free PMC article.
The horse was evaluated for a 6-months history of progressive back tenderness and acute onset of lameness. The horse had a marked (4/5) [American Association of Equine Practitioners scale] left forelimb lameness, moderate (2/5) hindlimb ataxia and weakness, and cerv …
The horse was evaluated for a 6-months history of progressive back tenderness and acute onset of lameness. The horse had a mar …
Radiographic findings and anatomical variations of the caudal cervical area in horses with neck pain and ataxia: case-control study on 116 horses.
Beccati F, Pepe M, Santinelli I, Gialletti R, Di Meo A, Romero JM. Beccati F, et al. Vet Rec. 2020 Oct 31;187(9):e79. doi: 10.1136/vr.105756. Epub 2020 Oct 8. Vet Rec. 2020. PMID: 33033105
The aim of the study was to investigate the association between AVL-C6 and radiographic findings in the caudal cervical area and between clinical signs of neck pain and ataxia and radiographic findings. METHODS: Medical records of horses subjected to cervical radiog …
The aim of the study was to investigate the association between AVL-C6 and radiographic findings in the caudal cervical area and between cli …
Differential gene expression in skin RNA of horses affected with degenerative suspensory ligament desmitis.
Haythorn A, Young M, Stanton J, Zhang J, Mueller POE, Halper J. Haythorn A, et al. J Orthop Surg Res. 2020 Oct 7;15(1):460. doi: 10.1186/s13018-020-01994-y. J Orthop Surg Res. 2020. PMID: 33028365 Free PMC article.
BACKGROUND: Equine degenerative suspensory ligament desmitis (DSLD) is a systemic connective tissue disorder first identified in Peruvian Paso horses but afflicting other horse breeds as well. Inappropriate accumulation of proteoglycans in connective tissues, most p …
BACKGROUND: Equine degenerative suspensory ligament desmitis (DSLD) is a systemic connective tissue disorder first identified in Peruvian Pa …
Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine.
Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. Shihadih DS, et al. Front Vet Sci. 2020 Aug 26;7:580. doi: 10.3389/fvets.2020.00580. eCollection 2020. Front Vet Sci. 2020. PMID: 33005645 Free PMC article.
The veterinary pharmacopeia available to treat pain and inflammation is limited in number, target of action and efficacy. ...Thus, it was selected for further testing in veterinary clinical trials of pain and inflammation in animals....
The veterinary pharmacopeia available to treat pain and inflammation is limited in number, target of action and efficacy. ...Thus, it …
Geographic Disparities in Clinical Characteristics of Duodenitis-Proximal Jejunitis in Horses in the United States.
Steward SKT, Hassel DM, Martin H, Doddman C, Stewart A, Elzer EJ, Southwood LL. Steward SKT, et al. J Equine Vet Sci. 2020 Oct;93:103192. doi: 10.1016/j.jevs.2020.103192. Epub 2020 Jul 15. J Equine Vet Sci. 2020. PMID: 32972682
Duodenitis-proximal jejunitis (DPJ) is an idiopathic and potentially fatal disease of horses characterized by abdominal pain, proximal intestinal inflammation, and subsequent gastric and small intestinal fluid accumulation. ...This study looked to identify differenc …
Duodenitis-proximal jejunitis (DPJ) is an idiopathic and potentially fatal disease of horses characterized by abdominal pain, …
Effect of Caudal Traction on Mechanical Nociceptive Thresholds of Epaxial and Pelvic Musculature on a Group of Horses With Signs of Back Pain.
Long K, McGowan CM, Hyytiäinen HK. Long K, et al. J Equine Vet Sci. 2020 Oct;93:103197. doi: 10.1016/j.jevs.2020.103197. Epub 2020 Jul 23. J Equine Vet Sci. 2020. PMID: 32972678
Direct muscular attachment from lumbar vertebrae to the caudal vertebrae of the tail suggests that caudal traction, also described as a tail pull, may affect lumbar vertebral segments and/or associated soft tissues in horses. Traction is a commonly used human manual therap …
Direct muscular attachment from lumbar vertebrae to the caudal vertebrae of the tail suggests that caudal traction, also described as a tail …
Mixed methods investigation of the use of telephone triage within UK veterinary practices for horses with abdominal pain: A Participatory action research study.
Lightfoot KL, Burford JH, England GCW, Bowen IM, Freeman SL. Lightfoot KL, et al. PLoS One. 2020 Sep 23;15(9):e0238874. doi: 10.1371/journal.pone.0238874. eCollection 2020. PLoS One. 2020. PMID: 32966300 Free PMC article.
OBJECTIVE: To investigate current approaches to telephone triage of horses with abdominal pain (colic) in veterinary practice and develop new resources to support decision-making. ...METHODS: An online survey assessed current approaches to telephone triage of hor
OBJECTIVE: To investigate current approaches to telephone triage of horses with abdominal pain (colic) in veterinary practice …
Objective Assessment of Acute Pain in Foals Using a Facial Expression-Based Pain Scale.
van Loon J, Verhaar N, van den Berg E, Ross S, de Grauw J. van Loon J, et al. Animals (Basel). 2020 Sep 10;10(9):1610. doi: 10.3390/ani10091610. Animals (Basel). 2020. PMID: 32927590 Free PMC article.
Pain assessment is very important for monitoring welfare and quality of life in horses. ...The aim of the current study was to adapt a facial expression-based pain scale for assessment of acute pain in mature horses for valid pain assessm
Pain assessment is very important for monitoring welfare and quality of life in horses. ...The aim of the current study was to
The effect of anesthetics on toll like receptor 9.
Koutsogiannaki S, Bu W, Hou L, Shibamura-Fujiogi M, Ishida H, Ohto U, Eckenhoff RG, Yuki K. Koutsogiannaki S, et al. FASEB J. 2020 Nov;34(11):14645-14654. doi: 10.1096/fj.202000791RR. Epub 2020 Sep 9. FASEB J. 2020. PMID: 32901993 Free PMC article.
Adaptation strategies of horses with induced forelimb lameness walking on a treadmill.
Serra Bragança FM, Hernlund E, Thomsen MH, Waldern NM, Rhodin M, Byström A, van Weeren PR, Weishaupt MA. Serra Bragança FM, et al. Equine Vet J. 2021 May;53(3):600-611. doi: 10.1111/evj.13344. Epub 2020 Sep 24. Equine Vet J. 2021. PMID: 32888199 Free PMC article.
BACKGROUND: There is a paucity of research describing the gait pattern of lame horses at the walk. OBJECTIVES: To describe the changes in motion pattern and vertical ground reaction forces (GRFz) in horses with induced forelimb lameness at the walk and compare those …
BACKGROUND: There is a paucity of research describing the gait pattern of lame horses at the walk. OBJECTIVES: To describe the change …
Association Between Disease Severity, Heart Rate Variability (HRV) and Serum Cortisol Concentrations in Horses with Acute Abdominal Pain.
Gehlen H, Faust MD, Grzeskowiak RM, Trachsel DS. Gehlen H, et al. Animals (Basel). 2020 Sep 2;10(9):1563. doi: 10.3390/ani10091563. Animals (Basel). 2020. PMID: 32887514 Free PMC article.
Treatment induced a change in the HRV and cortisol response in horses managed conservatively or surgically but not in horses that required euthanasia. However, further studies are required to assess the validity of HRV analyses in horses with colic....
Treatment induced a change in the HRV and cortisol response in horses managed conservatively or surgically but not in horses t …
Remote Controlled Nociceptive Threshold Testing Systems in Large Animals.
Taylor P. Taylor P. Animals (Basel). 2020 Sep 2;10(9):1556. doi: 10.3390/ani10091556. Animals (Basel). 2020. PMID: 32887292 Free PMC article.
Remotely controlled thermal and mechanical NT testing systems were developed to allow free movement during testing and were evaluated in cats, dogs, sheep, horses and camels. Thermal threshold (TT) testing incorporated a heater and temperature sensor held against the anima …
Remotely controlled thermal and mechanical NT testing systems were developed to allow free movement during testing and were evaluated in cat …
A Confirmed Case of Zoonotic Aortitis and Successful Repair with an Allograft.
Gade PV, Witten AJ, Ninad N. Gade PV, et al. EJVES Vasc Forum. 2020 Feb 27;47:26-29. doi: 10.1016/j.ejvsvf.2020.02.004. eCollection 2020. EJVES Vasc Forum. 2020. PMID: 32881989 Free PMC article.
INTRODUCTION: Streptococcus equi subspecies zooepidemicus is a beta-haemolytic group C streptococcus that is a highly contagious infection in horses and other equines. Streptococcus equi infection of the native human aorta is a rare form of aortitis that has a high mortali …
INTRODUCTION: Streptococcus equi subspecies zooepidemicus is a beta-haemolytic group C streptococcus that is a highly contagious infection i …
Effects of Equine-Assisted Therapies or Horse-Riding Simulators on Chronic Pain: A Systematic Review and Meta-Analysis.
Collado-Mateo D, Lavín-Pérez AM, Fuentes García JP, García-Gordillo MÁ, Villafaina S. Collado-Mateo D, et al. Medicina (Kaunas). 2020 Aug 31;56(9):444. doi: 10.3390/medicina56090444. Medicina (Kaunas). 2020. PMID: 32878327 Free PMC article. Review.
Riding a horse may lead to some benefits in chronic pain patients through the improvement of postural control and other biopsychosocial processes. ...Conclusion: Horse riding could be a useful exercise to reduce pain, but more studies are needed to mak …
Riding a horse may lead to some benefits in chronic pain patients through the improvement of postural control and other biopsy …
Mechanical nociceptive assessment of the equine hoof following distal interphalangeal joint intra-articular anesthesia.
Malacarne BD, Cota LO, Neto ACP, Paz CFR, Dias LA, Corrêa MG, Carvalho AM, Faleiros RR, Xavier ABS. Malacarne BD, et al. PeerJ. 2020 Aug 11;8:e9469. doi: 10.7717/peerj.9469. eCollection 2020. PeerJ. 2020. PMID: 32864201 Free PMC article.
BACKGROUND: With the hypothesis that equine dorsal lamellar tissue can be desensitized by anesthesia injection into distal interphalangeal joint (DIPJ), the objective was to assess the mechanical nociceptive threshold of hoof dorsal lamellae following intra-articular (IA) adminis …
BACKGROUND: With the hypothesis that equine dorsal lamellar tissue can be desensitized by anesthesia injection into distal interphalangeal j …
Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report.
Gugliandolo E, Barbagallo A, Peritore AF, Cuzzocrea S, Crupi R. Gugliandolo E, et al. Animals (Basel). 2020 Aug 21;10(9):1469. doi: 10.3390/ani10091469. Animals (Basel). 2020. PMID: 32825646 Free PMC article.
Background: Four show jumping horses were evaluated for non-responsive lameness, which caused their withdrawal from show jumping competitions. ...Although it includes a small number of cases, our study describes for the first time the efficacy of the use of PEA-um in ho
Background: Four show jumping horses were evaluated for non-responsive lameness, which caused their withdrawal from show jumping comp …
Can Endocrine Dysfunction Be Reliably Tested in Aged Horses That Are Experiencing Pain?
Gehlen H, Jaburg N, Merle R, Winter J. Gehlen H, et al. Animals (Basel). 2020 Aug 14;10(8):1426. doi: 10.3390/ani10081426. Animals (Basel). 2020. PMID: 32824027 Free PMC article.
Methods: Fifteen horses with treated low to moderate pain intensities were part of the study. ...Results: There was no significant difference in the basal or stimulated ACTH concentration in horses with pain and controls, between different pain
Methods: Fifteen horses with treated low to moderate pain intensities were part of the study. ...Results: There was no signifi …
Standing Arthroscopic Treatment of Temporomandibular Joint Sepsis in a Horse.
Elzer EJ, Wulster KB, Richardson DW, Ortved KF. Elzer EJ, et al. J Vet Dent. 2020 Jun;37(2):94-99. doi: 10.1177/0898756420948269. Epub 2020 Aug 20. J Vet Dent. 2020. PMID: 32815477
Concurrent otitis media and temporohyoid osteoarthropathy (THO) were also noted. The horse was treated with arthroscopic debridement and lavage during standing sedation followed by local and systemic antimicrobial therapy. There were no complications associated with the su …
Concurrent otitis media and temporohyoid osteoarthropathy (THO) were also noted. The horse was treated with arthroscopic debridement …
Histologic Evaluation of Palmar Digital Nerves after Perineural Injection of 2% Ammonium Chloride in Miniature Horses.
Dau SL, Azevedo MDS, Mazaro RD, de La Corte FD, Fighera R. Dau SL, et al. J Equine Vet Sci. 2020 Sep;92:103171. doi: 10.1016/j.jevs.2020.103171. Epub 2020 Jun 20. J Equine Vet Sci. 2020. PMID: 32797793
The present study aimed to evaluate the neurotoxicity of 2% ammonium chloride (2% AC) applied adjacent to the palmar digital nerves in six miniature horses. The 2% AC and 0.9% saline solution were randomly injected into three and one palmar digital nerve of each horse
The present study aimed to evaluate the neurotoxicity of 2% ammonium chloride (2% AC) applied adjacent to the palmar digital nerves in six m …
Ultrasonography and Surgical Treatment of an Unusual Case of Urethral Calculus in an Arabian Horse.
Abu-Seida AM, Shamaa AA. Abu-Seida AM, et al. J Equine Vet Sci. 2020 Sep;92:103150. doi: 10.1016/j.jevs.2020.103150. Epub 2020 Jun 6. J Equine Vet Sci. 2020. PMID: 32797778
This case report records an obstructive urolithiasis due to a large calcium carbonate urethral stone in an 11-year-old Arabian stallion. The stallion had colicky pain, anuria, and reduction in food and water intakes. Palpation of the penis revealed rhythmic contractions of …
This case report records an obstructive urolithiasis due to a large calcium carbonate urethral stone in an 11-year-old Arabian stallion. The …
Anatomy and Ultrasound-Guided Injection of the Medial Branch of the Dorsal Ramus of the Cervical Spinal Nerves in the Horse: A Cadaveric Study.
Corraretti G, Vandeweerd JM, Hontoir F, Vanderperren K, Palmers K. Corraretti G, et al. Vet Comp Orthop Traumatol. 2020 Nov;33(6):377-386. doi: 10.1055/s-0040-1714301. Epub 2020 Aug 10. Vet Comp Orthop Traumatol. 2020. PMID: 32777844
Our study offers the foundations to develop new diagnostic and therapeutic techniques for pain management in cervical articular process joint arthropathy in horses....
Our study offers the foundations to develop new diagnostic and therapeutic techniques for pain management in cervical articular proce …
Fungal Balls Mimicking Renal Calculi: A Zebra Among Horses.
Das MK, Rangrajan Pakshi R, Kalra S, Elumalai A, Theckumparampil N. Das MK, et al. J Endourol Case Rep. 2019 Dec 2;5(4):167-170. doi: 10.1089/cren.2019.0012. eCollection 2019. J Endourol Case Rep. 2019. PMID: 32775655 Free PMC article.
Case Reports: Our first case is a 48-year-old gentleman with diabetes presented with fever and flank pain. He was found to have bilateral obstructing radiolucent renal calculi with azotemia. ...Our second patient is a 37-year-old lady presented with bilateral flank pain
Case Reports: Our first case is a 48-year-old gentleman with diabetes presented with fever and flank pain. He was found to have bilat …
Venous blood gas parameters, electrolytes, glucose and lactate concentration in sick neonatal foals: Direct venipuncture versus push-pull technique.
Del Prete C, Lanci A, Cocchia N, Freccero F, Di Maio C, Castagnetti C, Mariella J, Micieli F. Del Prete C, et al. Equine Vet J. 2021 May;53(3):488-494. doi: 10.1111/evj.13332. Epub 2020 Sep 3. Equine Vet J. 2021. PMID: 32770680
BACKGROUND: Blood collection by indwelling intravenous catheter (IVC) avoids repeated venipuncture, which could cause thrombophlebitis risk, anxiety and pain in patients. OBJECTIVES: To compare blood gas parameters, electrolytes, glucose, lactate and haematocrit concentrat …
BACKGROUND: Blood collection by indwelling intravenous catheter (IVC) avoids repeated venipuncture, which could cause thrombophlebitis risk, …
Effects of High Intensity Laser Therapy in the Treatment of Tendon and Ligament Injuries in Performance Horses.
Zielińska P, Nicpoń J, Kiełbowicz Z, Soroko M, Dudek K, Zaborski D. Zielińska P, et al. Animals (Basel). 2020 Jul 31;10(8):1327. doi: 10.3390/ani10081327. Animals (Basel). 2020. PMID: 32751968 Free PMC article.
The aim of this study was to evaluate the effects of high intensity laser therapy (HILT) on tendon and ligament injury treatment in horses. Twenty six horses with tendinopathies were randomly assigned to a HILT treated or to a non-treated group. Each horse wa …
The aim of this study was to evaluate the effects of high intensity laser therapy (HILT) on tendon and ligament injury treatment in horse
Serotonin-evoked cytosolic Ca(2+) release and opioid receptor expression are upregulated in articular cartilage chondrocytes from osteoarthritic joints in horses.
Skiöldebrand E, Ley C, Björklund U, Lindahl A, Hansson E. Skiöldebrand E, et al. Vet Anim Sci. 2019 Sep 27;8:100078. doi: 10.1016/j.vas.2019.100078. eCollection 2019 Dec. Vet Anim Sci. 2019. PMID: 32734095 Free PMC article.
Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular cartilage could represent novel therapeutic targets. ...We show that chondrocytes in different inflammatory stages react differently to the n …
Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular c …
Analysis of Thoroughbred horse farm workers' compensation insurance claims in Kentucky: Injury frequency, cost, lost time, and associated occupational factors.
Flunker JC, Clouser JM, Swanberg JE. Flunker JC, et al. Am J Ind Med. 2020 Oct;63(10):936-948. doi: 10.1002/ajim.23159. Epub 2020 Jul 28. Am J Ind Med. 2020. PMID: 32725660
BACKGROUND: Thoroughbred horse farm workers self-report a high frequency of work-related injuries and pain. ...CONCLUSIONS: Our findings elucidate factors to reduce injury frequency, cost, and lost time among Thoroughbred horse farm workers....
BACKGROUND: Thoroughbred horse farm workers self-report a high frequency of work-related injuries and pain. ...CONCLUSIONS: Ou …
Indicators of 'critical' outcomes in 941 horses seen 'out-of-hours' for colic.
Bowden A, England GCW, Brennan ML, Mair TS, Furness WA, Freeman SL, Burford JH. Bowden A, et al. Vet Rec. 2020 Dec 19;187(12):492. doi: 10.1136/vr.105881. Epub 2020 Jul 27. Vet Rec. 2020. PMID: 32719081
BACKGROUND: This study aimed to describe the presentation and outcomes of horses with signs of colic (abdominal pain) seen 'out-of-hours' in equine practice. ...The 'red flag' parameters identified should be considered an essential component of the primary assessmen …
BACKGROUND: This study aimed to describe the presentation and outcomes of horses with signs of colic (abdominal pain) seen 'ou …
Varicose veins and occupational health: symptoms, treatment and prevention.
de Lima DC. de Lima DC. Rev Bras Med Trab. 2019 Dec 1;17(4):589-593. doi: 10.5327/Z1679443520190460. eCollection 2019. Rev Bras Med Trab. 2019. PMID: 32685759 Free PMC article.
The aim of the present study was to perform a literature review about the symptoms, treatment and prevention of varicose veins (VV) within the occupational medicine setting. I reviewed scientific articles, books, master's and doctoral dissertations and synthesized the resu …
The aim of the present study was to perform a literature review about the symptoms, treatment and prevention of varicose veins (VV) within t …
Antinociceptive Effect of Intravenous Regional Analgesia in Horses Underwent Selected Short-Time Distal Limb Surgeries.
Samy A, Elmetwally M, El-Khodery SA. Samy A, et al. J Equine Vet Sci. 2020 Aug;91:103113. doi: 10.1016/j.jevs.2020.103113. Epub 2020 May 6. J Equine Vet Sci. 2020. PMID: 32684258
Six clinically healthy horses were selected randomly for establishing the doses of lidocaine Hcl and mepivacaine in IVRA in horse limbs. ...Postoperative pain was measured using both Horse Grimace Pain Scale and multifactorial numerical rating c …
Six clinically healthy horses were selected randomly for establishing the doses of lidocaine Hcl and mepivacaine in IVRA in horse
Husbandry, Use, and Orthopedic Health of Horses Owned by Competitive and Leisure Riders in Switzerland.
Dittmann MT, Latif SN, Hefti R, Hartnack S, Hungerbühler V, Weishaupt MA. Dittmann MT, et al. J Equine Vet Sci. 2020 Aug;91:103107. doi: 10.1016/j.jevs.2020.103107. Epub 2020 Apr 27. J Equine Vet Sci. 2020. PMID: 32684252
A total of 237 owners completed an online survey providing information on their athletic ambitions, their horse's husbandry, health, training, and tack. Two experienced veterinarians assessed gait irregularities, muscular development, and back pain in the …
A total of 237 owners completed an online survey providing information on their athletic ambitions, their horse's husbandry, h …
Identification of monoclonal antibodies suitable for blocking IGF-1 receptors in the horse.
Rahnama S, Vathsangam N, Spence R, Anderson ST, de Laat MA, Bailey S, Sillence MN. Rahnama S, et al. Domest Anim Endocrinol. 2021 Jan;74:106510. doi: 10.1016/j.domaniend.2020.106510. Epub 2020 Jun 17. Domest Anim Endocrinol. 2021. PMID: 32652390
Prolonged hyperinsulinemia is thought to be the cause of equine endocrinopathic laminitis, a common and crippling disease of the foot, for which there are no pharmacologic treatments other than pain relief. It has been suggested that insulin causes its effects on the lamel …
Prolonged hyperinsulinemia is thought to be the cause of equine endocrinopathic laminitis, a common and crippling disease of the foot, for w …
Periprosthetic Joint Infection with Listeria monocytogenes: A Case Report.
Paziuk T, Levicoff E, Tan T, Good R. Paziuk T, et al. JBJS Case Connect. 2020 Apr-Jun;10(2):e1900489. doi: 10.2106/JBJS.CC.19.00489. JBJS Case Connect. 2020. PMID: 32649150
CASE: A 67-year-old immunocompromised woman presented with 2 weeks of atraumatic knee pain 4 months after a primary total knee arthroplasty. The patient had a history of consuming unpasteurized dairy products and horse rearing. ...
CASE: A 67-year-old immunocompromised woman presented with 2 weeks of atraumatic knee pain 4 months after a primary total knee arthro …
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm.
Garvin MR, Alvarez C, Miller JI, Prates ET, Walker AM, Amos BK, Mast AE, Justice A, Aronow B, Jacobson D. Garvin MR, et al. Elife. 2020 Jul 7;9:e59177. doi: 10.7554/eLife.59177. Elife. 2020. PMID: 32633718 Free PMC article.
However, some individuals develop much more severe, life-threatening symptoms affecting the lungs and other parts of the body including the heart and brain. SARS-CoV-2 uses a human enzyme called ACE2 like a 'Trojan Horse' to sneak into the cells of its host. ACE2 lowers bl …
However, some individuals develop much more severe, life-threatening symptoms affecting the lungs and other parts of the body including the …
Prioritisation of animal welfare issues in the UK using expert consensus.
Rioja-Lang F, Bacon H, Connor M, Dwyer CM. Rioja-Lang F, et al. Vet Rec. 2020 Dec 19;187(12):490. doi: 10.1136/vr.105964. Epub 2020 Jul 5. Vet Rec. 2020. PMID: 32631849 Free PMC article.
RESULTS: A comprehensive list of welfare issues was generated for each species by discussion boards (cats, rabbits and horses) or by literature review (dogs, pigs, poultry, cattle and small ruminants). ...In the final stage, during the workshop, the top-ranking welfare iss …
RESULTS: A comprehensive list of welfare issues was generated for each species by discussion boards (cats, rabbits and horses) or by …
An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization.
Bertoni L, Jacquet-Guibon S, Branly T, Legendre F, Desancé M, Mespoulhes C, Melin M, Hartmann DJ, Schmutz A, Denoix JM, Galéra P, Demoor M, Audigié F. Bertoni L, et al. PLoS One. 2020 Jun 25;15(6):e0235251. doi: 10.1371/journal.pone.0235251. eCollection 2020. PLoS One. 2020. PMID: 32584901 Free PMC article.
Osteoarthritis is a common cause of pain and economic loss in both humans and horses. The horse is recognized as a suitable model for human osteoarthritis, because the thickness, structure, and mechanical properties of equine articular cartilage are highly co …
Osteoarthritis is a common cause of pain and economic loss in both humans and horses. The horse is recognized as a suit …
Application of a Ridden Horse Pain Ethogram and Its Relationship with Gait in a Convenience Sample of 60 Riding Horses.
Dyson S, Pollard D. Dyson S, et al. Animals (Basel). 2020 Jun 17;10(6):1044. doi: 10.3390/ani10061044. Animals (Basel). 2020. PMID: 32560486 Free PMC article.
A Ridden Horse Pain Ethogram (RHpE) comprising 24 behaviours has been developed to facilitate the identification of musculoskeletal pain. ...Ridden Horse Pain Ethogram scores ranged from 3 to 16/24 (median 9); rider skill score ranged from 2.5 t …
A Ridden Horse Pain Ethogram (RHpE) comprising 24 behaviours has been developed to facilitate the identification of musculoske …
Myelopathy and Reactive Microgliosis and Astrogliosis in Equine Back Pain.
Mayaki AM, Abdul Razak IS, Mohd Adzahan N, Mazlan M, Abdullah R. Mayaki AM, et al. J Equine Vet Sci. 2020 Jul;90:103019. doi: 10.1016/j.jevs.2020.103019. Epub 2020 Apr 9. J Equine Vet Sci. 2020. PMID: 32534783
Equine chronic back pain (CBP) has been linked to different pathologic processes, which directly or indirectly involve spinal structures. ...This study described the spinal cord lesions and the development of reactive microgliosis and astrocytosis in the spinal cords of …
Equine chronic back pain (CBP) has been linked to different pathologic processes, which directly or indirectly involve spinal structu …
Ultrasound-Guided Transversus Abdominis Plane Block in Shetland Ponies: A Description of a Three-Point Injection Technique and Evaluation of Potential Analgesic Effects.
Küls N, Trujanovic R, Otero PE, Larenza-Menzies MP. Küls N, et al. J Equine Vet Sci. 2020 Jul;90:102994. doi: 10.1016/j.jevs.2020.102994. Epub 2020 Mar 30. J Equine Vet Sci. 2020. PMID: 32534772
Colic surgery is one of the most painful procedures carried out in horses. Common strategies to alleviate immediate postsurgical abdominal pain include the administration of potent systemic analgesics; however, these may cause unwanted adverse effects such as cardio …
Colic surgery is one of the most painful procedures carried out in horses. Common strategies to alleviate immediate postsurgical abdo …
Using Artificial Intelligence to Predict Survivability Likelihood and Need for Surgery in Horses Presented With Acute Abdomen (Colic).
Fraiwan MA, Abutarbush SM. Fraiwan MA, et al. J Equine Vet Sci. 2020 Jul;90:102973. doi: 10.1016/j.jevs.2020.102973. Epub 2020 Mar 19. J Equine Vet Sci. 2020. PMID: 32534764
Those were the need for surgical intervention and survivability likelihood of affected horses based on clinical data (history, clinical examination findings, and diagnostic procedures). ...The machine learning algorithms were able to predict the need for surgery and surviv …
Those were the need for surgical intervention and survivability likelihood of affected horses based on clinical data (history, clinic …
Post-operative pain behaviour associated with surgical castration in donkeys (Equus asinus).
de Oliveira MGC, Luna SPL, Nunes TL, Firmino PR, de Lima AGA, Ferreira J, Trindade PHE, Júnior RAB, de Paula VV. de Oliveira MGC, et al. Equine Vet J. 2021 Mar;53(2):261-266. doi: 10.1111/evj.13306. Epub 2020 Jul 8. Equine Vet J. 2021. PMID: 32525236 Free PMC article.
BACKGROUND: Recognising pain in donkeys is challenging because they are stoic. OBJECTIVES: To identify the responses of donkeys before and after surgical pain. ...Tail, head and ear movements are unspecific responses related both to pain and a dirty stall, an …
BACKGROUND: Recognising pain in donkeys is challenging because they are stoic. OBJECTIVES: To identify the responses of donkeys befor …
Localisation of cannabinoid and cannabinoid-related receptors in the equine dorsal root ganglia.
Chiocchetti R, Rinnovati R, Tagliavia C, Stanzani A, Galiazzo G, Giancola F, Silva M, Capodanno Y, Spadari A. Chiocchetti R, et al. Equine Vet J. 2021 May;53(3):549-557. doi: 10.1111/evj.13305. Epub 2020 Jul 4. Equine Vet J. 2021. PMID: 32524649
BACKGROUND: Growing evidence recognises cannabinoid receptors as potential therapeutic targets for pain. Consequently, there is increasing interest in developing cannabinoid receptor agonists for treating pain. ...These findings could be of particular relevance for …
BACKGROUND: Growing evidence recognises cannabinoid receptors as potential therapeutic targets for pain. Consequently, there is incre …
Chondrosesamoidean ligament enthesopathy: Prevalence and findings in a population of lame horses imaged with positron emission tomography.
Norvall A, Spriet M, Espinosa P, Ariño-Estrada G, Murphy BG, Katzman SA, Galuppo LD. Norvall A, et al. Equine Vet J. 2021 May;53(3):451-459. doi: 10.1111/evj.13299. Epub 2020 Jun 29. Equine Vet J. 2021. PMID: 32491220
CONCLUSIONS: PET led to identification of ChSL enthesopathy in a large proportion of horses with foot pain. This finding is most commonly associated with other lesions but may also represent the main abnormality. ...ChSL enthesopathy may be an important but previous …
CONCLUSIONS: PET led to identification of ChSL enthesopathy in a large proportion of horses with foot pain. This finding is mo …
Cervical Epidural and Subarachnoid Catheter Placement in Standing Adult Horses.
Hurcombe SD, Morris TB, VanderBroek AR, Habecker P, Wulster K, Hopster K. Hurcombe SD, et al. Front Vet Sci. 2020 May 14;7:232. doi: 10.3389/fvets.2020.00232. eCollection 2020. Front Vet Sci. 2020. PMID: 32478105 Free PMC article.
CSF cytology was assessed up to every 24 h for the study period. Horses were assessed daily for signs of discomfort, neck pain, catheter insertion site swelling, or changes in behavior. A complete postmortem assessment of the spinal tissues was performed at the end …
CSF cytology was assessed up to every 24 h for the study period. Horses were assessed daily for signs of discomfort, neck pain
Is the T-ligament a ligament? A histological study in equine cadaver forelimbs.
Hontoir F, Paques F, Simon V, Balau B, Nicaise C, Clegg P, Dugdale A, Vandeweerd JM. Hontoir F, et al. Res Vet Sci. 2020 Oct;132:10-16. doi: 10.1016/j.rvsc.2020.05.018. Epub 2020 May 23. Res Vet Sci. 2020. PMID: 32470846
Foot pain is a frequent cause of lameness in horses and can involve multiple structures within the hoof. ...Blood vessels were identified in the T-ligament and were penetrating the deep digital flexor tendon (8/10 limbs, 5/5 horses). In conclusion, the T-liga …
Foot pain is a frequent cause of lameness in horses and can involve multiple structures within the hoof. ...Blood vessels were …
Effectiveness of a paraverterbral nerve block versus local portal blocks for laparoscopic closure of the nephrosplenic space: A pilot study.
Delli-Rocili MM, Cribb NC, Trout DR, Thomason JJ, Valverde A. Delli-Rocili MM, et al. Vet Surg. 2020 Jul;49(5):1007-1014. doi: 10.1111/vsu.13452. Epub 2020 May 28. Vet Surg. 2020. PMID: 32463519
OBJECTIVE: To compare the effectiveness of a paravertebral nerve block vs local portal blocks for laparoscopic closure of the nephrosplenic space in standing sedated research horses. STUDY DESIGN: Randomized clinical trial. ANIMALS: Twelve horses were randomly alloc …
OBJECTIVE: To compare the effectiveness of a paravertebral nerve block vs local portal blocks for laparoscopic closure of the nephrosplenic …
Quantification and validation of nine nonsteroidal anti-inflammatory drugs in equine urine using gas chromatography-mass spectrometry for doping control.
Göktaş EF, Kabil E, Arıöz F. Göktaş EF, et al. Drug Test Anal. 2020 Aug;12(8):1065-1077. doi: 10.1002/dta.2864. Epub 2020 Jun 28. Drug Test Anal. 2020. PMID: 32449838
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in therapeutic doses in human and veterinary medicine for the treatment of inflammation, pain, and fever. A method for the simultaneous determination of nine NSAIDs, known as therapeutic prohibited substances, …
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in therapeutic doses in human and veterinary medicine for the treatment of i …
Determination of grapiprant plasma and urine concentrations in horses.
Cox S, Sommardahl C, Fortner C, Davis R, Bergman J, Doherty T. Cox S, et al. Vet Anaesth Analg. 2020 Sep;47(5):705-709. doi: 10.1016/j.vaa.2020.04.006. Epub 2020 Apr 25. Vet Anaesth Analg. 2020. PMID: 32439238
Concentrations were below the lower limit of quantification (50 ng mL(-1)) in four of six horses at 1 hour and in all six horses by 2 hours after drug administration. ...CONCLUSIONS AND CLINICAL RELEVANCE: Currently, there are no published studies looking at the pha …
Concentrations were below the lower limit of quantification (50 ng mL(-1)) in four of six horses at 1 hour and in all six horses
Does Thirty-Minute Standardised Training Improve the Inter-Observer Reliability of the Horse Grimace Scale (HGS)? A Case Study.
Dai F, Leach M, MacRae AM, Minero M, Costa ED. Dai F, et al. Animals (Basel). 2020 Apr 30;10(5):781. doi: 10.3390/ani10050781. Animals (Basel). 2020. PMID: 32365927 Free PMC article.
The Horse Grimace Scale (HGS) is a facial-expression-based pain coding system that enables a range of acute painful conditions in horses to be effectively identified. Using valid assessment methods to identify pain in horses is of a clear import …
The Horse Grimace Scale (HGS) is a facial-expression-based pain coding system that enables a range of acute painful conditions …
Full-length genomic sequencing and characterization of Borna disease virus 1 isolates: Lessons in epidemiology.
Guo Y, He P, Sun L, Zhang X, Xu X, Tang T, Zhou W, Li Q, Zou D, Bode L, Xie P. Guo Y, et al. J Med Virol. 2020 Apr 28. doi: 10.1002/jmv.25951. Online ahead of print. J Med Virol. 2020. PMID: 32343416
They were compared with 20 genomes and 20 single-gene sequences (N and P) of worldwide human strains from psychiatric and neurologic patients and animal strains from horses with Borna disease available at GenBank. Phylogenetic analyses confirmed a low divergence not exceed …
They were compared with 20 genomes and 20 single-gene sequences (N and P) of worldwide human strains from psychiatric and neurologic patient …
Misdiagnosis in the COVID-19 Era: When Zebras Are Everywhere, Don't Forget the Horses.
Yousefzai R, Bhimaraj A. Yousefzai R, et al. JACC Case Rep. 2020 Aug;2(10):1614-1619. doi: 10.1016/j.jaccas.2020.04.018. Epub 2020 Apr 27. JACC Case Rep. 2020. PMID: 32342051 Free PMC article.
We describe a patient who presented with respiratory failure, chest pain, and fever. In the COVID-19 pandemic era, the focus was diverted to the coronavirus infection, and ST-segment elevation myocardial infarction was missed. ...
We describe a patient who presented with respiratory failure, chest pain, and fever. In the COVID-19 pandemic era, the focus was dive …
Pharmacokinetic study of oral amitriptyline in horses.
Recchi L, Alvariza S, Benech A, Ruiz N, José Estradé M, Suarez G, Crosignani N. Recchi L, et al. J Vet Pharmacol Ther. 2020 Jul;43(4):381-384. doi: 10.1111/jvp.12870. Epub 2020 Apr 27. J Vet Pharmacol Ther. 2020. PMID: 32339314
The purpose of this study was to evaluate the pharmacokinetics of oral amitriptyline in horses. Oral amitriptyline (1 mg/kg) was administered to six horses. ...
The purpose of this study was to evaluate the pharmacokinetics of oral amitriptyline in horses. Oral amitriptyline (1 mg/kg) was admi …
Tranquilizer effect on the Lyapunov exponents of lame horses.
Zhao J, Marghitu DB, Schumacher J. Zhao J, et al. Heliyon. 2020 Apr 8;6(4):e03726. doi: 10.1016/j.heliyon.2020.e03726. eCollection 2020 Apr. Heliyon. 2020. PMID: 32322720 Free PMC article.
Some equine clinicians believe that tranquilization with acepromazine will make lameness more evident by causing the horse to focus on adjusting its gait to avoid limb pain rather than its surroundings. ...The nonlinear dynamic methods can be used to analyze the gai …
Some equine clinicians believe that tranquilization with acepromazine will make lameness more evident by causing the horse to focus o …
Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals.
Gencoglu H, Orhan C, Sahin E, Sahin K. Gencoglu H, et al. Animals (Basel). 2020 Apr 17;10(4):697. doi: 10.3390/ani10040697. Animals (Basel). 2020. PMID: 32316397 Free PMC article. Review.
OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, has specific connective tissue types for skin, bones, reticulate, basal lamina, bones, cell surfaces, while type II collagen (UC-II) forms th …
OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, h …
Synthesis of stable isotope-labelled firocoxib.
Latli B, Gao A, Kvaternick V, Tecle B, Pennino S, Yee NK, Song J. Latli B, et al. J Labelled Comp Radiopharm. 2020 Jun 30;63(8):386-392. doi: 10.1002/jlcr.3842. Epub 2020 May 5. J Labelled Comp Radiopharm. 2020. PMID: 32307719
Firocoxib (ML-1,785,713) is a nonsteroidal, potent, and selective COX-2 inhibitor, approved for the control of pain and inflammation associated with osteoarthritis in dogs and horses, as well as to control postoperative pain and inflammation in dogs. ...The s …
Firocoxib (ML-1,785,713) is a nonsteroidal, potent, and selective COX-2 inhibitor, approved for the control of pain and inflammation …
Quantitative sensory testing of the equine face.
Veres-Nyéki KO, Nyéki J, Bodó G, Spadavecchia C. Veres-Nyéki KO, et al. Equine Vet J. 2021 Jan;53(1):177-185. doi: 10.1111/evj.13270. Epub 2020 May 12. Equine Vet J. 2021. PMID: 32306423 Free article.
STUDY DESIGN: Method description. METHODS: Thirty-four healthy Warmblood horses were used in the study. Six (tactile sensory threshold) and five (mechanical nociceptive and thermal nociceptive thresholds) areas of the left side of the face with clear anatomical landmarks w …
STUDY DESIGN: Method description. METHODS: Thirty-four healthy Warmblood horses were used in the study. Six (tactile sensory threshol …
Detection and Pharmacokinetics of Etoricoxib in Thoroughbred Horses.
Subhahar MB, Singh J, Albert PH, Kadry AM. Subhahar MB, et al. J Equine Vet Sci. 2020 May;88:102942. doi: 10.1016/j.jevs.2020.102942. Epub 2020 Feb 1. J Equine Vet Sci. 2020. PMID: 32303303
Etoricoxib, a selective inhibitor of cyclooxygenase-2, is used in the treatment of many inflammatory diseases and dental pain in humans. The aim of this study was to determine the pharmacokinetics and metabolism of etoricoxib in horses. Six horses weighing an …
Etoricoxib, a selective inhibitor of cyclooxygenase-2, is used in the treatment of many inflammatory diseases and dental pain in huma …
Critical Evaluation of Whole-Body Cryostimulation Protocol in Race Horses.
Bogard F, Bouchet B, Murer S, Filliard JR, Beaumont F, Polidori G. Bogard F, et al. J Equine Vet Sci. 2020 May;88:102944. doi: 10.1016/j.jevs.2020.102944. Epub 2020 Feb 4. J Equine Vet Sci. 2020. PMID: 32303300
With this new concept of WBC, the protocol usually utilized for relieving pain and discomfort in humans has been extended to horses. The investigations described herein focus on the reduction of horse skin temperature when applying human WBC protocols. Based …
With this new concept of WBC, the protocol usually utilized for relieving pain and discomfort in humans has been extended to horse
Desensitisation of the distal forelimb following intrathecal anaesthesia of the carpal sheath in horses.
Miagkoff L, Bonilla AG. Miagkoff L, et al. Equine Vet J. 2021 Jan;53(1):167-176. doi: 10.1111/evj.13269. Epub 2020 May 26. Equine Vet J. 2021. PMID: 32301518
Anaesthetic injection was not smooth in the 2 horses without desensitisation. Desensitisation started between 30 and 60 minutes in 67% of desensitised heel bulbs (8/12), and 50% (6/12) of them were still completely desensitised at 180 minutes. ...MAIN LIMITATIONS: Skin mec …
Anaesthetic injection was not smooth in the 2 horses without desensitisation. Desensitisation started between 30 and 60 minutes in 67 …
Proteinase Activated Receptor 4 in the Jejunum of Healthy Horses and of Horses With Epiploic Hernia.
Lambertini C, Bombardi C, Zannoni A, Bernardini C, Dondi F, Morini M, Rinnovati R, Spadari A, Romagnoli N. Lambertini C, et al. Front Vet Sci. 2020 Mar 31;7:158. doi: 10.3389/fvets.2020.00158. eCollection 2020. Front Vet Sci. 2020. PMID: 32296721 Free PMC article.
Proteinase activated receptor 4 (PAR(4)) in the gastrointestinal tract is involved in the regulation of inflammation and pain pathways. The aim of the present study was to evaluate the distribution and expression of PAR(4) in the jejunum of healthy horses and in the …
Proteinase activated receptor 4 (PAR(4)) in the gastrointestinal tract is involved in the regulation of inflammation and pain pathway …
A Radiographic Technique for Assessment of Morphologic Variations of the Equine Caudal Cervical Spine.
Gee C, Small A, Shorter K, Brown WY. Gee C, et al. Animals (Basel). 2020 Apr 12;10(4):667. doi: 10.3390/ani10040667. Animals (Basel). 2020. PMID: 32290538 Free PMC article.
Whereas the prevalence of ECCMV is not known, it has been recognized for many years and has been reported to occur with relatively high frequency within multiple populations of domesticated horses. To date, there is no documented link between the occurrence of ECCMV and cl …
Whereas the prevalence of ECCMV is not known, it has been recognized for many years and has been reported to occur with relatively high freq …
Determining a Welfare Prioritization for Horses Using a Delphi Method.
Rioja-Lang FC, Connor M, Bacon H, Dwyer CM. Rioja-Lang FC, et al. Animals (Basel). 2020 Apr 9;10(4):647. doi: 10.3390/ani10040647. Animals (Basel). 2020. PMID: 32283607 Free PMC article.
The issues considered to cause greatest suffering for individual horses were delayed euthanasia, lack of recognition by owners of pain behaviour, large worm burdens, obesity and being fed unsuitable diets for equine feeding behaviour. These outcomes can help to focu …
The issues considered to cause greatest suffering for individual horses were delayed euthanasia, lack of recognition by owners of …
Ultrasound-guided continuous block of median and ulnar nerves in horses: development of the technique.
Souto MTM, Fantoni DT, Hamaji A, Hamaji M, Vendruscolo CP, Otsuki DA, Pinto ACB, Ambrósio AM. Souto MTM, et al. Vet Anaesth Analg. 2020 May;47(3):405-413. doi: 10.1016/j.vaa.2019.12.008. Epub 2020 Feb 6. Vet Anaesth Analg. 2020. PMID: 32249126
ANIMALS: A total of 16 thoracic limbs from horse cadavers and 18 adult horses. METHOD: This study was conducted in three phases. ...Phase 3: Two case reports of horses with chronic pain of different etiologies. Catheters were inserted between the epine …
ANIMALS: A total of 16 thoracic limbs from horse cadavers and 18 adult horses. METHOD: This study was conducted in three phase …
Extraction of α-neurotoxins from equine plasma by receptor based affinity purification.
Timms M, Ganio K, Steel R. Timms M, et al. Drug Test Anal. 2020 Jul;12(7):918-928. doi: 10.1002/dta.2797. Epub 2020 Apr 13. Drug Test Anal. 2020. PMID: 32246898
As an example of this, cobratoxin, an alpha-neurotoxin found in cobra venom, is claimed to be an effective treatment for pain. Recent analysis of seized samples identified venom from two different species of snake. ...Cobratoxin, conotoxins, and bungarotoxins (a component …
As an example of this, cobratoxin, an alpha-neurotoxin found in cobra venom, is claimed to be an effective treatment for pain. Recent …
[Analgesic effect of Fengshi Qutong Capsules on mice with chronic inflammatory pain caused by complete Freund's adjuvant].
Liu CF, Wang JX, Li YQ, Wang C, Zhu CY, Wang JX, Jia KX, Jing Y, Miao YD, Lin N. Liu CF, et al. Zhongguo Zhong Yao Za Zhi. 2020 Feb;45(4):916-922. doi: 10.19540/j.cnki.cjcmm.20191105.401. Zhongguo Zhong Yao Za Zhi. 2020. PMID: 32237494 Chinese.
A model of chronic inflammatory pain was induced in mice by complete Freund's adjuvant(CFA). The mice were divided into normal control group, model group, model+FSQTC 0.3, 0.6 and 1.2 gkg~(-1 )groups, model+positive control drug ibuprofen(IBP, 0.34 mgkg~(-1)d~(-1)) …
A model of chronic inflammatory pain was induced in mice by complete Freund's adjuvant(CFA). The mice were divided into normal …
Mouth Pain in Horses: Physiological Foundations, Behavioural Indices, Welfare Implications, and a Suggested Solution.
Mellor DJ. Mellor DJ. Animals (Basel). 2020 Mar 29;10(4):572. doi: 10.3390/ani10040572. Animals (Basel). 2020. PMID: 32235343 Free PMC article. Review.
A proposition addressed here is that, although bitted horses are viewed by many equestrians as being largely free of bit-related mouth pain, it seems likely that most behavioural signs of such pain are simply not recognised. ...Mouth pain in horses
A proposition addressed here is that, although bitted horses are viewed by many equestrians as being largely free of bit-related mout …
Identification and Quantification of Transient Receptor Potential Vanilloid 1 (TRPV1) in Equine Articular Tissue.
Braucke AFGV, Frederiksen NL, Berg LC, Aarsvold S, Müller FC, Boesen MP, Lindegaard C. Braucke AFGV, et al. Animals (Basel). 2020 Mar 18;10(3):506. doi: 10.3390/ani10030506. Animals (Basel). 2020. PMID: 32197454 Free PMC article.
Joint pain and osteoarthritis (OA) are some of the most common causes of lameness in horses, and most of the available treatments focus on symptomatic relief without a disease-modifying effect. ...Future studies will determine the clinical potential of equine TRPV1 …
Joint pain and osteoarthritis (OA) are some of the most common causes of lameness in horses, and most of the available treatme …
Induction of Noninflammatory Pain in an Experimental Foot Lameness Model in Horses.
Brunner TJ, Lescun TB, Moore GE, Grady SE, Davern AJ, Taylor SD. Brunner TJ, et al. J Equine Vet Sci. 2020 Apr;87:102925. doi: 10.1016/j.jevs.2020.102925. Epub 2020 Jan 11. J Equine Vet Sci. 2020. PMID: 32172915
The purpose of this study was to determine if this HBS model of lameness induces inflammation in horses. Five healthy adult horses from a university teaching herd were enrolled. ...In conclusion, the HBS model did not induce inflammation as assessed by select inflam …
The purpose of this study was to determine if this HBS model of lameness induces inflammation in horses. Five healthy adult horses
Pharmacopuncture Analgesia Using Flunixin Meglumine Injection into the Acupoint GV1 (Ho Hai) After Elective Castration in Horses.
Reginato GM, Xavier NV, Alonso BB, Lima DP, Pereira Sirqueira TC, Carregaro AB. Reginato GM, et al. J Equine Vet Sci. 2020 Apr;87:102911. doi: 10.1016/j.jevs.2020.102911. Epub 2020 Jan 7. J Equine Vet Sci. 2020. PMID: 32172910
The study evaluated the effect of a 1/10 dose of flunixin meglumine administered into the governing vessel 1 (GV1) acupoint in horses that underwent castration. Twenty animals received 0.02 mg/kg detomidine intravenously, followed by 2.2 mg/kg ketamine and 0.1 mg/kg diazep …
The study evaluated the effect of a 1/10 dose of flunixin meglumine administered into the governing vessel 1 (GV1) acupoint in horses
Clinical findings, diagnoses, and outcomes of horses presented for colic to a referral hospital in Atlantic Canada (2000-2015).
Kaufman JM, Nekouei O, Doyle AJ, Biermann NM. Kaufman JM, et al. Can Vet J. 2020 Mar;61(3):281-288. Can Vet J. 2020. PMID: 32165752 Free PMC article.
Medical records of equine patients presented for signs of abdominal pain to the Atlantic Veterinary College Teaching Hospital between 2000 and 2015 were reviewed. ...Overall survival to discharge was 69%. The survival rates for horses were 82.9% for those with no di …
Medical records of equine patients presented for signs of abdominal pain to the Atlantic Veterinary College Teaching Hospital between …
Standing MRI lesions of the distal interphalangeal joint and podotrochlear apparatus occur with a high frequency in warmblood horses.
Gutierrez-Nibeyro SD, Werpy NM, Gold SJ, Olguin S, Schaeffer DJ. Gutierrez-Nibeyro SD, et al. Vet Radiol Ultrasound. 2020 May;61(3):336-345. doi: 10.1111/vru.12855. Epub 2020 Mar 11. Vet Radiol Ultrasound. 2020. PMID: 32162431
Foot pain is a common presenting complaint in Warmblood horses. The aim of this retrospective, cross-sectional study was to determine the spectrum of foot lesions detected by magnetic resonance imaging (MRI) in Warmblood horses used for dressage, jumping, and …
Foot pain is a common presenting complaint in Warmblood horses. The aim of this retrospective, cross-sectional study was to de …
Horses as a Crucial Part of One Health.
Lönker NS, Fechner K, Wahed AAE. Lönker NS, et al. Vet Sci. 2020 Feb 29;7(1):28. doi: 10.3390/vetsci7010028. Vet Sci. 2020. PMID: 32121327 Free PMC article. Review.
The long history of the relationship between horses and humans is shaped by the service of horses in wars or even in mines. ...Horses are of relevance in the spillover of zoonotic and emerging diseases from wildlife to human (e.g., Hendra Virus), and in non-c …
The long history of the relationship between horses and humans is shaped by the service of horses in wars or even in mines. .. …
Incisional infections associated with ventral midline celiotomy in horses.
Shearer TR, Holcombe SJ, Valberg SJ. Shearer TR, et al. J Vet Emerg Crit Care (San Antonio). 2020 Mar;30(2):136-148. doi: 10.1111/vec.12936. Epub 2020 Feb 25. J Vet Emerg Crit Care (San Antonio). 2020. PMID: 32100465 Review.
Factors associated with the patient, surgical lesion and procedures, anesthesia, and recovery put the horse at risk for surgical site infection. Infection is the most important risk factor for incisional hernia formation. ...Limiting risk factors for surgical site infectio …
Factors associated with the patient, surgical lesion and procedures, anesthesia, and recovery put the horse at risk for surgical site …
Intratesticular mepivacaine versus lidocaine in anaesthetised horses undergoing Henderson castration.
Crandall A, Hopster K, Grove A, Levine D. Crandall A, et al. Equine Vet J. 2020 Nov;52(6):805-810. doi: 10.1111/evj.13250. Epub 2020 Mar 23. Equine Vet J. 2020. PMID: 32090383
BACKGROUND: In horses undergoing castration, direct comparison of intratesticular lidocaine vs mepivacaine as analgesic adjuncts has not yet been analysed. ...The average cremaster relaxation score on both testicles treated with mepivacaine was 1 compared to the lidocaine …
BACKGROUND: In horses undergoing castration, direct comparison of intratesticular lidocaine vs mepivacaine as analgesic adjuncts has …
Mycotic Abdominal Aortic and Iliac Aneurysm Caused by Streptococcus equi Subspecies zooepidemicus Bacteremia.
Madani A, Zeebregts CJ, Lamprou A, Tielliu IFJ. Madani A, et al. Aorta (Stamford). 2019 Dec;7(6):172-175. doi: 10.1055/s-0039-3401995. Epub 2020 Feb 19. Aorta (Stamford). 2019. PMID: 32074645 Free PMC article.
This report describes a case of a taxidermist who presented with sepsis and excruciating back pain a few weeks after contact with a deceased horse. Streptococcus equi subspecies zooepidemicus (SESZ) was isolated from patient's blood and two isolated mycotic a …
This report describes a case of a taxidermist who presented with sepsis and excruciating back pain a few weeks after contact with a d …
Indicators of Horse Welfare: State-of-the-Art.
Lesimple C. Lesimple C. Animals (Basel). 2020 Feb 13;10(2):294. doi: 10.3390/ani10020294. Animals (Basel). 2020. PMID: 32069888 Free PMC article. Review.
Animal welfare is defined as a chronic state reflecting an individual's subjective perception of its situation. Because it is possible to be in a good welfare state and nevertheless experience acute fear or pain, and conversely, short-term positive emotions can be e …
Animal welfare is defined as a chronic state reflecting an individual's subjective perception of its situation. Because it is possibl …
Effects of Low-Level Laser Therapy and Chiropractic Care on Back Pain in Quarter Horses.
Haussler KK, Manchon PT, Donnell JR, Frisbie DD. Haussler KK, et al. J Equine Vet Sci. 2020 Mar;86:102891. doi: 10.1016/j.jevs.2019.102891. Epub 2019 Dec 10. J Equine Vet Sci. 2020. PMID: 32067657
Low-level laser therapy has been used clinically to treat musculoskeletal pain; however, there is limited evidence available to support its use in treating back pain in horses. The objective of this study was to evaluate the clinical effectiveness of low-leve …
Low-level laser therapy has been used clinically to treat musculoskeletal pain; however, there is limited evidence available to suppo …
Modification of collagen-based sponges can induce an upshift of the early inflammatory response and a chronic inflammatory reaction led by M1 macrophages: an in vivo study.
Herrera-Vizcaíno C, Al-Maawi S, Sader R, Kirkpatrick CJ, Choukroun J, Ghanaati S. Herrera-Vizcaíno C, et al. Clin Oral Investig. 2020 Oct;24(10):3485-3500. doi: 10.1007/s00784-020-03219-2. Epub 2020 Feb 17. Clin Oral Investig. 2020. PMID: 32065310
CONCLUSION: Altering the original presentation of a hemostatic sponge biomaterial by pressing modified the initial biomaterial-cell interaction, delayed the early biomaterial's degradation rate, and altered the vascularization pattern. A pressed biomaterial seems to induce …
CONCLUSION: Altering the original presentation of a hemostatic sponge biomaterial by pressing modified the initial biomaterial-cell interact …
Sacral plexus catheter analgesia in a patient with traumatic sacral fractures and Tarlov cysts.
Ireland E, Womack J, Foley E. Ireland E, et al. Anaesth Rep. 2019 Sep 30;7(2):76-78. doi: 10.1002/anr3.12023. eCollection 2019 Jul-Dec. Anaesth Rep. 2019. PMID: 32051956 Free PMC article.
We report the use of a sacral plexus catheter for continuous local anaesthetic infusion in a patient with a unilateral sacral ala fracture following a fall from a horse. Although sacral plexus blockade has been well described for lower limb surgery, an ultrasound-guided co …
We report the use of a sacral plexus catheter for continuous local anaesthetic infusion in a patient with a unilateral sacral ala fracture f …
Enterolithiasis in horses: analysis of 15 cases treated surgically in Saudi Arabia.
Turek B, Witkowski M, Drewnowska O. Turek B, et al. Iran J Vet Res. 2019 Fall;20(4):270-276. Iran J Vet Res. 2019. PMID: 32042291 Free PMC article.
The earliest symptoms include weight loss and repeated episodes of colic pain. Aims: To present the results of operative treatment of 15 horses with enteroliths in Saudi Arabia. METHODS: Fifteen purebred Arabian horses in Saudi Arabia, aged between 2 and 18 y …
The earliest symptoms include weight loss and repeated episodes of colic pain. Aims: To present the results of operative treatment of …
Plasma disposition of gabapentin after the intragastric administration of escalating doses to adult horses.
Gold JR, Grubb TL, Green S, Cox S, Villarino NF. Gold JR, et al. J Vet Intern Med. 2020 Mar;34(2):933-940. doi: 10.1111/jvim.15724. Epub 2020 Feb 8. J Vet Intern Med. 2020. PMID: 32034928 Free PMC article.
No information exists on the pharmacokinetics of dosages >20 mg/kg, escalating dosages or dose proportionality of gabapentin in horses. HYPOTHESIS AND OBJECTIVES: Gabapentin exposure in plasma would not increase proportionally relative to the dose in horses recei …
No information exists on the pharmacokinetics of dosages >20 mg/kg, escalating dosages or dose proportionality of gabapentin in horses
A man in his 70s with neurological symptoms and progressive pain during cancer therapy.
Tholin B, Köster AK, Standal PA. Tholin B, et al. Tidsskr Nor Laegeforen. 2020 Jan 20;140(2). doi: 10.4045/tidsskr.19.0303. Print 2020 Feb 4. Tidsskr Nor Laegeforen. 2020. PMID: 32026856 Free article. English, Norwegian.
CASE PRESENTATION: A man in his seventies with Waldenstrom's macroglobulinaemia under treatment with ibrutinib contacted the outpatient clinic due to bilateral pain distal to the knees. ...Waldenstrom's macroglobulinaemia was present in the central nervous sy …
CASE PRESENTATION: A man in his seventies with Waldenstrom's macroglobulinaemia under treatment with ibrutinib contacted the outpatie …
In-Person Caretaker Visits Disrupt Ongoing Discomfort Behavior in Hospitalized Equine Orthopedic Surgical Patients.
Torcivia C, McDonnell S. Torcivia C, et al. Animals (Basel). 2020 Jan 27;10(2):210. doi: 10.3390/ani10020210. Animals (Basel). 2020. PMID: 32012670 Free PMC article.
Horses have evolved to show little indication of discomfort or disability when in the presence of potential predators, including humans. This natural characteristic complicates the recognition of pain in equine patients. It has been our clinical impression that, whe
Horses have evolved to show little indication of discomfort or disability when in the presence of potential predators, including huma
Intraoperative nociception-antinociception monitors: A review from the veterinary perspective.
Ruíz-López P, Domínguez JM, Granados MDM. Ruíz-López P, et al. Vet Anaesth Analg. 2020 Mar;47(2):152-159. doi: 10.1016/j.vaa.2019.09.006. Epub 2019 Nov 16. Vet Anaesth Analg. 2020. PMID: 32007442 Review.
A nociceptive-antinociceptive monitoring system based on the PNS response has been developed for use in cats, dogs and horses. It uses the parasympathetic tone activity index, which is believed to detect inadequate intraoperative nociception-antinociception balance in vete …
A nociceptive-antinociceptive monitoring system based on the PNS response has been developed for use in cats, dogs and horses. It use …
Generation of Domains for the Equine Musculoskeletal Rehabilitation Outcome Score: Development by Expert Consensus.
Tabor G, Nankervis K, Fernandes J, Williams J. Tabor G, et al. Animals (Basel). 2020 Jan 25;10(2):203. doi: 10.3390/ani10020203. Animals (Basel). 2020. PMID: 31991716 Free PMC article.
Outcome measures (OMs) are a requirement of professional practice standards in human and canine physiotherapy practice for measurement of health status. Measures such as pain and functional capacity of specific regions are used to track treatment impact and can be used to …
Outcome measures (OMs) are a requirement of professional practice standards in human and canine physiotherapy practice for measurement of he …
Effect of work on body language of ranch horses in Brazil.
Trindade PHE, Hartmann E, Keeling LJ, Andersen PH, Ferraz GC, Paranhos da Costa MJR. Trindade PHE, et al. PLoS One. 2020 Jan 28;15(1):e0228130. doi: 10.1371/journal.pone.0228130. eCollection 2020. PLoS One. 2020. PMID: 31990951 Free PMC article.
They also decreased the frequency/duration of body language indicative of attention and movements to avoid flies. However, some of these behaviours are also shown when horses are in pain, leading us to suggest that some ranch horses were probably experiencing …
They also decreased the frequency/duration of body language indicative of attention and movements to avoid flies. However, some of these beh …
Efficacy of orally administered gabapentin in horses with chronic thoracic limb lameness.
Young JM, Schoonover MJ, Kembel SL, Taylor JD, Bauck AG, Gilliam LL. Young JM, et al. Vet Anaesth Analg. 2020 Mar;47(2):259-266. doi: 10.1016/j.vaa.2019.11.003. Epub 2019 Dec 4. Vet Anaesth Analg. 2020. PMID: 31980368
CONCLUSIONS AND CLINICAL RELEVANCE: Gabapentin, as administered here, did not improve subjective or objective measures of lameness in horses with chronic thoracic limb musculoskeletal pain. Although subjective evaluation identified an improvement in lameness with tr …
CONCLUSIONS AND CLINICAL RELEVANCE: Gabapentin, as administered here, did not improve subjective or objective measures of lameness in hor
Morphine plasmatic concentration in a pregnant mare and its foal after long term epidural administration.
Mirra A, Birras J, Diez Bernal S, Spadavecchia C. Mirra A, et al. BMC Vet Res. 2020 Jan 20;16(1):19. doi: 10.1186/s12917-020-2242-9. BMC Vet Res. 2020. PMID: 31959188 Free PMC article.
BACKGROUND: Epidural administration of morphine has been shown to be an effective analgesic strategy in horses; however, the possible occurrence of side effects limits its usage. ...CONCLUSION: Prolonged epidural administration of morphine in a pregnant mare allowed good …
BACKGROUND: Epidural administration of morphine has been shown to be an effective analgesic strategy in horses; however, the possible …
Surgical osteochondral defect repair in the horse-a matter of form or function?
Fugazzola MC, van Weeren PR. Fugazzola MC, et al. Equine Vet J. 2020 Jul;52(4):489-499. doi: 10.1111/evj.13231. Epub 2020 Feb 19. Equine Vet J. 2020. PMID: 31958175 Free PMC article. Review.
Both types of lesion will therefore eventually lead to activity-related pain, swelling and decreased mobility and will frequently progress to osteoarthritis. ...Currently available surgical options for treatment of osteochondral lesions in the horse are summarised. …
Both types of lesion will therefore eventually lead to activity-related pain, swelling and decreased mobility and will frequently pro …
CTX-M-15 Producing Escherichia coli Sequence Type 361 and Sequence Type 38 Causing Bacteremia and Umbilical Infection in a Neonate Foal.
Shnaiderman-Torban A, Navon-Venezia S, Dahan R, Dor Z, Taulescu M, Paitan Y, Edery N, Steinman A. Shnaiderman-Torban A, et al. J Equine Vet Sci. 2020 Feb;85:102881. doi: 10.1016/j.jevs.2019.102881. Epub 2019 Dec 14. J Equine Vet Sci. 2020. PMID: 31952646
An eighteen-hour-old Tennessee walking horse foal was referred due to weakness and abdominal pain. Physical examination revealed dehydration, distended abdomen, and uveitis. ...
An eighteen-hour-old Tennessee walking horse foal was referred due to weakness and abdominal pain. Physical examination reveal