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Year Number of Results
2015 2
2016 2
2017 4
2018 1
2019 4
2020 7
2021 8
2022 16
2023 18
2024 17
2025 24
2026 9

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110 results

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Page 1
Cell-Free Supernatant of Bacillus subtilis Suppresses the Mycelial Growth of Penicillium expansum by Destroying the Cell Membrane Integrity and Provoking Cell Death.
Li H, Chen Y, Xie Z, Su Q, Chen B, Yang Y, Ma G, Yang Y, Shan X, Wang J, Yu S, Miao M. Li H, et al. Biology (Basel). 2026 Feb 13;15(4):326. doi: 10.3390/biology15040326. Biology (Basel). 2026. PMID: 41744635 Free PMC article.
The self-protective response elicited by 5% CFS is insufficient to counteract the extent of cellular damage, ultimately driving cells toward a dynamic, multistage, and disintegrative form of cell death. The findings of this study offer a theoretical foundation for managing …
The self-protective response elicited by 5% CFS is insufficient to counteract the extent of cellular damage, ultimately driving cells
Engineering chromatin loops to control cell fate: LoopID reveals catalytic-independent functions of epigenetic regulators.
Li H, Silva JCR. Li H, et al. Among authors: silva jcr. Cell Transplant. 2026 Jan-Dec;35:9636897261424577. doi: 10.1177/09636897261424577. Epub 2026 Feb 17. Cell Transplant. 2026. PMID: 41700022 Free PMC article.
Using LoopID, they profile the "looposome" in mouse embryonic stem cells (ESCs) and uncover an unexpected, catalytic-independent role for the histone demethylase JMJD2 (KDM4) in organizing chromatin architecture through phase-separated condensates. ...
Using LoopID, they profile the "looposome" in mouse embryonic stem cells (ESCs) and uncover an unexpected, catalytic-independe …
A CD47 antibody with minimized erythrocyte and thrombocyte toxicities.
Pei M, Dai XD, Jiang XF, Yuan CY, Tan J, He KF, Liu GJ, Zhu JD, Li HH, Pan AL, Wang YR, Chen YL, Chen XJ, Wang C. Pei M, et al. Front Oncol. 2025 Nov 26;15:1686180. doi: 10.3389/fonc.2025.1686180. eCollection 2025. Front Oncol. 2025. PMID: 41383500 Free PMC article.
It enhanced macrophage-mediated phagocytosis of tumor cells and showed potent antitumor effects as a monotherapy or in combination with a PD-1 antibody in tumor models. ...
It enhanced macrophage-mediated phagocytosis of tumor cells and showed potent antitumor effects as a monotherapy or in combination wi …
Signaling reprogramming via Stat3 activation unravels high-fidelity human post-implantation embryo modeling.
Chen C, Wu J, Wang X, Chang L, Wang K, Wu K, Guo M, Li H, Sun F, Jiang X, Ma Y, Pan G, Xiao Z, Silva JCR. Chen C, et al. Among authors: li h, silva jcr. Cell Stem Cell. 2025 Oct 2;32(10):1528-1544.e10. doi: 10.1016/j.stem.2025.08.011. Epub 2025 Sep 16. Cell Stem Cell. 2025. PMID: 40961945
Here, we investigate whether STAT3 activation can reprogram pluripotent stem cells (PSCs) into early fates that self-organize into embryo models. Using a medium enhancing STAT3 activity (SAM), PSCs reprogram within 60 h into hypoblast, trophectoderm, naive epiblast, …
Here, we investigate whether STAT3 activation can reprogram pluripotent stem cells (PSCs) into early fates that self-organize …
Mouse trophectoderm stem cells generated with morula signalling inducers capture an early trophectoderm state.
Gao Y, Li M, Guan W, Guo W, Wei S, Yan F, Han W, Zhang X, Yin T, Dang Y, Li H, Silva JCR, Zhang J. Gao Y, et al. Among authors: li h, silva jcr. Nat Cell Biol. 2025 Sep;27(9):1572-1586. doi: 10.1038/s41556-025-01732-8. Epub 2025 Aug 14. Nat Cell Biol. 2025. PMID: 40813453
Successful derivation of mouse trophoblast stem cells (TSCs) and trophectoderm stem cells (TESCs) has greatly facilitated the understanding of trophoblast differentiation. ...When partially differentiated MTSCs aggregate with embryonic stem c
Successful derivation of mouse trophoblast stem cells (TSCs) and trophectoderm stem cells (TESCs) has greatly fa …
A complete model of mouse embryogenesis through organogenesis enabled by chemically induced embryo founder cells.
Li H, Guan W, Huang J, Shen P, Wu J, Luo H, Yang Y, Ning S, Chang L, Zhao H, Chen C, Gao Y, Chen Y, Yang X, Costa Y, Cai CL, Pei D, Peng G, Wu G, Chen J, Zhang J, Jing N, Silva JCR. Li H, et al. Among authors: silva jcr. Cell. 2025 Oct 16;188(21):5912-5930.e20. doi: 10.1016/j.cell.2025.07.018. Epub 2025 Aug 7. Cell. 2025. PMID: 40780195 Free article.
Here, we employ a small-molecule-only approach to induce mouse embryonic stem cells into 8- to 16-cell-like embryo founder cells, enabling the generation of a complete embryo model. These founder cells specify all blastocyst lineages, both embryonic an …
Here, we employ a small-molecule-only approach to induce mouse embryonic stem cells into 8- to 16-cell-like embryo founder …
Epidemiology, molecular typing, microbiome-immune interactions and treatment strategies of endometrial cancer: a review.
Liang B, Tan J, Li J, Wang X, Li G, Li H, Li T, Gao H. Liang B, et al. Among authors: li h. Front Immunol. 2025 Jun 25;16:1595638. doi: 10.3389/fimmu.2025.1595638. eCollection 2025. Front Immunol. 2025. PMID: 40636107 Free PMC article. Review.
The complex interactions among the reproductive tract, host cells, and the microbial environment may harbor novel disease mechanisms. In this review, we provide an overview of the epidemiological characteristics, major risk factors, histological and molecular subtypes of e …
The complex interactions among the reproductive tract, host cells, and the microbial environment may harbor novel disease mechanisms. …
Inhibition of HDAC activity directly reprograms murine embryonic stem cells to trophoblast stem cells.
Huang B, Peng X, Zhai X, Hu J, Chen J, Yang S, Huang Q, Deng E, Li H, Barakat TS, Chen J, Pei D, Fan X, Chambers I, Zhang M. Huang B, et al. Among authors: li h. Dev Cell. 2024 Aug 19;59(16):2101-2117.e8. doi: 10.1016/j.devcel.2024.05.009. Epub 2024 May 31. Dev Cell. 2024. PMID: 38823394 Free article.
Embryonic stem cells (ESCs) can differentiate into all cell types of the embryonic germ layers. ...Here, we show that treating mouse ESCs with sodium butyrate (NaB) increases the population of 2C-like cells and enables direct reprogramming of ESCs into tropho …
Embryonic stem cells (ESCs) can differentiate into all cell types of the embryonic germ layers. ...Here, we show that treating …
Protocol for generating mouse morula-like cells resembling 8- to 16-cell stage embryo cells.
Li H, Chang L, Huang J, Silva JCR. Li H, et al. Among authors: silva jcr. STAR Protoc. 2024 Jun 21;5(2):102934. doi: 10.1016/j.xpro.2024.102934. Epub 2024 Mar 29. STAR Protoc. 2024. PMID: 38555588 Free PMC article.
Generating cell types with properties of embryo cells with full developmental potential is of great biological importance. Here, we present a protocol for generating mouse morula-like cells (MLCs) resembling 8- to 16-cell stage embryo cells. ...We then detail …
Generating cell types with properties of embryo cells with full developmental potential is of great biological importance. Here, we p …
110 results