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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 1
1968 3
1969 2
1970 5
1971 3
1972 2
1973 3
1974 2
1975 17
1976 8
1977 8
1978 10
1979 8
1980 6
1981 13
1982 18
1983 13
1984 20
1985 29
1986 23
1987 34
1988 32
1989 34
1990 35
1991 36
1992 42
1993 36
1994 72
1995 62
1996 78
1997 95
1998 124
1999 123
2000 138
2001 169
2002 141
2003 166
2004 190
2005 199
2006 249
2007 243
2008 277
2009 308
2010 285
2011 298
2012 302
2013 330
2014 325
2015 316
2016 331
2017 329
2018 327
2019 361
2020 334
2021 377
2022 214
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Search Results

6,507 results
Results by year
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Page 1
Exome sequencing and analysis of 454,787 UK Biobank participants.
Backman JD, Li AH, Marcketta A, Sun D, Mbatchou J, Kessler MD, Benner C, Liu D, Locke AE, Balasubramanian S, Yadav A, Banerjee N, Gillies CE, Damask A, Liu S, Bai X, Hawes A, Maxwell E, Gurski L, Watanabe K, Kosmicki JA, Rajagopal V, Mighty J; Regeneron Genetics Center; DiscovEHR, Jones M, Mitnaul L, Stahl E, Coppola G, Jorgenson E, Habegger L, Salerno WJ, Shuldiner AR, Lotta LA, Overton JD, Cantor MN, Reid JG, Yancopoulos G, Kang HM, Marchini J, Baras A, Abecasis GR, Ferreira MAR. Backman JD, et al. Nature. 2021 Nov;599(7886):628-634. doi: 10.1038/s41586-021-04103-z. Epub 2021 Oct 18. Nature. 2021. PMID: 34662886 Free PMC article.
When these were tested for association with 3,994 health-related traits, we found 564 genes with trait associations at P 2.18 10(-11). Rare variant associations were enriched in loci from genome-wide association studies (GWAS), but most (91%) we …
When these were tested for association with 3,994 health-related traits, we found 564 genes with trait associations at P 2.18 …
The atopic march and atopic multimorbidity: Many trajectories, many pathways.
Paller AS, Spergel JM, Mina-Osorio P, Irvine AD. Paller AS, et al. J Allergy Clin Immunol. 2019 Jan;143(1):46-55. doi: 10.1016/j.jaci.2018.11.006. Epub 2018 Nov 17. J Allergy Clin Immunol. 2019. PMID: 30458183 Review.
The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset. ...Recent investigations implicate disease severity and persistence, age of onset, parental atopic history, filaggrin (FLG) mutations, poly …
The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset. ...Rec …
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
Ferreira MAR, Mathur R, Vonk JM, Szwajda A, Brumpton B, Granell R, Brew BK, Ullemar V, Lu Y, Jiang Y; 23andMe Research Team; eQTLGen Consortium; BIOS Consortium, Magnusson PKE, Karlsson R, Hinds DA, Paternoster L, Koppelman GH, Almqvist C. Ferreira MAR, et al. Am J Hum Genet. 2019 Apr 4;104(4):665-684. doi: 10.1016/j.ajhg.2019.02.022. Epub 2019 Mar 28. Am J Hum Genet. 2019. PMID: 30929738 Free PMC article.
Collectively, 28 associations were not previously reported. For 96 COA-associated variants, including five variants that represent COA-specific risk factors, the risk allele was more common in COA- than in AOA-affected individuals. Conversely, we ident …
Collectively, 28 associations were not previously reported. For 96 COA-associated variants, including five variants
Asthma.
Martinez FD, Vercelli D. Martinez FD, et al. Lancet. 2013 Oct 19;382(9901):1360-72. doi: 10.1016/S0140-6736(13)61536-6. Epub 2013 Sep 13. Lancet. 2013. PMID: 24041942 Review.
Although the disease can start at any age, the first symptoms occur during childhood in most cases. Asthma has a strong genetic component, and genome-wide association studies have identified variations in several genes that slightly increase the risk of disea …
Although the disease can start at any age, the first symptoms occur during childhood in most cases. Asthma has a strong genetic compo …
Brittle asthma.
Graziani E, Petroianni A, Terzano C. Graziani E, et al. Eur Rev Med Pharmacol Sci. 2004 Jul-Aug;8(4):135-8. Eur Rev Med Pharmacol Sci. 2004. PMID: 15636398 Review.
Brittle asthma is a rare form of severe asthma characterized by a wide variation of Peak Expiratory Flow (PEF), in spite of heavy doses of steroides. ...Brittle asthma is a rare form of severe asthma, that the clinicians may recognize and treat …
Brittle asthma is a rare form of severe asthma characterized by a wide variation of Peak Expiratory Flow (PEF), in spit …
Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype.
Rago D, Pedersen CT, Huang M, Kelly RS, Gürdeniz G, Brustad N, Knihtilä H, Lee-Sarwar KA, Morin A, Rasmussen MA, Stokholm J, Bønnelykke K, Litonjua AA, Wheelock CE, Weiss ST, Lasky-Su J, Bisgaard H, Chawes BL. Rago D, et al. Am J Respir Crit Care Med. 2021 Apr 1;203(7):853-863. doi: 10.1164/rccm.202008-3206OC. Am J Respir Crit Care Med. 2021. PMID: 33535020 Free PMC article.
Rationale: A link among sphingolipids, 17q21 genetic variants, and childhood asthma has been suggested, but the underlying mechanisms and characteristics of such an asthma endotype remain to be elucidated.Objectives: To study the sphingolipid-associated
Rationale: A link among sphingolipids, 17q21 genetic variants, and childhood asthma has been suggested, but the underlying mec …
Epidemiology of Asthma and Influence of Ethnicity.
Moraes TJ, Sears MR, Subbarao P. Moraes TJ, et al. Semin Respir Crit Care Med. 2018 Feb;39(1):3-11. doi: 10.1055/s-0037-1618568. Epub 2018 Feb 10. Semin Respir Crit Care Med. 2018. PMID: 29427980 Review.
Asthma is a heterogeneous disorder with a complex etiology. Prevalence rates for asthma have been increasing in many countries over the past few decades. While it is unclear why this increase is occurring, the variation reported in asthma preval
Asthma is a heterogeneous disorder with a complex etiology. Prevalence rates for asthma have been increasing in many co
Asthma in Latin America.
Forno E, Gogna M, Cepeda A, Yañez A, Solé D, Cooper P, Avila L, Soto-Quiros M, Castro-Rodriguez JA, Celedón JC. Forno E, et al. Thorax. 2015 Sep;70(9):898-905. doi: 10.1136/thoraxjnl-2015-207199. Epub 2015 Jun 23. Thorax. 2015. PMID: 26103996 Free PMC article. Review.
Consistent with the diversity of Latin America, there is profound variability in asthma burden among and within countries in this region. Regional variation in asthma prevalence is likely multifactorial and due to genetics, perinatal exposures, diet, obesity, …
Consistent with the diversity of Latin America, there is profound variability in asthma burden among and within countries in this reg …
Occupational asthma.
Mapp CE, Boschetto P, Maestrelli P, Fabbri LM. Mapp CE, et al. Am J Respir Crit Care Med. 2005 Aug 1;172(3):280-305. doi: 10.1164/rccm.200311-1575SO. Epub 2005 Apr 28. Am J Respir Crit Care Med. 2005. PMID: 15860754 Review.
Substantial epidemiologic and clinical evidence indicates that agents inhaled at work can induce asthma. In industrialized countries, occupational factors have been implicated in 9 to 15% of all cases of adult asthma. Work-related asthma includes (1) immunolo …
Substantial epidemiologic and clinical evidence indicates that agents inhaled at work can induce asthma. In industrialized countries, …
Role of genomics in asthma exacerbations.
Herrera-Luis E, Hernandez-Pacheco N, Vijverberg SJ, Flores C, Pino-Yanes M. Herrera-Luis E, et al. Curr Opin Pulm Med. 2019 Jan;25(1):101-112. doi: 10.1097/MCP.0000000000000533. Curr Opin Pulm Med. 2019. PMID: 30334825 Review.
Although few genome-wide association studies of asthma exacerbations have been conducted up to date, they have revealed promising associations but with small effect sizes. Additionally, the analysis of interactions between genetic and environmental factors ha …
Although few genome-wide association studies of asthma exacerbations have been conducted up to date, they have revealed promis …
6,507 results