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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 1
1968 3
1969 2
1970 5
1971 3
1972 2
1973 3
1974 2
1975 17
1976 8
1977 8
1978 10
1979 8
1980 6
1981 13
1982 18
1983 13
1984 20
1985 29
1986 23
1987 34
1988 32
1989 34
1990 35
1991 36
1992 42
1993 36
1994 72
1995 62
1996 78
1997 95
1998 124
1999 123
2000 138
2001 169
2002 141
2003 166
2004 190
2005 199
2006 249
2007 243
2008 277
2009 308
2010 285
2011 298
2012 302
2013 330
2014 325
2015 316
2016 331
2017 329
2018 329
2019 361
2020 334
2021 384
2022 338
2023 264
2024 129

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6,958 results

Results by year

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Page 1
Exome sequencing and analysis of 454,787 UK Biobank participants.
Backman JD, Li AH, Marcketta A, Sun D, Mbatchou J, Kessler MD, Benner C, Liu D, Locke AE, Balasubramanian S, Yadav A, Banerjee N, Gillies CE, Damask A, Liu S, Bai X, Hawes A, Maxwell E, Gurski L, Watanabe K, Kosmicki JA, Rajagopal V, Mighty J; Regeneron Genetics Center; DiscovEHR; Jones M, Mitnaul L, Stahl E, Coppola G, Jorgenson E, Habegger L, Salerno WJ, Shuldiner AR, Lotta LA, Overton JD, Cantor MN, Reid JG, Yancopoulos G, Kang HM, Marchini J, Baras A, Abecasis GR, Ferreira MAR. Backman JD, et al. Nature. 2021 Nov;599(7886):628-634. doi: 10.1038/s41586-021-04103-z. Epub 2021 Oct 18. Nature. 2021. PMID: 34662886 Free PMC article.
When these were tested for association with 3,994 health-related traits, we found 564 genes with trait associations at P 2.18 10(-11). Rare variant associations were enriched in loci from genome-wide association studies (GWAS), but most (91%) we …
When these were tested for association with 3,994 health-related traits, we found 564 genes with trait associations at P 2.18 …
The atopic march and atopic multimorbidity: Many trajectories, many pathways.
Paller AS, Spergel JM, Mina-Osorio P, Irvine AD. Paller AS, et al. J Allergy Clin Immunol. 2019 Jan;143(1):46-55. doi: 10.1016/j.jaci.2018.11.006. Epub 2018 Nov 17. J Allergy Clin Immunol. 2019. PMID: 30458183 Review.
The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset. ...Recent investigations implicate disease severity and persistence, age of onset, parental atopic history, filaggrin (FLG) mutations, poly …
The atopic march recognizes the increased occurrence of asthma, allergic rhinitis, or both after atopic dermatitis (AD) onset. ...Rec …
Mendelian randomization study shows a causal effect of asthma on epilepsy risk.
Tang P, Guo X, Chong L, Li R. Tang P, et al. Front Immunol. 2023 Feb 13;14:1071580. doi: 10.3389/fimmu.2023.1071580. eCollection 2023. Front Immunol. 2023. PMID: 36860869 Free PMC article.
METHODS: Independent genetic variants strongly (P<5E-08) associated with asthma were from a recent meta-analysis of genome-wide association studies on 408,442 participants. ...CONCLUSION: The present MR study suggests that asthma is associ
METHODS: Independent genetic variants strongly (P<5E-08) associated with asthma were from a recent meta-analysis of …
Exploring the genetic association of allergic diseases with cardiovascular diseases: a bidirectional Mendelian randomization study.
Wang S, Liu H, Yang P, Wang Z, Hu P, Ye P, Xia J, Chen S. Wang S, et al. Front Immunol. 2023 Jun 2;14:1175890. doi: 10.3389/fimmu.2023.1175890. eCollection 2023. Front Immunol. 2023. PMID: 37334359 Free PMC article.
Genetic variants associated with AD, asthma, and CVD were identified and used as instrumental variables to investigate the genetically causal association between them. ...However, after a Bonferroni correction, only the association between as
Genetic variants associated with AD, asthma, and CVD were identified and used as instrumental variables to investigate …
Potential drug targets for asthma identified in the plasma and brain through Mendelian randomization analysis.
Wang Y, Wang J, Yan Z, Liu S, Xu W. Wang Y, et al. Front Immunol. 2023 Sep 21;14:1240517. doi: 10.3389/fimmu.2023.1240517. eCollection 2023. Front Immunol. 2023. PMID: 37809092 Free PMC article.
Specifically, in plasma, we found that an increase of one standard deviation in IL1R1 and ECM1 was associated with an increased risk of asthma, while an increase in ADAM19 was found to be protective. ...In the brain, per 10-fold increase in ECM1 (OR, 1.05; 95% CI, 1 …
Specifically, in plasma, we found that an increase of one standard deviation in IL1R1 and ECM1 was associated with an increased risk …
Asthma.
Martinez FD, Vercelli D. Martinez FD, et al. Lancet. 2013 Oct 19;382(9901):1360-72. doi: 10.1016/S0140-6736(13)61536-6. Epub 2013 Sep 13. Lancet. 2013. PMID: 24041942 Review.
Although the disease can start at any age, the first symptoms occur during childhood in most cases. Asthma has a strong genetic component, and genome-wide association studies have identified variations in several genes that slightly increase the risk of disea …
Although the disease can start at any age, the first symptoms occur during childhood in most cases. Asthma has a strong genetic compo …
Asthma in Latin America.
Forno E, Gogna M, Cepeda A, Yañez A, Solé D, Cooper P, Avila L, Soto-Quiros M, Castro-Rodriguez JA, Celedón JC. Forno E, et al. Thorax. 2015 Sep;70(9):898-905. doi: 10.1136/thoraxjnl-2015-207199. Epub 2015 Jun 23. Thorax. 2015. PMID: 26103996 Free PMC article. Review.
Consistent with the diversity of Latin America, there is profound variability in asthma burden among and within countries in this region. Regional variation in asthma prevalence is likely multifactorial and due to genetics, perinatal exposures, diet, obesity, …
Consistent with the diversity of Latin America, there is profound variability in asthma burden among and within countries in this reg …
Role of genomics in asthma exacerbations.
Herrera-Luis E, Hernandez-Pacheco N, Vijverberg SJ, Flores C, Pino-Yanes M. Herrera-Luis E, et al. Curr Opin Pulm Med. 2019 Jan;25(1):101-112. doi: 10.1097/MCP.0000000000000533. Curr Opin Pulm Med. 2019. PMID: 30334825 Review.
Although few genome-wide association studies of asthma exacerbations have been conducted up to date, they have revealed promising associations but with small effect sizes. Additionally, the analysis of interactions between genetic and environmental factors ha …
Although few genome-wide association studies of asthma exacerbations have been conducted up to date, they have revealed promis …
Occupational asthma.
Mapp CE, Boschetto P, Maestrelli P, Fabbri LM. Mapp CE, et al. Am J Respir Crit Care Med. 2005 Aug 1;172(3):280-305. doi: 10.1164/rccm.200311-1575SO. Epub 2005 Apr 28. Am J Respir Crit Care Med. 2005. PMID: 15860754 Review.
Substantial epidemiologic and clinical evidence indicates that agents inhaled at work can induce asthma. In industrialized countries, occupational factors have been implicated in 9 to 15% of all cases of adult asthma. Work-related asthma includes (1) immunolo …
Substantial epidemiologic and clinical evidence indicates that agents inhaled at work can induce asthma. In industrialized countries, …
Plasma adiponectin and risk of asthma: observational analysis, genetic Mendelian randomisation and meta-analysis.
Nielsen MB, Nordestgaard BG, Benn M, Çolak Y. Nielsen MB, et al. Thorax. 2022 Nov;77(11):1070-1077. doi: 10.1136/thoraxjnl-2021-217675. Epub 2021 Dec 23. Thorax. 2022. PMID: 34949725
OBJECTIVE: We tested the hypothesis that plasma adiponectin is associated observationally and causally (using genetic variants as instrumental variables) with risk of asthma. ...CONCLUSION: Observationally, high plasma adiponectin is associated with in …
OBJECTIVE: We tested the hypothesis that plasma adiponectin is associated observationally and causally (using genetic variants
6,958 results