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Year Number of Results
1878 1
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1920 1
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1954 1
1956 1
1959 2
1960 1
1961 2
1962 4
1963 4
1964 10
1965 7
1966 1
1967 2
1968 6
1969 6
1970 3
1971 7
1972 13
1973 12
1974 10
1975 10
1976 5
1977 6
1978 7
1979 14
1980 7
1981 10
1982 12
1983 15
1984 17
1985 15
1986 21
1987 21
1988 17
1989 32
1990 26
1991 26
1992 23
1993 27
1994 20
1995 29
1996 35
1997 30
1998 27
1999 39
2000 29
2001 37
2002 40
2003 22
2004 35
2005 39
2006 37
2007 34
2008 57
2009 56
2010 69
2011 64
2012 77
2013 69
2014 62
2015 72
2016 65
2017 66
2018 75
2019 108
2020 97
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2022 117
2023 70

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1,966 results

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Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
Nie C, Ding X, A R, Zheng M, Li Z, Pan S, Yang W. Nie C, et al. Life Sci. 2021 May 1;272:119248. doi: 10.1016/j.lfs.2021.119248. Epub 2021 Feb 20. Life Sci. 2021. PMID: 33621592
The principle purpose of this study is to validate the effect of hydrogen gas on IHD and further explore the mechanism of hydrogen gas in alleviating myocardial I/R injury and no-reflow phenomenon. ...KEY FINDINGS: The myocardial infarct size, no-reflow area, cardia …
The principle purpose of this study is to validate the effect of hydrogen gas on IHD and further explore the mechanism of hydrogen
A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease.
Tao G, Zhang G, Chen W, Yang C, Xue Y, Song G, Qin S. Tao G, et al. J Cell Mol Med. 2022 Jul;26(14):4113-4123. doi: 10.1111/jcmm.17456. Epub 2022 Jun 23. J Cell Mol Med. 2022. PMID: 35734974 Free PMC article. Clinical Trial.
We found that inhalation of hydrogen/oxygen improved serum lipid and liver enzymes. ...Hydrogen/oxygen inhalation improved systemic inflammation and liver histology. ...
We found that inhalation of hydrogen/oxygen improved serum lipid and liver enzymes. ...Hydrogen/oxygen inhalation
Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson's disease: a pilot study.
Yoritaka A, Kobayashi Y, Hayashi T, Saiki S, Hattori N. Yoritaka A, et al. Neurol Sci. 2021 Nov;42(11):4767-4770. doi: 10.1007/s10072-021-05489-4. Epub 2021 Jul 28. Neurol Sci. 2021. PMID: 34319514 Free PMC article. Clinical Trial.

RESULTS: Five participants were excluded due to deviation from the protocol of the total duration of inhalation < 112 h. No significant differences were seen in the change in the total Movement Disorder Society Unified Parkinson's Disease Rating Scale score from

RESULTS: Five participants were excluded due to deviation from the protocol of the total duration of inhalation < 112 h. No signif

Molecular Hydrogen as a Neuroprotective Agent.
Iketani M, Ohsawa I. Iketani M, et al. Curr Neuropharmacol. 2017;15(2):324-331. doi: 10.2174/1570159x14666160607205417. Curr Neuropharmacol. 2017. PMID: 27281176 Free PMC article. Review.
Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen (H2) functions as an antioxidant and anti-inflammatory agent. The routes of H2 administration in animal model and human clinical studies …
Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen (H2) …
Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
Kiyoi T, Liu S, Takemasa E, Nakaoka H, Hato N, Mogi M. Kiyoi T, et al. PLoS One. 2020 Apr 17;15(4):e0227582. doi: 10.1371/journal.pone.0227582. eCollection 2020. PLoS One. 2020. PMID: 32302306 Free PMC article.
Here, we investigated the effect of constitutive inhalation of hydrogen gas on vascular neointima formation using a cuff-induced vascular injury mouse model. After constitutive inhalation of compressed hydrogen gas (O2 21%, N2 77.7%, hydrogen 1. …
Here, we investigated the effect of constitutive inhalation of hydrogen gas on vascular neointima formation using a cuff-induc …
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Ohsawa I, et al. Nat Med. 2007 Jun;13(6):688-94. doi: 10.1038/nm1577. Epub 2007 May 7. Nat Med. 2007. PMID: 17486089
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H(2)) has potential as an antioxi …
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is …
Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats.
Liu B, Xue J, Zhang M, Wang M, Ma T, Zhao M, Gu Q, Qin S. Liu B, et al. Mol Med Rep. 2020 Oct;22(4):2860-2868. doi: 10.3892/mmr.2020.11364. Epub 2020 Jul 28. Mol Med Rep. 2020. PMID: 32945408 Free PMC article.
Rats were randomly divided into four groups: i) Control group, regular diet/air inhalation; ii) model group, HFFD/air inhalation; iii) low hydrogen group, HFFD/4% hydrogen inhalation; and iv) high hydrogen group, HFFD/67% hydrogen
Rats were randomly divided into four groups: i) Control group, regular diet/air inhalation; ii) model group, HFFD/air inhalation
Hydrogen peroxide poisoning.
Watt BE, Proudfoot AT, Vale JA. Watt BE, et al. Toxicol Rev. 2004;23(1):51-7. doi: 10.2165/00139709-200423010-00006. Toxicol Rev. 2004. PMID: 15298493 Review.
Concentrated hydrogen peroxide is caustic and exposure may result in local tissue damage. ...Oxygen gas embolism may produce multiple cerebral infarctions. Although most inhalational exposures cause little more than coughing and transient dyspnoea, inhalation
Concentrated hydrogen peroxide is caustic and exposure may result in local tissue damage. ...Oxygen gas embolism may produce multiple …
COVID-19 and molecular hydrogen inhalation.
Ostojic SM. Ostojic SM. Ther Adv Respir Dis. 2020 Jan-Dec;14:1753466620951051. doi: 10.1177/1753466620951051. Ther Adv Respir Dis. 2020. PMID: 32865158 Free PMC article. No abstract available.
Hydrogen inhalation enhances autophagy via the AMPK/mTOR pathway, thereby attenuating doxorubicin-induced cardiac injury.
Ma T, Yang L, Zhang B, Lv X, Gong F, Yang W. Ma T, et al. Int Immunopharmacol. 2023 Jun;119:110071. doi: 10.1016/j.intimp.2023.110071. Epub 2023 Apr 18. Int Immunopharmacol. 2023. PMID: 37080067
CONCLUSIONS: These results suggest that hydrogen inhalation can activate autophagy through the AMPK/mTOR pathway and protect against myocardial injury induced by doxorubicin. Hydrogen inhalation therapy may be a potential treatment for doxorubicin-indu …
CONCLUSIONS: These results suggest that hydrogen inhalation can activate autophagy through the AMPK/mTOR pathway and protect a …
1,966 results