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1948 2
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1950 9
1951 7
1952 10
1953 14
1954 19
1955 14
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1957 20
1958 11
1959 15
1960 10
1961 9
1962 38
1963 76
1964 199
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1966 189
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1970 827
1971 1114
1972 1235
1973 1334
1974 1489
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1976 339
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1978 343
1979 397
1980 379
1981 338
1982 425
1983 456
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1989 681
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1991 777
1992 798
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2000 994
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2002 1085
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2006 1587
2007 1726
2008 1898
2009 1963
2010 2101
2011 2529
2012 2604
2013 2636
2014 2714
2015 2840
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83,739 results

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Page 1
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Ohsawa I, et al. Nat Med. 2007 Jun;13(6):688-94. doi: 10.1038/nm1577. Epub 2007 May 7. Nat Med. 2007. PMID: 17486089
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H(2)) has potential as an antioxi …
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is …
Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders.
Wu C, Zou P, Feng S, Zhu L, Li F, Liu TC, Duan R, Yang L. Wu C, et al. Mol Neurobiol. 2023 Apr;60(4):1749-1765. doi: 10.1007/s12035-022-03175-w. Epub 2022 Dec 26. Mol Neurobiol. 2023. PMID: 36567361 Review.
Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals in ischemic stroke, molecular hydrogen's antioxidative and anti-inflammatory effects have aroused widespread interest. ...Thi …
Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals …
The Therapeutic Application of Hydrogen in Cancer: The Potential and Challenges.
Khiji MN, Arghidash F, Tanha GK, Zadeh RH, Ghorbani E, Khazaei M, Hassanian SM, Gataa IS, Lam AK, Giovannetti E, Ferns GA, Nazari E, Avan A. Khiji MN, et al. Curr Pharm Des. 2024;30(17):1295-1306. doi: 10.2174/0113816128296710240404040232. Curr Pharm Des. 2024. PMID: 38638053 Review.
Hydrogen therapy has emerged as a possible approach for both preventing and treating cancer. ...Furthermore, hydrogen therapy has been found to be safe and well-tolerated in clinical settings. Nonetheless, additional investigations are necessary to improve a compreh …
Hydrogen therapy has emerged as a possible approach for both preventing and treating cancer. ...Furthermore, hydrogen therapy …
Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.
Htun Y, Nakamura S, Kusaka T. Htun Y, et al. Pediatr Res. 2021 Mar;89(4):753-759. doi: 10.1038/s41390-020-0998-z. Epub 2020 Jun 6. Pediatr Res. 2021. PMID: 32505123 Review.
Current research interest in HIE is shifting toward new neuroprotective agents, as single agents or as adjuncts to therapeutic hypothermia. Here, we review therapeutic gases, particularly hydrogen, and their potentials and limitations in the treatment of HIE …
Current research interest in HIE is shifting toward new neuroprotective agents, as single agents or as adjuncts to therapeutic hypoth …
Molecular Hydrogen Therapy-A Review on Clinical Studies and Outcomes.
Johnsen HM, Hiorth M, Klaveness J. Johnsen HM, et al. Molecules. 2023 Nov 26;28(23):7785. doi: 10.3390/molecules28237785. Molecules. 2023. PMID: 38067515 Free PMC article. Review.
With its antioxidant properties, hydrogen gas (H(2)) has been evaluated in vitro, in animal studies and in human studies for a broad range of therapeutic indications. A simple search of "hydrogen gas" in various medical databases resulted in more than 2000 pu …
With its antioxidant properties, hydrogen gas (H(2)) has been evaluated in vitro, in animal studies and in human studies for a broad …
Advances in hydrogen delivery strategies for therapeutic applications.
Nguyen LD, Peng SY, Mac CH, Nguyen N, Lo SK, Lin PH, Pham NS, Chang HH, Lin YJ, Sung HW. Nguyen LD, et al. Adv Drug Deliv Rev. 2026 Jan;228:115734. doi: 10.1016/j.addr.2025.115734. Epub 2025 Nov 11. Adv Drug Deliv Rev. 2026. PMID: 41232804 Review.
Molecular hydrogen (H(2)) has emerged as a promising therapeutic agent owing to its selective antioxidant and anti-inflammatory properties, as well as its ability to modulate cellular signaling, metabolism, and immune responses. ...It then discusses current delivery …
Molecular hydrogen (H(2)) has emerged as a promising therapeutic agent owing to its selective antioxidant and anti-inflammator …
Recent advances in hydrogen research as a therapeutic medical gas.
Huang CS, Kawamura T, Toyoda Y, Nakao A. Huang CS, et al. Free Radic Res. 2010 Sep;44(9):971-82. doi: 10.3109/10715762.2010.500328. Free Radic Res. 2010. PMID: 20815764 Review.
Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen dissolved in water and injection with hydrogen-saturated saline. ...It is not an overstatement to say that hydrogen's …
Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen …
Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications.
Ye Y, Yu ZH, Nie L, Lu B, Mu G. Ye Y, et al. Mol Biol Rep. 2025 Jun 26;52(1):637. doi: 10.1007/s11033-025-10757-z. Mol Biol Rep. 2025. PMID: 40569354 Review.
Systematic analysis across diverse disease models-cardiac ischemia-reperfusion, neuroinflammation, metabolic dysfunction, and cancer-reveals hydrogen's remarkable context-dependent effects: cytoprotective in normal tissues while promoting therapeutic pyroptos …
Systematic analysis across diverse disease models-cardiac ischemia-reperfusion, neuroinflammation, metabolic dysfunction, and cancer-reveals …
Molecular hydrogen is a promising therapeutic agent for pulmonary disease.
Fu Z, Zhang J. Fu Z, et al. J Zhejiang Univ Sci B. 2022 Feb 15;23(2):102-122. doi: 10.1631/jzus.B2100420. J Zhejiang Univ Sci B. 2022. PMID: 35187885 Free PMC article. English.
Molecular hydrogen exerts biological effects on nearly all organs. It has anti-oxidative, anti-inflammatory, and anti-aging effects and contributes to the regulation of autophagy and cell death. ...In this review, we highlight the multiple functions of hydrogen and …
Molecular hydrogen exerts biological effects on nearly all organs. It has anti-oxidative, anti-inflammatory, and anti-aging effects a …
83,739 results
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