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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1963 1
1964 1
1970 1
1973 1
1977 1
1979 1
1982 2
1983 1
1984 1
1986 2
1988 2
1989 1
1993 1
1994 1
1995 3
1996 1
1997 1
1998 1
1999 5
2000 3
2001 2
2002 6
2003 3
2004 3
2005 6
2006 4
2007 5
2008 6
2009 10
2010 9
2011 18
2012 21
2013 22
2014 46
2015 42
2016 36
2017 50
2018 67
2019 65
2020 194
2021 184
2022 135
2023 31
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Search Results

871 results
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Page 1
Targeting autophagy in cancer.
Onorati AV, Dyczynski M, Ojha R, Amaravadi RK. Onorati AV, et al. Cancer. 2018 Aug;124(16):3307-3318. doi: 10.1002/cncr.31335. Epub 2018 Apr 19. Cancer. 2018. PMID: 29671878 Free PMC article. Review.
Early results from clinical trials that repurposed hydroxychloroquine for cancer have suggested that autophagy inhibition may be a promising approach for advanced cancers. ...Autophagy is a promising target for drug development in cancer. Cancer
Early results from clinical trials that repurposed hydroxychloroquine for cancer have suggested that autophagy inhibition may …
Targeting autophagy in cancer.
Levy JMM, Towers CG, Thorburn A. Levy JMM, et al. Nat Rev Cancer. 2017 Sep;17(9):528-542. doi: 10.1038/nrc.2017.53. Epub 2017 Jul 28. Nat Rev Cancer. 2017. PMID: 28751651 Free PMC article. Review.
Autophagy is a mechanism by which cellular material is delivered to lysosomes for degradation, leading to the basal turnover of cell components and providing energy and macromolecular precursors. Autophagy has opposing, context-dependent roles in cancer, and interventions …
Autophagy is a mechanism by which cellular material is delivered to lysosomes for degradation, leading to the basal turnover of cell compone …
Targeting Autophagy in Cancer: Recent Advances and Future Directions.
Amaravadi RK, Kimmelman AC, Debnath J. Amaravadi RK, et al. Cancer Discov. 2019 Sep;9(9):1167-1181. doi: 10.1158/2159-8290.CD-19-0292. Epub 2019 Aug 21. Cancer Discov. 2019. PMID: 31434711 Free PMC article. Review.
Certain cancer genotypes may be especially prone to autophagy inhibition. ...SIGNIFICANCE: Autophagy plays a complex role in cancer, but autophagy inhibition may be an effective therapeutic strategy in advanced cancer. ...
Certain cancer genotypes may be especially prone to autophagy inhibition. ...SIGNIFICANCE: Autophagy plays a complex role in cance
Targeting Autophagy in Breast Cancer.
Cocco S, Leone A, Piezzo M, Caputo R, Di Lauro V, Di Rella F, Fusco G, Capozzi M, Gioia GD, Budillon A, De Laurentiis M. Cocco S, et al. Int J Mol Sci. 2020 Oct 22;21(21):7836. doi: 10.3390/ijms21217836. Int J Mol Sci. 2020. PMID: 33105796 Free PMC article. Review.
Inhibition of autophagy could enhance tumor cell death by diverse anti-cancer therapies, representing an attractive approach to control mechanisms of drug resistance. In this manuscript, we present a review of autophagy focusing on its interplay with targeted drugs used fo …
Inhibition of autophagy could enhance tumor cell death by diverse anti-cancer therapies, representing an attractive approach to contr …
Hydroxychloroquine During Cancer Therapy.
Marmor MF. Marmor MF. Retin Cases Brief Rep. 2019 Spring;13(2):95-97. doi: 10.1097/ICB.0000000000000743. Retin Cases Brief Rep. 2019. PMID: 29781868 No abstract available.
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx.
Qi J, Xing Y, Liu Y, Wang MM, Wei X, Sui Z, Ding L, Zhang Y, Lu C, Fei YH, Liu N, Chen R, Wu M, Wang L, Zhong Z, Wang T, Liu Y, Wang Y, Liu J, Xu H, Guo F, Wang W. Qi J, et al. Autophagy. 2021 Dec;17(12):4401-4422. doi: 10.1080/15548627.2021.1917132. Epub 2021 Apr 23. Autophagy. 2021. PMID: 33890549 Free PMC article.
Macroautophagy/autophagy is elevated to ensure the high demand for nutrients for the growth of cancer cells. Here we demonstrated that MCOLN1/TRPML1 is a pharmaceutical target of oncogenic autophagy in cancers such as pancreatic cancer, breast cancer, …
Macroautophagy/autophagy is elevated to ensure the high demand for nutrients for the growth of cancer cells. Here we demonstrated tha …
COVID-19 in patients with lung cancer.
Luo J, Rizvi H, Preeshagul IR, Egger JV, Hoyos D, Bandlamudi C, McCarthy CG, Falcon CJ, Schoenfeld AJ, Arbour KC, Chaft JE, Daly RM, Drilon A, Eng J, Iqbal A, Lai WV, Li BT, Lito P, Namakydoust A, Ng K, Offin M, Paik PK, Riely GJ, Rudin CM, Yu HA, Zauderer MG, Donoghue MTA, Łuksza M, Greenbaum BD, Kris MG, Hellmann MD. Luo J, et al. Ann Oncol. 2020 Oct;31(10):1386-1396. doi: 10.1016/j.annonc.2020.06.007. Epub 2020 Jun 17. Ann Oncol. 2020. PMID: 32561401 Free PMC article.
Understanding the patient-specific and cancer-specific features that impact the severity of COVID-19 may inform optimal cancer care during this pandemic. ...Most patients recovered from COVID-19, including 25% patients initially requiring intubation. Among hospitali …
Understanding the patient-specific and cancer-specific features that impact the severity of COVID-19 may inform optimal cancer
The Role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases.
Martinez GP, Zabaleta ME, Di Giulio C, Charris JE, Mijares MR. Martinez GP, et al. Curr Pharm Des. 2020;26(35):4467-4485. doi: 10.2174/1381612826666200707132920. Curr Pharm Des. 2020. PMID: 32634079 Review.
Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of the heterocyclic aromatic compound quinoline. ...Currently, they are used as monotherapy or in conjunction with other therapies for the treatment of autoimmune diseases such as systemic lupus erythematosus (S …
Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of the heterocyclic aromatic compound quinoline. ...Currently, they are …
871 results