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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1963 1
1964 1
1970 1
1973 1
1977 1
1979 1
1982 2
1983 1
1984 1
1986 2
1988 2
1989 1
1993 1
1994 1
1995 3
1996 1
1997 1
1998 1
1999 5
2000 3
2001 2
2002 6
2003 3
2004 3
2005 6
2006 4
2007 5
2008 6
2009 10
2010 9
2011 18
2012 22
2013 22
2014 46
2015 42
2016 37
2017 50
2018 67
2019 65
2020 195
2021 186
2022 133
2023 81
2024 27

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941 results

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Page 1
Targeting autophagy in cancer.
Onorati AV, Dyczynski M, Ojha R, Amaravadi RK. Onorati AV, et al. Cancer. 2018 Aug;124(16):3307-3318. doi: 10.1002/cncr.31335. Epub 2018 Apr 19. Cancer. 2018. PMID: 29671878 Free PMC article. Review.
Early results from clinical trials that repurposed hydroxychloroquine for cancer have suggested that autophagy inhibition may be a promising approach for advanced cancers. ...Autophagy is a promising target for drug development in cancer. Cancer
Early results from clinical trials that repurposed hydroxychloroquine for cancer have suggested that autophagy inhibition may …
Targeting autophagy in cancer.
Levy JMM, Towers CG, Thorburn A. Levy JMM, et al. Nat Rev Cancer. 2017 Sep;17(9):528-542. doi: 10.1038/nrc.2017.53. Epub 2017 Jul 28. Nat Rev Cancer. 2017. PMID: 28751651 Free PMC article. Review.
Autophagy is a mechanism by which cellular material is delivered to lysosomes for degradation, leading to the basal turnover of cell components and providing energy and macromolecular precursors. Autophagy has opposing, context-dependent roles in cancer, and interventions …
Autophagy is a mechanism by which cellular material is delivered to lysosomes for degradation, leading to the basal turnover of cell compone …
Hydroxychloroquine During Cancer Therapy.
Marmor MF. Marmor MF. Retin Cases Brief Rep. 2019 Spring;13(2):95-97. doi: 10.1097/ICB.0000000000000743. Retin Cases Brief Rep. 2019. PMID: 29781868 No abstract available.
Targeting Autophagy in Cancer: Recent Advances and Future Directions.
Amaravadi RK, Kimmelman AC, Debnath J. Amaravadi RK, et al. Cancer Discov. 2019 Sep;9(9):1167-1181. doi: 10.1158/2159-8290.CD-19-0292. Epub 2019 Aug 21. Cancer Discov. 2019. PMID: 31434711 Free PMC article. Review.
Certain cancer genotypes may be especially prone to autophagy inhibition. ...SIGNIFICANCE: Autophagy plays a complex role in cancer, but autophagy inhibition may be an effective therapeutic strategy in advanced cancer. ...
Certain cancer genotypes may be especially prone to autophagy inhibition. ...SIGNIFICANCE: Autophagy plays a complex role in cance
Hydroxychloroquine: Key therapeutic advances and emerging nanotechnological landscape for cancer mitigation.
Low LE, Kong CK, Yap WH, Siva SP, Gan SH, Siew WS, Ming LC, Lai-Foenander AS, Chang SK, Lee WL, Wu Y, Khaw KY, Ong YS, Tey BT, Singh SK, Dua K, Chellappan DK, Goh BH. Low LE, et al. Chem Biol Interact. 2023 Dec 1;386:110750. doi: 10.1016/j.cbi.2023.110750. Epub 2023 Oct 13. Chem Biol Interact. 2023. PMID: 37839513 Free article. Review.
Hydroxychloroquine (HCQ) is a unique class of medications that has been widely utilized for the treatment of cancer. HCQ plays a dichotomous role by inhibiting autophagy induced by the tumor microenvironment (TME). Preclinical studies support the use of HCQ for anti
Hydroxychloroquine (HCQ) is a unique class of medications that has been widely utilized for the treatment of cancer. HCQ plays
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx.
Qi J, Xing Y, Liu Y, Wang MM, Wei X, Sui Z, Ding L, Zhang Y, Lu C, Fei YH, Liu N, Chen R, Wu M, Wang L, Zhong Z, Wang T, Liu Y, Wang Y, Liu J, Xu H, Guo F, Wang W. Qi J, et al. Autophagy. 2021 Dec;17(12):4401-4422. doi: 10.1080/15548627.2021.1917132. Epub 2021 Apr 23. Autophagy. 2021. PMID: 33890549 Free PMC article.
Macroautophagy/autophagy is elevated to ensure the high demand for nutrients for the growth of cancer cells. Here we demonstrated that MCOLN1/TRPML1 is a pharmaceutical target of oncogenic autophagy in cancers such as pancreatic cancer, breast cancer, …
Macroautophagy/autophagy is elevated to ensure the high demand for nutrients for the growth of cancer cells. Here we demonstrated tha …
Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms.
Ferreira PMP, Sousa RWR, Ferreira JRO, Militão GCG, Bezerra DP. Ferreira PMP, et al. Pharmacol Res. 2021 Jun;168:105582. doi: 10.1016/j.phrs.2021.105582. Epub 2021 Mar 26. Pharmacol Res. 2021. PMID: 33775862 Review.
Chloroquine (CQ) and hydroxychloroquine (HCQ) are the most common drugs used to relieve acute and chronic inflammatory diseases. ...Their sensitizing effects of chemotherapy when used as an adjuvant option in clinical trials against cancer. However, human related-MD …
Chloroquine (CQ) and hydroxychloroquine (HCQ) are the most common drugs used to relieve acute and chronic inflammatory diseases. ...T …
The Role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases.
Martinez GP, Zabaleta ME, Di Giulio C, Charris JE, Mijares MR. Martinez GP, et al. Curr Pharm Des. 2020;26(35):4467-4485. doi: 10.2174/1381612826666200707132920. Curr Pharm Des. 2020. PMID: 32634079 Review.
Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of the heterocyclic aromatic compound quinoline. ...Based on its effects on the modulation of the autophagy process, various clinical studies suggest that CQ and HCQ could be used in combination with other chemo …
Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of the heterocyclic aromatic compound quinoline. ...Based on its effect …
941 results