Twice-daily application of HIV microbicides alter the vaginal microbiota.
Ravel J, Gajer P, Fu L, Mauck CK, Koenig SS, Sakamoto J, Motsinger-Reif AA, Doncel GF, Zeichner SL.
Ravel J, et al.
mBio. 2012 Dec 18;3(6):e00370-12. doi: 10.1128/mBio.00370-12.
mBio. 2012.
PMID: 23249810
Free PMC article.
Clinical Trial.
We characterized vaginal microbiota, using pyrosequencing of bar-coded 16S rRNA gene fragments, in samples from 35 healthy, sexually abstinent female volunteer subjects (ages 18 to 50 years) with regular menses in a repeat phase 1 study of twice-daily application over 13.5 days o …
We characterized vaginal microbiota, using pyrosequencing of bar-coded 16S rRNA gene fragments, in samples from 35 healthy, sexually abstine …