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Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders.
Yew KS, Kamps-Schmitt KA, Borge R. Yew KS, et al. Am Fam Physician. 2021 Apr 15;103(8):481-492. Am Fam Physician. 2021. PMID: 33856167 Free article.
Hypermobile Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorders are the most common symptomatic joint hypermobility conditions seen in clinical practice. ...Hypermobile EDS and, less commonly, hypermobility spectrum disorders may also be …
Hypermobile Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorders are the most common symptomatic joint hyp …
Hypermobile Ehlers-Danlos Syndrome.
Hakim A. Hakim A. 2004 Oct 22 [updated 2024 Feb 22]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. 2004 Oct 22 [updated 2024 Feb 22]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. PMID: 20301456 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: Hypermobile Ehlers-Danlos syndrome (hEDS) is characterized by generalized joint hypermobility, joint instability, pain, soft and hyperextensible skin with atrophic scars and easy bruising, dental crowding, abdominal hernias, p …
CLINICAL CHARACTERISTICS: Hypermobile Ehlers-Danlos syndrome (hEDS) is characterized by generalized joint hypermobility …
Fascial Pathophysiology in Hypermobility Spectrum Disorders and Hypermobile Ehlers-Danlos Syndrome: A Review of Emerging Evidence.
Wang TJ, Stecco A, Hakim AJ, Schleip R. Wang TJ, et al. Int J Mol Sci. 2025 Jun 11;26(12):5587. doi: 10.3390/ijms26125587. Int J Mol Sci. 2025. PMID: 40565051 Free PMC article. Review.
Hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD) are increasingly recognized as complex, multisystem connective tissue disorders characterized by joint hypermobility and instability, chronic pain, autonomic dy …
Hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD) are increasingly recognized as com …
Complex Genetics and Regulatory Drivers of Hypermobile Ehlers-Danlos Syndrome: Insights from Genome-Wide Association Study Meta-analysis.
Petrucci-Nelson T, Guilhaumou S, Berrandou TE, Gensemer C, Georges A, Huff M, Fustier MA, Esmael A, Henry J, Jaye O, Phookan R, Dooley S, Byerly K, Loizzi B, Fenner R, Mach E, Weintraub A, Daylor V, Weninger J, Koren N, Bistran E, Griggs C, Griggs M, Severance S, Byrd R, Patel S, Kautz SA, Maitland A, Bouatia-Naji N, Norris RA. Petrucci-Nelson T, et al. medRxiv [Preprint]. 2025 Sep 21:2025.09.19.25336146. doi: 10.1101/2025.09.19.25336146. medRxiv. 2025. PMID: 41001447 Free PMC article. Preprint.
BACKGROUND: Hypermobile Ehlers-Danlos syndrome (hEDS) is the most common subtype of EDS, a group of heritable connective tissue disorders. Clinically, hEDS is defined by generalized joint hypermobility and chronic musculoskeletal pain, but its i …
BACKGROUND: Hypermobile Ehlers-Danlos syndrome (hEDS) is the most common subtype of EDS, a group of heritable connectiv …
AGA Clinical Practice Update on GI Manifestations and Autonomic or Immune Dysfunction in Hypermobile Ehlers-Danlos Syndrome: Expert Review.
Aziz Q, Harris LA, Goodman BP, Simrén M, Shin A. Aziz Q, et al. Clin Gastroenterol Hepatol. 2025 Jul;23(8):1291-1302. doi: 10.1016/j.cgh.2025.02.015. Epub 2025 May 19. Clin Gastroenterol Hepatol. 2025. PMID: 40387691 Review.
DESCRIPTION: The purpose of this Clinical Practice Update Expert Review is to describe key principles in the evaluation and management of patients with disorders of gut-brain interaction (DGBI) and hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobility sp …
DESCRIPTION: The purpose of this Clinical Practice Update Expert Review is to describe key principles in the evaluation and management of pa …
Ehlers-Danlos Syndrome.
Ravi U, Sieg VC. Ravi U, et al. 2023 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2023 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 31747221 Free Books & Documents.
Asymptomatic, nonsyndromic joint hypermobility, Ehlers-Danlos syndrome, and hypermobility spectrum disorders (particularly the hypermobile type) are the commonest phenotypes associated with joint hypermobility. Compilations of these syndromes can be chroni …
Asymptomatic, nonsyndromic joint hypermobility, Ehlers-Danlos syndrome, and hypermobility spectrum disorders (particularly the …
Exploring pain mechanisms in hypermobile Ehlers-Danlos syndrome: A case-control study.
De Wandele I, Colman M, Hermans L, Van Oosterwijck J, Meeus M, Rombaut L, Brusselmans G, Syx D, Calders P, Malfait F. De Wandele I, et al. Eur J Pain. 2022 Jul;26(6):1355-1367. doi: 10.1002/ejp.1956. Epub 2022 May 11. Eur J Pain. 2022. PMID: 35442549
BACKGROUND: The hypermobile type of Ehlers-Danlos syndrome (hEDS) is a heritable connective tissue disorder, associated with joint hypermobility and prominent chronic pain. ...OBJECTIVE: The present study assesses endogenous pain facilita …
BACKGROUND: The hypermobile type of Ehlers-Danlos syndrome (hEDS) is a heritable connective tissue disorder, associated …
Hypermobility spectrum disorders: A review.
Carroll MB. Carroll MB. Rheumatol Immunol Res. 2023 Jul 22;4(2):60-68. doi: 10.2478/rir-2023-0010. eCollection 2023 Jun. Rheumatol Immunol Res. 2023. PMID: 37637226 Free PMC article.
It remains a clinical challenge identifying when joint hypermobility (JH) is responsible for pain. Previous nomenclature utilized terms such as (benign) joint hypermobility syndrome (JHS) but this was updated in 2017 as advances in genetics provide a basis for nearly all v …
It remains a clinical challenge identifying when joint hypermobility (JH) is responsible for pain. Previous nomenclature utilized ter …
Chronic fatigue in Ehlers-Danlos syndrome-Hypermobile type.
Hakim A, De Wandele I, O'Callaghan C, Pocinki A, Rowe P. Hakim A, et al. Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):175-180. doi: 10.1002/ajmg.c.31542. Epub 2017 Feb 10. Am J Med Genet C Semin Med Genet. 2017. PMID: 28186393 Review.
Chronic fatigue is an important contributor to impaired health-related quality of life in Ehlers-Danlos syndrome. ...Other problems that commonly contribute to fatigue in EDS include sleep disorders, chronic pain, deconditioning, cardiovascular …
Chronic fatigue is an important contributor to impaired health-related quality of life in Ehlers-Danlos syndrome. ...Ot …
Hypermobility, the Ehlers-Danlos syndromes and chronic pain.
Syx D, De Wandele I, Rombaut L, Malfait F. Syx D, et al. Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 107(5):116-122. Epub 2017 Sep 28. Clin Exp Rheumatol. 2017. PMID: 28967365 Free article. Review.
In the absence of other conditions that cause chronic pain, these individuals are usually diagnosed with joint hypermobility syndrome (JHS). ...Clinical experience and a limited number of clinical studies show that chronic pain also is common in EDS pa …
In the absence of other conditions that cause chronic pain, these individuals are usually diagnosed with joint hypermobility s …
126 results