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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 2
1951 1
1956 1
1959 1
1960 3
1964 1
1966 3
1967 2
1970 3
1971 1
1972 1
1973 5
1974 4
1975 10
1976 11
1977 7
1978 6
1979 11
1980 8
1981 5
1982 11
1983 17
1984 19
1985 20
1986 13
1987 22
1988 15
1989 19
1990 20
1991 24
1992 39
1993 26
1994 42
1995 53
1996 49
1997 65
1998 50
1999 69
2000 61
2001 55
2002 66
2003 65
2004 58
2005 82
2006 92
2007 94
2008 126
2009 114
2010 143
2011 152
2012 162
2013 147
2014 175
2015 162
2016 191
2017 186
2018 200
2019 236
2020 278
2021 306
2022 261
2023 279
2024 274
2025 283
2026 179

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4,522 results

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Page 1
The Latest Strategy for Keloid and Hypertrophic Scar Prevention and Treatment: The Nippon Medical School (NMS) Protocol.
Ogawa R, Dohi T, Tosa M, Aoki M, Akaishi S. Ogawa R, et al. J Nippon Med Sch. 2021 Mar 11;88(1):2-9. doi: 10.1272/jnms.JNMS.2021_88-106. Epub 2020 Aug 1. J Nippon Med Sch. 2021. PMID: 32741903 Free article. Review.
In 2006, we established a scar/keloid-specialized unit in the Department of Plastic, Reconstructive, and Aesthetic Surgery at Nippon Medical School (NMS) in Tokyo, Japan. In the ensuing 15 years, we treated approximately 2,000 new scar/keloid patients annually. This …
In 2006, we established a scar/keloid-specialized unit in the Department of Plastic, Reconstructive, and Aesthetic Surgery at Nippon …
The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids: A 2020 Update of the Algorithms Published 10 Years Ago.
Ogawa R. Ogawa R. Plast Reconstr Surg. 2022 Jan 1;149(1):79e-94e. doi: 10.1097/PRS.0000000000008667. Plast Reconstr Surg. 2022. PMID: 34813576 Free PMC article. Review.
Treatment of hypertrophic scars depends on scar contracture severity: if severe, surgery is the first choice. ...Future high-quality trials are likely to improve the current hypertrophic scar and keloid treatment algorithms further....
Treatment of hypertrophic scars depends on scar contracture severity: if severe, surgery is the first choice. ...Future …
Intralesional Injection of Botulinum Toxin Type A Compared with Intralesional Injection of Corticosteroid for the Treatment of Hypertrophic Scar and Keloid: A Systematic Review and Meta-Analysis.
Bi M, Sun P, Li D, Dong Z, Chen Z. Bi M, et al. Med Sci Monit. 2019 Apr 22;25:2950-2958. doi: 10.12659/MSM.916305. Med Sci Monit. 2019. PMID: 31006769 Free PMC article.
BACKGROUND The optimal treatment for hypertrophic scar and keloid remains controversial. Therefore, the aim of this systematic review and meta-analysis was to compare the effectiveness of intralesional injection of botulinum toxin type A compared with placebo …
BACKGROUND The optimal treatment for hypertrophic scar and keloid remains controversial. Therefore, the aim of this sys …
Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment.
Berman B, Maderal A, Raphael B. Berman B, et al. Dermatol Surg. 2017 Jan;43 Suppl 1:S3-S18. doi: 10.1097/DSS.0000000000000819. Dermatol Surg. 2017. PMID: 27347634
OBJECTIVE: Objectives are to describe the pathophysiology of keloid and hypertrophic scar, and to compare differences with the normal wound healing process. The classification of keloids and hypertrophic scars are then discussed. ...Numerous treatments …
OBJECTIVE: Objectives are to describe the pathophysiology of keloid and hypertrophic scar, and to compare differences with the …
Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies.
Frech FS, Hernandez L, Urbonas R, Zaken GA, Dreyfuss I, Nouri K. Frech FS, et al. Am J Clin Dermatol. 2023 Mar;24(2):225-245. doi: 10.1007/s40257-022-00744-6. Epub 2023 Jan 20. Am J Clin Dermatol. 2023. PMID: 36662366 Review.
As there is no single, fully efficacious treatment modality, prevention remains the best approach in reducing aberrant scar formation. ...As such, management should be tailored to the individual patient's risk factors with the use of combination therapies to reduce …
As there is no single, fully efficacious treatment modality, prevention remains the best approach in reducing aberrant scar fo …
Hypertrophic Scar.
Bharadia SK, Burnett L, Gabriel V. Bharadia SK, et al. Phys Med Rehabil Clin N Am. 2023 Nov;34(4):783-798. doi: 10.1016/j.pmr.2023.05.002. Epub 2023 Jul 11. Phys Med Rehabil Clin N Am. 2023. PMID: 37806697 Review.
Hypertrophic scars frequently develop post-burn, and are characterized by their pruritic, painful, raised, erythematous, dyschromic, and contractile qualities. This article aims to synthesize knowledge on the clinical and molecular development, evolution, management, and m …
Hypertrophic scars frequently develop post-burn, and are characterized by their pruritic, painful, raised, erythematous, dyschromic, …
Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.
Gauglitz GG, Korting HC, Pavicic T, Ruzicka T, Jeschke MG. Gauglitz GG, et al. Mol Med. 2011 Jan-Feb;17(1-2):113-25. doi: 10.2119/molmed.2009.00153. Epub 2010 Oct 5. Mol Med. 2011. PMID: 20927486 Free PMC article. Review.
By causing pain, pruritus and contractures, excessive scarring significantly affects the patient's quality of life, both physically and psychologically. Multiple studies on hypertrophic scar and keloid formation have been conducted for decades and have led to a plet …
By causing pain, pruritus and contractures, excessive scarring significantly affects the patient's quality of life, both physically and psyc …
Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids.
Lee HJ, Jang YJ. Lee HJ, et al. Int J Mol Sci. 2018 Mar 2;19(3):711. doi: 10.3390/ijms19030711. Int J Mol Sci. 2018. PMID: 29498630 Free PMC article. Review.
There have been many studies on hypertrophic scars and keloids; but the mechanisms underlying scar formation have not yet been well established, and prophylactic and treatment strategies remain unsatisfactory. In this review, the authors introduce and summari …
There have been many studies on hypertrophic scars and keloids; but the mechanisms underlying scar formation have not yet been …
Update on hypertrophic scar treatment.
Rabello FB, Souza CD, Farina Júnior JA. Rabello FB, et al. Clinics (Sao Paulo). 2014 Aug;69(8):565-73. doi: 10.6061/clinics/2014(08)11. Clinics (Sao Paulo). 2014. PMID: 25141117 Free PMC article. Review.
The current review will focus on the definition of hypertrophic scars, distinguishing them from keloids and on the various methods for treating hypertrophic scarring that have been described in the literature, including treatments with clearly proven efficien …
The current review will focus on the definition of hypertrophic scars, distinguishing them from keloids and on the various methods fo …
Laser treatment of specific scar characteristics in hypertrophic scars and keloid: A systematic review.
Oosterhoff TCH, Beekman VK, van der List JP, Niessen FB. Oosterhoff TCH, et al. J Plast Reconstr Aesthet Surg. 2021 Jan;74(1):48-64. doi: 10.1016/j.bjps.2020.08.108. Epub 2020 Sep 20. J Plast Reconstr Aesthet Surg. 2021. PMID: 33645505
METHODS: A systematic literature review was performed using MEDLINE, Cochrane Library, and EMBASE. Data on scar characteristics were extracted from scar scales Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS), and from …
METHODS: A systematic literature review was performed using MEDLINE, Cochrane Library, and EMBASE. Data on scar characteristics were …
4,522 results