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Fibromyalgia: Chronic Pain Due to a Blood Dysfunction?
Aloisi AM, Casini I. Aloisi AM, et al. Int J Mol Sci. 2025 Apr 27;26(9):4153. doi: 10.3390/ijms26094153. Int J Mol Sci. 2025. PMID: 40362392 Free PMC article. Review.
Fibromyalgia (FM) is a common chronic disorder with chronic pain. FM generally affects all ages and occurs more commonly in women. ...Both aspects can interfere with tissue oxygenation and then with the numerous consequences induced by hypoxia. In this narrative rev
Fibromyalgia (FM) is a common chronic disorder with chronic pain. FM generally affects all ages and occurs more commonly in women. ..
Muscle pain syndromes and fibromyalgia: the role of muscle biopsy.
Ruggiero L, Manganelli F, Santoro L. Ruggiero L, et al. Curr Opin Support Palliat Care. 2018 Sep;12(3):382-387. doi: 10.1097/SPC.0000000000000355. Curr Opin Support Palliat Care. 2018. PMID: 29912728 Review.
Instead, the role of muscle biopsy in fibromyalgia is controversial. This review examines the reported studies with the objective to evaluate if some changes exist in the muscle, if these changes produce pain and if muscle biopsy is helpful in diagnostic flowchart of fi
Instead, the role of muscle biopsy in fibromyalgia is controversial. This review examines the reported studies with the objective to …
The muscle in fibromyalgia--a review of Swedish studies.
Bengtsson A, Henriksson KG. Bengtsson A, et al. J Rheumatol Suppl. 1989 Nov;19:144-9. J Rheumatol Suppl. 1989. PMID: 2691674 Review.
In Sweden, several studies have been performed in patients with fibromyalgia to study muscle morphology, chemistry and physiology in order to understand the origin of the most prominent symptoms in fibromyalgia: muscle pain, muscle fatigue and muscle stiffness. ...T …
In Sweden, several studies have been performed in patients with fibromyalgia to study muscle morphology, chemistry and physiology in …
Fibromyalgia syndrome: overnight falls in arterial oxygen saturation.
Alvarez Lario B, Alonso Valdivielso JL, Alegre López J, Martel Soteres C, Viejo Bañuelos JL, Marañón Cabello A. Alvarez Lario B, et al. Am J Med. 1996 Jul;101(1):54-60. doi: 10.1016/s0002-9343(96)00067-8. Am J Med. 1996. PMID: 8686716
PURPOSE: Sleep alterations and muscular changes suggesting hypoxia have been reported in fibromyalgia syndrome (FS) pathophysiology. We tested the hypothesis that patients with FS show falls in the oxygen saturation of hemoglobin in arterial blood (SaO2%) during sle …
PURPOSE: Sleep alterations and muscular changes suggesting hypoxia have been reported in fibromyalgia syndrome (FS) pathophysi …
A 77-Year-Old Woman With Capillary Hypoxia and Perioral Cyanosis.
Hodson DZ, Repetti GG, Hoesterey DT, Jeon Y, Bachour K, Mempin RL, Wang TS, Levine M. Hodson DZ, et al. Chest. 2022 Dec;162(6):e295-e299. doi: 10.1016/j.chest.2022.06.006. Chest. 2022. PMID: 36494128 Free PMC article.
She had been referred to the pulmonology clinic 3 years earlier to evaluate mild hypoxia with Spo(2) readings in the low 90% range, but pulmonary function testing failed to identify an etiology. ...Her rheumatologic conditions included osteoarthritis, rheumatoid arthritis, …
She had been referred to the pulmonology clinic 3 years earlier to evaluate mild hypoxia with Spo(2) readings in the low 90% range, b …
Clinical efficacy and mechanisms of hyperbaric oxygen therapy in the treatment of rheumatic and immune diseases.
Fang J, Li W, Liu C, Wang Y, Hu J, Sun Q, Wang H. Fang J, et al. Front Med (Lausanne). 2025 Dec 18;12:1706637. doi: 10.3389/fmed.2025.1706637. eCollection 2025. Front Med (Lausanne). 2025. PMID: 41488082 Free PMC article. Review.
Rheumatic and autoimmune diseases represent one of the major causes of chronic joint and muscle pain, skin ulceration, and mental depression, significantly impairing patients' physical and psychological wellbeing as well as their quality of life. Current evidence suggests that …
Rheumatic and autoimmune diseases represent one of the major causes of chronic joint and muscle pain, skin ulceration, and mental depression …
Cerebral vasomotor reactivity in fibromyalgia patients and its relationship to central neuropathic pain.
Sibel G , Kurtoglu HS , Kehaya S , Pamuk N , Celik Y . Sibel G , et al. Ideggyogy Sz. 2016 Sep 30;69(9-10):341-348. doi: 10.18071/isz.69.0341. Ideggyogy Sz. 2016. PMID: 29638096 Free article. English.
Background - Cerebral vasomotor reactivity, defined as the cerebral vasculature response to hypoxia, is not wellunderstood in fibromyalgia (FM) patients. This study investigated the difference in the cerebrovascular reactivity (i.e., responsiveness to hypercapnia wa …
Background - Cerebral vasomotor reactivity, defined as the cerebral vasculature response to hypoxia, is not wellunderstood in fibr
Muscle pain in neuromuscular disorders and primary fibromyalgia.
Henriksson KG. Henriksson KG. Neurologija. 1989;38(3):213-21. Neurologija. 1989. PMID: 2702325 Review.
In the chronic muscle pain syndrome called fibromyalgia (or fibrositis) the most likely cause of the pain is a combination of muscle tension and muscle hypoxia. ...The morphological and chemical findings are possibly a consequence of a long standing hypoxia. …
In the chronic muscle pain syndrome called fibromyalgia (or fibrositis) the most likely cause of the pain is a combination of muscle …
Total antioxidant capacity and the severity of the pain in patients with fibromyalgia.
Altindag O, Celik H. Altindag O, et al. Redox Rep. 2006;11(3):131-5. doi: 10.1179/135100006X116628. Redox Rep. 2006. PMID: 16805968 Free article.
The purpose of the study was to determine the oxidative and antioxidative status of plasma in patients with fibromyalgia. Total antioxidant capacity (TAC) of plasma was significantly lower in patients with fibromyalgia (n = 20) than in healthy controls (n = 20) [1.5 …
The purpose of the study was to determine the oxidative and antioxidative status of plasma in patients with fibromyalgia. Total antio …
Abnormal microcirculation and temperature in skin above tender points in patients with fibromyalgia.
Jeschonneck M, Grohmann G, Hein G, Sprott H. Jeschonneck M, et al. Rheumatology (Oxford). 2000 Aug;39(8):917-21. doi: 10.1093/rheumatology/39.8.917. Rheumatology (Oxford). 2000. PMID: 10952750 Free article.
OBJECTIVE: Skin temperature and skin blood flow were studied above different tender points in 20 patients with fibromyalgia (FM) and 20 healthy controls. METHODS: Blood flow was measured by laser Doppler flowmetry and skin temperature was measured with an infrared thermome …
OBJECTIVE: Skin temperature and skin blood flow were studied above different tender points in 20 patients with fibromyalgia (FM) and …
24 results