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The following terms were not found in PubMed: iNOS+Cinnamomi, cortex+COX-II+free
Page 1
Antioxidants and antioxidant methods: an updated overview.
Gulcin İ. Gulcin İ. Arch Toxicol. 2020 Mar;94(3):651-715. doi: 10.1007/s00204-020-02689-3. Epub 2020 Mar 16. Arch Toxicol. 2020. PMID: 32180036 Review.
.-)), hydrogen peroxide (H(2)O(2)) scavenging assay, hydroxyl radical (OH.) scavenging assay, singlet oxygen ((1)O(2)) quenching assay, nitric oxide radical (NO.) scavenging assay and chemiluminescence assay are outlined and critically discussed. ...
.-)), hydrogen peroxide (H(2)O(2)) scavenging assay, hydroxyl radical (OH.) scavenging assay, singlet oxygen ((1)O(2)) quenching assay, nitr …
Benefits of L-Arginine on Cardiovascular System.
Sudar-Milovanovic E, Obradovic M, Jovanovic A, Zaric B, Zafirovic S, Panic A, Radak D, Isenovic ER. Sudar-Milovanovic E, et al. Mini Rev Med Chem. 2016;16(2):94-103. doi: 10.2174/1389557515666151016125826. Mini Rev Med Chem. 2016. PMID: 26471966 Review.
Data from the literature show that L-Arg is the only substrate for the production of nitric oxide (NO), from which L-Arg develops its effects on the cardiovascular system. As a free radical, NO is synthesized in all mammalian cells by L-Arg with the activity of NO s …
Data from the literature show that L-Arg is the only substrate for the production of nitric oxide (NO), from which L-Arg develops its effect …
Prostacyclin among prostanoids.
Gryglewski RJ. Gryglewski RJ. Pharmacol Rep. 2008 Jan-Feb;60(1):3-11. Pharmacol Rep. 2008. PMID: 18276980 Free article. Review.
In that respect PGI(2) collaborates with the system consisting of NO synthase (eNOS)/nitric oxide free radical (NO)/guanylate cyclase/cyclic-GMP. Both cyclic nucleotides (c-AMP and c-GMP) act in synergy as two energetic fists which defend the cellular machinery from …
In that respect PGI(2) collaborates with the system consisting of NO synthase (eNOS)/nitric oxide free radical (NO)/guanylate …
NO: the primary EDRF.
Fleming I, Busse R. Fleming I, et al. J Mol Cell Cardiol. 1999 Jan;31(1):5-14. doi: 10.1006/jmcc.1998.0839. J Mol Cell Cardiol. 1999. PMID: 10072711 Review.
None of these autacoids play such a central role in the regulation of vascular tone and homeostasis as the primary EDRF, the free radical NO, which is generated via a live-electron oxidation of a guanidino nitrogen from L-arginine by an NO synthase (NOS)....
None of these autacoids play such a central role in the regulation of vascular tone and homeostasis as the primary EDRF, the free radical
Heavy metals: toxicity and human health effects.
Jomova K, Alomar SY, Nepovimova E, Kuca K, Valko M. Jomova K, et al. Arch Toxicol. 2025 Jan;99(1):153-209. doi: 10.1007/s00204-024-03903-2. Epub 2024 Nov 20. Arch Toxicol. 2025. PMID: 39567405 Free PMC article. Review.
Conversely, some heavy metals, such as cadmium, can suppress the synthesis of nitric oxide radical (NO(.)), manifested by altered vasorelaxation and, consequently, blood pressure regulation. ...
Conversely, some heavy metals, such as cadmium, can suppress the synthesis of nitric oxide radical (NO(.)), manifested by alte …
Small molecules for great solutions: Can nitric oxide-releasing nanomaterials overcome drug resistance in chemotherapy?
Pieretti JC, Pelegrino MT, Nascimento MHM, Tortella GR, Rubilar O, Seabra AB. Pieretti JC, et al. Biochem Pharmacol. 2020 Jun;176:113740. doi: 10.1016/j.bcp.2019.113740. Epub 2019 Nov 28. Biochem Pharmacol. 2020. PMID: 31786262 Free article. Review.
NO can have a direct toxic effect on tumors, or it can sensitize cancer cells and contribute to the reversal of multidrug resistance (MDR). As NO is a gas and free radical, NO donors have been investigated for their anticancer effects. In recent years, the combinati …
NO can have a direct toxic effect on tumors, or it can sensitize cancer cells and contribute to the reversal of multidrug resistance (MDR). …
The Role of Reactive Species on Innate Immunity.
Andrés CMC, Pérez de la Lastra JM, Juan CA, Plou FJ, Pérez-Lebeña E. Andrés CMC, et al. Vaccines (Basel). 2022 Oct 17;10(10):1735. doi: 10.3390/vaccines10101735. Vaccines (Basel). 2022. PMID: 36298601 Free PMC article. Review.
Reactive nitrogen species RNS (the most important are nitric oxide radical -()NO, peroxynitrite ONOO(-) and its derivatives), are also harmful to microorganisms, including bacteria, viruses, and parasites. ...
Reactive nitrogen species RNS (the most important are nitric oxide radical -()NO, peroxynitrite ONOO(-) and its derivatives), …
Hydrophilic carbon clusters as therapeutic, high-capacity antioxidants.
Samuel EL, Duong MT, Bitner BR, Marcano DC, Tour JM, Kent TA. Samuel EL, et al. Trends Biotechnol. 2014 Oct;32(10):501-5. doi: 10.1016/j.tibtech.2014.08.005. Epub 2014 Aug 28. Trends Biotechnol. 2014. PMID: 25175886 Free PMC article. Review.
PEG-HCCs show high capacity to annihilate ROS such as superoxide (O2(-)) and the hydroxyl (HO()) radical, show no reactivity toward the nitric oxide radical (NO()), and can be functionalized with targeting moieties without loss of activity. ...
PEG-HCCs show high capacity to annihilate ROS such as superoxide (O2(-)) and the hydroxyl (HO()) radical, show no reactivity toward the nitr …
Mechanism of action of hydroxyurea.
Yarbro JW. Yarbro JW. Semin Oncol. 1992 Jun;19(3 Suppl 9):1-10. Semin Oncol. 1992. PMID: 1641648 Review.
Hydroxyurea renders cells sensitive to bleomycin because the quenched tyrosyl free radical no longer stabilizes the adjacent iron center, making it more susceptible to the chelating properties of bleomycin, which then produces active oxygen. ...
Hydroxyurea renders cells sensitive to bleomycin because the quenched tyrosyl free radical no longer stabilizes the adjacent i …
Don't just say no: Differential pathways and pharmacological responses to diverse nitric oxide donors.
Chiesa JJ, Baidanoff FM, Golombek DA. Chiesa JJ, et al. Biochem Pharmacol. 2018 Oct;156:1-9. doi: 10.1016/j.bcp.2018.08.002. Epub 2018 Aug 3. Biochem Pharmacol. 2018. PMID: 30080991 Review.
Nitric oxide (NO) is a gaseous free radical molecule with a short half-life (1 s), which can gain or lose an electron into three interchangeable redox-dependent forms, the radical (NO), the nitrosonium cation (NO(+)), and nitroxyl anion (HNO). NO acts as an intra an …
Nitric oxide (NO) is a gaseous free radical molecule with a short half-life (1 s), which can gain or lose an electron into three interchange …
292 results