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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 1
1973 4
1974 1
1975 3
1976 3
1977 5
1978 11
1979 10
1980 8
1981 8
1982 5
1983 9
1984 14
1985 14
1986 11
1987 12
1988 15
1989 16
1990 31
1991 33
1992 36
1993 29
1994 33
1995 34
1996 31
1997 38
1998 38
1999 33
2000 60
2001 39
2002 46
2003 46
2004 60
2005 54
2006 63
2007 62
2008 75
2009 66
2010 65
2011 70
2012 68
2013 79
2014 52
2015 67
2016 84
2017 109
2018 96
2019 88
2020 98
2021 104
2022 79
2023 63
2024 84
2025 66
2026 6

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2,111 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.
Ohlsson A, Walia R, Shah SS. Ohlsson A, et al. Cochrane Database Syst Rev. 2020 Feb 11;2(2):CD003481. doi: 10.1002/14651858.CD003481.pub8. Cochrane Database Syst Rev. 2020. PMID: 32045960 Free PMC article.
Early versus expectant administration of IV ibuprofen, echocardiographically-guided IV ibuprofen treatment versus standard IV ibuprofen treatment, continuous infusion of ibuprofen versus intermittent boluses of ibuprofen, and rectal ibuprofen …
Early versus expectant administration of IV ibuprofen, echocardiographically-guided IV ibuprofen treatment versus standard IV …
Ibuprofen versus paracetamol for treating fever in preschool children in Nigeria: a randomized clinical trial of effectiveness and safety.
Alaje EO, Udoh EE, Akande PA, Odey FA, Meremikwu MM. Alaje EO, et al. Pan Afr Med J. 2020 Aug 26;36:350. doi: 10.11604/pamj.2020.36.350.21393. eCollection 2020. Pan Afr Med J. 2020. PMID: 33224416 Free PMC article. Clinical Trial.
The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and paracetamol in treating fever in under-fives were conducted in Europe and North America with very few in African children. ...RESULTS: the …
The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen an …
Post-Tonsillectomy Ibuprofen: Is There a Dose-Dependent Bleeding Risk?
Losorelli SD, Scheffler P, Qian ZJ, Lin HC, Truong MT. Losorelli SD, et al. Laryngoscope. 2022 Jul;132(7):1473-1481. doi: 10.1002/lary.29876. Epub 2021 Sep 24. Laryngoscope. 2022. PMID: 34559405
OBJECTIVES/HYPOTHESIS: Post-tonsillectomy hemorrhage (PTH) is a potentially life-threatening complication. A recent meta-analysis suggests that ibuprofen may increase the risk of PTH. The aims of this study were to 1) re-evaluate the effect of ibuprofen on PTH given …
OBJECTIVES/HYPOTHESIS: Post-tonsillectomy hemorrhage (PTH) is a potentially life-threatening complication. A recent meta-analysis suggests t …
The association between ibuprofen administration in children and the risk of developing or exacerbating asthma: a systematic review and meta-analysis.
Baxter L, Cobo MM, Bhatt A, Slater R, Sanni O, Shinde N. Baxter L, et al. BMC Pulm Med. 2024 Aug 26;24(1):412. doi: 10.1186/s12890-024-03179-3. BMC Pulm Med. 2024. PMID: 39187775 Free PMC article.
BACKGROUND: Ibuprofen is one of the most commonly used analgesic and antipyretic drugs in children. ...RESULTS: Comparing ibuprofen with active comparators, there was no evidence of a higher risk associated with ibuprofen over both the short and long term in …
BACKGROUND: Ibuprofen is one of the most commonly used analgesic and antipyretic drugs in children. ...RESULTS: Comparing ibuprofe …
Pharmacokinetics and Bioavailability of a Fixed-Dose Combination of Ibuprofen and Paracetamol after Intravenous and Oral Administration.
Atkinson HC, Stanescu I, Frampton C, Salem II, Beasley CP, Robson R. Atkinson HC, et al. Clin Drug Investig. 2015 Oct;35(10):625-32. doi: 10.1007/s40261-015-0320-8. Clin Drug Investig. 2015. PMID: 26334726 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: Previously published studies have suggested the lack of a pharmacokinetic interaction between ibuprofen and paracetamol when they are delivered as a fixed-dose oral combination. The aim of this study was to determine the pharmacokinetic profile a …
BACKGROUND AND OBJECTIVES: Previously published studies have suggested the lack of a pharmacokinetic interaction between ibuprofen an …
Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study.
Lyngstad G, Skjelbred P, Swanson DM, Skoglund LA. Lyngstad G, et al. Eur J Clin Pharmacol. 2021 Dec;77(12):1843-1852. doi: 10.1007/s00228-021-03231-9. Epub 2021 Oct 16. Eur J Clin Pharmacol. 2021. PMID: 34655316 Free PMC article. Clinical Trial.
Paracetamol 1000/codeine 60 mg gives similar analgesia as ibuprofen from 400 mg, but has a shorter time to analgesic onset. Active drugs show no significant difference in maximal analgesic effect. ...NNT and NTTp values did not coincide well with PROMs. CONCLUSION: Ibup …
Paracetamol 1000/codeine 60 mg gives similar analgesia as ibuprofen from 400 mg, but has a shorter time to analgesic onset. Active dr …
Single-Blind Randomized Controlled Trial: Comparative Efficacy of Dark Chocolate, Coconut Water, and Ibuprofen in Managing Primary Dysmenorrhea.
Nuha K, Rusmil K, Ganiem AR, Permadi W, Diah Herawati DM. Nuha K, et al. Int J Environ Res Public Health. 2023 Aug 21;20(16):6619. doi: 10.3390/ijerph20166619. Int J Environ Res Public Health. 2023. PMID: 37623203 Free PMC article. Clinical Trial.
Various pharmacological and non-pharmacological treatments are available for pain relief, but information on their effectiveness, particularly regarding green coconut water, dark chocolate, and Ibuprofen, remains limited. This study aimed to compare the effectiveness of gr …
Various pharmacological and non-pharmacological treatments are available for pain relief, but information on their effectiveness, particular …
Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.
Ohlsson A, Walia R, Shah SS. Ohlsson A, et al. Cochrane Database Syst Rev. 2018 Sep 28;9(9):CD003481. doi: 10.1002/14651858.CD003481.pub7. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2020 Feb 11;2:CD003481. doi: 10.1002/14651858.CD003481.pub8. PMID: 30264852 Free PMC article. Updated.
There was a decreased risk of failure to close a PDA with high-dose versus standard-dose of IV ibuprofen (3 studies 190 infants; typical RR 0.37, 95% CI 0.22 to 0.61; typical RD - 0.26, 95% CI -0.38 to -0.15; NNTB 4, 95% CI 3 to 7); I(2) = 4% for RR and 0% for RD); moderat …
There was a decreased risk of failure to close a PDA with high-dose versus standard-dose of IV ibuprofen (3 studies 190 infants; typi …
Postoperative Bleeding Associated with Ibuprofen Use after Tonsillectomy: A Meta-analysis.
Stokes W, Swanson RT, Schubart J, Carr MM. Stokes W, et al. Otolaryngol Head Neck Surg. 2019 Nov;161(5):734-741. doi: 10.1177/0194599819852328. Epub 2019 Jun 4. Otolaryngol Head Neck Surg. 2019. PMID: 31159669
OBJECTIVE: To better quantify the risk of ibuprofen-associated posttonsillectomy hemorrhage (PTH). DATA SOURCES: PUBMED/MEDLINE, Web of Science, and Cochrane Clinical Trials Database. REVIEW METHOD: Literature searches were performed for English-language publications conta …
OBJECTIVE: To better quantify the risk of ibuprofen-associated posttonsillectomy hemorrhage (PTH). DATA SOURCES: PUBMED/MEDLINE, Web …
2,111 results