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2019 1
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2023 62
2024 50

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232 results

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Corrigendum to "Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway" [Biomed. Pharmacother. 175 (2024) 116785].
Alburquerque-González B, Montoro-García S, Bernabé-García Á, Bernabé-García M, Campioni-Rodrigues P, Rodríguez-Martínez A, Luque I, Salo T, Pérez-Garrido A, Pérez-Sánchez H, Cayuela ML, Luengo-Gil G, Luchinat E, Postigo-Corrales F, Staderini T, Nicolás FJ, Conesa-Zamora P. Alburquerque-González B, et al. Biomed Pharmacother. 2024 Sep 9:117411. doi: 10.1016/j.biopha.2024.117411. Online ahead of print. Biomed Pharmacother. 2024. PMID: 39256102 No abstract available.
Lynch syndrome-associated and sporadic microsatellite unstable colorectal cancers: different patterns of clonal evolution yield highly similar tumours.
Martin S, Katainen R, Taira A, Välimäki N, Ristimäki A, Seppälä T, Renkonen-Sinisalo L, Lepistö A, Tahkola K, Mattila A, Koskensalo S, Mecklin JP, Rajamäki K, Palin K, Aaltonen LA. Martin S, et al. Hum Mol Genet. 2024 Aug 24:ddae124. doi: 10.1093/hmg/ddae124. Online ahead of print. Hum Mol Genet. 2024. PMID: 39180486
Microsatellite unstable colorectal cancer (MSI-CRC) can arise through germline mutations in mismatch repair (MMR) genes in individuals with Lynch syndrome (LS), or sporadically through promoter methylation of the MMR gene MLH1. ...
Microsatellite unstable colorectal cancer (MSI-CRC) can arise through germline mutations in mismatch repair (MMR) genes in individual …
Attention-based approach to predict drug-target interactions across seven target superfamilies.
Schulman A, Rousu J, Aittokallio T, Tanoli Z. Schulman A, et al. Bioinformatics. 2024 Aug 2;40(8):btae496. doi: 10.1093/bioinformatics/btae496. Bioinformatics. 2024. PMID: 39115379
Therefore, a comprehensive understanding of primary, secondary and even inactive targets becomes essential in the quest for effective and safe treatments for cancer and other indications. The human proteome offers over a thousand druggable targets, yet most FDA-approved dr …
Therefore, a comprehensive understanding of primary, secondary and even inactive targets becomes essential in the quest for effective and sa …
Clinical and molecular risk factors for repeat interventions due to symptomatic uterine leiomyomas.
Khamaiseh S, Äyräväinen A, Arffman M, Reinikka S, Mehine M, Härkki P, Bützow R, Pasanen A, Vahteristo P. Khamaiseh S, et al. Am J Obstet Gynecol. 2024 Jul 31:S0002-9378(24)00809-3. doi: 10.1016/j.ajog.2024.06.051. Online ahead of print. Am J Obstet Gynecol. 2024. PMID: 39094728 Free article.
All these patients harbored a germline fumarate hydratase mutation, which is distinctive for the hereditary leiomyomatosis and renal cell cancer syndrome. Finally, we identified 3 (3/33; 9%) patients with 2 tumors each displaying somatic mutations in a recently identified …
All these patients harbored a germline fumarate hydratase mutation, which is distinctive for the hereditary leiomyomatosis and renal cell …
Transposable elements as drivers of dedifferentiation: Connections between enhancers in embryonic stem cells, placenta, and cancer.
Karttunen K, Patel D, Sahu B. Karttunen K, et al. Bioessays. 2024 Jul 29:e2400059. doi: 10.1002/bies.202400059. Online ahead of print. Bioessays. 2024. PMID: 39073128
Recently, studies on the role of TEs and their dysregulation in cancers have shed light on the transcriptional, transpositional, and regulatory activity of TEs, revealing that the activation of developmental transcriptional programs by TEs may have a role in the dedifferentiation …
Recently, studies on the role of TEs and their dysregulation in cancers have shed light on the transcriptional, transpositional, and regulat …
Venous thromboembolism incidence and association with overall survival in pancreatic cancer: A Finnish nationwide cohort study.
Aaltonen P, Mustonen H, Puolakkainen P, Haglund C, Peltola K, Carpén O, Lassila R, Seppänen H. Aaltonen P, et al. Cancer Med. 2024 Jul;13(14):e70014. doi: 10.1002/cam4.70014. Cancer Med. 2024. PMID: 39041308 Free PMC article.
INTRODUCTION: Pancreatic cancer (PC) is associated with a high risk of venous thromboembolic events (VTEs). ...METHODS: We identified PC patients diagnosed in 2013-2016 from the Finnish Cancer Registry. Data on healthcare visits and death were collected, along with …
INTRODUCTION: Pancreatic cancer (PC) is associated with a high risk of venous thromboembolic events (VTEs). ...METHODS: We identified …
Web-based prognostic tools for oral tongue cancer: An analysis of online predictors.
Wahab A, Bello IO, Alabi RO, Mascitti M, Troiano G, Mauramo M, Coletta RD, Salo T, Almangush A. Wahab A, et al. Oral Dis. 2024 Jul 5. doi: 10.1111/odi.15009. Online ahead of print. Oral Dis. 2024. PMID: 38968173
RESULTS: The tool entitled 'Prediction of risk of Locoregional Recurrences in Early OTSCC' presented an accuracy of 82%. The tool, 'Head & Neck Cancer Outcome Calculator' for 10-year cancer-related mortality had an accuracy 77% and AUC 0.858. The other tool enti …
RESULTS: The tool entitled 'Prediction of risk of Locoregional Recurrences in Early OTSCC' presented an accuracy of 82%. The tool, 'Head &am …
Histopathological risk assessment in multisite epithelial dysplasia: A meta-analysis.
Ferraz DLF, Dos Santos ES, Pedroso CM, Silva BSF, Kujan O, Salo TA, Malki MI, Juteau S, Vargas PA, Lopes MA, Santos-Silva AR. Ferraz DLF, et al. Oral Dis. 2024 Jun 30. doi: 10.1111/odi.15052. Online ahead of print. Oral Dis. 2024. PMID: 38946217 Review.
OBJECTIVE: Histopathological grading of oral epithelial dysplasia (OED) is the current standard for stratifying cancer progression risk but is associated with subjectivity and variability. ...
OBJECTIVE: Histopathological grading of oral epithelial dysplasia (OED) is the current standard for stratifying cancer progression ri …
232 results