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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1891 1
1915 2
1916 1
1929 1
1930 2
1944 1
1948 3
1949 1
1951 3
1954 1
1955 2
1958 2
1960 3
1961 1
1962 3
1963 1
1964 2
1965 2
1966 3
1967 1
1968 7
1969 6
1970 3
1971 3
1972 7
1973 6
1974 8
1975 12
1976 27
1977 18
1978 30
1979 23
1980 32
1981 24
1982 41
1983 33
1984 39
1985 53
1986 40
1987 55
1988 44
1989 66
1990 69
1991 60
1992 66
1993 92
1994 77
1995 88
1996 87
1997 109
1998 113
1999 111
2000 120
2001 149
2002 177
2003 179
2004 237
2005 250
2006 298
2007 299
2008 328
2009 341
2010 406
2011 437
2012 438
2013 468
2014 541
2015 575
2016 635
2017 650
2018 759
2019 817
2020 916
2021 1094
2022 1203
2023 1240
2024 1295
2025 1567
2026 439

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15,822 results

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Page 1
Tolerability of hypertonic injectables.
Wang W. Wang W. Int J Pharm. 2015 Jul 25;490(1-2):308-15. doi: 10.1016/j.ijpharm.2015.05.069. Epub 2015 May 29. Int J Pharm. 2015. PMID: 26027488 Review.
Injectable drug products are ideally developed as isotonic solutions. Often, hypertonic injectables may have to be marketed for a variety of reasons such as product solubilization and stabilization. ...
Injectable drug products are ideally developed as isotonic solutions. Often, hypertonic injectables may have to be marketed fo …
Preservatives and ocular surface disease: A review.
Kahook MY, Rapuano CJ, Messmer EM, Radcliffe NM, Galor A, Baudouin C. Kahook MY, et al. Ocul Surf. 2024 Oct;34:213-224. doi: 10.1016/j.jtos.2024.08.001. Epub 2024 Aug 3. Ocul Surf. 2024. PMID: 39098762 Free article. Review.
In eyes being treated for glaucoma, symptomatic treatment of OSD may provide some relief, but addressing the root cause of the OSD often necessitates reducing or, ideally, eliminating BAK toxicity. Strategies to decrease BAK exposure in patients with glaucoma encompass the …
In eyes being treated for glaucoma, symptomatic treatment of OSD may provide some relief, but addressing the root cause of the OSD often nec …
Hyaluronic acid in the treatment of dry eye disease.
Hynnekleiv L, Magno M, Vernhardsdottir RR, Moschowits E, Tønseth KA, Dartt DA, Vehof J, Utheim TP. Hynnekleiv L, et al. Acta Ophthalmol. 2022 Dec;100(8):844-860. doi: 10.1111/aos.15159. Epub 2022 May 5. Acta Ophthalmol. 2022. PMID: 35514082 Free PMC article. Review.
Two major gaps in the literature have been identified: 1. no study investigated the ideal drop frequency for HA-containing eyedrops, and 2. insufficient evidence was presented to recommend any specific HA formulation over another. ...
Two major gaps in the literature have been identified: 1. no study investigated the ideal drop frequency for HA-containing eyedrops, …
Management of inflammation in dry eye disease: Recommendations from a European panel of experts.
Messmer EM, Ahmad S, Benitez Del Castillo JM, Mrukwa-Kominek E, Rolando M, Vitovska O, Baudouin C; a panel of European dry eye disease experts. Messmer EM, et al. Eur J Ophthalmol. 2023 May;33(3):1294-1307. doi: 10.1177/11206721221141481. Epub 2022 Dec 5. Eur J Ophthalmol. 2023. PMID: 36471573 Free PMC article. Review.
Patient education is required before and during treatment to manage expectations regarding efficacy and tolerability in order to optimise adherence. Follow-up visits are required, ideally at Month 1 and every 3 months thereafter. Topical CsA may be continued indefinitely, …
Patient education is required before and during treatment to manage expectations regarding efficacy and tolerability in order to optimise ad …
Topical cyclosporine A therapy for dry eye syndrome.
de Paiva CS, Pflugfelder SC, Ng SM, Akpek EK. de Paiva CS, et al. Cochrane Database Syst Rev. 2019 Sep 13;9(9):CD010051. doi: 10.1002/14651858.CD010051.pub2. Cochrane Database Syst Rev. 2019. PMID: 31517988 Free PMC article.
Well-planned, long-term, large clinical trials are needed to better assess CsA on long-term dry eye-modifying effects. A core outcome set, which ideally includes both biomarkers and patient-reported outcomes in the field of dry eye, is needed....
Well-planned, long-term, large clinical trials are needed to better assess CsA on long-term dry eye-modifying effects. A core outcome set, w …
Peritoneal dialysis fluids.
Low S, Liew A. Low S, et al. Semin Dial. 2024 Jan-Feb;37(1):10-23. doi: 10.1111/sdi.13063. Epub 2022 Feb 24. Semin Dial. 2024. PMID: 35212029
Developing these fluids to be efficacious in solute clearance and ultrafiltration, with minimal adverse consequences to peritoneal membrane health and systemic effects is a key requirement. Since the first PD fluid produced in 1959, modifications to PD fluids have been mad …
Developing these fluids to be efficacious in solute clearance and ultrafiltration, with minimal adverse consequences to peritoneal me …
Non-ideal solution thermodynamics of cytoplasm.
Ross-Rodriguez LU, Elliott JA, McGann LE. Ross-Rodriguez LU, et al. Biopreserv Biobank. 2012 Oct;10(5):462-71. doi: 10.1089/bio.2012.0027. Biopreserv Biobank. 2012. PMID: 23840923 Free PMC article.
Quantitative description of the non-ideal solution thermodynamics of the cytoplasm of a living mammalian cell is critically necessary in mathematical modeling of cryobiology and desiccation and other fields where the passive osmotic response of a cell plays a role. …
Quantitative description of the non-ideal solution thermodynamics of the cytoplasm of a living mammalian cell is critically ne …
Comparison of non-ideal solution theories for multi-solute solutions in cryobiology and tabulation of required coefficients.
Zielinski MW, McGann LE, Nychka JA, Elliott JA. Zielinski MW, et al. Cryobiology. 2014 Oct;69(2):305-17. doi: 10.1016/j.cryobiol.2014.08.005. Epub 2014 Aug 23. Cryobiology. 2014. PMID: 25158101 Free article.
These two solution theories require fitting to only single-solute data, although they can make predictions in multi-solute solutions. ...A single, consistent set of literature single-solute solution data was used to fit for the required …
These two solution theories require fitting to only single-solute data, although they can make predictions in multi-solute …
Comparison between ideal and nonideal solution models for single-cell cryopreservation protocols.
Saenz J, Toner M, Risco R. Saenz J, et al. J Phys Chem B. 2009 Apr 9;113(14):4853-64. doi: 10.1021/jp807274z. J Phys Chem B. 2009. PMID: 19338369
Models for cell dehydration during a cryopreservation protocol are usually based on the hypothesis of ideal dilute solution. The strong electrolyte character of NaCl makes us revisit these models. ...The conclusion is that, in general, while the application of the …
Models for cell dehydration during a cryopreservation protocol are usually based on the hypothesis of ideal dilute solution. T …
Solution-related in Vitro Dewetting Behavior of Various Daily Disposable Contact Lenses.
Marx S, Baluschev S, Sickenberger W. Marx S, et al. Optom Vis Sci. 2022 Oct 1;99(10):750-757. doi: 10.1097/OPX.0000000000001939. Epub 2022 Sep 16. Optom Vis Sci. 2022. PMID: 36095059 Free PMC article.
In vitro dewetting data of the same CL materials soaked in saline solution and artificial tear solution (ATS) were measured to determine additional dewetting characteristics. ...Slower dewetting was detected for all materials when measured out of their specific blis …
In vitro dewetting data of the same CL materials soaked in saline solution and artificial tear solution (ATS) were measured to …
15,822 results
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