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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1994 2
1995 5
1996 3
1997 4
1998 2
1999 1
2000 8
2001 10
2002 13
2003 6
2004 11
2005 8
2006 7
2007 6
2008 11
2009 11
2010 8
2011 10
2012 14
2013 9
2014 13
2015 20
2016 26
2017 17
2018 25
2019 32
2020 20
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288 results
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Page 1
Microglia after Seizures and in Epilepsy.
Hiragi T, Ikegaya Y, Koyama R. Hiragi T, et al. Among authors: ikegaya y. Cells. 2018 Mar 28;7(4):26. doi: 10.3390/cells7040026. Cells. 2018. PMID: 29597334 Free PMC article. Review.
Microglia are the resident immune cells in the brain that constitute the brain's innate immune system. Recent studies have revealed various functions of microglia in the development and maintenance of the central nervous system (CNS) in both health and disease. ...
Microglia are the resident immune cells in the brain that constitute the brain's innate immune system. Recent studies have revealed v …
Synaptic Pruning by Microglia in Epilepsy.
Andoh M, Ikegaya Y, Koyama R. Andoh M, et al. Among authors: ikegaya y. J Clin Med. 2019 Dec 9;8(12):2170. doi: 10.3390/jcm8122170. J Clin Med. 2019. PMID: 31818018 Free PMC article. Review.
In epilepsy, the synaptic E/I balance tips toward excitation; thus, most of the existing epileptic remedies have focused on how to directly suppress the activity of neurons. However, because as many as 30% of patients with epilepsy are drug resistant, the discovery of new …
In epilepsy, the synaptic E/I balance tips toward excitation; thus, most of the existing epileptic remedies have focused on how to directly …
Hippocampal ripples down-regulate synapses.
Norimoto H, Makino K, Gao M, Shikano Y, Okamoto K, Ishikawa T, Sasaki T, Hioki H, Fujisawa S, Ikegaya Y. Norimoto H, et al. Among authors: ikegaya y. Science. 2018 Mar 30;359(6383):1524-1527. doi: 10.1126/science.aao0702. Epub 2018 Feb 8. Science. 2018. PMID: 29439023
Thus, our findings are consistent with the role of slow-wave states in refining memory engrams by reducing recent memory-irrelevant neuronal activity and suggest a previously unrecognized function for sharp-wave ripples....
Thus, our findings are consistent with the role of slow-wave states in refining memory engrams by reducing recent memory-irrelevant neuro
Microglia as possible therapeutic targets for autism spectrum disorders.
Andoh M, Ikegaya Y, Koyama R. Andoh M, et al. Among authors: ikegaya y. Prog Mol Biol Transl Sci. 2019;167:223-245. doi: 10.1016/bs.pmbts.2019.06.012. Epub 2019 Jul 11. Prog Mol Biol Transl Sci. 2019. PMID: 31601405 Review.
Malfunctions of the nervous and immune systems are now recognized to be fundamental causes of autism spectrum disorders (ASDs). Studies have suggested that the brain's resident immune cells, microglia are possible key players in ASDs. ...
Malfunctions of the nervous and immune systems are now recognized to be fundamental causes of autism spectrum disorders (ASDs). Studies have …
Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation.
Andoh M, Shibata K, Okamoto K, Onodera J, Morishita K, Miura Y, Ikegaya Y, Koyama R. Andoh M, et al. Among authors: ikegaya y. Cell Rep. 2019 Jun 4;27(10):2817-2825.e5. doi: 10.1016/j.celrep.2019.05.015. Cell Rep. 2019. PMID: 31167129 Free article.
The Astrocytic cAMP Pathway in Health and Disease.
Zhou Z, Ikegaya Y, Koyama R. Zhou Z, et al. Among authors: ikegaya y. Int J Mol Sci. 2019 Feb 12;20(3):779. doi: 10.3390/ijms20030779. Int J Mol Sci. 2019. PMID: 30759771 Free PMC article. Review.
Neonatal Seizure Models to Study Epileptogenesis.
Kasahara Y, Ikegaya Y, Koyama R. Kasahara Y, et al. Among authors: ikegaya y. Front Pharmacol. 2018 Apr 18;9:385. doi: 10.3389/fphar.2018.00385. eCollection 2018. Front Pharmacol. 2018. PMID: 29720941 Free PMC article. Review.
Cortical and subcortical responses to biological motion.
Chang DHF, Ban H, Ikegaya Y, Fujita I, Troje NF. Chang DHF, et al. Among authors: ikegaya y. Neuroimage. 2018 Jul 1;174:87-96. doi: 10.1016/j.neuroimage.2018.03.013. Epub 2018 Mar 8. Neuroimage. 2018. PMID: 29524623
[Learning Paradigms for the Promotion of Memory, and Their Underlying Principles].
Makino K, Ikegaya Y. Makino K, et al. Among authors: ikegaya y. Brain Nerve. 2018 Jul;70(7):821-828. doi: 10.11477/mf.1416201083. Brain Nerve. 2018. PMID: 29997278 Review. Japanese.
Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories.
Nomura H, Mizuta H, Norimoto H, Masuda F, Miura Y, Kubo A, Kojima H, Ashizuka A, Matsukawa N, Baraki Z, Hitora-Imamura N, Nakayama D, Ishikawa T, Okada M, Orita K, Saito R, Yamauchi N, Sano Y, Kusuhara H, Minami M, Takahashi H, Ikegaya Y. Nomura H, et al. Among authors: ikegaya y. Biol Psychiatry. 2019 Aug 1;86(3):230-239. doi: 10.1016/j.biopsych.2018.11.009. Epub 2019 Jan 8. Biol Psychiatry. 2019. PMID: 30635130 Free article. Clinical Trial.
The memory recovery was mediated by the disinhibition of histamine release in the perirhinal cortex, which activated the histamine H(2) receptor. Histamine depolarized perirhinal cortex neurons, enhanced their spontaneous activity, and facilitated the reactivation of behav …
The memory recovery was mediated by the disinhibition of histamine release in the perirhinal cortex, which activated the histamine H(2) rece …
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