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Year Number of Results
1987 1
1988 1
1992 2
1993 2
1994 1
1995 1
1996 1
1997 4
1998 3
1999 3
2000 1
2002 1
2003 2
2004 4
2005 1
2006 4
2007 6
2008 7
2009 7
2010 5
2011 7
2012 7
2013 4
2014 4
2015 5
2016 4
2017 9
2018 9
2019 18
2020 17
2021 19
2022 17
2023 15
2024 4

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171 results

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Page 1
Mitochondrial extracellular vesicles, autoimmunity and myocarditis.
Di Florio DN, Beetler DJ, McCabe EJ, Sin J, Ikezu T, Fairweather D. Di Florio DN, et al. Front Immunol. 2024 Mar 14;15:1374796. doi: 10.3389/fimmu.2024.1374796. eCollection 2024. Front Immunol. 2024. PMID: 38550582 Free PMC article. Review.
Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease.
Raulin AC, Doss SV, Heckman MG, Craver EC, Li Z, Ikezu TC, Sekiya H, Liu CC, Martens YA, Rosenberg CL, Kuchenbecker LA, DeTure M, Reichard RR, Nguyen AT, Constantopoulos E, Larsen RA, Kounaves EK, Murray ME, Dickson DW, Petersen RC, Bu G, Kanekiyo T. Raulin AC, et al. Acta Neuropathol Commun. 2024 Feb 9;12(1):25. doi: 10.1186/s40478-024-01731-0. Acta Neuropathol Commun. 2024. PMID: 38336940 Free PMC article.
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW. Welsh JA, et al. J Extracell Vesicles. 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404. J Extracell Vesicles. 2024. PMID: 38326288 Free PMC article.
Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies.
Sandau US, Magaña SM, Costa J, Nolan JP, Ikezu T, Vella LJ, Jackson HK, Moreira LR, Palacio PL, Hill AF, Quinn JF, Van Keuren-Jensen KR, McFarland TJ, Palade J, Sribnick EA, Su H, Vekrellis K, Coyle B, Yang Y, Falcón-Perez JM, Nieuwland R, Saugstad JA; International Society for Extracellular Vesicles Cerebrospinal Fluid Task Force. Sandau US, et al. J Extracell Vesicles. 2024 Jan;13(1):e12397. doi: 10.1002/jev2.12397. J Extracell Vesicles. 2024. PMID: 38158550 Free PMC article. Review.
Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Liu CC, Wang N, Chen Y, Inoue Y, Shue F, Ren Y, Wang M, Qiao W, Ikezu TC, Li Z, Zhao J, Martens Y, Doss SV, Rosenberg CL, Jeevaratnam S, Jia L, Raulin AC, Qi F, Zhu Y, Alnobani A, Knight J, Chen Y, Linares C, Kurti A, Fryer JD, Zhang B, Wu LJ, Kim BYS, Bu G. Liu CC, et al. Nat Immunol. 2023 Nov;24(11):1854-1866. doi: 10.1038/s41590-023-01640-9. Epub 2023 Oct 19. Nat Immunol. 2023. PMID: 37857825
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.
Yin Z, Rosenzweig N, Kleemann KL, Zhang X, Brandão W, Margeta MA, Schroeder C, Sivanathan KN, Silveira S, Gauthier C, Mallah D, Pitts KM, Durao A, Herron S, Shorey H, Cheng Y, Barry JL, Krishnan RK, Wakelin S, Rhee J, Yung A, Aronchik M, Wang C, Jain N, Bao X, Gerrits E, Brouwer N, Deik A, Tenen DG, Ikezu T, Santander NG, McKinsey GL, Baufeld C, Sheppard D, Krasemann S, Nowarski R, Eggen BJL, Clish C, Tanzi RE, Madore C, Arnold TD, Holtzman DM, Butovsky O. Yin Z, et al. Nat Immunol. 2023 Nov;24(11):1839-1853. doi: 10.1038/s41590-023-01627-6. Epub 2023 Sep 25. Nat Immunol. 2023. PMID: 37749326
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer's disease.
Yin Z, Herron S, Silveira S, Kleemann K, Gauthier C, Mallah D, Cheng Y, Margeta MA, Pitts KM, Barry JL, Subramanian A, Shorey H, Brandao W, Durao A, Delpech JC, Madore C, Jedrychowski M, Ajay AK, Murugaiyan G, Hersh SW, Ikezu S, Ikezu T, Butovsky O. Yin Z, et al. Nat Neurosci. 2023 Jul;26(7):1196-1207. doi: 10.1038/s41593-023-01355-y. Epub 2023 Jun 8. Nat Neurosci. 2023. PMID: 37291336
Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology.
Qiao W, Chen Y, Zhong J, Madden BJ, Charlesworth CM, Martens YA, Liu CC, Knight J, Ikezu TC, Kurti A, Zhu Y, Meneses A, Rosenberg CL, Kuchenbecker LA, Vanmaele LK, Li F, Chen K, Shue F, Dacquel MV, Fryer J, Pandey A, Zhao N, Bu G. Qiao W, et al. Mol Neurodegener. 2023 Apr 28;18(1):28. doi: 10.1186/s13024-023-00603-w. Mol Neurodegener. 2023. PMID: 37118783 Free PMC article. No abstract available.
INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model.
Iguchi A, Takatori S, Kimura S, Muneto H, Wang K, Etani H, Ito G, Sato H, Hori Y, Sasaki J, Saito T, Saido TC, Ikezu T, Takai T, Sasaki T, Tomita T. Iguchi A, et al. iScience. 2023 Mar 13;26(4):106375. doi: 10.1016/j.isci.2023.106375. eCollection 2023 Apr 21. iScience. 2023. PMID: 37035000 Free PMC article.
Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology.
Qiao W, Chen Y, Zhong J, Madden BJ, Charlesworth CM, Martens YA, Liu CC, Knight J, Ikezu TC, Kurti A, Zhu Y, Meneses A, Rosenberg CL, Kuchenbecker LA, Vanmaele LK, Li F, Chen K, Shue F, Dacquel MV, Fryer J, Pandey A, Zhao N, Bu G. Qiao W, et al. Mol Neurodegener. 2023 Jan 31;18(1):8. doi: 10.1186/s13024-023-00599-3. Mol Neurodegener. 2023. PMID: 36721205 Free PMC article.
APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology.
Meneses AD, Koga S, Li Z, O'Leary J, Li F, Chen K, Murakami A, Qiao W, Kurti A, Heckman MG, White L, Xie M, Chen Y, Finch NA, Lim MJ, Delenclos M, DeTure MA, Linares C, Martin NB, Ikezu TC, van Blitterswijk MM, Wu LJ, McLean PJ, Rademakers R, Ross OA, Dickson DW, Bu G, Zhao N. Meneses AD, et al. Ann Neurol. 2023 Apr;93(4):830-843. doi: 10.1002/ana.26580. Epub 2023 Jan 10. Ann Neurol. 2023. PMID: 36546684 Free PMC article.
Extracellular vesicles as personalized medicine.
Beetler DJ, Di Florio DN, Bruno KA, Ikezu T, March KL, Cooper LT Jr, Wolfram J, Fairweather D. Beetler DJ, et al. Mol Aspects Med. 2023 Jun;91:101155. doi: 10.1016/j.mam.2022.101155. Epub 2022 Nov 28. Mol Aspects Med. 2023. PMID: 36456416 Free PMC article. Review.
Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.
Zhao N, Qiao W, Li F, Ren Y, Zheng J, Martens YA, Wang X, Li L, Liu CC, Chen K, Zhu Y, Ikezu TC, Li Z, Meneses AD, Jin Y, Knight JA, Chen Y, Bastea L, Linares C, Sonustun B, Job L, Smith ML, Xie M, Liu YU, Umpierre AD, Haruwaka K, Quicksall ZS, Storz P, Asmann YW, Wu LJ, Bu G. Zhao N, et al. J Exp Med. 2022 Dec 5;219(12):e20212479. doi: 10.1084/jem.20212479. Epub 2022 Sep 15. J Exp Med. 2022. PMID: 36107206 Free PMC article.
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia.
Shi H, Yin Z, Koronyo Y, Fuchs DT, Sheyn J, Davis MR, Wilson JW, Margeta MA, Pitts KM, Herron S, Ikezu S, Ikezu T, Graham SL, Gupta VK, Black KL, Mirzaei M, Butovsky O, Koronyo-Hamaoui M. Shi H, et al. Acta Neuropathol Commun. 2022 Sep 8;10(1):136. doi: 10.1186/s40478-022-01439-z. Acta Neuropathol Commun. 2022. PMID: 36076283 Free PMC article.
Publisher Correction: Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress.
Okusha Y, Lang BJ, Murshid A, Borges TJ, Holton KM, Clark-Matott J, Doshi S, Ikezu T, Calderwood SK. Okusha Y, et al. Cell Stress Chaperones. 2022 Sep;27(5):479-483. doi: 10.1007/s12192-022-01285-x. Cell Stress Chaperones. 2022. PMID: 35831741 Free PMC article. No abstract available.
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
Jin Y, Li F, Sonoustoun B, Kondru NC, Martens YA, Qiao W, Heckman MG, Ikezu TC, Li Z, Burgess JD, Amerna D, O'Leary J, DeTure MA, Zhao J, McLean PJ, Dickson DW, Ross OA, Bu G, Zhao N. Jin Y, et al. Acta Neuropathol. 2022 Jun;143(6):641-662. doi: 10.1007/s00401-022-02421-8. Epub 2022 Apr 26. Acta Neuropathol. 2022. PMID: 35471463 Free PMC article.
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W; Alzheimer's Disease Genetics Consortium; Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Jun GR, et al. Alzheimers Dement. 2022 Nov;18(11):2042-2054. doi: 10.1002/alz.12607. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35142023 Free PMC article.
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.
Liu CC, Murray ME, Li X, Zhao N, Wang N, Heckman MG, Shue F, Martens Y, Li Y, Raulin AC, Rosenberg CL, Doss SV, Zhao J, Wren MC, Jia L, Ren Y, Ikezu TC, Lu W, Fu Y, Caulfield T, Trottier ZA, Knight J, Chen Y, Linares C, Wang X, Kurti A, Asmann YW, Wszolek ZK, Smith GE, Vemuri P, Kantarci K, Knopman DS, Lowe VJ, Jack CR Jr, Parisi JE, Ferman TJ, Boeve BF, Graff-Radford NR, Petersen RC, Younkin SG, Fryer JD, Wang H, Han X, Frieden C, Dickson DW, Ross OA, Bu G. Liu CC, et al. Sci Transl Med. 2021 Sep 29;13(613):eabc9375. doi: 10.1126/scitranslmed.abc9375. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586832 Free PMC article.
Morphological characteristics of the Lisfranc ligament.
Suzuki Y, Edama M, Kaneko F, Ikezu M, Matsuzawa K, Hirabayashi R, Kageyama I. Suzuki Y, et al. J Foot Ankle Res. 2020 Jul 16;13(1):46. doi: 10.1186/s13047-020-00412-0. J Foot Ankle Res. 2020. PMID: 32677989 Free PMC article.
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses.
Podvin S, Jones A, Liu Q, Aulston B, Ransom L, Ames J, Shen G, Lietz CB, Jiang Z, O'Donoghue AJ, Winston C, Ikezu T, Rissman RA, Yuan S, Hook V. Podvin S, et al. Mol Cell Proteomics. 2020 Jun;19(6):1017-1034. doi: 10.1074/mcp.RA120.002079. Epub 2020 Apr 15. Mol Cell Proteomics. 2020. PMID: 32295833 Free PMC article.
Tau Secretion.
Ruan Z, Ikezu T. Ruan Z, et al. Adv Exp Med Biol. 2019;1184:123-134. doi: 10.1007/978-981-32-9358-8_11. Adv Exp Med Biol. 2019. PMID: 32096034 Review.
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities.
Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, Botros MB, Madore C, Chao PH, Desani A, Manimaran S, Kalavai SV, Johnson WE, Butovsky O, Medalla M, Luebke JI, Ikezu T. Ikezu S, et al. Mol Psychiatry. 2021 Jun;26(6):1808-1831. doi: 10.1038/s41380-020-0671-2. Epub 2020 Feb 18. Mol Psychiatry. 2021. PMID: 32071385 Free PMC article.
Morphological features of the cervical ligament.
Edama M, Takabayashi T, Inai T, Hirabayashi R, Ikezu M, Kaneko F, Matsuzawa K, Kageyama I. Edama M, et al. Surg Radiol Anat. 2020 Feb;42(2):215-218. doi: 10.1007/s00276-019-02364-y. Epub 2019 Nov 1. Surg Radiol Anat. 2020. PMID: 31676928
Morphological features of the posterior intermalleolar ligament.
Edama M, Takabayashi T, Inai T, Hirabayashi R, Ikezu M, Kaneko F, Kanta M, Kageyama I. Edama M, et al. Surg Radiol Anat. 2019 Dec;41(12):1441-1443. doi: 10.1007/s00276-019-02295-8. Epub 2019 Jul 23. Surg Radiol Anat. 2019. PMID: 31338536
Relationships between differences in the number of fiber bundles of the anterior talofibular ligament and differences in the angle of the calcaneofibular ligament and their effects on ankle-braking function.
Edama M, Takabayashi T, Inai T, Kikumoto T, Ito W, Nakamura E, Hirabayashi R, Ikezu M, Kaneko F, Kageyama I. Edama M, et al. Surg Radiol Anat. 2019 Jun;41(6):675-679. doi: 10.1007/s00276-019-02239-2. Epub 2019 Apr 16. Surg Radiol Anat. 2019. PMID: 30993419
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönit… See abstract for full author list ➔ Théry C, et al. J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018. J Extracell Vesicles. 2018. PMID: 30637094 Free PMC article.
TIA1 regulates the generation and response to toxic tau oligomers.
Jiang L, Ash PEA, Maziuk BF, Ballance HI, Boudeau S, Abdullatif AA, Orlando M, Petrucelli L, Ikezu T, Wolozin B. Jiang L, et al. Acta Neuropathol. 2019 Feb;137(2):259-277. doi: 10.1007/s00401-018-1937-5. Epub 2018 Nov 21. Acta Neuropathol. 2019. PMID: 30465259 Free PMC article.
Morphological features of the bifurcated ligament.
Edama M, Ikezu M, Kaneko F, Kikumoto T, Takabayashi T, Hirabayashi R, Inai T, Kageyama I. Edama M, et al. Surg Radiol Anat. 2019 Jan;41(1):3-7. doi: 10.1007/s00276-018-2089-y. Epub 2018 Aug 20. Surg Radiol Anat. 2019. PMID: 30128896
Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.
Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebke J, Bryant CD, Wolozin B. Apicco DJ, et al. Nat Neurosci. 2018 Jan;21(1):72-80. doi: 10.1038/s41593-017-0022-z. Epub 2017 Nov 20. Nat Neurosci. 2018. PMID: 29273772 Free PMC article.
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O. Krasemann S, et al. Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008. Immunity. 2017. PMID: 28930663 Free PMC article.
Neuroimmune Pharmacology, 2nd Edition - A Perspective.
Gelbard HA. Gelbard HA. J Neuroimmune Pharmacol. 2017 Jun;12(2):211-212. doi: 10.1007/s11481-017-9738-5. Epub 2017 Mar 23. J Neuroimmune Pharmacol. 2017. PMID: 28337573 Review.
It has been almost nine years since the 1st edition of Neuroimmune Pharmacology was published on May 23rd, 2008. The 2nd edition of Neuroimmune Pharmacology by Ikezu and Gendelman (Editors) with Przedborski, Masliah and Cosentino (Associate Editors) manages to fulfill two …
It has been almost nine years since the 1st edition of Neuroimmune Pharmacology was published on May 23rd, 2008. The 2nd edition of Neuroimm …
Occurrence of Crohn's disease with Parkinson's disease.
Fujioka S, Curry SE, Kennelly KD, Tacik P, Heckman MG, Tsuboi Y, Strongosky AJ, van Gerpen JA, Uitti RJ, Ross OA, Ikezu T, Wszolek ZK. Fujioka S, et al. Parkinsonism Relat Disord. 2017 Apr;37:116-117. doi: 10.1016/j.parkreldis.2017.01.013. Epub 2017 Feb 10. Parkinsonism Relat Disord. 2017. PMID: 28215729 Free PMC article.
Tsuneya Ikezu.
[No authors listed] [No authors listed] Lancet Neurol. 2017 Jan;16(1):31. doi: 10.1016/S1474-4422(16)30353-2. Lancet Neurol. 2017. PMID: 27979352 No abstract available.
Syk and Yea Shall Find.
Wolozin B, Ikezu T. Wolozin B, et al. EBioMedicine. 2015 Nov 10;2(11):1590-1. doi: 10.1016/j.ebiom.2015.11.012. eCollection 2015 Nov. EBioMedicine. 2015. PMID: 26870779 Free PMC article. No abstract available.
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. Jun G, et al. Ann Neurol. 2014 Sep;76(3):379-92. doi: 10.1002/ana.24219. Epub 2014 Jul 29. Ann Neurol. 2014. PMID: 25043464 Free PMC article.
Tau-tubulin kinase.
Ikezu S, Ikezu T. Ikezu S, et al. Front Mol Neurosci. 2014 Apr 28;7:33. doi: 10.3389/fnmol.2014.00033. eCollection 2014. Front Mol Neurosci. 2014. PMID: 24808823 Free PMC article. Review.
Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.
Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, Lemere CA. Frost JL, et al. Am J Pathol. 2013 Aug;183(2):369-81. doi: 10.1016/j.ajpath.2013.05.005. Epub 2013 Jun 7. Am J Pathol. 2013. PMID: 23747948 Free PMC article.
The spectrum of disease in chronic traumatic encephalopathy.
McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, Abraham CR, Ikezu T, Reichard RR, Wolozin BL, Budson AE, Goldstein LE, Kowall NW, Cantu RC. McKee AC, et al. Brain. 2013 Jan;136(Pt 1):43-64. doi: 10.1093/brain/aws307. Epub 2012 Dec 2. Brain. 2013. PMID: 23208308 Free PMC article.
Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.
Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC. Goldstein LE, et al. Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716. Sci Transl Med. 2012. PMID: 22593173 Free PMC article.
Practicable group testing method to evaluate weight/weight GMO content in maize grains.
Mano J, Yanaka Y, Ikezu Y, Onishi M, Futo S, Minegishi Y, Ninomiya K, Yotsuyanagi Y, Spiegelhalter F, Akiyama H, Teshima R, Hino A, Naito S, Koiwa T, Takabatake R, Furui S, Kitta K. Mano J, et al. J Agric Food Chem. 2011 Jul 13;59(13):6856-63. doi: 10.1021/jf200212v. Epub 2011 Jun 7. J Agric Food Chem. 2011. PMID: 21604714
Neuroimmune pharmacology as a sub-discipline of medical neuroscience in the medical school curriculum.
Freilich RW, Ikezu T. Freilich RW, et al. J Neuroimmune Pharmacol. 2011 Mar;6(1):41-56. doi: 10.1007/s11481-010-9250-7. Epub 2010 Nov 20. J Neuroimmune Pharmacol. 2011. PMID: 21103946 Free PMC article. Review.
The emerging field of neuroimmune pharmacology (NIP) is the confluence of three distinct disciplines: neuroscience, immunology, and pharmacology (Gendelman and Ikezu 2008). NIP was born from the realization that inflammation within the central nervous system (CNS) plays a …
The emerging field of neuroimmune pharmacology (NIP) is the confluence of three distinct disciplines: neuroscience, immunology, and pharmaco …
The neuropathogenesis of HIV-1 infection.
Buescher JL, Gross S, Gendelman HE, Ikezu T. Buescher JL, et al. Handb Clin Neurol. 2007;85:45-67. doi: 10.1016/S0072-9752(07)85004-4. Handb Clin Neurol. 2007. PMID: 18808975 No abstract available.
Analysis of Galpha protein recognition profiles of angiotensin II receptors using chimeric Galpha proteins.
Sasamura H, Mifune M, Nakaya H, Amemiya T, Hiraki T, Nishimoto I, Saruta T. Sasamura H, et al. Mol Cell Endocrinol. 2000 Dec 22;170(1-2):113-21. doi: 10.1016/s0303-7207(00)00333-6. Mol Cell Endocrinol. 2000. PMID: 11162895
The aim of this study was to analyze the ability of type 1 (AT1) and type 2 (AT2) angiotensin receptors to recognize the receptor coupling regions of Galpha proteins using our previously described technique (Ikezu, T., Okamoto, T., Komatsuzaki, K., Matsui, T., Martyn, J.A. …
The aim of this study was to analyze the ability of type 1 (AT1) and type 2 (AT2) angiotensin receptors to recognize the receptor coupling r …
Potential CRE suppression by familial Alzheimer's mutants of APP independent of adenylyl cyclase regulation.
Giambarella U, Murayama Y, Ikezu T, Fujita T, Nishimoto I. Giambarella U, et al. FEBS Lett. 1997 Jul 21;412(1):97-101. doi: 10.1016/s0014-5793(97)00753-9. FEBS Lett. 1997. PMID: 9257698 Free article.
It has been found that expression of each FAD mutant suppresses the transcriptional activity of the cAMP response element CRE in a G alpha(o)-dependent manner in a COS cell clone NK1 [Ikezu et al. (1996) EMBO J. 15, 2468-2475]. Here we show that adenylyl cyclase (AC) inhib …
It has been found that expression of each FAD mutant suppresses the transcriptional activity of the cAMP response element CRE in a G alpha(o …