Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1989 1
1991 1
1994 1
2016 1
2017 3
2018 5
2019 5
2020 2
2021 5
2022 3
2023 2
2024 6
2025 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

31 results

Results by year

Filters applied: . Clear all
Page 1
Unlocking the Ilex guayusa Potential: Volatile Composition, Antioxidant, Antidiabetic, and Hemolytic Activities, with In Silico Molecular Docking and ADMET Analysis of Hydroethanolic Extracts.
de Los Monteros-Silva NE, Martínez-Palacios K, Jiménez AM, Ochoa-Ocampo M, Garzón T, Carrillo-Vásconez T, Radice M, Yánez EV, Rea-Martínez J, Niño-Ruiz Z, Dieguez-Santana K, Mogollón NGS. de Los Monteros-Silva NE, et al. Molecules. 2025 Sep 25;30(19):3885. doi: 10.3390/molecules30193885. Molecules. 2025. PMID: 41097306 Free PMC article.
This work studies the underexplored potential of Ilex guayusa and demonstrates the influence of geographical (locations: A, B, C) and ontogenetic (young: 0; old: 2) factors on its biochemical profile. ...
This work studies the underexplored potential of Ilex guayusa and demonstrates the influence of geographical (locations: A, B, …
Guayusa (Ilex guayusa Loes.) Ancestral Plant of Ecuador: History, Traditional Uses, Chemistry, Biological Activity, and Potential Industrial Uses.
Noriega P, Moreno E, Falcón A, Quishpe V, Noriega PDC. Noriega P, et al. Molecules. 2025 Jul 2;30(13):2837. doi: 10.3390/molecules30132837. Molecules. 2025. PMID: 40649351 Free PMC article. Review.
One of the medicinal plants used in Ecuador that has the best prospects for industrialization is guayusa (Ilex guayusa Loes.). This review shows the potential of the species, analyzing the ethnobotanical aspects, ancestral uses, secondary metabolites, and res …
One of the medicinal plants used in Ecuador that has the best prospects for industrialization is guayusa (Ilex guayusa
Ilex Guayusa Tea Improves Glycaemia and Autonomic Modulation in Female Streptozotocin-Induced Diabetic Rats.
Mello TC, Dias DDS, Bernardes N, Araujo AAD, Dos Santos CP, Llesuy S, De Angelis K, Stoyell-Conti FF. Mello TC, et al. Pharmaceuticals (Basel). 2025 Feb 24;18(3):316. doi: 10.3390/ph18030316. Pharmaceuticals (Basel). 2025. PMID: 40143095 Free PMC article.
Thus, this study evaluated the effects of Ilex guayusa tea on cardiovascular, autonomic, metabolic, and oxidative stress parameters in diabetic rats, as well as its antioxidant and phytochemical properties. Methods: Thirteen female Wistar rats were divided into two …
Thus, this study evaluated the effects of Ilex guayusa tea on cardiovascular, autonomic, metabolic, and oxidative stress param …
Antioxidant Capacity, Phenolic Compounds, and Other Constituents of Cold and Hot Yerba Mate (Ilex paraguariensis) Infusions.
Płatkiewicz J, Okołowicz D, Frankowski R, Grześkowiak T, Jeszka-Skowron M, Zgoła-Grześkowiak A. Płatkiewicz J, et al. Antioxidants (Basel). 2024 Nov 29;13(12):1467. doi: 10.3390/antiox13121467. Antioxidants (Basel). 2024. PMID: 39765796 Free PMC article.
Yerba mate beverage is prepared from Ilex paraguariensis grown in South America, and its popularity still is increasing. The aim of this study was to show the differences in the content of antioxidant compounds between hot- and cold-prepared mate beverages. ...In both cond …
Yerba mate beverage is prepared from Ilex paraguariensis grown in South America, and its popularity still is increasing. The aim of t …
Green Processing of Ilex guayusa: Antioxidant Concentration and Caffeine Reduction Using Encapsulation by Supercritical Antisolvent Process.
Meneses MÁ, Guzmán J, Cabrera J, Magallanes J, Valarezo E, Guamán-Balcázar MDC. Meneses MÁ, et al. Molecules. 2024 Nov 11;29(22):5309. doi: 10.3390/molecules29225309. Molecules. 2024. PMID: 39598698 Free PMC article.
This study investigated the valorization of Ilex guayusa leaves by producing a low-caffeine, antioxidant-rich product through the supercritical antisolvent extraction (SAE) process. ...The SAE treatments were conducted using an ethanolic extract of guayusa le …
This study investigated the valorization of Ilex guayusa leaves by producing a low-caffeine, antioxidant-rich product through …
Acute, dose-response effects of guayusa leaf extract on mood, cognitive and motor-cognitive performance, and blood pressure, heart rate, and ventricular repolarization.
Helwig NJ, Schwager LE, Berry AC, Zucker AC, Venenga JS, Sterbenz SC, Jenkins NDM. Helwig NJ, et al. J Int Soc Sports Nutr. 2024 Dec;21(1):2379424. doi: 10.1080/15502783.2024.2379424. Epub 2024 Jul 16. J Int Soc Sports Nutr. 2024. PMID: 39014963 Free PMC article. Clinical Trial.
PURPOSE: We conducted a randomized, double-blind, placebo-controlled crossover trial in young adults to examine the dose-dependent (600 mg versus 1200 mg), acute effects of consumption of an Ilex guayusa tea extract (GLE) on mood, cognitive and motor-cognitive perfo …
PURPOSE: We conducted a randomized, double-blind, placebo-controlled crossover trial in young adults to examine the dose-dependent (600 mg v …
Evaluation of Ilex guayusa and Piper marginatum Extract Cytotoxicity on Human Dental Pulp Mesenchymal Stem Cells.
Sequeda-Castañeda LG, Suárez-Carvajal LF, Téllez-Corral MA, Gutiérrez-Prieto SJ, Méndez-Pinzón HA. Sequeda-Castañeda LG, et al. Dent J (Basel). 2024 Jun 20;12(6):189. doi: 10.3390/dj12060189. Dent J (Basel). 2024. PMID: 38920890 Free PMC article.
Our recent studies have shown that extracts from Colombian native plants, Ilex guayusa and Piper marginatum, deposit mineral ions such as phosphate and orthophosphate into the dental enamel structure; however, it is unknown whether these extracts produce toxic effec …
Our recent studies have shown that extracts from Colombian native plants, Ilex guayusa and Piper marginatum, deposit mineral i …
Exploring the Impact of Infusion Parameters and In Vitro Digestion on the Phenolic Profile and Antioxidant Capacity of Guayusa (Ilex guayusa Loes.) Tea Using Liquid Chromatography, Diode Array Detection, and Electrospray Ionization Tandem Mass Spectrometry.
Kelebek H, Sasmaz HK, Aksay O, Selli S, Kahraman O, Fields C. Kelebek H, et al. Foods. 2024 Feb 24;13(5):694. doi: 10.3390/foods13050694. Foods. 2024. PMID: 38472807 Free PMC article.
Guayusa tea is derived from the leaves of the Ilex guayusa Loes. plant, which is native to the Amazon rainforest. Beyond its pleasant sensory properties, Guayusa tea is rich in antioxidants, phenolics, and minerals. In this study, the effects of infusi
Guayusa tea is derived from the leaves of the Ilex guayusa Loes. plant, which is native to the Amazon rainforest. Beyon
Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion's Mane Extracts on Cognitive Performance.
La Monica MB, Raub B, Ziegenfuss EJ, Hartshorn S, Grdic J, Gustat A, Sandrock J, Ziegenfuss TN. La Monica MB, et al. Nutrients. 2023 Dec 6;15(24):5018. doi: 10.3390/nu15245018. Nutrients. 2023. PMID: 38140277 Free PMC article. Clinical Trial.
The aim of this study was to assess the effects of guayusa extract and Nordic Lion's Mane (LM) on cognition. Using a randomized, double-blind, placebo-controlled, crossover design, we examined the effects of a single dose of 650 mg guayusa extract (AMT: AmaTea() Max …
The aim of this study was to assess the effects of guayusa extract and Nordic Lion's Mane (LM) on cognition. Using a randomized, doub …
31 results