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The m(6)A methyltransferase Ime4 and mitochondrial functions in yeast.
Yadav PK, Rajasekharan R. Yadav PK, et al. Curr Genet. 2018 Apr;64(2):353-357. doi: 10.1007/s00294-017-0758-8. Epub 2017 Oct 3. Curr Genet. 2018. PMID: 28975387 Review.
As of now there are no reports on the role of Ime4 in mitochondrial biology. Here we report the important role played by Ime4 in the mitochondrial morphology and functions in Saccharomyces cerevisiae. ...IME4 gene deletion causes mitochondrial d …
As of now there are no reports on the role of Ime4 in mitochondrial biology. Here we report the important role played by Ime4 …
The role of yeast m(6)A methyltransferase in peroxisomal fatty acid oxidation.
Yadav PK, Rajvanshi PK, Rajasekharan R. Yadav PK, et al. Curr Genet. 2018 Apr;64(2):417-422. doi: 10.1007/s00294-017-0769-5. Epub 2017 Oct 17. Curr Genet. 2018. PMID: 29043484 Review.
Therefore, we hypothesized a possible role of Ime4 in the peroxisomal functions. There is no report on the role of Ime4 in peroxisomal biology. Here, we report that IME4 gene deletion causes peroxisomal dysfunction under stationary-phase conditions in Sacc …
Therefore, we hypothesized a possible role of Ime4 in the peroxisomal functions. There is no report on the role of Ime4 in per …
The m(6)A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells.
Yadav PK, Rajasekharan R. Yadav PK, et al. J Biol Chem. 2017 Aug 18;292(33):13727-13744. doi: 10.1074/jbc.M117.783761. Epub 2017 Jun 27. J Biol Chem. 2017. PMID: 28655762 Free PMC article.
N(6)-Methyladenosine (m(6)A) is among the most common modifications in eukaryotic mRNA. The role of yeast m(6)A methyltransferase, Ime4, in meiosis and sporulation in diploid strains is very well studied, but its role in haploid strains has remained unknown. Here, w …
N(6)-Methyladenosine (m(6)A) is among the most common modifications in eukaryotic mRNA. The role of yeast m(6)A methyltransferase, …
IME4, a gene that mediates MAT and nutritional control of meiosis in Saccharomyces cerevisiae.
Shah JC, Clancy MJ. Shah JC, et al. Mol Cell Biol. 1992 Mar;12(3):1078-86. doi: 10.1128/mcb.12.3.1078-1086.1992. Mol Cell Biol. 1992. PMID: 1545790 Free PMC article.
In the yeast Saccharomyces cerevisiae, sporulation occurs in response to nutritional and genetic signals. ...IME4 is located between ADE5 and LYS5 on chromosome VII....
In the yeast Saccharomyces cerevisiae, sporulation occurs in response to nutritional and genetic signals. ...IME4 …
Yeast targets for mRNA methylation.
Bodi Z, Button JD, Grierson D, Fray RG. Bodi Z, et al. Nucleic Acids Res. 2010 Sep;38(16):5327-35. doi: 10.1093/nar/gkq266. Epub 2010 Apr 26. Nucleic Acids Res. 2010. PMID: 20421205 Free PMC article.
N(6)-Methyladenosine (m(6)A) is a modified base present in the mRNA of all higher eukaryotes and in Saccharomyces cerevisiae, where there is an increase in m(6)A levels during sporulation. The methyltransferase, Ime4, is responsible for this modification and …
N(6)-Methyladenosine (m(6)A) is a modified base present in the mRNA of all higher eukaryotes and in Saccharomyces cerevisiae, …
Sporulation in Ashbya gossypii.
Wendland J. Wendland J. J Fungi (Basel). 2020 Aug 29;6(3):157. doi: 10.3390/jof6030157. J Fungi (Basel). 2020. PMID: 32872517 Free PMC article. Review.
Ashbya gossypii is a filamentous ascomycete belonging to the yeast family of Saccharomycetaceae. At the end of its growth phase Ashbya generates abundant amounts of riboflavin and spores that form within sporangia derived from fragmented cellular compartments of hyphae. .. …
Ashbya gossypii is a filamentous ascomycete belonging to the yeast family of Saccharomycetaceae. At the end of its growth phase Ashby …
Manipulation of IME4 expression, a global regulation strategy for metabolic engineering in Saccharomyces cerevisiae.
Zhu J, An T, Zha W, Gao K, Li T, Zi J. Zhu J, et al. Acta Pharm Sin B. 2023 Jun;13(6):2795-2806. doi: 10.1016/j.apsb.2023.01.002. Epub 2023 Jan 10. Acta Pharm Sin B. 2023. PMID: 37425036 Free PMC article.
Herein, we identify 1470 putatively m(6)A peaks within 1151 genes from the haploid Saccharomyces cerevisiae strain. Among them, the transcript levels of 94 genes falling into the pathways which are frequently optimized for chemical production, are remarkably altered …
Herein, we identify 1470 putatively m(6)A peaks within 1151 genes from the haploid Saccharomyces cerevisiae strain. Among them …
Regulated antisense transcription controls expression of cell-type-specific genes in yeast.
Gelfand B, Mead J, Bruning A, Apostolopoulos N, Tadigotla V, Nagaraj V, Sengupta AM, Vershon AK. Gelfand B, et al. Mol Cell Biol. 2011 Apr;31(8):1701-9. doi: 10.1128/MCB.01071-10. Epub 2011 Feb 7. Mol Cell Biol. 2011. PMID: 21300780 Free PMC article.
Transcriptome profiling studies have recently uncovered a large number of noncoding RNA transcripts (ncRNAs) in eukaryotic organisms, and there is growing interest in their role in the cell. For example, in haploid Saccharomyces cerevisiae cells, the expression of a …
Transcriptome profiling studies have recently uncovered a large number of noncoding RNA transcripts (ncRNAs) in eukaryotic organisms, and th …
Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesis.
Hongay CF, Orr-Weaver TL. Hongay CF, et al. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14855-60. doi: 10.1073/pnas.1111577108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873203 Free PMC article.
N(6)-methyladenosine is a nonediting RNA modification found in mRNA of all eukaryotes, from yeast to humans. Although the functional significance of N(6)-methyladenosine is unknown, the Inducer of MEiosis 4 (IME4) gene of Saccharomyces cerevisiae, whic …
N(6)-methyladenosine is a nonediting RNA modification found in mRNA of all eukaryotes, from yeast to humans. Although the functional …
Budding yeast as an ideal model for elucidating the role of N(6)-methyladenosine in regulating gene expression.
Albihlal WS, Chan WY, van Werven FJ. Albihlal WS, et al. Yeast. 2024 Apr;41(4):148-157. doi: 10.1002/yea.3925. Epub 2024 Jan 18. Yeast. 2024. PMID: 38238962 Review.
We propose that yeast serves as an exceptional model organism for the study of fundamental molecular mechanisms related to the function and regulation of m6A-modified mRNAs. The insights gained from yeast research not only expand our knowledge of mRNA modifications …
We propose that yeast serves as an exceptional model organism for the study of fundamental molecular mechanisms related to the functi …
29 results