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11,779 results

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Page 1
Nucleic acid-based electrochemical biosensors.
Gunasekaran BM, Srinivasan S, Ezhilan M, Nesakumar N. Gunasekaran BM, et al. Clin Chim Acta. 2024 Jun 1;559:119715. doi: 10.1016/j.cca.2024.119715. Epub 2024 May 10. Clin Chim Acta. 2024. PMID: 38735514 Review.
Finally, challenges associated with the fabrication of nucleic acid-based biosensors to achieve high sensitivity, selectivity, a wide detection range, and a low detection limit have been addressed. We believe that this review will provide valuable information for sc …
Finally, challenges associated with the fabrication of nucleic acid-based biosensors to achieve high sensitivity, selectivity, …
Surface Immobilized Nucleic Acid-Transcription Factor Quantum Dots for Biosensing.
Chen M, Nguyen TT, Varongchayakul N, Grazon C, Chern M, Baer RC, Lecommandoux S, Klapperich CM, Galagan JE, Dennis AM, Grinstaff MW. Chen M, et al. Adv Healthc Mater. 2020 Sep;9(17):e2000403. doi: 10.1002/adhm.202000403. Epub 2020 Jul 21. Adv Healthc Mater. 2020. PMID: 32691962 Free article.
Immobilization of biosensors on surfaces is a key step toward development of devices for real-world applications. Here the preparation, characterization, and evaluation of a surface-bound transcription factor-nucleic acid complex for analyte detection as an a …
Immobilization of biosensors on surfaces is a key step toward development of devices for real-world applications. Here the preparatio …
Multi-level patterning nucleic acid photolithography.
Hölz K, Schaudy E, Lietard J, Somoza MM. Hölz K, et al. Nat Commun. 2019 Aug 23;10(1):3805. doi: 10.1038/s41467-019-11670-3. Nat Commun. 2019. PMID: 31444344 Free PMC article.
The versatile and tunable self-assembly properties of nucleic acids and engineered nucleic acid constructs make them invaluable in constructing microscale and nanoscale devices, structures and circuits. ...The resulting high-complexity, micrometer-reso …
The versatile and tunable self-assembly properties of nucleic acids and engineered nucleic acid constructs make …
Nucleic acid based sensors.
Bier FF, Fürste JP. Bier FF, et al. EXS. 1997;80:97-120. doi: 10.1007/978-3-0348-9043-4_7. EXS. 1997. PMID: 9002209
Nucleic acids may be analyte or molecular recognition elements in biosensors. Both aspects merge in the genosensor approach, where detection of special sequences is facilitated by hybridization of a target nucleic acid to a complementary immobilized …
Nucleic acids may be analyte or molecular recognition elements in biosensors. Both aspects merge in the genosensor approach, w …
Nucleic Acid-based Enzyme Cascades-Current Trends and Future Perspectives.
Kröll S, Niemeyer CM. Kröll S, et al. Angew Chem Int Ed Engl. 2024 Jan 25;63(5):e202314452. doi: 10.1002/anie.202314452. Epub 2023 Nov 20. Angew Chem Int Ed Engl. 2024. PMID: 37870888 Review.
We emphasize the impact of the underlying design principles like DNA origami, efficient strategies for enzyme immobilization, as well as the importance of experimental design parameters and theoretical modeling. ...
We emphasize the impact of the underlying design principles like DNA origami, efficient strategies for enzyme immobilization, as well …
Application of peptide nucleic acid in electrochemical nucleic acid biosensors.
Sun H, Kong J, Zhang X. Sun H, et al. Biopolymers. 2021 Dec;112(12):e23464. doi: 10.1002/bip.23464. Epub 2021 Jul 2. Biopolymers. 2021. PMID: 34214202 Review.
In this review, we focus on improving the sensitivity and practicability of electrochemical DNA biosensing analysis methods and summarize a series of research work carried out by using electrically neutral peptide nucleic acid as an immobilized capture probe. …
In this review, we focus on improving the sensitivity and practicability of electrochemical DNA biosensing analysis methods and summarize a …
Nucleic acid separations utilizing immobilized metal affinity chromatography.
Murphy JC, Jewell DL, White KI, Fox GE, Willson RC. Murphy JC, et al. Biotechnol Prog. 2003 May-Jun;19(3):982-6. doi: 10.1021/bp025563o. Biotechnol Prog. 2003. PMID: 12790665
Immobilized metal affinity chromatography (IMAC) is widely used for protein purification, e.g., in the isolation of proteins bearing the well-known hexahistidine affinity tag. We report that IMAC matrixes can also adsorb single-stranded nucleic acids through …
Immobilized metal affinity chromatography (IMAC) is widely used for protein purification, e.g., in the isolation of proteins bearing …
Nucleic acid-based electrochemical biosensor: Recent advances in probe immobilization and signal amplification strategies.
Thapa K, Liu W, Wang R. Thapa K, et al. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022 Jan;14(1):e1765. doi: 10.1002/wnan.1765. Epub 2021 Nov 3. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022. PMID: 34734485 Review.
Here, we summarize the recent advances in DNA probe immobilization and signal amplification strategies with a special focus on DNA nanostructure-supported DNA probe immobilization method, which provides the opportunity to rationally control the distance between prob …
Here, we summarize the recent advances in DNA probe immobilization and signal amplification strategies with a special focus on DNA na …
Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis.
Lee J, Jackman JG, Kwun J, Manook M, Moreno A, Elster EA, Kirk AD, Leong KW, Sullenger BA. Lee J, et al. Biomaterials. 2017 Mar;120:94-102. doi: 10.1016/j.biomaterials.2016.12.024. Epub 2016 Dec 23. Biomaterials. 2017. PMID: 28049065 Free PMC article.
No effective therapeutic agents for the removal of DAMPs from blood or tissue fluid have been developed. Herein, we demonstrated that nucleic acid binding polymers, e.g., polyethylenimine (PEI) and polyamidoamine dendrimers, immobilized onto electrospun micro …
No effective therapeutic agents for the removal of DAMPs from blood or tissue fluid have been developed. Herein, we demonstrated that nuc …
Surface immobilization strategies for the development of electrochemical nucleic acid sensors.
Meng X, O'Hare D, Ladame S. Meng X, et al. Biosens Bioelectron. 2023 Oct 1;237:115440. doi: 10.1016/j.bios.2023.115440. Epub 2023 Jun 16. Biosens Bioelectron. 2023. PMID: 37406480 Review.
Following the recent pandemic and with the emergence of cell-free nucleic acids in liquid biopsies as promising biomarkers for a broad range of pathologies, there is an increasing demand for a new generation of nucleic acid tests, with a particular foc …
Following the recent pandemic and with the emergence of cell-free nucleic acids in liquid biopsies as promising biomarkers for …
11,779 results
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