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Year Number of Results
2014 2
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Page 1
A novel co-culture assay to assess anti-tumor CD8+ T cell cytotoxicity via luminescence and multicolor flow cytometry.
Olivo Pimentel V, Yaromina A, Marcus D, Dubois LJ, Lambin P. Olivo Pimentel V, et al. J Immunol Methods. 2020 Dec;487:112899. doi: 10.1016/j.jim.2020.112899. Epub 2020 Oct 15. J Immunol Methods. 2020. PMID: 33068606 Free article.
T cell immunotherapies have shown great promise in patients with advanced cancer disease, revolutionizing treatment. ...Our co-culture assay is therefore suitable as proof of principle for in vivo therapeutic studies testing immunotherapies, and specifically to asse …
T cell immunotherapies have shown great promise in patients with advanced cancer disease, revolutionizing treatment. ...Our co-cultur …
Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7(th) immunorad conference.
Laurent PA, André F, Bobard A, Deandreis D, Demaria S, Depil S, Eichmüller SB, Fernandez-Palomo C, Foijer F, Galluzzi L, Galon J, Guckenberger M, Harrington KJ, Herrera FG, Huber PE, Italiano A, Karam SD, Kroemer G, Lambin P, Leuschner C, Mantovani A, Meylan E, Mondini M, Pittet MJ, Pouget JP, Remon J, Sørensen CS, Sotiriou C, Vanpouille-Box C, Weichselbaum RR, Welsh JW, Zitvogel L, Formenti SC, Deutsch E. Laurent PA, et al. Oncoimmunology. 2025 Dec;14(1):2432726. doi: 10.1080/2162402X.2024.2432726. Epub 2024 Dec 18. Oncoimmunology. 2025. PMID: 39696783 Free PMC article.
Over the last decade, the annual Immunorad Conference, held under the joint auspicies of Gustave Roussy (Villejuif, France) and the Weill Cornell Medical College (New-York, USA) has aimed at exploring the latest advancements in the fields of tumor immunology and radiotherapy-i …
Over the last decade, the annual Immunorad Conference, held under the joint auspicies of Gustave Roussy (Villejuif, France) and the Weill Co …
Charged Particle and Conventional Radiotherapy: Current Implications as Partner for Immunotherapy.
Marcus D, Lieverse RIY, Klein C, Abdollahi A, Lambin P, Dubois LJ, Yaromina A. Marcus D, et al. Cancers (Basel). 2021 Mar 23;13(6):1468. doi: 10.3390/cancers13061468. Cancers (Basel). 2021. PMID: 33806808 Free PMC article. Review.
Radiotherapy (RT) has been shown to interfere with inflammatory signals and to enhance tumor immunogenicity via, e.g., immunogenic cell death, thereby potentially augmenting the therapeutic efficacy of immunotherapy. Conventional RT consists predominantly of high energy ph …
Radiotherapy (RT) has been shown to interfere with inflammatory signals and to enhance tumor immunogenicity via, e.g., immunogenic cell deat …
Combining radiotherapy with immunotherapy: the past, the present and the future.
Van Limbergen EJ, De Ruysscher DK, Olivo Pimentel V, Marcus D, Berbee M, Hoeben A, Rekers N, Theys J, Yaromina A, Dubois LJ, Lambin P. Van Limbergen EJ, et al. Br J Radiol. 2017 Aug;90(1076):20170157. doi: 10.1259/bjr.20170157. Epub 2017 May 25. Br J Radiol. 2017. PMID: 28541096 Free PMC article. Review.
The advent of immunotherapy is currently revolutionizing the field of oncology, where different drugs are used to stimulate different steps in a failing cancer immune response chain. This review gives a basic overview of the immune response against cancer, as well as the h …
The advent of immunotherapy is currently revolutionizing the field of oncology, where different drugs are used to stimulate different …
Lymphocyte-Sparing Radiotherapy: The Rationale for Protecting Lymphocyte-rich Organs When Combining Radiotherapy With Immunotherapy.
Lambin P, Lieverse RIY, Eckert F, Marcus D, Oberije C, van der Wiel AMA, Guha C, Dubois LJ, Deasy JO. Lambin P, et al. Semin Radiat Oncol. 2020 Apr;30(2):187-193. doi: 10.1016/j.semradonc.2019.12.003. Semin Radiat Oncol. 2020. PMID: 32381298 Free PMC article. Review.
There is now strong clinical and preclinical evidence that lymphocytes, for example, CD8(+) T cells, are key effectors of immunotherapy and that irradiation of large blood vessels, the heart, and lymphoid organs (including nodes, spleen, bones containing bone marrow, and t …
There is now strong clinical and preclinical evidence that lymphocytes, for example, CD8(+) T cells, are key effectors of immunotherapy …
Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress.
Mowday AM, Guise CP, Ackerley DF, Minton NP, Lambin P, Dubois LJ, Theys J, Smaill JB, Patterson AV. Mowday AM, et al. Cancers (Basel). 2016 Jun 28;8(7):63. doi: 10.3390/cancers8070063. Cancers (Basel). 2016. PMID: 27367731 Free PMC article. Review.
The ability to target the immunosuppressive hypoxic tumour microenvironment using CDEPT may offer potential for synergy with recently developed immunotherapy strategies. Ultimately, clostridia may be most efficacious when combined with conventional therapies, such as radio …
The ability to target the immunosuppressive hypoxic tumour microenvironment using CDEPT may offer potential for synergy with recently develo …
Stereotactic ablative body radiotherapy combined with immunotherapy: present status and future perspectives.
Rekers NH, Troost EG, Zegers CM, Germeraad WT, Dubois LJ, Lambin P. Rekers NH, et al. Cancer Radiother. 2014 Oct;18(5-6):391-5. doi: 10.1016/j.canrad.2014.06.012. Epub 2014 Aug 30. Cancer Radiother. 2014. PMID: 25179250 Review.
This review explores the possibility of bimodal treatment combining radiotherapy with immunotherapy....
This review explores the possibility of bimodal treatment combining radiotherapy with immunotherapy....
How Advances in Imaging Will Affect Precision Radiation Oncology.
Jaffray DA, Das S, Jacobs PM, Jeraj R, Lambin P. Jaffray DA, et al. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):292-298. doi: 10.1016/j.ijrobp.2018.01.047. Epub 2018 Jan 31. Int J Radiat Oncol Biol Phys. 2018. PMID: 29726358
Thus, more precise intervention will enable fractionation schedules that better interoperate with advances such as immunotherapy. In the data set-rich era that promises precision and personalized medicine, the radiation oncology field will integrate these new data into hig …
Thus, more precise intervention will enable fractionation schedules that better interoperate with advances such as immunotherapy. In …
20 results