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Implementation of a sensitive troponin I assay and risk of recurrent myocardial infarction and death in patients with suspected acute coronary syndrome.
Mills NL, Churchhouse AM, Lee KK, Anand A, Gamble D, Shah AS, Paterson E, MacLeod M, Graham C, Walker S, Denvir MA, Fox KA, Newby DE. Mills NL, et al. JAMA. 2011 Mar 23;305(12):1210-6. doi: 10.1001/jama.2011.338. JAMA. 2011. PMID: 21427373
CONTEXT: Although troponin assays have become increasingly more sensitive, it is unclear whether further reductions in the threshold of detection for plasma troponin concentrations will improve clinical outcomes in patients with suspected acute coronar …
CONTEXT: Although troponin assays have become increasingly more sensitive, it is unclear whether further reductions in …
Association of a Novel Protocol for Rapid Exclusion of Myocardial Infarction With Resource Use in a US Safety Net Hospital.
Vigen R, Diercks DB, Hashim IA, Pandey A, Zhong L, Kutscher P, Fernandez F, Yu A, Bertulfo B, Molberg K, Metzger JC, Soto J, Alzubaidy D, Thibodeaux L, Joglar JA, Das SR, de Lemos JA. Vigen R, et al. JAMA Netw Open. 2020 Apr 1;3(4):e203359. doi: 10.1001/jamanetworkopen.2020.3359. JAMA Netw Open. 2020. PMID: 32320036 Free PMC article.
IMPORTANCE: High-sensitivity cardiac troponin T (hs-cTnT) protocols for the evaluation of chest pain in the emergency department (ED) may reduce unnecessary resource use and overcrowding. OBJECTIVE: To determine whether the implementation of a novel hs-cTnT p …
IMPORTANCE: High-sensitivity cardiac troponin T (hs-cTnT) protocols for the evaluation of chest pain in the emergency departme …
Evaluation of High-Sensitivity Cardiac Troponin I Levels in Patients With Suspected Acute Coronary Syndrome.
Carlton E, Greenslade J, Cullen L, Body R, Than M, Pickering JW, Aldous S, Carley S, Hammett C, Kendall J, Keevil B, Lord S, Parsonage W, Greaves K. Carlton E, et al. JAMA Cardiol. 2016 Jul 1;1(4):405-12. doi: 10.1001/jamacardio.2016.1309. JAMA Cardiol. 2016. PMID: 27438316
A total of 3155 patients presenting with symptoms suggestive of cardiac ischemia were included in the analysis. Eligible patients had a nonischemic electrocardiogram determined and high-sensitivity troponin I measured at presentation. The lower limit of detec …
A total of 3155 patients presenting with symptoms suggestive of cardiac ischemia were included in the analysis. Eligible patients had …
Assessment of Oxygen Supply-Demand Imbalance and Outcomes Among Patients With Type 2 Myocardial Infarction: A Secondary Analysis of the High-STEACS Cluster Randomized Clinical Trial.
Bularga A, Taggart C, Mendusic F, Kimenai DM, Wereski R, Lowry MTH, Lee KK, Ferry AV, Stewart SS, McAllister DA, Shah ASV, Anand A, Newby DE, Mills NL, Chapman AR; High-Sensitivity Troponin in the Evaluation of Patients with Suspected Acute Coronary Syndrome (High-STEACS) Investigators. Bularga A, et al. JAMA Netw Open. 2022 Jul 1;5(7):e2220162. doi: 10.1001/jamanetworkopen.2022.20162. JAMA Netw Open. 2022. PMID: 35816305 Free PMC article. Clinical Trial.
The diagnosis of myocardial infarction was adjudicated according to the Fourth Universal Definition of Myocardial Infarction and the primary factor associated with oxygen supply-demand imbalance in type 2 myocardial infarction was defined. This secondary analysis was not p …
The diagnosis of myocardial infarction was adjudicated according to the Fourth Universal Definition of Myocardial Infarction and the primary …