Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1996 1
1999 1
2005 3
2006 4
2007 3
2008 7
2009 6
2010 4
2011 6
2012 2
2013 5
2014 7
2015 4
2016 5
2017 4
2018 5
2019 3
2020 9
2021 10
2022 8
2023 10
2024 9
2025 8

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

113 results

Results by year

Filters applied: . Clear all
Page 1
Therapeutic properties of Inonotus obliquus (Chaga mushroom): A review.
Ern PTY, Quan TY, Yee FS, Yin ACY. Ern PTY, et al. Mycology. 2023 Oct 20;15(2):144-161. doi: 10.1080/21501203.2023.2260408. eCollection 2024. Mycology. 2023. PMID: 38813471 Free PMC article. Review.
Inonotus obliquus, also known as Chaga, is a medicinal mushroom that has been used for therapeutic purposes since the sixteenth century. ...Thus, this review aims to explore available information on the therapeutic potentials of Inonotus obliquus for t …
Inonotus obliquus, also known as Chaga, is a medicinal mushroom that has been used for therapeutic purposes since the sixteent …
Anti-cancer activity of Chaga mushroom (Inonotus obliquus) against dog bladder cancer organoids.
Abugomaa A, Elbadawy M, Ishihara Y, Yamamoto H, Kaneda M, Yamawaki H, Shinohara Y, Usui T, Sasaki K. Abugomaa A, et al. Front Pharmacol. 2023 Apr 19;14:1159516. doi: 10.3389/fphar.2023.1159516. eCollection 2023. Front Pharmacol. 2023. PMID: 37153767 Free PMC article.
Despite its disadvantages, chemotherapy is still commonly used for the treatment of bladder cancer (BC). Developing natural supplements that can target cancer stem cells (CSCs) which cause drug resistance and distant metastasis is necessary. ...Interestingly, the co …
Despite its disadvantages, chemotherapy is still commonly used for the treatment of bladder cancer (BC). Developing natural supplemen …
Inonotus obliquus - from folk medicine to clinical use.
Szychowski KA, Skóra B, Pomianek T, Gmiński J. Szychowski KA, et al. J Tradit Complement Med. 2020 Aug 22;11(4):293-302. doi: 10.1016/j.jtcme.2020.08.003. eCollection 2021 Jul. J Tradit Complement Med. 2020. PMID: 34195023 Free PMC article. Review.
The Inonotus obliquus (I. obliquus) mushroom was traditionally used to treat various gastrointestinal diseases. ...This review summarizes the therapeutic potential of I. obliquus extracts in counteracting the progression of cancers and diabetes mellitus as we …
The Inonotus obliquus (I. obliquus) mushroom was traditionally used to treat various gastrointestinal diseases. ...This review …
Inonotus obliquus polysaccharides induces apoptosis of lung cancer cells and alters energy metabolism via the LKB1/AMPK axis.
Jiang S, Shi F, Lin H, Ying Y, Luo L, Huang D, Luo Z. Jiang S, et al. Int J Biol Macromol. 2020 May 15;151:1277-1286. doi: 10.1016/j.ijbiomac.2019.10.174. Epub 2019 Nov 18. Int J Biol Macromol. 2020. PMID: 31751687
The present study explores the mechanisms underlying the anti-cancer action of Inonotus obliquus polysaccharides (IOP). Thus, we characterized the IOP components extracted from Chaga sclerotium and, found that the extracts contained 70% polysaccharides with a …
The present study explores the mechanisms underlying the anti-cancer action of Inonotus obliquus polysaccharides (IOP). …
Inonotsutriol E from Inonotus obliquus exhibits promising anti breast cancer activity via regulating the JAK2/STAT3 signaling pathway.
Shan P, Wang C, Chen H, Yu J, Zhang H. Shan P, et al. Bioorg Chem. 2023 Oct;139:106741. doi: 10.1016/j.bioorg.2023.106741. Epub 2023 Jul 17. Bioorg Chem. 2023. PMID: 37480812
The aim of the present study was to investigate the small molecule anticancer agents in the medicinal fungus Inonotus obliquus and further characterize their possible molecular mechanisms. Chemical fractionation of the ethanol extract of this fungus yielded a panel …
The aim of the present study was to investigate the small molecule anticancer agents in the medicinal fungus Inonotus obliquus …
Chaga mushroom: a super-fungus with countless facets and untapped potential.
Fordjour E, Manful CF, Javed R, Galagedara LW, Cuss CW, Cheema M, Thomas R. Fordjour E, et al. Front Pharmacol. 2023 Dec 5;14:1273786. doi: 10.3389/fphar.2023.1273786. eCollection 2023. Front Pharmacol. 2023. PMID: 38116085 Free PMC article. Review.
Inonotus obliquus (Chaga mushroom) is an inexpensive fungus with a broad range of traditional and medicinal applications. These applications include therapy for breast, cervix, and skin cancers, as well as treating diabetes. However, its benefits are virtuall …
Inonotus obliquus (Chaga mushroom) is an inexpensive fungus with a broad range of traditional and medicinal applications. Thes …
Biological Synthesis of Bioactive Gold Nanoparticles from Inonotus obliquus for Dual Chemo-Photothermal Effects against Human Brain Cancer Cells.
Shukurov I, Mohamed MS, Mizuki T, Palaninathan V, Ukai T, Hanajiri T, Maekawa T. Shukurov I, et al. Int J Mol Sci. 2022 Feb 18;23(4):2292. doi: 10.3390/ijms23042292. Int J Mol Sci. 2022. PMID: 35216406 Free PMC article.
The possibility for an ecologically friendly and simple production of gold nanoparticles (AuNPs) with Chaga mushroom (Inonotus obliquus) (Ch-AuNPs) is presented in this study. Chaga extract's reducing potential was evaluated at varied concentrations and temperatures …
The possibility for an ecologically friendly and simple production of gold nanoparticles (AuNPs) with Chaga mushroom (Inonotus obl …
Composition of Triterpenoids in Inonotus obliquus and Their Anti-Proliferative Activity on Cancer Cell Lines.
Kim J, Yang SC, Hwang AY, Cho H, Hwang KT. Kim J, et al. Molecules. 2020 Sep 6;25(18):4066. doi: 10.3390/molecules25184066. Molecules. 2020. PMID: 32899899 Free PMC article.
The objective of this study was to determine the composition of triterpenoids in the extracts from the inner and outer parts of Inonotus obliquus and to evaluate their anti-proliferative activity against cancer cell lines (HT-29, AGS, MCF-7, and PC3). ...Anti …
The objective of this study was to determine the composition of triterpenoids in the extracts from the inner and outer parts of Inonotus …
Inonotus obliquus Polysaccharide Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Cancer in Mice via Activation of the NLRP3 Inflammasome.
Li J, Qu C, Li F, Chen Y, Zheng J, Xiao Y, Jin Q, Jin G, Huang X, Jin D. Li J, et al. Front Pharmacol. 2021 Feb 2;11:621835. doi: 10.3389/fphar.2020.621835. eCollection 2020. Front Pharmacol. 2021. PMID: 33603669 Free PMC article.
Inonotus obliquus polysaccharide (IOP), the primary constituent of the parasitic fungus Inonotus obliquus, has anti-tumor, anti-inflammatory, anti-oxidation effects. However, the roles of IOP on colitis-associated cancer (CAC) are still unclear. …
Inonotus obliquus polysaccharide (IOP), the primary constituent of the parasitic fungus Inonotus obliquus, has a …
Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity.
Wold CW, Christopoulos PF, Arias MA, Dzovor DE, Øynebråten I, Corthay A, Inngjerdingen KT. Wold CW, et al. Commun Biol. 2024 Feb 23;7(1):222. doi: 10.1038/s42003-024-05853-y. Commun Biol. 2024. PMID: 38396285 Free PMC article.
Here, we evaluate six polysaccharides isolated from the medicinal fungus Inonotus obliquus for their ability to activate mouse and human macrophages. We identify two water-soluble polysaccharides, AcF1 and AcF3, being able to trigger several critical antitumor funct …
Here, we evaluate six polysaccharides isolated from the medicinal fungus Inonotus obliquus for their ability to activate mouse …
113 results