Inositol hexaphosphate inhibits constitutive activation of NF- kappa B in androgen-independent human prostate carcinoma DU145 cells.
Anticancer Res. 2003.
PMID: 14666688
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inositol hexaphosphate and nf kappab
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Inositol hexaphosphate inhibits constitutive activation of NF- kappa B in androgen-independent human prostate carcinoma DU145 cells.
Anticancer Res. 2003 Sep-Oct;23(5A):3855-61.
Anticancer Res. 2003.
PMID: 14666688
RESULTS: Treatment of cells with 1 and 2 mM doses of IP6 resulted in a strong inhibition of NF-kappa B activation, which was consistent with a decrease in nuclear levels of NF-kappa B sub-unit proteins p65 and p50. IP6-treated cells also …
RESULTS: Treatment of cells with 1 and 2 mM doses of IP6 resulted in a strong inhibition of NF-kappa B activation, whic …
Inositol hexaphosphate and paclitaxel: symbiotic treatment of oral cavity squamous cell carcinoma.
Laryngoscope. 2007 Aug;117(8):1381-8. doi: 10.1097/MLG.0b013e3180679e59.
Laryngoscope. 2007.
PMID: 17607147
The activation of this gene can be correlated with apoptosis resistance. Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate. ...Paclitaxel treatments caused increased NF-kappaB activation in the same cell lines. IP6 was obse …
The activation of this gene can be correlated with apoptosis resistance. Inositol hexaphosphate (IP6) is a naturally occurring …
Inositol hexaphosphate inhibits ultraviolet B-induced signal transduction.
Mol Carcinog. 2001 Jul;31(3):139-44. doi: 10.1002/mc.1048.
Mol Carcinog. 2001.
PMID: 11479922
Inositol hexaphosphate (InsP6) has an effective anticancer action in many experimental models in vivo and in vitro. ...Because AP-1 and NF-kappaB are important nuclear transcription factors that are related to tumor promotion, our work suggests that InsP6 pre …
Inositol hexaphosphate (InsP6) has an effective anticancer action in many experimental models in vivo and in vitro. ...Because …
Involvement of STAT3, NF-kappaB and associated downstream molecules before and after the onset of urethane induced lung tumors in mouse.
Environ Toxicol Pharmacol. 2012 Sep;34(2):502-511. doi: 10.1016/j.etap.2012.06.007. Epub 2012 Jul 1.
Environ Toxicol Pharmacol. 2012.
PMID: 22797328
Here we have shown the alteration of transcription factors STAT3, NF-kappaB and downstream associated molecules much before the appearance of lung tumor and their response to antitumor agent, inositol hexaphosphate. ...We suggest that the alterations of STAT3 …
Here we have shown the alteration of transcription factors STAT3, NF-kappaB and downstream associated molecules much before the appea …
Phytic acid attenuates inflammatory responses and the levels of NF-kappaB and p-ERK in MPTP-induced Parkinson's disease model of mice.
Neurosci Lett. 2015 Jun 15;597:132-6. doi: 10.1016/j.neulet.2015.04.040. Epub 2015 Apr 27.
Neurosci Lett. 2015.
PMID: 25929185
Phytic acid (PA) is a naturally occurring constituent which exhibits protective action in Parkinson's disease (PD). ...Via western blot assay, expressions of nuclear factor kappaB (NF-kappaB) and phosphorylated extracellular signal-regulated kinase (p-ERK) we …
Phytic acid (PA) is a naturally occurring constituent which exhibits protective action in Parkinson's disease (PD). ...Via wes …
Effect of inositol hexaphosphate on the development of UVB-induced skin tumors in SKH1 hairless mice.
Comp Med. 2009 Apr;59(2):147-52.
Comp Med. 2009.
PMID: 19389306
Free PMC article.
Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate that is abundant in many plants and in various high-fiber foods, such as cereals and legumes. ...
Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate that is abundant in many plants and in v …
Effects of food factors on signal transduction pathways.
Biofactors. 2000;12(1-4):17-28. doi: 10.1002/biof.5520120104.
Biofactors. 2000.
PMID: 11216482
Review.
At the same dose range that inhibited cell transformation, EGCG and theaflavins inhibited activator protein-1 (AP-1) activation. These compounds also inhibited ultraviolet B (UVB)-induced AP-1 and nuclear factor kappa B (NFkappaB)-dependent transcriptional ac …
At the same dose range that inhibited cell transformation, EGCG and theaflavins inhibited activator protein-1 (AP-1) activation. These compo …
Signal transduction pathways: targets for chemoprevention of skin cancer.
Lancet Oncol. 2000 Nov;1:181-8. doi: 10.1016/s1470-2045(00)00029-2.
Lancet Oncol. 2000.
PMID: 11905657
Review.
The effect of phytic acid on the expression of NF-kappaB, IL-6 and IL-8 in IL-1beta-stimulated human colonic epithelial cells.
Acta Pol Pharm. 2012 Nov-Dec;69(6):1313-9.
Acta Pol Pharm. 2012.
PMID: 23285696
Free article.
The expression of both interleukins is regulated by nuclear factor KB (NF-kappaB). Phytic acid (IP6) is an essential component of high fiber diet. ...The aim of this study was to analyze the effect of IP6 on the expression of IL-6 and IL-8 as well as p50 and …
The expression of both interleukins is regulated by nuclear factor KB (NF-kappaB). Phytic acid (IP6) is an essential co …
Evaluation of the expression of transcriptional factor NF-kappaB induced by phytic acid in colon cancer cells.
Acta Pol Pharm. 2008 Nov-Dec;65(6):697-702.
Acta Pol Pharm. 2008.
PMID: 19172851
Free article.
Over the last years phytic acid, a hexaphosphorylated inositol (IP6) has attracted particular attention due to its anti-cancer activity, however, the molecular mechanisms of its action have not been elucidated, as yet. The aim of this study was to evaluate th …
Over the last years phytic acid, a hexaphosphorylated inositol (IP6) has attracted particular attention due to its anti …