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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 1
2000 1
2001 1
2005 2
2006 4
2007 1
2008 1
2009 1
2010 1
2014 1
2015 1
2020 0
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16 results
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Page 1
Prostate cancer and inositol hexaphosphate: efficacy and mechanisms.
Singh RP, Agarwal R. Singh RP, et al. Anticancer Res. 2005 Jul-Aug;25(4):2891-903. Anticancer Res. 2005. PMID: 16080543 Free article. Review.
Several mechanisms, including overexpression of growth, survival and angiogenic factors and their receptors, together with a loss/decrease of tumor suppressor p53, retinoblastoma and cyclin-dependent kinase inhibitor, have been implicated in PCA growth and progression. ... …
Several mechanisms, including overexpression of growth, survival and angiogenic factors and their receptors, together with a loss/decrease o …
Inositol hexaphosphate induces apoptosis by coordinative modulation of P53, Bcl-2 and sequential activation of caspases in 7,12 dimethylbenz[a]anthracene exposed mouse epidermis.
Singh J, Gupta KP. Singh J, et al. J Environ Pathol Toxicol Oncol. 2008;27(3):209-17. doi: 10.1615/jenvironpatholtoxicoloncol.v27.i3.50. J Environ Pathol Toxicol Oncol. 2008. PMID: 18652568
Inositol hexaphosphate (IP6) is a major constituent of most cereals, legumes, nuts, oil seeds, and soybean. Anticancer effects of IP6 have been demonstrated in different experimental models. ...Exogenously administered IP6 is rapidly taken into the cells and dephosp …
Inositol hexaphosphate (IP6) is a major constituent of most cereals, legumes, nuts, oil seeds, and soybean. Anticancer effects …
Quantitative analysis of the level of p53 and p21(WAF1) mRNA in human colon cancer HT-29 cells treated with inositol hexaphosphate.
Weglarz L, Molin I, Orchel A, Parfiniewicz B, Dzierzewicz Z. Weglarz L, et al. Acta Biochim Pol. 2006;53(2):349-56. Epub 2006 May 30. Acta Biochim Pol. 2006. PMID: 16733561 Free article.
The aim of this study was to analyze the molecular mechanism of inositol hexaphosphate (InsP(6)) action through which it may inhibit proliferation of colon cancer cells and cell cycle progression. ...InsP(6) stimulated p53 and p21(WAF1) expression at the mRNA …
The aim of this study was to analyze the molecular mechanism of inositol hexaphosphate (InsP(6)) action through which it may i …
p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.
Roy S, Gu M, Ramasamy K, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. Roy S, et al. Cancer Res. 2009 Feb 1;69(3):1166-73. doi: 10.1158/0008-5472.CAN-08-3115. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176374 Free PMC article.
Inositol hexaphosphate (IP6) causes G(1) arrest and increases cyclin-dependent kinase inhibitors p21/Cip1 and p27/Kip1 protein levels in human prostate cancer (PCa) DU145 cells lacking functional p53. ...Together, these results provide evidence, for the first …
Inositol hexaphosphate (IP6) causes G(1) arrest and increases cyclin-dependent kinase inhibitors p21/Cip1 and p27/Kip1 protein …
Effects of inositol hexaphosphate on proliferation of HT-29 human colon carcinoma cell line.
Tian Y, Song Y. Tian Y, et al. World J Gastroenterol. 2006 Jul 14;12(26):4137-42. doi: 10.3748/wjg.v12.i26.4137. World J Gastroenterol. 2006. PMID: 16830361 Free PMC article.
AIM: To investigate the effects of inositol hexaphosphate (IP(6)) on proliferation of HT-29 human colon carcinoma cell line. ...Analysis of cell cycle regulator expression revealed that IP(6) reduced the abnormal expression of P53 and PCNA and induced the exp …
AIM: To investigate the effects of inositol hexaphosphate (IP(6)) on proliferation of HT-29 human colon carcinoma cell line. . …
Metabolism and cellular functions of IP6: a review.
Shamsuddin AM. Shamsuddin AM. Anticancer Res. 1999 Sep-Oct;19(5A):3733-6. Anticancer Res. 1999. PMID: 10625949 Review.
Inositol hexaphosphate (IP6) has a demonstrably effective anti-cancer action against a variety of experimental tumors. However, the mechanisms of its actions are yet to be completely discerned. ...Studies of the expression of tumor suppressor gene demonstrate up-reg …
Inositol hexaphosphate (IP6) has a demonstrably effective anti-cancer action against a variety of experimental tumors. However …
Up-regulation of the tumor suppressor gene p53 and WAF1 gene expression by IP6 in HT-29 human colon carcinoma cell line.
Saied IT, Shamsuddin AM. Saied IT, et al. Anticancer Res. 1998 May-Jun;18(3A):1479-84. Anticancer Res. 1998. PMID: 9673359
Inositol hexaphosphate (InsP6 or IP6) ubiquitous in various cells has a novel anti-cancer action both in vivo and in vitro. IP6 inhibits cell growth, decreases cell proliferation and also causes differentiation of various cell lines, including HT-29 human colon carc …
Inositol hexaphosphate (InsP6 or IP6) ubiquitous in various cells has a novel anti-cancer action both in vivo and in vitro. IP …
Rice bran phytic acid induced apoptosis through regulation of Bcl-2/Bax and p53 genes in HepG2 human hepatocellular carcinoma cells.
Al-Fatlawi AA, Al-Fatlawi AA, Irshad M, Zafaryab M, Rizvi MM, Ahmad A. Al-Fatlawi AA, et al. Asian Pac J Cancer Prev. 2014;15(8):3731-6. doi: 10.7314/apjcp.2014.15.8.3731. Asian Pac J Cancer Prev. 2014. PMID: 24870784 Free article.
Phytic acid (PA) has been reported to have positive nutritional benefits and prevent cancer formation. This study investigated the anticancer activity of rice bran PA against hepatocellular carcinoma (HepG2) cells. ...PA treated HepG2 cells showed up-regulation of …
Phytic acid (PA) has been reported to have positive nutritional benefits and prevent cancer formation. This study investigated …
P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Panduri V, Surapureddi S, Soberanes S, Weitzman SA, Chandel N, Kamp DW. Panduri V, et al. Am J Respir Cell Mol Biol. 2006 Apr;34(4):443-52. doi: 10.1165/rcmb.2005-0352OC. Epub 2005 Dec 15. Am J Respir Cell Mol Biol. 2006. PMID: 16357363 Free PMC article.
Further, pifithrin, E6, phytic acid, or rho(0)-A549 cells (cells incapable of mitochondrial reactive oxygen species production) block asbestos-induced p53 activation. Finally, we show that asbestos augments p53 expression in cells at the bronchoalveola …
Further, pifithrin, E6, phytic acid, or rho(0)-A549 cells (cells incapable of mitochondrial reactive oxygen species production …
IMPACT OF GENISTEIN AND PHYTIC ACID ON THE VIABILITY AND PROLIFERATION ACTIVITY OF NASAL POLYPS' CELLS IN AN IN VITRO MODEL.
Frączek M, Kuśmierz D, Rostkowska-Nadolska B, Kręcicki T, Latocha MT. Frączek M, et al. Acta Pol Pharm. 2015 Jul-Aug;72(4):719-25. Acta Pol Pharm. 2015. PMID: 26647629 Free article.
Genistein and phytic acid significantly and in dose-specific manner decreased nasal polyps fibroblasts survivability and growth rate. ...Genistein and phytic acid have significant potential for a therapeutic role in the treatment of chronic rhinosinusi …
Genistein and phytic acid significantly and in dose-specific manner decreased nasal polyps fibroblasts survivability and growt …
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