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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 2
1966 4
1967 4
1968 1
1969 2
1970 4
1971 1
1972 4
1973 3
1974 5
1975 5
1976 1
1977 4
1978 5
1979 4
1980 2
1981 3
1982 1
1983 3
1984 2
1985 6
1986 5
1987 1
1988 3
1989 4
1990 3
1991 1
1992 7
1993 3
1994 10
1995 14
1996 15
1997 16
1998 13
1999 12
2000 13
2001 13
2002 14
2003 23
2004 23
2005 23
2006 39
2007 21
2008 23
2009 28
2010 29
2011 28
2012 46
2013 44
2014 38
2015 43
2016 44
2017 51
2018 43
2019 40
2020 42
2021 42
2022 30
2023 32
2024 39
2025 32
2026 3

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910 results

Results by year

Filters applied: Clinical Trial, Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines.
Fitz V, Graca S, Mahalingaiah S, Liu J, Lai L, Butt A, Armour M, Rao V, Naidoo D, Maunder A, Yang G, Vaddiparthi V, Witchel SF, Pena A, Spritzer PM, Li R, Tay C, Mousa A, Teede H, Ee C. Fitz V, et al. J Clin Endocrinol Metab. 2024 May 17;109(6):1630-1655. doi: 10.1210/clinem/dgad762. J Clin Endocrinol Metab. 2024. PMID: 38163998 Free PMC article.
DATA SYNTHESIS: Thirteen comparisons were assessed, with 3 in meta-analyses. Evidence suggests benefits for myo-inositol or D-chiro-inositol (DCI) for some metabolic measures and potential benefits from DCI for ovulation, but inositol may have no effect on ot …
DATA SYNTHESIS: Thirteen comparisons were assessed, with 3 in meta-analyses. Evidence suggests benefits for myo-inositol or D-chiro- …
Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyirády P, Ács N, Várbíró S, Horváth EM. Greff D, et al. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10. doi: 10.1186/s12958-023-01055-z. Reprod Biol Endocrinol. 2023. PMID: 36703143 Free PMC article.
RESULTS: Twenty-six RCTs were identified, including data of 1691 patients (806 inositol, 311 with placebo, and 509 metformin groups). In patients treated with inositols, the risk (CI: 1.13; 2.85) of having a regular menstrual cycle was found by 1.79 higher than in t …
RESULTS: Twenty-six RCTs were identified, including data of 1691 patients (806 inositol, 311 with placebo, and 509 metformin groups). …
Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis.
Zhao H, Xing C, Zhang J, He B. Zhao H, et al. Reprod Health. 2021 Aug 18;18(1):171. doi: 10.1186/s12978-021-01207-7. Reprod Health. 2021. PMID: 34407851 Free PMC article.
Myo-inositol combined with D-chiro-inositol is particularly efficacious in menstrual recovery. ...Myo-inositol combined with D-chiro-inositol is particularly efficacious in menstrual recovery. ...
Myo-inositol combined with D-chiro-inositol is particularly efficacious in menstrual recovery. ...Myo-inositol combined …
Myo-inositol vs. D-chiro inositol in PCOS treatment.
Formuso C, Stracquadanio M, Ciotta L. Formuso C, et al. Minerva Ginecol. 2015 Aug;67(4):321-5. Epub 2015 Feb 11. Minerva Ginecol. 2015. PMID: 25670222 Clinical Trial.
METHODS: The aim of our study was to compare the clinical, endocrine and metabolic response after 6 months of therapy in 137 PCOS women characterized by oligomenorrhea and/or acne and/or mild hirsutism and insulin-resistance. The patients were treated with myo-inositol or …
METHODS: The aim of our study was to compare the clinical, endocrine and metabolic response after 6 months of therapy in 137 PCOS women char …
Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes.
Motuhifonua SK, Lin L, Alsweiler J, Crawford TJ, Crowther CA. Motuhifonua SK, et al. Cochrane Database Syst Rev. 2023 Feb 15;2(2):CD011507. doi: 10.1002/14651858.CD011507.pub3. Cochrane Database Syst Rev. 2023. PMID: 36790138 Free PMC article. Review.
BACKGROUND: Gestational diabetes with onset or first recognition during pregnancy is an increasing problem worldwide. Myo-inositol, an isomer of inositol, is a naturally occurring sugar commonly found in cereals, corn, legumes and meat. Myo-inositol is one of …
BACKGROUND: Gestational diabetes with onset or first recognition during pregnancy is an increasing problem worldwide. Myo-inositol, a …
Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptives.
Pkhaladze L, Russo M, Unfer V, Nordio M, Basciani S, Khomasuridze A. Pkhaladze L, et al. Eur Rev Med Pharmacol Sci. 2021 Dec;25(23):7476-7485. doi: 10.26355/eurrev_202112_27447. Eur Rev Med Pharmacol Sci. 2021. Retraction in: Eur Rev Med Pharmacol Sci. 2026 Feb;30(2):51. doi: 10.26355/eurrev_202602_37681. PMID: 34919250 Free article. Retracted. Clinical Trial.
They were treated for 3 months either with oral contraceptive pills (OCP) drospirenone/ethinylestradiol (group A), myo-Inositol (myo-Ins) (group B), or OCP plus myo-Ins (group C). Data were analyzed with a descriptive statistics summarizing quantitative variables including …
They were treated for 3 months either with oral contraceptive pills (OCP) drospirenone/ethinylestradiol (group A), myo-Inositol (myo- …
Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study.
Kachhawa G, Senthil Kumar KV, Kulshrestha V, Khadgawat R, Mahey R, Bhatla N. Kachhawa G, et al. Int J Gynaecol Obstet. 2022 Aug;158(2):278-284. doi: 10.1002/ijgo.13971. Epub 2021 Nov 10. Int J Gynaecol Obstet. 2022. PMID: 34624138 Clinical Trial.
OBJECTIVE: To compare the effect of myo-inositol and d-chiro-inositol in combination (MI + DCI) with combined hormonal contraceptive (CHC) on menstrual cycle regulation in young Indian women with polycystic ovary syndrome (PCOS). ...TRIAL REGISTRATION: Clinical Tria …
OBJECTIVE: To compare the effect of myo-inositol and d-chiro-inositol in combination (MI + DCI) with combined hormonal contrac …
Inositol for subfertile women with polycystic ovary syndrome.
Showell MG, Mackenzie-Proctor R, Jordan V, Hodgson R, Farquhar C. Showell MG, et al. Cochrane Database Syst Rev. 2018 Dec 20;12(12):CD012378. doi: 10.1002/14651858.CD012378.pub2. Cochrane Database Syst Rev. 2018. PMID: 30570133 Free PMC article.
This review assessed the evidence for the effectiveness of inositol in subfertile women with a diagnosis of PCOS. OBJECTIVES: To evaluate the effectiveness and safety of oral supplementation of inositol for reproductive outcomes among subfertile women with PCOS who …
This review assessed the evidence for the effectiveness of inositol in subfertile women with a diagnosis of PCOS. OBJECTIVES: To eval …
Inositol Nutritional Supplementation for the Prevention of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Wei J, Yan J, Yang H. Wei J, et al. Nutrients. 2022 Jul 9;14(14):2831. doi: 10.3390/nu14142831. Nutrients. 2022. PMID: 35889788 Free PMC article.
This study was aimed at assessing the efficacy and safety of inositol nutritional supplementation during pregnancy for the prevention of GDM. PubMed, Embase, MEDLINE, and Cochrane library were systematically searched for randomized controlled trails (RCTs) in this field un …
This study was aimed at assessing the efficacy and safety of inositol nutritional supplementation during pregnancy for the prevention …
The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios.
Nordio M, Basciani S, Camajani E. Nordio M, et al. Eur Rev Med Pharmacol Sci. 2019 Jun;23(12):5512-5521. doi: 10.26355/eurrev_201906_18223. Eur Rev Med Pharmacol Sci. 2019. PMID: 31298405 Free article. Clinical Trial.
OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI), in the therapy of polycystic ovary syndrome (PCOS). PATIENTS AND METHODS: fifty …
OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, …
910 results