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278 results

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Page 1
Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines.
Fitz V, Graca S, Mahalingaiah S, Liu J, Lai L, Butt A, Armour M, Rao V, Naidoo D, Maunder A, Yang G, Vaddiparthi V, Witchel SF, Pena A, Spritzer PM, Li R, Tay C, Mousa A, Teede H, Ee C. Fitz V, et al. J Clin Endocrinol Metab. 2024 May 17;109(6):1630-1655. doi: 10.1210/clinem/dgad762. J Clin Endocrinol Metab. 2024. PMID: 38163998 Free PMC article.
CONTEXT: Insulin resistance is common in women with polycystic ovary syndrome (PCOS). Inositol may have insulin sensitizing effects; however, its efficacy in the management of PCOS remains indeterminate. OBJECTIVE: To inform the 2023 internation …
CONTEXT: Insulin resistance is common in women with polycystic ovary syndrome (PCOS). Inositol may have insulin …
Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS).
Fruzzetti F, Perini D, Russo M, Bucci F, Gadducci A. Fruzzetti F, et al. Gynecol Endocrinol. 2017 Jan;33(1):39-42. doi: 10.1080/09513590.2016.1236078. Epub 2016 Nov 3. Gynecol Endocrinol. 2017. PMID: 27808588 Clinical Trial.
Insulin resistance (IR) plays a pivotal role in PCOS. Insulin-sensitizer agents such as metformin and inositols have been shown to improve the endocrine and metabolic aspects of PCOS. ...No significant changes in acne and hirsutism were observed …
Insulin resistance (IR) plays a pivotal role in PCOS. Insulin-sensitizer agents such as metformin and inositols …
Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis.
Zhao H, Xing C, Zhang J, He B. Zhao H, et al. Reprod Health. 2021 Aug 18;18(1):171. doi: 10.1186/s12978-021-01207-7. Reprod Health. 2021. PMID: 34407851 Free PMC article.
CONCLUSIONS: Ours is the first study to report that for women with PCOS, myo-inositol combined with D-chiro-inositol and metformin combined with thiazolidinediones appear superior to metformin alone in improving insulin resistance and decreasing total …
CONCLUSIONS: Ours is the first study to report that for women with PCOS, myo-inositol combined with D-chiro-inositol an …
Inositol as putative integrative treatment for PCOS.
Genazzani AD. Genazzani AD. Reprod Biomed Online. 2016 Dec;33(6):770-780. doi: 10.1016/j.rbmo.2016.08.024. Epub 2016 Sep 16. Reprod Biomed Online. 2016. PMID: 27717596 Free article. Review.
As metformin often induces side effects, new integrative strategies have been proposed to treat insulin resistance, such as the use of inositols. Such compounds are mainly represented in humans by two inositol stereoisomers: myo-inositol (MYO) and d-ch …
As metformin often induces side effects, new integrative strategies have been proposed to treat insulin resistance, such as the use o …
Controversies in the Pathogenesis, Diagnosis and Treatment of PCOS: Focus on Insulin Resistance, Inflammation, and Hyperandrogenism.
Armanini D, Boscaro M, Bordin L, Sabbadin C. Armanini D, et al. Int J Mol Sci. 2022 Apr 8;23(8):4110. doi: 10.3390/ijms23084110. Int J Mol Sci. 2022. PMID: 35456928 Free PMC article. Review.
Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with symptoms that vary with the age of the patient, typically characterized by hyperandrogenism, chronic oligo-anovulation, and/or several metabolic disorders. ...In this review, we discuss s …
Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with symptoms that vary with the age of the patient, …
Myo-inositol vs. D-chiro inositol in PCOS treatment.
Formuso C, Stracquadanio M, Ciotta L. Formuso C, et al. Minerva Ginecol. 2015 Aug;67(4):321-5. Epub 2015 Feb 11. Minerva Ginecol. 2015. PMID: 25670222 Clinical Trial.
The patients were treated with myo-inositol or with D-chiro-inositol or with placebo. RESULTS: Our study showed that both myo-inositol (MI-PG) and D-chiro inositol (DCI-PG) treatments are able to significantly improve the regularity of the menstrual cy …
The patients were treated with myo-inositol or with D-chiro-inositol or with placebo. RESULTS: Our study showed that both myo- …
Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome.
Alesi S, Ee C, Moran LJ, Rao V, Mousa A. Alesi S, et al. Adv Nutr. 2022 Aug 1;13(4):1243-1266. doi: 10.1093/advances/nmab141. Adv Nutr. 2022. PMID: 34970669 Free PMC article. Review.
Women with PCOS tend to be nutrient deficient in many common vitamins and minerals, thought to be associated with the psychological (depression, anxiety, etc.) and physiological (insulin resistance, diabetes, infertility, etc.) sequelae of the condition. ...The evid …
Women with PCOS tend to be nutrient deficient in many common vitamins and minerals, thought to be associated with the psychological ( …
Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyirády P, Ács N, Várbíró S, Horváth EM. Greff D, et al. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10. doi: 10.1186/s12958-023-01055-z. Reprod Biol Endocrinol. 2023. PMID: 36703143 Free PMC article.
BACKGROUND: Metformin is the gold standard insulin sensitizer, which is widely used to treat insulin resistance in polycystic ovary syndrome (PCOS). ...CONCLUSION: Inositol is an effective and safe treatment in PCOS. Moreover, inositols s …
BACKGROUND: Metformin is the gold standard insulin sensitizer, which is widely used to treat insulin resistance in polycystic …
Lifestyle management in polycystic ovary syndrome - beyond diet and physical activity.
Cowan S, Lim S, Alycia C, Pirotta S, Thomson R, Gibson-Helm M, Blackmore R, Naderpoor N, Bennett C, Ee C, Rao V, Mousa A, Alesi S, Moran L. Cowan S, et al. BMC Endocr Disord. 2023 Jan 16;23(1):14. doi: 10.1186/s12902-022-01208-y. BMC Endocr Disord. 2023. PMID: 36647089 Free PMC article. Review.
There is limited evidence to recommend a specific diet composition for PCOS with approaches including modifying protein, carbohydrate or fat quality or quantity generally having similar effects on the presentations of PCOS. ...While optimising sleep and emotional we …
There is limited evidence to recommend a specific diet composition for PCOS with approaches including modifying protein, carbohydrate …
The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios.
Nordio M, Basciani S, Camajani E. Nordio M, et al. Eur Rev Med Pharmacol Sci. 2019 Jun;23(12):5512-5521. doi: 10.26355/eurrev_201906_18223. Eur Rev Med Pharmacol Sci. 2019. PMID: 31298405 Free article. Clinical Trial.
OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI), in the therapy of polycystic ovary syndrome (PCOS). ...They received 2 g …
OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, …
278 results