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108 results

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Page 1
Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines.
Fitz V, Graca S, Mahalingaiah S, Liu J, Lai L, Butt A, Armour M, Rao V, Naidoo D, Maunder A, Yang G, Vaddiparthi V, Witchel SF, Pena A, Spritzer PM, Li R, Tay C, Mousa A, Teede H, Ee C. Fitz V, et al. J Clin Endocrinol Metab. 2024 May 17;109(6):1630-1655. doi: 10.1210/clinem/dgad762. J Clin Endocrinol Metab. 2024. PMID: 38163998 Free PMC article.
CONTEXT: Insulin resistance is common in women with polycystic ovary syndrome (PCOS). Inositol may have insulin sensitizing effects; however, its efficacy in the management of PCOS remains indeterminate. ...DATA SYNTHESIS: Thirteen comparisons were assessed, …
CONTEXT: Insulin resistance is common in women with polycystic ovary syndrome (PCOS). Inositol may have insulin sensitizing ef …
The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios.
Nordio M, Basciani S, Camajani E. Nordio M, et al. Eur Rev Med Pharmacol Sci. 2019 Jun;23(12):5512-5521. doi: 10.26355/eurrev_201906_18223. Eur Rev Med Pharmacol Sci. 2019. PMID: 31298405 Free article. Clinical Trial.
OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI), in the therapy of polycystic ovary syndrome (PCOS). ...RESULTS: We found …
OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, …
Comparative efficacy of combined myo-inositol and D-chiro inositol versus metformin across PCOS Phenotypes: enhancing ovarian function, ovulation, and stress response in a prospective clinical trial.
Gul M, Khan H, Rauf B, Bukhari SMS, Ehtesham E, Malik MO, Shah FA, Alanazi FE, Shah M. Gul M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jul;398(7):8761-8772. doi: 10.1007/s00210-025-03813-9. Epub 2025 Jan 23. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39847053 Clinical Trial.
This study aimed to evaluate the comparative efficacy of Myo-inositol (MI) and D-chiro-inositol (DCI) with metformin in enhancing ovarian function, promoting ovulation, and reducing perceived stress in patients with polycystic ovary syndrome (PCOS). Wo …
This study aimed to evaluate the comparative efficacy of Myo-inositol (MI) and D-chiro-inositol (DCI) with metformin in enhanc …
Polycystic ovarian syndrome-current pharmacotherapy and clinical implications.
Rashid R, Mir SA, Kareem O, Ali T, Ara R, Malik A, Amin F, Bader GN. Rashid R, et al. Taiwan J Obstet Gynecol. 2022 Jan;61(1):40-50. doi: 10.1016/j.tjog.2021.11.009. Taiwan J Obstet Gynecol. 2022. PMID: 35181044 Free article. Review.
However, the management of PCOS is challenging and current interventions are not able to deal with outcomes of this syndrome. This review encompasses latest pharmacotherapeutic and non-pharmacotherapeutic interventions currently in use to tackle various symptomatic content …
However, the management of PCOS is challenging and current interventions are not able to deal with outcomes of this syndrome. This re …
Inositols in PCOS.
Kamenov Z, Gateva A. Kamenov Z, et al. Molecules. 2020 Nov 27;25(23):5566. doi: 10.3390/molecules25235566. Molecules. 2020. PMID: 33260918 Free PMC article. Review.
Both inositols have a role in insulin signaling and hormonal synthesis in the ovaries. (2) Methods: Literature search (with key words: inositols, myo-inositol, d-chiro-inositol, PCOS) was done in PubMed until Sept. 2020 and 197 articles were ide …
Both inositols have a role in insulin signaling and hormonal synthesis in the ovaries. (2) Methods: Literature search (with key words …
Management of women with PCOS using myo-inositol and folic acid. New clinical data and review of the literature.
Regidor PA, Schindler AE, Lesoine B, Druckman R. Regidor PA, et al. Horm Mol Biol Clin Investig. 2018 Mar 2;34(2):/j/hmbci.2018.34.issue-2/hmbci-2017-0067/hmbci-2017-0067.xml. doi: 10.1515/hmbci-2017-0067. Horm Mol Biol Clin Investig. 2018. PMID: 29498933 Review.
Discussion Myo-inositol has proven to be a new treatment option for patients with PCOS and infertility. ...Therefore, myo-inositol also represents an improvement in IVF protocols for patients with PCOS....
Discussion Myo-inositol has proven to be a new treatment option for patients with PCOS and infertility. ...Therefore, myo-i
Women with PCOS who undergo IVF: a comprehensive review of therapeutic strategies for successful outcomes.
Kotlyar AM, Seifer DB. Kotlyar AM, et al. Reprod Biol Endocrinol. 2023 Aug 1;21(1):70. doi: 10.1186/s12958-023-01120-7. Reprod Biol Endocrinol. 2023. PMID: 37528417 Free PMC article. Review.
Polycystic ovarian syndrome (PCOS) is a widespread syndrome that poses unique challenges and constraints to the field of assisted reproductive technology. ...However, newer stimulated FET protocols using Letrozole may offer improved outcomes. Overall, patients with PCOS
Polycystic ovarian syndrome (PCOS) is a widespread syndrome that poses unique challenges and constraints to the field of assisted rep …
Inositol Treatment for PCOS Should Be Science-Based and Not Arbitrary.
Roseff S, Montenegro M. Roseff S, et al. Int J Endocrinol. 2020 Mar 27;2020:6461254. doi: 10.1155/2020/6461254. eCollection 2020. Int J Endocrinol. 2020. PMID: 32308679 Free PMC article. Review.
Therefore, the inositol supplements used in PCOS treatment must be carefully defined. Clinical evidence has demonstrated that the 40 : 1 ratio between myo-inositol and D-chiro-inositol is the optimal combination to restore ovulation in PCOS
Therefore, the inositol supplements used in PCOS treatment must be carefully defined. Clinical evidence has demonstrated that …
Comparison of metformin plus myoinositol vs metformin alone in PCOS women undergoing ovulation induction cycles: randomized controlled trial.
Agrawal A, Mahey R, Kachhawa G, Khadgawat R, Vanamail P, Kriplani A. Agrawal A, et al. Gynecol Endocrinol. 2019 Jun;35(6):511-514. doi: 10.1080/09513590.2018.1549656. Epub 2019 Jan 7. Gynecol Endocrinol. 2019. PMID: 30614289 Clinical Trial.
The present study was planned to evaluate the benefit of synergetic effect of Metformin plus Myo-inositol versus Metformin alone in infertile polycystic ovarian syndrome (PCOS) women undergoing ovulation induction. One hundred and twenty infertile PCOS
The present study was planned to evaluate the benefit of synergetic effect of Metformin plus Myo-inositol versus Metformin alone in i …
Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management.
Muhammed Saeed AA, Noreen S, Awlqadr FH, Farooq MI, Qadeer M, Rai N, Farag HA, Saeed MN. Muhammed Saeed AA, et al. J Health Popul Nutr. 2025 May 2;44(1):143. doi: 10.1186/s41043-025-00899-y. J Health Popul Nutr. 2025. PMID: 40317096 Free PMC article. Review.
This detailed review focuses on dietary strategies, macromolecules, macromolecules, and herbal interventions that exception-ally work in PCOS treatment. Research has shown that Mediterranean, low-glycemic index, and ketogenic diets that are modified with individuals in min …
This detailed review focuses on dietary strategies, macromolecules, macromolecules, and herbal interventions that exception-ally work in …
108 results