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Year Number of Results
2014 4
2015 15
2016 19
2017 16
2018 19
2019 15
2020 12
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Deep learning enables rapid identification of potent DDR1 kinase inhibitors.
Zhavoronkov A, Ivanenkov YA, Aliper A, Veselov MS, Aladinskiy VA, Aladinskaya AV, Terentiev VA, Polykovskiy DA, Kuznetsov MD, Asadulaev A, Volkov Y, Zholus A, Shayakhmetov RR, Zhebrak A, Minaeva LI, Zagribelnyy BA, Lee LH, Soll R, Madge D, Xing L, Guo T, Aspuru-Guzik A. Zhavoronkov A, et al. Nat Biotechnol. 2019 Sep;37(9):1038-1040. doi: 10.1038/s41587-019-0224-x. Epub 2019 Sep 2. Nat Biotechnol. 2019. PMID: 31477924
Aging and drug discovery.
Bakula D, Aliper AM, Mamoshina P, Petr MA, Teklu A, Baur JA, Campisi J, Ewald CY, Georgievskaya A, Gladyshev VN, Kovalchuk O, Lamming DW, Luijsterburg MS, Martín-Montalvo A, Maudsley S, Mkrtchyan GV, Moskalev A, Olshansky SJ, Ozerov IV, Pickett A, Ristow M, Zhavoronkov A, Scheibye-Knudsen M. Bakula D, et al. Aging (Albany NY). 2018 Nov 13;10(11):3079-3088. doi: 10.18632/aging.101646. Aging (Albany NY). 2018. PMID: 30425188 Free PMC article.
Latest advances in aging research and drug discovery.
Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M. Bakula D, et al. Aging (Albany NY). 2019 Nov 21;11(22):9971-9981. doi: 10.18632/aging.102487. Epub 2019 Nov 21. Aging (Albany NY). 2019. PMID: 31770722 Free PMC article.
To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a community of Key Opinion Leaders (KOLs) in these areas and launched the annual conference series titled "Aging Research and Drug Discovery ( …
To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a …
Applications of Deep Learning in Biomedicine.
Mamoshina P, Vieira A, Putin E, Zhavoronkov A. Mamoshina P, et al. Mol Pharm. 2016 May 2;13(5):1445-54. doi: 10.1021/acs.molpharmaceut.5b00982. Epub 2016 Mar 29. Mol Pharm. 2016. PMID: 27007977 Review.
Towards natural mimetics of metformin and rapamycin.
Aliper A, Jellen L, Cortese F, Artemov A, Karpinsky-Semper D, Moskalev A, Swick AG, Zhavoronkov A. Aliper A, et al. Aging (Albany NY). 2017 Nov 15;9(11):2245-2268. doi: 10.18632/aging.101319. Aging (Albany NY). 2017. PMID: 29165314 Free PMC article.
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy.
Ravi R, Noonan KA, Pham V, Bedi R, Zhavoronkov A, Ozerov IV, Makarev E, V Artemov A, Wysocki PT, Mehra R, Nimmagadda S, Marchionni L, Sidransky D, Borrello IM, Izumchenko E, Bedi A. Ravi R, et al. Nat Commun. 2018 Feb 21;9(1):741. doi: 10.1038/s41467-017-02696-6. Nat Commun. 2018. PMID: 29467463 Free PMC article.
Immune profiles in primary squamous cell carcinoma of the head and neck.
Saloura V, Izumchenko E, Zuo Z, Bao R, Korzinkin M, Ozerov I, Zhavoronkov A, Sidransky D, Bedi A, Hoque MO, Koeppen H, Keck MK, Khattri A, London N, Kotlov N, Fatima A, Vougiouklakis T, Nakamura Y, Lingen M, Agrawal N, Savage PA, Kron S, Kline J, Kowanetz M, Seiwert TY. Saloura V, et al. Oral Oncol. 2019 Sep;96:77-88. doi: 10.1016/j.oraloncology.2019.06.032. Epub 2019 Jul 12. Oral Oncol. 2019. PMID: 31422218
Artificial intelligence for aging and longevity research: Recent advances and perspectives.
Zhavoronkov A, Mamoshina P, Vanhaelen Q, Scheibye-Knudsen M, Moskalev A, Aliper A. Zhavoronkov A, et al. Ageing Res Rev. 2019 Jan;49:49-66. doi: 10.1016/j.arr.2018.11.003. Epub 2018 Nov 22. Ageing Res Rev. 2019. PMID: 30472217 Free article. Review.
Reversibility of irreversible aging.
Galkin F, Zhang B, Dmitriev SE, Gladyshev VN. Galkin F, et al. Ageing Res Rev. 2019 Jan;49:104-114. doi: 10.1016/j.arr.2018.11.008. Epub 2018 Dec 1. Ageing Res Rev. 2019. PMID: 30513346 Review.
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