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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1983 1
1985 3
1986 1
1987 1
1988 1
1990 3
1991 5
1992 2
1993 5
1994 4
1995 13
1996 19
1997 27
1998 22
1999 22
2000 22
2001 27
2002 15
2003 30
2004 15
2005 40
2006 32
2007 47
2008 57
2009 70
2010 50
2011 43
2012 77
2013 60
2014 63
2015 54
2016 55
2017 50
2018 63
2019 82
2020 93
2021 90
2022 104
2023 99
2024 100
2025 135
2026 76

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1,605 results

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Page 1
Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
Choi K, Lee YJ, Park S, Je NK, Suh HS. Choi K, et al. Sleep Med Rev. 2022 Dec;66:101692. doi: 10.1016/j.smrv.2022.101692. Epub 2022 Sep 13. Sleep Med Rev. 2022. PMID: 36179487
Due to heterogeneity, we conducted subgroup analyses by age group. In non-comorbid insomnia, melatonin was only significantly effective in sleep onset latency and total sleep time in children and adolescents. ...In comorbid insomnia, melatoni …
Due to heterogeneity, we conducted subgroup analyses by age group. In non-comorbid insomnia, melatonin was only significantly …
European expert guidance on management of sleep onset insomnia and melatonin use in typically developing children.
Bruni O, Breda M, Nobili L, Fietze I, Capdevila ORS, Gronfier C. Bruni O, et al. Eur J Pediatr. 2024 Jul;183(7):2955-2964. doi: 10.1007/s00431-024-05556-w. Epub 2024 Apr 16. Eur J Pediatr. 2024. PMID: 38625388 Free PMC article. Review.
When sleep onset insomnia is present in otherwise healthy children, the management should follow a stepwise approach. ...Conclusion: Low-dose melatonin is a useful strategy for managing sleep onset insomnia in healthy children who have not impro …
When sleep onset insomnia is present in otherwise healthy children, the management should follow a stepwise approach. ...Concl …
Melatonin in sleep disorders.
Poza JJ, Pujol M, Ortega-Albás JJ, Romero O; Insomnia Study Group of the Spanish Sleep Society (SES). Poza JJ, et al. Neurologia (Engl Ed). 2022 Sep;37(7):575-585. doi: 10.1016/j.nrleng.2018.08.004. Epub 2020 Sep 18. Neurologia (Engl Ed). 2022. PMID: 36064286 Free article. Review.
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administered orally, which has led to interest in its use as a treatment for insomnia. Moreover, as production of the hormone decreases with a …
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administe …
The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Riemann D, Espie CA, Altena E, Arnardottir ES, Baglioni C, Bassetti CLA, Bastien C, Berzina N, Bjorvatn B, Dikeos D, Dolenc Groselj L, Ellis JG, Garcia-Borreguero D, Geoffroy PA, Gjerstad M, Gonçalves M, Hertenstein E, Hoedlmoser K, Hion T, Holzinger B, Janku K, Jansson-Fröjmark M, Järnefelt H, Jernelöv S, Jennum PJ, Khachatryan S, Krone L, Kyle SD, Lancee J, Leger D, Lupusor A, Marques DR, Nissen C, Palagini L, Paunio T, Perogamvros L, Pevernagie D, Schabus M, Shochat T, Szentkiralyi A, Van Someren E, van Straten A, Wichniak A, Verbraecken J, Spiegelhalder K. Riemann D, et al. J Sleep Res. 2023 Dec;32(6):e14035. doi: 10.1111/jsr.14035. J Sleep Res. 2023. PMID: 38016484 Free article. Review.
Progress in the field of insomnia since 2017 necessitated this update of the European Insomnia Guideline. Recommendations for the diagnostic procedure for insomnia and its comorbidities are: clinical interview (encompassing sleep and medical history); …
Progress in the field of insomnia since 2017 necessitated this update of the European Insomnia Guideline. Recommendations for …
Efficacy of melatonin and ramelteon for the acute and long-term management of insomnia disorder in adults: A systematic review and meta-analysis.
Maruani J, Reynaud E, Chambe J, Palagini L, Bourgin P, Geoffroy PA. Maruani J, et al. J Sleep Res. 2023 Dec;32(6):e13939. doi: 10.1111/jsr.13939. Epub 2023 Jul 11. J Sleep Res. 2023. PMID: 37434463
Melatonin has gained growing interest as a treatment of insomnia, despite contradictory findings, and a low level of evidence. A systematic review and meta-analysis was conducted following PRISMA criteria, to assess the efficacy of melatonin and ramelteon com …
Melatonin has gained growing interest as a treatment of insomnia, despite contradictory findings, and a low level of evidence. …
Insomnia in children affected by autism spectrum disorder: The role of melatonin in treatment.
Bruni O, Biggio G, Malorgio E, Nobili L. Bruni O, et al. Sleep Med. 2024 Jul;119:511-517. doi: 10.1016/j.sleep.2024.05.046. Epub 2024 May 24. Sleep Med. 2024. PMID: 38805858 Review.
Recent data show that melatonin-based formulations are effective and safe for treating ASD-related insomnia both short and long term. ...Current guidelines recommend managing insomnia and sleep disturbances in ASD using a combination of behavioral and …
Recent data show that melatonin-based formulations are effective and safe for treating ASD-related insomnia both short and lon …
European guideline for the diagnosis and treatment of insomnia.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K. Riemann D, et al. J Sleep Res. 2017 Dec;26(6):675-700. doi: 10.1111/jsr.12594. Epub 2017 Sep 5. J Sleep Res. 2017. PMID: 28875581
This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, with the aim of providing clinical recommendations for the management of adult patients with insomnia. ...Polysomnography …
This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Resear …
[Melatonin for children with insomnia].
Berring-Uldum A, Debes NMM, Pedersen CR, Holst H. Berring-Uldum A, et al. Ugeskr Laeger. 2018 May 7;180(19):V08170628. Ugeskr Laeger. 2018. PMID: 29761771 Free article. Review. Danish.
Treatment for insomnia with melatonin (MT) in children and adolescents aged 0-17 years has doubled since 2011. ...Recent clinical trials indicate, that MT only has a clinical effect on sleep latency, not on total sleep time. Furthermore, it has emerged …
Treatment for insomnia with melatonin (MT) in children and adolescents aged 0-17 years has doubled since 2011. ...Recent clini …
Efficacy of melatonin for sleep disturbance in middle-aged primary insomnia: a double-blind, randomised clinical trial.
Xu H, Zhang C, Qian Y, Zou J, Li X, Liu Y, Zhu H, Meng L, Liu S, Zhang W, Yi H, Guan J, Chen Z, Yin S. Xu H, et al. Sleep Med. 2020 Dec;76:113-119. doi: 10.1016/j.sleep.2020.10.018. Epub 2020 Oct 17. Sleep Med. 2020. PMID: 33157425 Clinical Trial.
BACKGROUND: The aim of this study was to determine the efficacy of exogenous melatonin supplementation for sleep disturbances in patients with middle-aged primary insomnia. ...However, melatonin had no significant effect on other objective sleep …
BACKGROUND: The aim of this study was to determine the efficacy of exogenous melatonin supplementation for sleep disturbances …
Melatonin in sleep disorders.
Poza JJ, Pujol M, Ortega-Albás JJ, Romero O; en representación del Grupo de estudio de insomnio de la Sociedad Española de Sueño (SES). Poza JJ, et al. Neurologia (Engl Ed). 2022 Sep;37(7):575-585. doi: 10.1016/j.nrl.2018.08.002. Epub 2018 Nov 19. Neurologia (Engl Ed). 2022. PMID: 30466801 Free article. Review. English, Spanish.
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administered orally, which has led to interest in its use as a treatment for insomnia. Moreover, as production of the hormone decreases with a …
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administe …
1,605 results