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Did you mean insulin resistant alzheimer (2,684 results)?
Insulin Resistance and Diabetes Mellitus in Alzheimer's Disease.
Burillo J, Marqués P, Jiménez B, González-Blanco C, Benito M, Guillén C. Burillo J, et al. Cells. 2021 May 18;10(5):1236. doi: 10.3390/cells10051236. Cells. 2021. PMID: 34069890 Free PMC article. Review.
Type 2 diabetes mellitus is a progressive disease that is characterized by the appearance of insulin resistance. The term insulin resistance is very wide and could affect different proteins involved in insulin signaling, as well as other …
Type 2 diabetes mellitus is a progressive disease that is characterized by the appearance of insulin resistance. The te …
Insulin and Insulin Resistance in Alzheimer's Disease.
Sędzikowska A, Szablewski L. Sędzikowska A, et al. Int J Mol Sci. 2021 Sep 15;22(18):9987. doi: 10.3390/ijms22189987. Int J Mol Sci. 2021. PMID: 34576151 Free PMC article. Review.
Insulin is also able to freely cross the blood-brain barrier from the circulation. In addition, changes in insulin signaling, caused inter alia insulin resistance, may accelerate brain aging, and affect plasticity and possibly neurodegeneration. ...The …
Insulin is also able to freely cross the blood-brain barrier from the circulation. In addition, changes in insulin signaling, …
Brain insulin resistance in Alzheimer's disease and related disorders: mechanisms and therapeutic approaches.
Kellar D, Craft S. Kellar D, et al. Lancet Neurol. 2020 Sep;19(9):758-766. doi: 10.1016/S1474-4422(20)30231-3. Epub 2020 Jul 27. Lancet Neurol. 2020. PMID: 32730766 Free PMC article. Review.
Insulin also has a role in proteostasis, influencing clearance of the amyloid beta peptide and phosphorylation of tau, which are hallmarks of Alzheimer's disease. ...Through these multiple pathways, insulin dysregulation could contribute to neur …
Insulin also has a role in proteostasis, influencing clearance of the amyloid beta peptide and phosphorylation of tau, which are hall …
Insulin resistance, cognition, and Alzheimer disease.
Kim AB, Arvanitakis Z. Kim AB, et al. Obesity (Silver Spring). 2023 Jun;31(6):1486-1498. doi: 10.1002/oby.23761. Obesity (Silver Spring). 2023. PMID: 37203336 Free PMC article. Review.
Dementia, often due to multiple etiologies including Alzheimer disease (AD), is at the forefront. Previous studies have reported higher rates of dementia among persons with diabetes, yet less is known about how insulin resistance relates to cognition. …
Dementia, often due to multiple etiologies including Alzheimer disease (AD), is at the forefront. Previous studies have report …
Insulin resistance in Alzheimer's disease: The genetics and metabolomics links.
Amin AM, Mostafa H, Khojah HMJ. Amin AM, et al. Clin Chim Acta. 2023 Jan 15;539:215-236. doi: 10.1016/j.cca.2022.12.016. Epub 2022 Dec 22. Clin Chim Acta. 2023. PMID: 36566957 Free article. Review.
Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic burden worldwide. Although genetics and environmental factors play a role, AD is highly associated with insulin resistance (IR) disorders such as metab …
Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic burden worldwide. Althoug …
Insulin Resistance at the Crossroad of Alzheimer Disease Pathology: A Review.
Berlanga-Acosta J, Guillén-Nieto G, Rodríguez-Rodríguez N, Bringas-Vega ML, García-Del-Barco-Herrera D, Berlanga-Saez JO, García-Ojalvo A, Valdés-Sosa MJ, Valdés-Sosa PA. Berlanga-Acosta J, et al. Front Endocrinol (Lausanne). 2020 Nov 5;11:560375. doi: 10.3389/fendo.2020.560375. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33224105 Free PMC article. Review.
Insulin resistance and impaired cerebral glucose metabolism are invariantly reported in Alzheimer's disease (AD) and other neurodegenerative processes. ...As a bridge between AD and type 2 diabetes, activation of c-Jun N-terminal kinase (JNK) pa …
Insulin resistance and impaired cerebral glucose metabolism are invariantly reported in Alzheimer's disease …
Insulin resistance: a connecting link between Alzheimer's disease and metabolic disorder.
Kshirsagar V, Thingore C, Juvekar A. Kshirsagar V, et al. Metab Brain Dis. 2021 Jan;36(1):67-83. doi: 10.1007/s11011-020-00622-2. Epub 2020 Sep 28. Metab Brain Dis. 2021. PMID: 32986168 Review.
Recent evidence suggests that Alzheimer's disease (AD) is closely linked with insulin resistance, as seen in type 2 diabetes mellitus (T2DM). Insulin signaling is impaired in AD brains due to insulin resistance, ultimately r …
Recent evidence suggests that Alzheimer's disease (AD) is closely linked with insulin resistance, as seen …
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE. Talbot K, et al. J Clin Invest. 2012 Apr;122(4):1316-38. doi: 10.1172/JCI59903. J Clin Invest. 2012. PMID: 22476197 Free PMC article.
While a potential causal factor in Alzheimer's disease (AD), brain insulin resistance has not been demonstrated directly in that disorder. ...In the HF, these candidate biomarkers of brain insulin resistance increased commonly and …
While a potential causal factor in Alzheimer's disease (AD), brain insulin resistance has not been demons …
Insulin resistance in Alzheimer's disease.
Diehl T, Mullins R, Kapogiannis D. Diehl T, et al. Transl Res. 2017 May;183:26-40. doi: 10.1016/j.trsl.2016.12.005. Epub 2016 Dec 13. Transl Res. 2017. PMID: 28034760 Free PMC article. Review.
The links between systemic insulin resistance (IR), brain-specific IR, and Alzheimer's disease (AD) have been an extremely productive area of current research. ...Ultimately, examining the relation between IR and AD can be seen as a means of adv …
The links between systemic insulin resistance (IR), brain-specific IR, and Alzheimer's disease (AD) have …
Role of Insulin Resistance in the Alzheimer's Disease Progression.
Nguyen TT, Ta QTH, Nguyen TTD, Le TT, Vo VG. Nguyen TT, et al. Neurochem Res. 2020 Jul;45(7):1481-1491. doi: 10.1007/s11064-020-03031-0. Epub 2020 Apr 20. Neurochem Res. 2020. PMID: 32314178 Review.
Recent studies continue to find evidence linking Type 2 diabetes (T2D) with Alzheimer's disease (AD), the most common cause of dementia, a general term for memory loss and other cognitive abilities serious enough to interfere with daily life. ...The current w …
Recent studies continue to find evidence linking Type 2 diabetes (T2D) with Alzheimer's disease (AD), the most common c …
2,595 results