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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
1966 2
1967 4
1968 6
1969 2
1970 5
1971 7
1972 6
1973 2
1974 16
1975 13
1976 21
1977 17
1978 18
1979 35
1980 46
1981 47
1982 71
1983 60
1984 83
1985 84
1986 111
1987 149
1988 146
1989 153
1990 187
1991 220
1992 193
1993 236
1994 317
1995 365
1996 336
1997 328
1998 399
1999 396
2000 378
2001 363
2002 422
2003 520
2004 615
2005 673
2006 687
2007 854
2008 906
2009 980
2010 935
2011 1117
2012 1137
2013 1296
2014 1304
2015 1333
2016 1417
2017 1383
2018 1314
2019 1259
2020 1348
2021 1359
2022 1207
2023 1056
2024 1103
2025 480

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25,833 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Unknown field was ignored: [human genetically engineered]
Page 1
Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU.
Gunst J, Debaveye Y, Güiza F, Dubois J, De Bruyn A, Dauwe D, De Troy E, Casaer MP, De Vlieger G, Haghedooren R, Jacobs B, Meyfroidt G, Ingels C, Muller J, Vlasselaers D, Desmet L, Mebis L, Wouters PJ, Stessel B, Geebelen L, Vandenbrande J, Brands M, Gruyters I, Geerts E, De Pauw I, Vermassen J, Peperstraete H, Hoste E, De Waele JJ, Herck I, Depuydt P, Wilmer A, Hermans G, Benoit DD, Van den Berghe G; TGC-Fast Collaborators. Gunst J, et al. N Engl J Med. 2023 Sep 28;389(13):1180-1190. doi: 10.1056/NEJMoa2304855. N Engl J Med. 2023. PMID: 37754283 Clinical Trial.
Variation in the use of early parenteral nutrition and in insulin-induced severe hypoglycemia might explain this inconsistency. METHODS: We randomly assigned patients, on ICU admission, to liberal glucose control (insulin initiated only when the blood-glucose level …
Variation in the use of early parenteral nutrition and in insulin-induced severe hypoglycemia might explain this inconsistency. METHO …
The impact of soluble dietary fibre on gastric emptying, postprandial blood glucose and insulin in patients with type 2 diabetes.
Yu K, Ke MY, Li WH, Zhang SQ, Fang XC. Yu K, et al. Asia Pac J Clin Nutr. 2014;23(2):210-8. doi: 10.6133/apjcn.2014.23.2.01. Asia Pac J Clin Nutr. 2014. PMID: 24901089 Free article. Clinical Trial.
Dietary fibre plays an important role in controlling postprandial glycemic and insulin response in diabetic patients. The intake of dietary fibre has been shown to delay the gastric emptying in healthy subjects. ...SDF decreased postprandial glucose (p=0.001) and insuli …
Dietary fibre plays an important role in controlling postprandial glycemic and insulin response in diabetic patients. The intake of d …
Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.
Weng J, Li Y, Xu W, Shi L, Zhang Q, Zhu D, Hu Y, Zhou Z, Yan X, Tian H, Ran X, Luo Z, Xian J, Yan L, Li F, Zeng L, Chen Y, Yang L, Yan S, Liu J, Li M, Fu Z, Cheng H. Weng J, et al. Lancet. 2008 May 24;371(9626):1753-60. doi: 10.1016/S0140-6736(08)60762-X. Lancet. 2008. PMID: 18502299 Clinical Trial.
We did a multicentre, randomised trial to compare the effects of transient intensive insulin therapy (continuous subcutaneous insulin infusion [CSII] or multiple daily insulin injections [MDI]) with oral hypoglycaemic agents on beta-cell function and diabetes …
We did a multicentre, randomised trial to compare the effects of transient intensive insulin therapy (continuous subcutaneous insu …
Use of Voice-Based Conversational Artificial Intelligence for Basal Insulin Prescription Management Among Patients With Type 2 Diabetes: A Randomized Clinical Trial.
Nayak A, Vakili S, Nayak K, Nikolov M, Chiu M, Sosseinheimer P, Talamantes S, Testa S, Palanisamy S, Giri V, Schulman K. Nayak A, et al. JAMA Netw Open. 2023 Dec 1;6(12):e2340232. doi: 10.1001/jamanetworkopen.2023.40232. JAMA Netw Open. 2023. PMID: 38039007 Free PMC article. Clinical Trial.
IMPORTANCE: Optimizing insulin therapy for patients with type 2 diabetes can be challenging given the need for frequent dose adjustments. ...CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of a voice-based conversational AI application that provided autonomous …
IMPORTANCE: Optimizing insulin therapy for patients with type 2 diabetes can be challenging given the need for frequent dose adjustme …
'Human' insulin versus animal insulin in people with diabetes mellitus.
Richter B, Neises G. Richter B, et al. Cochrane Database Syst Rev. 2005 Jan 25;2005(1):CD003816. doi: 10.1002/14651858.CD003816.pub2. Cochrane Database Syst Rev. 2005. PMID: 15674916 Free PMC article. Review.
BACKGROUND: Human insulin was introduced for the routine treatment of diabetes mellitus in the early 1980s without adequate comparison of efficacy to animal insulin preparations. ...Insulin dose and insulin antibodies did not show relevant dissimilarit …
BACKGROUND: Human insulin was introduced for the routine treatment of diabetes mellitus in the early 1980s without adequate compariso …
Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus.
Chandalia M, Garg A, Lutjohann D, von Bergmann K, Grundy SM, Brinkley LJ. Chandalia M, et al. N Engl J Med. 2000 May 11;342(19):1392-8. doi: 10.1056/NEJM200005113421903. N Engl J Med. 2000. PMID: 10805824 Free article. Clinical Trial.
METHODS: In a randomized, crossover study, we assigned 13 patients with type 2 diabetes mellitus to follow two diets, each for six weeks: a diet containing moderate amounts of fiber (total, 24 g; 8 g of soluble fiber and 16 g of insoluble fiber), as recommended by the Amer …
METHODS: In a randomized, crossover study, we assigned 13 patients with type 2 diabetes mellitus to follow two diets, each for six weeks: a …
Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus.
Horvath K, Jeitler K, Berghold A, Ebrahim SH, Gratzer TW, Plank J, Kaiser T, Pieber TR, Siebenhofer A. Horvath K, et al. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD005613. doi: 10.1002/14651858.CD005613.pub3. Cochrane Database Syst Rev. 2007. Update in: Cochrane Database Syst Rev. 2020 Nov 9;11:CD005613. doi: 10.1002/14651858.CD005613.pub4. PMID: 17443605 Free article. Updated. Review.
Pooling of studies by means of random-effects meta-analyses was performed. MAIN RESULTS: Six studies comparing insulin glargine to NPH (Neutral Protamine Hagedorn) insulin and two studies comparing insulin detemir to NPH insulin were identified. In the …
Pooling of studies by means of random-effects meta-analyses was performed. MAIN RESULTS: Six studies comparing insulin glargine to NP …
Pre-meal insulin aspart compared with pre-meal soluble human insulin in type 1 diabetes.
Home PD, Hallgren P, Usadel KH, Sane T, Faber J, Grill V, Friberg HH. Home PD, et al. Diabetes Res Clin Pract. 2006 Feb;71(2):131-9. doi: 10.1016/j.diabres.2005.05.015. Epub 2005 Jul 27. Diabetes Res Clin Pract. 2006. PMID: 16054266 Clinical Trial.
The aim of the present 3-year study was to evaluate the long-term safety and efficacy of insulin aspart in people with type 1 diabetes. This was a 30-month extension of a multinational, multicentre, open-label, parallel-group study of 753 people with type 1 diabetes, origi …
The aim of the present 3-year study was to evaluate the long-term safety and efficacy of insulin aspart in people with type 1 diabete …
Recombinant DNA derived monomeric insulin analogue: comparison with soluble human insulin in normal subjects.
Vora JP, Owens DR, Dolben J, Atiea JA, Dean JD, Kang S, Burch A, Brange J. Vora JP, et al. BMJ. 1988 Nov 12;297(6658):1236-9. doi: 10.1136/bmj.297.6658.1236. BMJ. 1988. PMID: 3145064 Free PMC article. Clinical Trial.
OBJECTIVE: To compare the rate of absorption from subcutaneous tissue and the resulting hypoglycaemic effect of iodine-125 labelled soluble human insulin and a monomeric insulin analogue derived by recombinant DNA technology. ...The hypoglycaemic response to …
OBJECTIVE: To compare the rate of absorption from subcutaneous tissue and the resulting hypoglycaemic effect of iodine-125 labelled solub …
Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study.
Brock Jacobsen I, Vind BF, Korsholm L, Flyvbjerg A, Frystyk J, Holst JJ, Beck-Nielsen H, Henriksen JE. Brock Jacobsen I, et al. Acta Physiol (Oxf). 2011 Jul;202(3):337-47. doi: 10.1111/j.1748-1716.2011.02307.x. Acta Physiol (Oxf). 2011. PMID: 21481195 Clinical Trial.
Sixteen patients with type 1 diabetes were subjected to three daily injections of human soluble insulin or Aspart in addition to Neutral Protamine Hagedorn (NPH) insulin twice daily. ...Modest differences existed in the counter-regulatory responses regarding …
Sixteen patients with type 1 diabetes were subjected to three daily injections of human soluble insulin or Aspart in addition …
25,833 results
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