R-loop-dependent promoter-proximal termination ensures genome stability.
Xu C, Li C, Chen J, Xiong Y, Qiao Z, Fan P, Li C, Ma S, Liu J, Song A, Tao B, Xu T, Xu W, Chi Y, Xue J, Wang P, Ye D, Gu H, Zhang P, Wang Q, Xiao R, Cheng J, Zheng H, Yu X, Zhang Z, Wu J, Liang K, Liu YJ, Lu H, Chen FX.
Xu C, et al.
Nature. 2023 Sep;621(7979):610-619. doi: 10.1038/s41586-023-06515-5. Epub 2023 Aug 9.
Nature. 2023.
PMID: 37557913
Free PMC article.
Here we identify a stable association between the genome-stability regulator sensor of single-stranded DNA (SOSS)(3) and the transcription regulator Integrator-PP2A (INTAC)(4-6). Through SSB1-mediated recognition of single-stranded DNA, SOSS-INTAC stimulates promote …
Here we identify a stable association between the genome-stability regulator sensor of single-stranded DNA (SOSS)(3) and the transcription r …