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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1915 4
1916 2
1917 3
1919 1
1920 1
1921 4
1922 3
1923 2
1924 1
1926 5
1927 1
1928 1
1929 3
1930 3
1931 2
1932 5
1933 4
1934 5
1935 5
1936 6
1937 5
1938 3
1939 10
1940 9
1941 13
1942 8
1943 4
1944 8
1945 20
1946 33
1947 42
1948 46
1949 43
1950 59
1951 74
1952 54
1953 61
1954 85
1955 70
1956 79
1957 85
1958 81
1959 92
1960 80
1961 82
1962 100
1963 135
1964 137
1965 183
1966 197
1967 206
1968 267
1969 280
1970 271
1971 301
1972 378
1973 387
1974 451
1975 999
1976 1210
1977 1206
1978 1180
1979 1440
1980 1552
1981 1656
1982 1701
1983 2099
1984 2367
1985 2492
1986 2814
1987 2958
1988 3342
1989 4074
1990 4450
1991 4828
1992 5190
1993 5625
1994 6513
1995 7137
1996 7532
1997 7863
1998 8434
1999 8731
2000 9807
2001 10624
2002 11697
2003 12801
2004 15186
2005 17291
2006 19656
2007 21736
2008 24017
2009 26145
2010 29043
2011 32848
2012 36560
2013 40641
2014 48181
2015 54488
2016 59197
2017 63315
2018 68852
2019 74732
2020 87298
2021 101487
2022 108323
2023 110071
2024 44065

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1,106,003 results

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Page 1
HBV Integration Induces Complex Interactions between Host and Viral Genomic Functions at the Insertion Site.
Zhang D, Zhang K, Protzer U, Zeng C. Zhang D, et al. J Clin Transl Hepatol. 2021 Jun 28;9(3):399-408. doi: 10.14218/JCTH.2021.00062. Epub 2021 Apr 25. J Clin Transl Hepatol. 2021. PMID: 34221926 Free PMC article. Review.
Dissection of the genomic features surrounding integration sites will deepen our understanding of mechanisms underlying integration. ...Viral integrants can be single copy or multiple copies of different fragments with complicated rearrangement, which warrant …
Dissection of the genomic features surrounding integration sites will deepen our understanding of mechanisms underlying integratio …
The road towards data integration in human genomics: players, steps and interactions.
Bernasconi A, Canakoglu A, Masseroli M, Ceri S. Bernasconi A, et al. Brief Bioinform. 2021 Jan 18;22(1):30-44. doi: 10.1093/bib/bbaa080. Brief Bioinform. 2021. PMID: 32496509 Review.
In this paper, we first describe a technological pipeline from data production to data integration; we then propose a taxonomy of genomic data players (based on the distinction between contributors, repository hosts, consortia, integrators and consumers) and apply t …
In this paper, we first describe a technological pipeline from data production to data integration; we then propose a taxonomy of gen …
Human papillomavirus genome integration in squamous carcinogenesis: what have next-generation sequencing studies taught us?
Groves IJ, Coleman N. Groves IJ, et al. J Pathol. 2018 May;245(1):9-18. doi: 10.1002/path.5058. Epub 2018 Mar 30. J Pathol. 2018. PMID: 29443391 Review.
The advent of next-generation sequencing (NGS) of both RNA and DNA has allowed powerful interrogation of the association of HRHPVs with human disease, including precise determination of the sites of integration and the genomic rearrangements at integration loci. In …
The advent of next-generation sequencing (NGS) of both RNA and DNA has allowed powerful interrogation of the association of HRHPVs with huma …
Integration target site selection for retroviruses and transposable elements.
Wu X, Burgess SM. Wu X, et al. Cell Mol Life Sci. 2004 Oct;61(19-20):2588-96. doi: 10.1007/s00018-004-4206-9. Cell Mol Life Sci. 2004. PMID: 15526164 Review.
When a retrovirus infects a cell, its RNA genome is reverse transcribed into a double-stranded DNA, which is then permanently integrated into the host chromosome. Integration is one of the essential steps in the retroviral life cycle. ...It is a bit difficult to exp …
When a retrovirus infects a cell, its RNA genome is reverse transcribed into a double-stranded DNA, which is then permanently integrated …
Integration of high-risk human papillomavirus: a key event in cervical carcinogenesis?
Pett M, Coleman N. Pett M, et al. J Pathol. 2007 Aug;212(4):356-67. doi: 10.1002/path.2192. J Pathol. 2007. PMID: 17573670 Review.
The process of integration and subsequent clonal selection of integrants can therefore be considered as two independent and biologically distinct events. ...Care should be taken in interpreting studies of HPV integration frequency in clinical samples, as the …
The process of integration and subsequent clonal selection of integrants can therefore be considered as two independent and bi …
A sensory integration account for time perception.
Toso A, Fassihi A, Paz L, Pulecchi F, Diamond ME. Toso A, et al. PLoS Comput Biol. 2021 Jan 29;17(1):e1008668. doi: 10.1371/journal.pcbi.1008668. eCollection 2021 Jan. PLoS Comput Biol. 2021. PMID: 33513135 Free PMC article.
We modeled real spike trains recorded from vibrissal somatosensory cortex as input to dual leaky integrators-an intensity integrator with short time constant and a duration integrator with long time constant-generating neurometric functions that replicated th …
We modeled real spike trains recorded from vibrissal somatosensory cortex as input to dual leaky integrators-an intensity integrat …
SurVirus: a repeat-aware virus integration caller.
Rajaby R, Zhou Y, Meng Y, Zeng X, Li G, Wu P, Sung WK. Rajaby R, et al. Nucleic Acids Res. 2021 Apr 6;49(6):e33. doi: 10.1093/nar/gkaa1237. Nucleic Acids Res. 2021. PMID: 33444454 Free PMC article.
A significant portion of human cancers are due to viruses integrating into human genomes. Therefore, accurately predicting virus integrations can help uncover the mechanisms that lead to many devastating diseases. ...False alignments create false positives, while mi …
A significant portion of human cancers are due to viruses integrating into human genomes. Therefore, accurately predicting virus i …
Sustainability. Systems integration for global sustainability.
Liu J, Mooney H, Hull V, Davis SJ, Gaskell J, Hertel T, Lubchenco J, Seto KC, Gleick P, Kremen C, Li S. Liu J, et al. Science. 2015 Feb 27;347(6225):1258832. doi: 10.1126/science.1258832. Science. 2015. PMID: 25722418 Review.
Global sustainability challenges, from maintaining biodiversity to providing clean air and water, are closely interconnected yet often separately studied and managed. Systems integration-holistic approaches to integrating various components of coupled human and natu …
Global sustainability challenges, from maintaining biodiversity to providing clean air and water, are closely interconnected yet often separ …
scBridge embraces cell heterogeneity in single-cell RNA-seq and ATAC-seq data integration.
Li Y, Zhang D, Yang M, Peng D, Yu J, Liu Y, Lv J, Chen L, Peng X. Li Y, et al. Nat Commun. 2023 Sep 28;14(1):6045. doi: 10.1038/s41467-023-41795-5. Nat Commun. 2023. PMID: 37770437 Free PMC article.
Hence, unlike most existing works that homogeneously treat and integrate all cells, we propose a multi-omics data integration method (dubbed scBridge) that integrates cells in a heterogeneous manner. In brief, scBridge iterates between i) identifying reliable …
Hence, unlike most existing works that homogeneously treat and integrate all cells, we propose a multi-omics data integration …
Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis.
Matsubara K, Tokino T. Matsubara K, et al. Mol Biol Med. 1990 Jun;7(3):243-60. Mol Biol Med. 1990. PMID: 2170810 Review.
By means of structural analyses of the possible primary integrants, we deduced that the replication intermediates of the viral genome are the preferred substrates for integration. The integrated HBV DNA and the target cellular DNA are invariably associated wi …
By means of structural analyses of the possible primary integrants, we deduced that the replication intermediates of the viral genome …
1,106,003 results
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