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Table representation of search results timeline featuring number of search results per year.

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1974 1
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366 results

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Page 1
METTL3 regulates heterochromatin in mouse embryonic stem cells.
Xu W, Li J, He C, Wen J, Ma H, Rong B, Diao J, Wang L, Wang J, Wu F, Tan L, Shi YG, Shi Y, Shen H. Xu W, et al. Nature. 2021 Mar;591(7849):317-321. doi: 10.1038/s41586-021-03210-1. Epub 2021 Jan 27. Nature. 2021. PMID: 33505026
METTL3 predominantly localizes to the intracisternal A particle (IAP)-type family of endogenous retroviruses. Knockout of Mettl3 impairs the deposition of multiple heterochromatin marks onto METTL3-targeted IAPs, and upregulates IAP transcription, suggesting …
METTL3 predominantly localizes to the intracisternal A particle (IAP)-type family of endogenous retroviruses. Knockout …
m6A RNA methylation regulates the fate of endogenous retroviruses.
Chelmicki T, Roger E, Teissandier A, Dura M, Bonneville L, Rucli S, Dossin F, Fouassier C, Lameiras S, Bourc'his D. Chelmicki T, et al. Nature. 2021 Mar;591(7849):312-316. doi: 10.1038/s41586-020-03135-1. Epub 2021 Jan 13. Nature. 2021. PMID: 33442060
Methylation of ERV mRNAs is catalysed by the complex of methyltransferase-like METTL3-METTL14(4) proteins, and we found that depletion of METTL3-METTL14, along with their accessory subunits WTAP and ZC3H13, led to increased mRNA abundance of intracisternal A-particles (IAP …
Methylation of ERV mRNAs is catalysed by the complex of methyltransferase-like METTL3-METTL14(4) proteins, and we found that depletion of ME …
Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene.
Mori M, Liu C, Yoshizawa T, Miyahara H, Dai J, Igarashi Y, Cui X, Li Y, Kang X, Higuchi K. Mori M, et al. Mamm Genome. 2022 Sep;33(3):451-464. doi: 10.1007/s00335-021-09926-9. Epub 2022 Jan 24. Mamm Genome. 2022. PMID: 35067752
We then investigated the Prss53 gene and discovered that NCT has an insertion of an intracisternal A particle element in the first intron of the gene. Nevertheless, the expression of the Prss53 is not altered in the NCT skin both in transcript and protein lev …
We then investigated the Prss53 gene and discovered that NCT has an insertion of an intracisternal A particle element i …
Abnormal activation of cytokine gene expression by intracisternal type A particle transposition: effects of mutations that result in autocrine growth stimulation and malignant transformation.
Wang XY, Steelman LS, McCubrey JA. Wang XY, et al. Cytokines Cell Mol Ther. 1997 Mar;3(1):3-19. Cytokines Cell Mol Ther. 1997. PMID: 9287239 Review.
This review will focus on understanding the mechanisms resulting in the deregulated expression of cytokine genes that can lead to autocrine transformation. The murine genome contains over 2000 copies of intracisternal type A particles (IAPs), which under certain cir …
This review will focus on understanding the mechanisms resulting in the deregulated expression of cytokine genes that can lead to aut …
Intracisternal A-particle genes in Mus musculus: a conserved family of retrovirus-like elements.
Kuff EL, Smith LA, Lueders KK. Kuff EL, et al. Mol Cell Biol. 1981 Mar;1(3):216-27. doi: 10.1128/mcb.1.3.216-227.1981. Mol Cell Biol. 1981. PMID: 6821514 Free PMC article.
The structural organization of intracisternal A-particle genes has been studied, using isolates from a mouse gene library in lambda phage Charon 4A. ...A-particle genes varied in the occurrence of specific restriction sites at char …
The structural organization of intracisternal A-particle genes has been studied, using isolates from a mouse gen …
Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice.
Maeda-Smithies N, Hiller S, Dong S, Kim HS, Bennett BJ, Kayashima Y. Maeda-Smithies N, et al. Mamm Genome. 2020 Feb;31(1-2):2-16. doi: 10.1007/s00335-019-09824-1. Epub 2020 Jan 7. Mamm Genome. 2020. PMID: 31912264 Free PMC article.
We found a retrovirus-derived transposable element, intracisternal A particle (IAP), in the promoter region of Stab2(DBA) which likely interferes with normal expression in the LSECs. ...Chr13:59.9-73 Mb contains a large number of genes encoding Kruppel …
We found a retrovirus-derived transposable element, intracisternal A particle (IAP), in the promoter region of Stab2(DB …
Expression of an intracisternal A-particle-like element in rat ovary.
Graham KM, Ko C, Park KS, Sarge K, Park-Sarge OK. Graham KM, et al. Biochem Biophys Res Commun. 2000 Nov 11;278(1):48-57. doi: 10.1006/bbrc.2000.3759. Biochem Biophys Res Commun. 2000. PMID: 11071854
We have isolated a rat intracisternal-A particle element (IAP)-like element (IAP-LE) from ovarian granulosa cells that appears to be identical to the rat EST clone AA964260. ...
We have isolated a rat intracisternal-A particle element (IAP)-like element (IAP-LE) from ovarian granulosa cells that …
Terminally redundant sequences in cellular intracisternal A-particle genes.
Cole MD, Ono M, Huang RC. Cole MD, et al. J Virol. 1981 May;38(2):680-7. doi: 10.1128/JVI.38.2.680-687.1981. J Virol. 1981. PMID: 7241664 Free PMC article.
We showed that different intracisternal A-particle genes had a terminally redundant sequence of about 400 base pairs, one-half of which arose from the 3' end of the intracisternal A-particle RNA. ...This indicated that the initial …
We showed that different intracisternal A-particle genes had a terminally redundant sequence of about 400 base p …
The mouse intracisternal A particle-promoted placental gene retrotransposition is mouse-strain-specific.
Chang-Yeh A, Mold DE, Brilliant MH, Huang RC. Chang-Yeh A, et al. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):292-6. doi: 10.1073/pnas.90.1.292. Proc Natl Acad Sci U S A. 1993. PMID: 7678343 Free PMC article.
Insertion of a single long terminal repeat (LTR) of an intracisternal A particle (IAP) gene into a placenta-expressed cellular gene (mouse IAP-promoted placental gene, MIPP) has recently been found for the mouse strains Swiss and CF-1. ...
Insertion of a single long terminal repeat (LTR) of an intracisternal A particle (IAP) gene into a placenta-expressed c …
366 results