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578 results

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Intraepidermal Nerve Fiber Density as Measured by Skin Punch Biopsy as a Marker for Small Fiber Neuropathy: Application in Patients with Fibromyalgia.
Kelley MA, Hackshaw KV. Kelley MA, et al. Diagnostics (Basel). 2021 Mar 17;11(3):536. doi: 10.3390/diagnostics11030536. Diagnostics (Basel). 2021. PMID: 33802768 Free PMC article. Review.
Small fiber neuropathy (SFN) is a type of peripheral neuropathy that occurs from damage to the small A-delta and C nerve fibers that results in the clinical condition known as SFN. ...The skin punch biopsy provides an objective tool for use in q …
Small fiber neuropathy (SFN) is a type of peripheral neuropathy that occurs from damage to the small A-delta and C nerve fi …
European Federation of Neurological Societies/Peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society.
Lauria G, Hsieh ST, Johansson O, Kennedy WR, Leger JM, Mellgren SI, Nolano M, Merkies IS, Polydefkis M, Smith AG, Sommer C, Valls-Solé J; European Federation of Neurological Societies; Peripheral Nerve Society. Lauria G, et al. Eur J Neurol. 2010 Jul;17(7):903-12, e44-9. doi: 10.1111/j.1468-1331.2010.03023.x. Eur J Neurol. 2010. PMID: 20642627 Free article.
Most of the new studies focused on small fiber neuropathy (SFN), a subtype of neuropathy for which the diagnosis was first developed through skin biopsy examination. ...After a consensus meeting, the task force members created a manuscript that was subsequent …
Most of the new studies focused on small fiber neuropathy (SFN), a subtype of neuropathy for which the diagnosis was first developed …
Small fiber neuropathy.
Finsterer J, Scorza FA. Finsterer J, et al. Acta Neurol Scand. 2022 May;145(5):493-503. doi: 10.1111/ane.13591. Epub 2022 Feb 7. Acta Neurol Scand. 2022. PMID: 35130356 Review.
Small fiber neuropathy (SFN) is a peripheral nervous system disease due to affection of A-delta or C-fibers in a proximal, distal, or diffuse distribution. ...Though uniform diagnostic criteria are unavailable, most of them request typical clinical features and redu …
Small fiber neuropathy (SFN) is a peripheral nervous system disease due to affection of A-delta or C-fibers in a proximal, dis …
Intraepidermal Nerve Fiber Density in Postmortem Skin: A Novel Approach.
Waheed W, Taicher C, Dulaney E, Eckenstein F, Hehir M, Sprague J, Tandan R. Waheed W, et al. J Clin Neuromuscul Dis. 2019 Dec;21(2):69-76. doi: 10.1097/CND.0000000000000264. J Clin Neuromuscul Dis. 2019. PMID: 31743249
OBJECTIVE: To determine the feasibility of examining intraepidermal nerve fiber density (IENFD) in postmortem skin. METHODS: From 12 subjects, 3-mm skin punch biopsies were collected 1-4 days postmortem from the proximal leg and di …
OBJECTIVE: To determine the feasibility of examining intraepidermal nerve fiber density (IENFD) in postmortem …
A Clinician's Approach to Peripheral Neuropathy.
Siao P, Kaku M. Siao P, et al. Semin Neurol. 2019 Oct;39(5):519-530. doi: 10.1055/s-0039-1694747. Epub 2019 Oct 22. Semin Neurol. 2019. PMID: 31639835 Review.
Early categorization of the type of neuropathy can help focus the workup for peripheral neuropathy. Nerve conduction studies and electromyography (NCS/EMG) is the primary diagnostic tool in the evaluation of patients with large-fiber polyneuropathy. ...Laboratory wo …
Early categorization of the type of neuropathy can help focus the workup for peripheral neuropathy. Nerve conduction studies and elec …
Neuromuscular pathology.
Amato AA, De Girolami U. Amato AA, et al. Handb Clin Neurol. 2023;195:287-300. doi: 10.1016/B978-0-323-98818-6.00005-4. Handb Clin Neurol. 2023. PMID: 37562873 Review.
In this chapter, we discuss the indications for muscle, nerve, and skin biopsies, the techniques and normal processing of biopsy specimens, normal histological appearance, and the commonest histopathological abnormalities of different myopathies and ne …
In this chapter, we discuss the indications for muscle, nerve, and skin biopsies, the techniques and normal processing …
Diabetic Peripheral Neuropathy.
Bodman MA, Dreyer MA, Varacallo MA. Bodman MA, et al. 2024 Feb 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2024 Feb 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 28723038 Free Books & Documents.
Neurology consultation and specialized testing, including nerve conduction studies and intraepidermal nerve fiber density testing, are only indicated for patients with atypical clinical features (eg, rapid symptom onset, severe neuromotor impair …
Neurology consultation and specialized testing, including nerve conduction studies and intraepidermal nerve fiber …
Small Fiber Neuropathy.
Zhou L. Zhou L. Semin Neurol. 2019 Oct;39(5):570-577. doi: 10.1055/s-0039-1688977. Epub 2019 Oct 22. Semin Neurol. 2019. PMID: 31639840 Review.
The majority of the patients with SFN suffer from painful paresthesia which can negatively impact their quality of life. Skin biopsy with intraepidermal nerve fiber density evaluation is the gold standard diagnostic test. ...This article …
The majority of the patients with SFN suffer from painful paresthesia which can negatively impact their quality of life. Skin biop …
Cutaneous α-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease.
Gibbons C, Wang N, Rajan S, Kern D, Palma JA, Kaufmann H, Freeman R. Gibbons C, et al. Neurology. 2023 Apr 11;100(15):e1529-e1539. doi: 10.1212/WNL.0000000000206772. Epub 2023 Jan 19. Neurology. 2023. PMID: 36657992 Free PMC article.
All participants underwent neurologic examinations, autonomic testing, and skin biopsies at 3 locations. The density of intraepidermal, sudomotor, and pilomotor nerve fibers was measured. ...Results were compared with clinical rating asse …
All participants underwent neurologic examinations, autonomic testing, and skin biopsies at 3 locations. The density of …
Small Fiber Neuropathy.
Saperstein DS. Saperstein DS. Neurol Clin. 2020 Aug;38(3):607-618. doi: 10.1016/j.ncl.2020.04.001. Neurol Clin. 2020. PMID: 32703472 Review.
Small fiber neuropathy has a broad array of presentations. Length-dependent symptoms and findings present little diagnostic difficulty, but non-length-dependent or multifocal symptoms can be challenging. Intraepidermal nerve fiber density (IENFD …
Small fiber neuropathy has a broad array of presentations. Length-dependent symptoms and findings present little diagnostic difficult …
578 results