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2,580 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Inhaled isoflurane via the anaesthetic conserving device versus propofol for sedation of invasively ventilated patients in intensive care units in Germany and Slovenia: an open-label, phase 3, randomised controlled, non-inferiority trial.
Meiser A, Volk T, Wallenborn J, Guenther U, Becher T, Bracht H, Schwarzkopf K, Knafelj R, Faltlhauser A, Thal SC, Soukup J, Kellner P, Drüner M, Vogelsang H, Bellgardt M, Sackey P; Sedaconda study group. Meiser A, et al. Lancet Respir Med. 2021 Nov;9(11):1231-1240. doi: 10.1016/S2213-2600(21)00323-4. Epub 2021 Aug 26. Lancet Respir Med. 2021. PMID: 34454654 Clinical Trial.
BACKGROUND: Previous studies indicate that isoflurane could be useful for the sedation of patients in the intensive care unit (ICU), but prospective studies evaluating isoflurane's efficacy have been small. ...INTERPRETATION: These results support the use of isof
BACKGROUND: Previous studies indicate that isoflurane could be useful for the sedation of patients in the intensive care unit (ICU), …
Isoflurane promotes early spontaneous breathing in ventilated intensive care patients: A post hoc subgroup analysis of a randomized trial.
Müller-Wirtz LM, Behne F, Kermad A, Wagenpfeil G, Schroeder M, Sessler DI, Volk T, Meiser A. Müller-Wirtz LM, et al. Acta Anaesthesiol Scand. 2022 Mar;66(3):354-364. doi: 10.1111/aas.14010. Epub 2021 Dec 14. Acta Anaesthesiol Scand. 2022. PMID: 34870852 Clinical Trial.
METHODS: We included a single-center subgroup of 66 patients, who participated in a large multi-center trial assessing efficacy and safety of isoflurane sedation, with 33 patients each randomized to isoflurane or propofol sedation. ...RESULTS: Baseline characteristi …
METHODS: We included a single-center subgroup of 66 patients, who participated in a large multi-center trial assessing efficacy and safety o …
Comparison of recovery profile after ambulatory anesthesia with propofol, isoflurane, sevoflurane and desflurane: a systematic review.
Gupta A, Stierer T, Zuckerman R, Sakima N, Parker SD, Fleisher LA. Gupta A, et al. Anesth Analg. 2004 Mar;98(3):632-41, table of contents. doi: 10.1213/01.ane.0000103187.70627.57. Anesth Analg. 2004. PMID: 14980911 Review.
No differences were found between propofol and isoflurane in early recovery. However, early recovery was faster with desflurane compared with propofol and isoflurane and with sevoflurane compared with isoflurane. A minor difference was found in home readiness …
No differences were found between propofol and isoflurane in early recovery. However, early recovery was faster with desflurane compa …
Isoflurane minimum alveolar concentration sparing effects of fentanyl in the dog.
Williamson EJ, Soares JHN, Pavlisko ND, McAlister Council-Troche R, Henao-Guerrero N. Williamson EJ, et al. Vet Anaesth Analg. 2017 Jul;44(4):738-745. doi: 10.1016/j.vaa.2017.02.002. Epub 2017 Feb 22. Vet Anaesth Analg. 2017. PMID: 28701288 Clinical Trial.
OBJECTIVE: To characterize the isoflurane-sparing effects of a high and a low dose of fentanyl in dogs, and its effects on mean arterial pressure (MAP) and heart rate (HR). ...METHODS: Dogs were anesthetized using isoflurane and minimum alveolar concentration (MAC) …
OBJECTIVE: To characterize the isoflurane-sparing effects of a high and a low dose of fentanyl in dogs, and its effects on mean arter …
Isoflurane minimum alveolar concentration reduction by fentanyl.
McEwan AI, Smith C, Dyar O, Goodman D, Smith LR, Glass PS. McEwan AI, et al. Anesthesiology. 1993 May;78(5):864-9. doi: 10.1097/00000542-199305000-00009. Anesthesiology. 1993. PMID: 8489058 Clinical Trial.
BACKGROUND: Isoflurane is commonly combined with fentanyl during anesthesia. Because of hysteresis between plasma and effect site, bolus administration of fentanyl does not accurately describe the interaction between these drugs. ...CONCLUSIONS: Defining the MAC reduction …
BACKGROUND: Isoflurane is commonly combined with fentanyl during anesthesia. Because of hysteresis between plasma and effect site, bo …
Isoflurane produces marked and nonlinear decreases in the vasoconstriction and shivering thresholds.
Xiong J, Kurz A, Sessler DI, Plattner O, Christensen R, Dechert M, Ikeda T. Xiong J, et al. Anesthesiology. 1996 Aug;85(2):240-5. doi: 10.1097/00000542-199608000-00003. Anesthesiology. 1996. PMID: 8712437 Clinical Trial.
Therefore, the hypothesis that isoflurane produces a nonlinear reduction in the vasoconstriction threshold was tested. Because the effect of isoflurane on shivering remains unknown, the extent to which isoflurane reduces the shivering threshold also was deter …
Therefore, the hypothesis that isoflurane produces a nonlinear reduction in the vasoconstriction threshold was tested. Because the ef …
Pharmacokinetics of isoflurane: uptake in the body.
Lu CC, Ho ST, Wong CS, Wang JJ, Tsai CS, Hu OY, Chang SY, Lin CY. Lu CC, et al. Pharmacology. 2003 Nov;69(3):132-7. doi: 10.1159/000072665. Pharmacology. 2003. PMID: 14512699 Clinical Trial.
We investigated the effect of the inspired isoflurane concentration (C(I)iso) on body uptake by comparing the isoflurane concentration in the pulmonary artery blood (PAiso) and that in the arterial blood (Aiso) in 16 patients undergoing coronary artery bypass grafti …
We investigated the effect of the inspired isoflurane concentration (C(I)iso) on body uptake by comparing the isoflurane conce …
Isoflurane alone versus small dose propofol with isoflurane for removal of laryngeal mask airway in children-a randomized controlled trial.
Kumar D, Afshan G, Zubair M, Hamid M. Kumar D, et al. J Pak Med Assoc. 2019 Nov;69(11):1596-1600. doi: 10.5455/JPMA.296240.. J Pak Med Assoc. 2019. PMID: 31740862 Clinical Trial.
The laryngeal mask airway was removed in the intervention group-I at 0.4 minimum alveolar concentration of isoflurane with propofol 1mg/kg. In the control group-II, it was removed at 1.2 minimum alveolar concentration of isoflurane alone. ...CONCLUSIONS: Laryngeal m …
The laryngeal mask airway was removed in the intervention group-I at 0.4 minimum alveolar concentration of isoflurane with propofol 1 …
Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety.
Spencer EM, Willatts SM. Spencer EM, et al. Intensive Care Med. 1992;18(7):415-21. doi: 10.1007/BF01694344. Intensive Care Med. 1992. PMID: 1469180 Clinical Trial.
OBJECTIVE: To compare isoflurane with midazolam for prolonged sedation in ventilated patients. DESIGN: Randomised controlled study. ...INTERVENTIONS: Sedation with either 0.1-0.6% isoflurane in an air-oxygen mixture (30 patients) or a continuous infusion of midazola …
OBJECTIVE: To compare isoflurane with midazolam for prolonged sedation in ventilated patients. DESIGN: Randomised controlled study. . …
Fast Tract Anesthesia Using Isoflurane and Propofol During Off-pump Coronary Artery Bypass Graft Surgery.
Ranjan R, Adhikary D, Rahman M, Mandal S, Saha SK, Adhikary AB. Ranjan R, et al. Mymensingh Med J. 2019 Oct;28(4):811-818. Mymensingh Med J. 2019. PMID: 31599245 Clinical Trial.
This study aimed to evaluate myocardial protective effect of isoflurane and propofol as a fast tract anesthesia in off pump coronary artery bypass graft surgery by measuring postoperative cardiac enzyme Troponin-I, and liver enzyme. ...There is no difference in Troponin-I …
This study aimed to evaluate myocardial protective effect of isoflurane and propofol as a fast tract anesthesia in off pump coronary …
2,580 results