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2020 92
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133 results

Find articles referencing SARS-CoV-2 and COVID-19

COVID-19 and PubMed Clinical Queries NCBI SARS COV-2 literature, sequence, and clinical content
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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, Wang W, Song H, Huang B, Zhu N, Bi Y, Ma X, Zhan F, Wang L, Hu T, Zhou H, Hu Z, Zhou W, Zhao L, Chen J, Meng Y, Wang J, Lin Y, Yuan J, Xie Z, Ma J, Liu WJ, Wang D, Xu W, Holmes EC, Gao GF, Wu G, Chen W, Shi W, Tan W. Lu R, et al. Lancet. 2020 Feb 22;395(10224):565-574. doi: 10.1016/S0140-6736(20)30251-8. Epub 2020 Jan 30. Lancet. 2020. PMID: 32007145 Free PMC article.
Homology modelling was done to explore the likely receptor-binding properties of the virus. FINDINGS: The ten genome sequences of 2019-nCoV obtained from the nine patients were extremely similar, exhibiting more than 9998% sequence identity. ...Phyloge …
Homology modelling was done to explore the likely receptor-binding properties of the virus. FINDINGS: The ten genome sequences …
Virological assessment of hospitalized patients with COVID-2019.
Wölfel R, Corman VM, Guggemos W, Seilmaier M, Zange S, Müller MA, Niemeyer D, Jones TC, Vollmar P, Rothe C, Hoelscher M, Bleicker T, Brünink S, Schneider J, Ehmann R, Zwirglmaier K, Drosten C, Wendtner C. Wölfel R, et al. Nature. 2020 May;581(7809):465-469. doi: 10.1038/s41586-020-2196-x. Epub 2020 Apr 1. Nature. 2020. PMID: 32235945
Infectious virus was readily isolated from samples derived from the throat or lung, but not from stool samples-in spite of high concentrations of virus RNA. ...We consistently detected sequence-distinct virus populations in throat …
Infectious virus was readily isolated from samples derived from the throat or lung, but not from stool samples-i …
The SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT) to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission in low risk, non-severe COVID-19 patients in the first 48 hours after symptoms onset: A structured summary of a study protocol for a randomized control pilot trial.
Chaccour C, Ruiz-Castillo P, Richardson MA, Moncunill G, Casellas A, Carmona-Torre F, Giráldez M, Mota JS, Yuste JR, Azanza JR, Fernández M, Reina G, Dobaño C, Brew J, Sadaba B, Hammann F, Rabinovich R. Chaccour C, et al. Trials. 2020 Jun 8;21(1):498. doi: 10.1186/s13063-020-04421-z. Trials. 2020. PMID: 32513289 Free PMC article.
PARTICIPANTS: The population for the study will be patients with a positive nasopharyngeal swab PCR test for SARS-CoV-2, with non-severe COVID-19 disease, and no risk factors for progression to severity. Vulnerable populations such as pre …
PARTICIPANTS: The population for the study will be patients with a positive nasopharyngeal swab PCR test for SARS-CoV- …
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W; China Novel Coronavirus Investigating and Research Team. Zhu N, et al. N Engl J Med. 2020 Feb 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. Epub 2020 Jan 24. N Engl J Med. 2020. PMID: 31978945 Free PMC article.
A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the …
A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients wit …
Virus Isolation from the First Patient with SARS-CoV-2 in Korea.
Park WB, Kwon NJ, Choi SJ, Kang CK, Choe PG, Kim JY, Yun J, Lee GW, Seong MW, Kim NJ, Seo JS, Oh MD. Park WB, et al. J Korean Med Sci. 2020 Feb 24;35(7):e84. doi: 10.3346/jkms.2020.35.e84. J Korean Med Sci. 2020. PMID: 32080990 Free PMC article.
We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell …
We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first labo …
Viral and host factors related to the clinical outcome of COVID-19.
Zhang X, Tan Y, Ling Y, Lu G, Liu F, Yi Z, Jia X, Wu M, Shi B, Xu S, Chen J, Wang W, Chen B, Jiang L, Yu S, Lu J, Wang J, Xu M, Yuan Z, Zhang Q, Zhang X, Zhao G, Wang S, Chen S, Lu H. Zhang X, et al. Nature. 2020 Jul;583(7816):437-440. doi: 10.1038/s41586-020-2355-0. Epub 2020 May 20. Nature. 2020. PMID: 32434211
In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan (Hubei province, China)(1); it soon spread across the worl …
In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the new coronavirus severe acute respiratory syndrom …
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.
Weisblum Y, Schmidt F, Zhang F, DaSilva J, Poston D, Lorenzi JC, Muecksch F, Rutkowska M, Hoffmann HH, Michailidis E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, Luchsinger L, Hillyer CD, Caskey M, Robbiani DF, Rice CM, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Weisblum Y, et al. Elife. 2020 Oct 28;9:e61312. doi: 10.7554/eLife.61312. Elife. 2020. PMID: 33112236 Free PMC article.
The new coronavirus, SARS-CoV-2, which causes the disease COVID-19, has had a serious worldwide impact on human health. ...An analysis of more than 50,000 real-life SARS-CoV-2 genomes isolated from patient …
The new coronavirus, SARS-CoV-2, which causes the disease COVID-19, has had a serious worldwide impact on …
An Update on Molecular Diagnostics for COVID-19.
Islam KU, Iqbal J. Islam KU, et al. Front Cell Infect Microbiol. 2020 Nov 10;10:560616. doi: 10.3389/fcimb.2020.560616. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33244462 Free PMC article. Review.
A novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been recently identified as an infectious disease affecting the respiratory system of humans. This disease is caused by SARS-C …
A novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) disease (COVID-19) …
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.
To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY. To KK, et al. Lancet Infect Dis. 2020 May;20(5):565-574. doi: 10.1016/S1473-3099(20)30196-1. Epub 2020 Mar 23. Lancet Infect Dis. 2020. PMID: 32213337 Free PMC article.
BACKGROUND: Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial outbreaks. Comprehensive data for serial respiratory viral load and serum antibody responses from patients infected with severe acute respiratory syndrome coronavirus 2 …
BACKGROUND: Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial outbreaks. Comprehensive data for seria …
Identification of Coronavirus Isolated from a Patient in Korea with COVID-19.
Kim JM, Chung YS, Jo HJ, Lee NJ, Kim MS, Woo SH, Park S, Kim JW, Kim HM, Han MG. Kim JM, et al. Osong Public Health Res Perspect. 2020 Feb;11(1):3-7. doi: 10.24171/j.phrp.2020.11.1.02. Osong Public Health Res Perspect. 2020. PMID: 32149036 Free PMC article.
Full genome sequencing showed that the virus genome exhibited sequence homology of more than 99.9% with SARS-CoV-2 which was isolated from patients from other countries, for instance China. Sequence homology of SAR …
Full genome sequencing showed that the virus genome exhibited sequence homology of more than 99.9% with SARS- …
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