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Year Number of Results
1991 1
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2012 5
2013 2
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78 results

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Page 1
Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial.
Kazemi A, Noorbala AA, Azam K, Eskandari MH, Djafarian K. Kazemi A, et al. Clin Nutr. 2019 Apr;38(2):522-528. doi: 10.1016/j.clnu.2018.04.010. Epub 2018 Apr 24. Clin Nutr. 2019. PMID: 29731182 Clinical Trial.
From baseline to 8 weeks, probiotic supplementation resulted in a significant decrease in BDI score (17.39-9.1) compared to the placebo (18.18-15.55) and prebiotic (19.72-14.14) supplementation (p = 0.042). ...However, the kynurenine/tryptophan ratio decreased signi …
From baseline to 8 weeks, probiotic supplementation resulted in a significant decrease in BDI score (17.39-9.1) compared to the place …
Anti-sarcopenic effect of leucine-enriched branched-chain amino acid supplementation among elderly chronic kidney disease patients: a double-blinded randomized controlled trial.
Sunsandee N, Thimachai P, Satirapoj B, Supasyndh O. Sunsandee N, et al. Int Urol Nephrol. 2025 Nov;57(11):3811-3819. doi: 10.1007/s11255-025-04560-9. Epub 2025 May 17. Int Urol Nephrol. 2025. PMID: 40381110 Clinical Trial.
METHODS: A randomized controlled trial was conducted among CKD patients aged over 65 years. The participants were randomly assigned to receive either oral mixed BCAA supplementation (60% leucine, 4.5 g/day; 20% valine, 1.5 g/day; 20% isoleucine, …
METHODS: A randomized controlled trial was conducted among CKD patients aged over 65 years. The participants were rando …
The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial.
Robbins RN, Cortes T, O'Connor JC, Jiwani R, Serra MC. Robbins RN, et al. JMIR Res Protoc. 2023 Nov 1;12:e52199. doi: 10.2196/52199. JMIR Res Protoc. 2023. PMID: 37910166 Free PMC article.
In addition, participants will consume daily either 100 mg/kg body weight of BCAA (2:1:1 leucine:isoleucine:valine) or placebo (maltodextrin) throughout the 8-week intervention. BCAA and placebo powders will be identical in color and dissolved in 400 mL of water and 2.5 g …
In addition, participants will consume daily either 100 mg/kg body weight of BCAA (2:1:1 leucine:isoleucine:valine) or placebo (malto …
Branched-Chain Amino Acid Supplementation Enhances Substrate Metabolism, Exercise Efficiency and Reduces Post-Exercise Fatigue in Active Young Males.
Luan C, Wang Y, Li J, Zhou N, Song G, Ni Z, Xu C, Tang C, Fu P, Wang X, Gong L, Zhang E. Luan C, et al. Nutrients. 2025 Apr 7;17(7):1290. doi: 10.3390/nu17071290. Nutrients. 2025. PMID: 40219047 Free PMC article. Clinical Trial.
Background: Branched-chain amino acids (BCAAs, isoleucine, leucine, and valine) are commonly applied to promote muscle protein synthesis. ...Conclusions: This study shows the critical role of BCAAs during exercise in active males and finds that BCAA supplementation …
Background: Branched-chain amino acids (BCAAs, isoleucine, leucine, and valine) are commonly applied to promote muscle protein synthe …
Branched-Chain Amino Acids Combined with Exercise Improves Physical Function and Quality of Life in Older Adults: Results from a Pilot Randomized Controlled Trial.
Robbins R, O'Connor JC, Cortes TM, Serra MC. Robbins R, et al. Dietetics (Basel). 2025 Sep;4(3):32. doi: 10.3390/dietetics4030032. Epub 2025 Aug 1. Dietetics (Basel). 2025. PMID: 40860958 Free PMC article.
This pilot, randomized, double-blind, placebo-controlled trial investigated the effects of branched-chain amino acids (BCAAs)-provided in a 2:1:1 ratio of leucine:isoleucine: valine-combined with exercise on fatigue, physical performance, and quality of life in older adult …
This pilot, randomized, double-blind, placebo-controlled trial investigated the effects of branched-chain amino acids (BCAAs)-provided in a …
Supplementation With Bacillus clausii UBBC-07 Enhances Circulating Essential Amino Acids in Young Adults: A Double-Blind, Randomized, Controlled Trial.
Tarik M, Ramakrishnan L, Bhatia N, Roy A, Kandasamy D, Chandran DS, Singh A, Kalaivani M, Neelamraju J, Madempudi RS. Tarik M, et al. Cureus. 2025 Mar 24;17(3):e81119. doi: 10.7759/cureus.81119. eCollection 2025 Mar. Cureus. 2025. PMID: 40276429 Free PMC article.
This study aimed to assess the impact of Bacillus clausii(Shouchella clausii) UBBC-07 plus whey protein supplementation on the bioavailability of circulating essential amino acids (EAAs) in physically active young adults. Methods In this double-blind, randomized, …
This study aimed to assess the impact of Bacillus clausii(Shouchella clausii) UBBC-07 plus whey protein supplementation on the bioava …
Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial.
Randolph AC, Markofski MM, Rasmussen BB, Volpi E. Randolph AC, et al. Clin Nutr. 2020 May;39(5):1371-1378. doi: 10.1016/j.clnu.2019.06.017. Epub 2019 Jun 28. Clin Nutr. 2020. PMID: 31307843 Free PMC article. Clinical Trial.
However, excess EAA intake may worsen insulin sensitivity. Here we report the effects of EAA supplementation (EAA, n = 11), placebo (PLA, n = 10), aerobic exercise with placebo (Ex + PLA, n = 11) or Ex with EAA supplementation (Ex + EAA, n = 10) for 22 weeks on insu …
However, excess EAA intake may worsen insulin sensitivity. Here we report the effects of EAA supplementation (EAA, n = 11), placebo ( …
Metabolic effects of keto acid--amino acid supplementation in patients with chronic renal insufficiency receiving a low-protein diet and recombinant human erythropoietin--a randomized controlled trial.
Teplan V, Schück O, Votruba M, Poledne R, Kazdová L, Skibová J, Malý J. Teplan V, et al. Wien Klin Wochenschr. 2001 Sep 17;113(17-18):661-9. Wien Klin Wochenschr. 2001. PMID: 11603100 Clinical Trial.
In a prospective randomized controlled trial over a period of 12 months, we evaluated a total of 38 patients (20 M/18 F) aged 32-68 years with a creatinine clearance (CCr) of 20-36 ml/min. ...In Group I, there was a significant rise in the levels of leucine ( …
In a prospective randomized controlled trial over a period of 12 months, we evaluated a total of 38 patients (20 M/18 F …
Hydrolyzed collagen supplementation prior to resistance exercise augments collagen synthesis in a dose-response manner in resistance-trained, middle-aged men.
Nulty CD, Tang JCY, Dutton J, Dunn R, Fraser WD, Enright K, Stewart CE, Erskine RM. Nulty CD, et al. Am J Physiol Endocrinol Metab. 2024 Nov 1;327(5):E668-E677. doi: 10.1152/ajpendo.00252.2024. Epub 2024 Sep 11. Am J Physiol Endocrinol Metab. 2024. PMID: 39259166 Free article. Clinical Trial.
The AUCs for glycine, proline, hydroxyproline, alanine, arginine, lysine, serine, leucine, valine, and isoleucine were greater with 30 g than 15 g and 0 g HC ingestion (P < 0.05) and greater with 15 g than 0 g HC ingestion (P < 0.05). ...
The AUCs for glycine, proline, hydroxyproline, alanine, arginine, lysine, serine, leucine, valine, and isoleucine were greater with 3 …
Dileucine-supplemented essential amino acids support whole-body anabolism after resistance exercise and serum-stimulated cell-based anabolism.
Aguilera JA, Tinline-Goodfellow CT, Lees MJ, Kortebi I, West DWD, Abou Sawan S, Sharma M, Bashir R, Barnes TM, Ulanov AV, Burd NA, Moore DR. Aguilera JA, et al. J Int Soc Sports Nutr. 2025 Dec 31;22(1):2590090. doi: 10.1080/15502783.2025.2590090. Epub 2025 Nov 30. J Int Soc Sports Nutr. 2025. PMID: 41321015 Free PMC article. Clinical Trial.
Therefore, we aimed to determine the effect of a dileucine-containing essential amino acid formula (DIEAA; 2 g dileucine, 1 g leucine, 9.15 g total EAA) on the anabolic and catabolic responses following resistance exercise in young recreationally active adults when compared with …
Therefore, we aimed to determine the effect of a dileucine-containing essential amino acid formula (DIEAA; 2 g dileucine, 1 g leucine, 9.15 …
78 results