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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 3
1983 7
1984 2
1985 3
1986 5
1987 3
1988 2
1989 2
1990 3
1992 9
1993 3
1994 9
1995 1
1996 3
1997 5
1998 4
1999 11
2000 9
2001 8
2002 6
2003 5
2004 6
2005 9
2006 9
2007 7
2008 7
2009 10
2010 8
2011 8
2012 3
2013 10
2014 11
2015 10
2016 4
2017 9
2018 10
2019 11
2020 15
2021 13
2022 21
2023 14
2024 5

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273 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Adverse Events in Isotretinoin Therapy: A Single-Arm Meta-Analysis.
Kapała J, Lewandowska J, Placek W, Owczarczyk-Saczonek A. Kapała J, et al. Int J Environ Res Public Health. 2022 May 26;19(11):6463. doi: 10.3390/ijerph19116463. Int J Environ Res Public Health. 2022. PMID: 35682048 Free PMC article. Review.
Isotretinoin (ISO) is an oral prescription-only retinoid, well known for its acne-treating effect. ...Three databases (PubMed, ClinicalTrials, and Cochrane Library) were searched using the following terms: "isotretinoin acne vulgaris" for published studies in Englis
Isotretinoin (ISO) is an oral prescription-only retinoid, well known for its acne-treating effect. ...Three databases (PubMed, Clinic
Isotretinoin treatment for acne and risk of depression: A systematic review and meta-analysis.
Huang YC, Cheng YC. Huang YC, et al. J Am Acad Dermatol. 2017 Jun;76(6):1068-1076.e9. doi: 10.1016/j.jaad.2016.12.028. Epub 2017 Mar 11. J Am Acad Dermatol. 2017. PMID: 28291553 Review.
BACKGROUND: The relationship between isotretinoin treatment for acne and depression is controversial. Quantitative analysis has not yet been conducted. ...The prevalence of depression after isotretinoin treatment significantly declined (relative risk [RR] 0.588, 95% …
BACKGROUND: The relationship between isotretinoin treatment for acne and depression is controversial. Quantitative analysis has not y …
Oral isotretinoin for acne.
Costa CS, Bagatin E, Martimbianco ALC, da Silva EM, Lúcio MM, Magin P, Riera R. Costa CS, et al. Cochrane Database Syst Rev. 2018 Nov 24;11(11):CD009435. doi: 10.1002/14651858.CD009435.pub2. Cochrane Database Syst Rev. 2018. PMID: 30484286 Free PMC article.
In addition, different doses, regimens, or formulations of oral isotretinoin were assessed, as well as oral isotretinoin with the addition of topical agents.Pharmaceutical companies funded 12 included trials. ...Only one serious adverse event was reported in the …
In addition, different doses, regimens, or formulations of oral isotretinoin were assessed, as well as oral isotretinoin with …
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma.
Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM; Children's Oncology Group. Yu AL, et al. N Engl J Med. 2010 Sep 30;363(14):1324-34. doi: 10.1056/NEJMoa0911123. N Engl J Med. 2010. PMID: 20879881 Free PMC article. Clinical Trial.
We conducted a study to determine whether adding ch14.18, GM-CSF, and interleukin-2 to standard isotretinoin therapy after intensive multimodal therapy would improve outcomes in high-risk neuroblastoma. METHODS: Patients with high-risk neuroblastoma who had a response to i …
We conducted a study to determine whether adding ch14.18, GM-CSF, and interleukin-2 to standard isotretinoin therapy after intensive …
Low-dose oral isotretinoin for the treatment of adult patients with mild-to-moderate acne vulgaris: Systematic review and meta-analysis.
Al Muqarrab F, Almohssen A. Al Muqarrab F, et al. Dermatol Ther. 2022 Apr;35(4):e15311. doi: 10.1111/dth.15311. Epub 2022 Jan 31. Dermatol Ther. 2022. PMID: 35000295 Review.
Acne vulgaris is one of the most common dermatologic complaints. Recently, isotretinoin has been used as an off-label indication for the treatment of mild-to-moderate grades of acne not responding to conventional treatment. ...To qualify the state of evidence and analyze t …
Acne vulgaris is one of the most common dermatologic complaints. Recently, isotretinoin has been used as an off-label indication for …
Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children's Oncology Group.
Leary SES, Packer RJ, Li Y, Billups CA, Smith KS, Jaju A, Heier L, Burger P, Walsh K, Han Y, Embry L, Hadley J, Kumar R, Michalski J, Hwang E, Gajjar A, Pollack IF, Fouladi M, Northcott PA, Olson JM. Leary SES, et al. JAMA Oncol. 2021 Sep 1;7(9):1313-1321. doi: 10.1001/jamaoncol.2021.2224. JAMA Oncol. 2021. PMID: 34292305 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate therapy intensification with carboplatin as a radiosensitizer and isotretinoin as a proapoptotic agent in children with high-risk medulloblastoma in a randomized clinical trial and, with a correlative biology study, facilitate planned subgroup analys …
OBJECTIVE: To evaluate therapy intensification with carboplatin as a radiosensitizer and isotretinoin as a proapoptotic agent in chil …
Use of isotretinoin and risk of depression in patients with acne: a systematic review and meta-analysis.
Li C, Chen J, Wang W, Ai M, Zhang Q, Kuang L. Li C, et al. BMJ Open. 2019 Jan 21;9(1):e021549. doi: 10.1136/bmjopen-2018-021549. BMJ Open. 2019. PMID: 30670500 Free PMC article.
PARTICIPANTS: Patients with acne. INTERVENTIONS: Studies comparing isotretinoin with other interventions in patients with acne were included. ...CONCLUSIONS: This study suggested an association of the use of isotretinoin in patients with acne with significantly impr …
PARTICIPANTS: Patients with acne. INTERVENTIONS: Studies comparing isotretinoin with other interventions in patients with acne were i …
Isotretinoin Exposure and Risk of Inflammatory Bowel Disease: A Systematic Review with Meta-Analysis and Trial Sequential Analysis.
Yu CL, Chou PY, Liang CS, Chiang LH, Wang TY, Tu YK, Chi CC. Yu CL, et al. Am J Clin Dermatol. 2023 Sep;24(5):721-730. doi: 10.1007/s40257-023-00765-9. Epub 2023 Apr 3. Am J Clin Dermatol. 2023. PMID: 37010780
BACKGROUND: Cases of inflammatory bowel disease (IBD) following isotretinoin use have been reported previously, but whether isotretinoin exposure is associated with IBD has been unclear. ...CONCLUSION: This meta-analysis with TSA found no evidence of an association …
BACKGROUND: Cases of inflammatory bowel disease (IBD) following isotretinoin use have been reported previously, but whether isotre
A systematic review and network meta-analysis of topical pharmacological, oral pharmacological, physical and combined treatments for acne vulgaris.
Mavranezouli I, Daly CH, Welton NJ, Deshpande S, Berg L, Bromham N, Arnold S, Phillippo DM, Wilcock J, Xu J, Ravenscroft JC, Wood D, Rafiq M, Fou L, Dworzynski K, Healy E. Mavranezouli I, et al. Br J Dermatol. 2022 Nov;187(5):639-649. doi: 10.1111/bjd.21739. Epub 2022 Aug 22. Br J Dermatol. 2022. PMID: 35789996 Free PMC article. Review.
Topical pharmacological treatment combinations, oral antibiotics combined with topical pharmacological treatments, oral isotretinoin and photodynamic therapy were most effective for moderate-to-severe acne. ...For moderate-to-severe acne, topical treatment combinations, or …
Topical pharmacological treatment combinations, oral antibiotics combined with topical pharmacological treatments, oral isotretinoin
Ocular side effects of systemic isotretinoin - a systematic review and summary of case reports.
Lamberg O, Strome A, Jones F, Mleczek J, Jarocki A, Troost JP, Helfrich Y. Lamberg O, et al. J Dermatolog Treat. 2023 Dec;34(1):2213364. doi: 10.1080/09546634.2023.2213364. J Dermatolog Treat. 2023. PMID: 37248700 Free article.
Background: Isotretinoin is frequently used for treatment of severe nodulocystic and papulopustular acne, however use is limited by mucocutaneous, ocular, and systemic side effects.Objective: (1) provide a systematic meta-analysis of ocular side effects during isotretin
Background: Isotretinoin is frequently used for treatment of severe nodulocystic and papulopustular acne, however use is limited by m …
273 results