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Page 1
Postural Orthostatic Tachycardia Syndrome: Mechanisms and New Therapies.
Mar PL, Raj SR. Mar PL, et al. Annu Rev Med. 2020 Jan 27;71:235-248. doi: 10.1146/annurev-med-041818-011630. Epub 2019 Aug 14. Annu Rev Med. 2020. PMID: 31412221 Review.
Postural orthostatic tachycardia syndrome (POTS) is a clinically heterogeneous disorder with multiple contributing pathophysiologic mechanisms manifesting as symptoms of orthostatic intolerance in the setting of orthostatic tachycardia (increase in heart rate …
Postural orthostatic tachycardia syndrome (POTS) is a clinically heterogeneous disorder with multiple contributing pathophysio …
Ivabradine in Postural Orthostatic Tachycardia Syndrome: A Review of the Literature.
Tahir F, Bin Arif T, Majid Z, Ahmed J, Khalid M. Tahir F, et al. Cureus. 2020 Apr 28;12(4):e7868. doi: 10.7759/cureus.7868. Cureus. 2020. PMID: 32489723 Free PMC article. Review.
Postural orthostatic tachycardia syndrome (POTS) is an autonomic disorder characterized by symptoms such as palpitations, dyspnea, chest discomfort, and lightheadedness affecting various systems. ...This review aims to provide a comprehensive and up-to-date picture …
Postural orthostatic tachycardia syndrome (POTS) is an autonomic disorder characterized by symptoms such as palpitations, dysp …
Randomized Trial of Ivabradine in Patients With Hyperadrenergic Postural Orthostatic Tachycardia Syndrome.
Taub PR, Zadourian A, Lo HC, Ormiston CK, Golshan S, Hsu JC. Taub PR, et al. J Am Coll Cardiol. 2021 Feb 23;77(7):861-871. doi: 10.1016/j.jacc.2020.12.029. J Am Coll Cardiol. 2021. PMID: 33602468 Free article. Clinical Trial.
BACKGROUND: Postural orthostatic tachycardia syndrome (POTS) is a complex, multifaceted disorder that impairs functional status and quality of life. ...There was a strong trend in reduction of NE levels upon standing with ivabradine (p = 0.056). Patients did …
BACKGROUND: Postural orthostatic tachycardia syndrome (POTS) is a complex, multifaceted disorder that impairs functional statu …
Ivabradine as a Treatment for Postural Orthostatic Tachycardia Syndrome: A Systematic Review.
Kwok CS, Gillespie D, Ur Rehman Qazi N, Nazari B, Hall M, Lip GYH, Loke YK, Qureshi AI, Holroyd E, Raj SR. Kwok CS, et al. J Cardiovasc Pharmacol. 2026 Jun 1;87(6):438-445. doi: 10.1097/FJC.0000000000001784. J Cardiovasc Pharmacol. 2026. PMID: 41364925
Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). ...The exact role of ivabradine in treatment of POTS needs to be clarified in further randomized trials and more robust evidence....
Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). . …
The evidence for treatments for postural orthostatic tachycardia syndrome: a systematic review of randomized trials.
Kwok CS, Lee S, Hall M, Qureshi AI, Lip GYH, Loke YK, Raj SR, Holroyd E. Kwok CS, et al. Trends Cardiovasc Med. 2025 Nov;35(8):517-527. doi: 10.1016/j.tcm.2025.07.001. Epub 2025 Jul 11. Trends Cardiovasc Med. 2025. PMID: 40653179
Postural orthostatic tachycardia syndrome (POTS) is defined as the presence of chronic symptoms of orthostatic intolerance accompanied by an increase in heart rate greater than 30 beats per minute within 10 min of assuming an upright posture in the absences o …
Postural orthostatic tachycardia syndrome (POTS) is defined as the presence of chronic symptoms of orthostatic intolerance acc …
Ivabradine for the Treatment of Postural Orthostatic Tachycardia Syndrome: A Systematic Review.
Gee ME, Watkins AK, Brown JN, Young EJA. Gee ME, et al. Am J Cardiovasc Drugs. 2018 Jun;18(3):195-204. doi: 10.1007/s40256-017-0252-1. Am J Cardiovasc Drugs. 2018. PMID: 29330767
OBJECTIVE: The objective of this systematic review is to evaluate the evidence for the efficacy and safety of ivabradine for the treatment of POTS. METHODS: MEDLINE (from 1956 to August 2017) and EMBASE (from 1957 to August 2017) were queried with the following search term …
OBJECTIVE: The objective of this systematic review is to evaluate the evidence for the efficacy and safety of ivabradine for the trea …
Use of Ivabradine in the Treatment of Patients with Postural Orthostatic Tachycardia Syndrome (POTS): A Systematic Review.
Melo APG, Moretti MA, Chagas ACP. Melo APG, et al. Arq Bras Cardiol. 2025 Nov;122(11):e20250347. doi: 10.36660/abc.20250347. Arq Bras Cardiol. 2025. PMID: 41538594 Free PMC article. English, Portuguese.
OBJECTIVES: To evaluate the efficacy and safety of ivabradine in the treatment of POTS. METHOD: Systematic review using the descriptors "Ivabradine" and "Postural Orthostatic Tachycardia Syndrome" in the PubMed, Scielo, LILACS, and Google Scholar datab …
OBJECTIVES: To evaluate the efficacy and safety of ivabradine in the treatment of POTS. METHOD: Systematic review using the descripto …
Postural Tachycardia Syndrome and COVID-19: Focus on Ivabradine Therapy.
Dixit K, Frishman WH. Dixit K, et al. Cardiol Rev. 2024 May-Jun 01;32(3):279-284. doi: 10.1097/CRD.0000000000000503. Epub 2022 Dec 5. Cardiol Rev. 2024. PMID: 36729924
In this article we discuss the association of postural orthostatic tachycardia syndrome (POTS) with coronavirus-19 (COVID-19), ivabradine's unique mechanism of action, and its use in POTS patients. ...The initial management strategy for POTS is largely …
In this article we discuss the association of postural orthostatic tachycardia syndrome (POTS) with coronavirus-19 (COVID-19), …
Dysautonomia: a common comorbidity of systemic disease.
Blitshteyn S. Blitshteyn S. Immunol Res. 2025 Jul 8;73(1):105. doi: 10.1007/s12026-025-09661-2. Immunol Res. 2025. PMID: 40624434 Free PMC article. Review.
The most common autonomic disorders encountered in clinical practice are postural orthostatic tachycardia syndrome (POTS), neurocardiogenic syncope (NCS), and orthostatic hypotension (OH), which may be undiagnosed or often mislabeled with psychiatric disorders. ...T …
The most common autonomic disorders encountered in clinical practice are postural orthostatic tachycardia syndrome (POTS), neu …
Ivabradine effects on COVID-19-associated postural orthostatic tachycardia syndrome: a single center prospective study.
Abdelnabi M, Saleh Y, Ahmed A, Benjanuwattra J, Leelaviwat N, Almaghraby A. Abdelnabi M, et al. Am J Cardiovasc Dis. 2023 Jun 25;13(3):162-167. eCollection 2023. Am J Cardiovasc Dis. 2023. PMID: 37469536 Free PMC article.
The main pathophysiology can be attributed to dysautonomia or autonomic nervous system dysfunction. Postural orthostatic tachycardia syndrome (POTS) is a complex, multisystemic disorder affecting usually younger age with tachycardia at rest or with minimal ef …
The main pathophysiology can be attributed to dysautonomia or autonomic nervous system dysfunction. Postural orthostatic tachycard …
80 results