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378 results

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Ivermectin as an inhibitor of cancer stem-like cells.
Dominguez-Gomez G, Chavez-Blanco A, Medina-Franco JL, Saldivar-Gonzalez F, Flores-Torrontegui Y, Juarez M, Díaz-Chávez J, Gonzalez-Fierro A, Dueñas-González A. Dominguez-Gomez G, et al. Mol Med Rep. 2018 Feb;17(2):3397-3403. doi: 10.3892/mmr.2017.8231. Epub 2017 Dec 8. Mol Med Rep. 2018. PMID: 29257278
The aim of the present study was to demonstrate that ivermectin preferentially inhibited cancer stem-like cells (CSC) in breast cancer cells and downregulated the expression of 'stemness' genes. ...Ivermectin exhibited a similarity value of 0.78 in ref …
The aim of the present study was to demonstrate that ivermectin preferentially inhibited cancer stem-like cells (CSC) in breas …
Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth.
Zhou S, Wu H, Ning W, Wu X, Xu X, Ma Y, Li X, Hu J, Wang C, Wang J. Zhou S, et al. Front Pharmacol. 2021 Aug 13;12:717529. doi: 10.3389/fphar.2021.717529. eCollection 2021. Front Pharmacol. 2021. PMID: 34483925 Free PMC article.
Colorectal cancer (CRC) is the third most common cancer worldwide and still lacks effective therapy. ...Overall, ivermectin suppressed cell proliferation by promoting ROS-mediated mitochondrial apoptosis pathway and inducing S phase arrest in CRC cells, sugge …
Colorectal cancer (CRC) is the third most common cancer worldwide and still lacks effective therapy. ...Overall, ivermectin …
Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer.
Lv S, Wu Z, Luo M, Zhang Y, Zhang J, Pascal LE, Wang Z, Wei Q. Lv S, et al. Cell Death Dis. 2022 Sep 1;13(9):754. doi: 10.1038/s41419-022-05182-0. Cell Death Dis. 2022. PMID: 36050295 Free PMC article.
Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. ...Herein, we report the pharmacological effects and targets of ivermectin in prostate cancer. Ivermectin caused G0/G1 cell cycle arr …
Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. ...Herein, we …
Ivermectin and gemcitabine combination treatment induces apoptosis of pancreatic cancer cells via mitochondrial dysfunction.
Lee DE, Kang HW, Kim SY, Kim MJ, Jeong JW, Hong WC, Fang S, Kim HS, Lee YS, Kim HJ, Park JS. Lee DE, et al. Front Pharmacol. 2022 Aug 26;13:934746. doi: 10.3389/fphar.2022.934746. eCollection 2022. Front Pharmacol. 2022. PMID: 36091811 Free PMC article.
Ivermectin, an antiparasitic drug, exerts antitumor effects in various cancer types. This is the first study to evaluate the anticancer effects of the combination of ivermectin and gemcitabine in pancreatic cancer. ...These results indicate that ive …
Ivermectin, an antiparasitic drug, exerts antitumor effects in various cancer types. This is the first study to evaluate the a …
Antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug.
Juarez M, Schcolnik-Cabrera A, Dominguez-Gomez G, Chavez-Blanco A, Diaz-Chavez J, Duenas-Gonzalez A. Juarez M, et al. Cancer Chemother Pharmacol. 2020 Jun;85(6):1153-1163. doi: 10.1007/s00280-020-04041-z. Epub 2020 May 30. Cancer Chemother Pharmacol. 2020. PMID: 32474842
PURPOSE: Ivermectin is an antiparasitic drug that exhibits antitumor effects in preclinical studies, and as such is currently being repositioned for cancer treatment. ...Conversely, the prostate cancer cell line DU145 was the most resistant to its use. In the …
PURPOSE: Ivermectin is an antiparasitic drug that exhibits antitumor effects in preclinical studies, and as such is currently being r …
Ivermectin Inhibits Bladder Cancer Cell Growth and Induces Oxidative Stress and DNA Damage.
Fan N, Zhang L, Wang Z, Ding H, Yue Z. Fan N, et al. Anticancer Agents Med Chem. 2024;24(5):348-357. doi: 10.2174/0118715206274095231106042833. Anticancer Agents Med Chem. 2024. PMID: 38375808
Xenograft tumor models in nude mice were used to investigate the anti-cancer effect of Ivermectin in vivo. RESULTS: Our study showed that in vitro and in vivo, Ivermectin inhibited the growth of bladder cancer cells. ...CONCLUSIONS: According to these …
Xenograft tumor models in nude mice were used to investigate the anti-cancer effect of Ivermectin in vivo. RESULTS: Our study …
Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-kappaB pathway.
Jiang L, Wang P, Sun YJ, Wu YJ. Jiang L, et al. J Exp Clin Cancer Res. 2019 Jun 18;38(1):265. doi: 10.1186/s13046-019-1251-7. J Exp Clin Cancer Res. 2019. PMID: 31215501 Free PMC article.
In this study, we sought to explore whether ivermectin (IVM), a macrolide antiparasitic agent, could overcome the resistance of cancer cells to the therapeutic drugs. ...Thus, ivermectin, a FDA-approved antiparasitic drug, could potentially be used in combina …
In this study, we sought to explore whether ivermectin (IVM), a macrolide antiparasitic agent, could overcome the resistance of ca …
Ivermectin, a potential anticancer drug derived from an antiparasitic drug.
Tang M, Hu X, Wang Y, Yao X, Zhang W, Yu C, Cheng F, Li J, Fang Q. Tang M, et al. Pharmacol Res. 2021 Jan;163:105207. doi: 10.1016/j.phrs.2020.105207. Epub 2020 Sep 21. Pharmacol Res. 2021. PMID: 32971268 Free PMC article.
Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of ivermectin against parasitic diseases. Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signal …
Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of ivermectin against parasit …
Doxycycline, salinomycin, monensin and ivermectin repositioned as cancer drugs.
Markowska A, Kaysiewicz J, Markowska J, Huczyński A. Markowska A, et al. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1549-1554. doi: 10.1016/j.bmcl.2019.04.045. Epub 2019 Apr 27. Bioorg Med Chem Lett. 2019. PMID: 31054863 Review.
Noteworthy, in recent years discoveries of novel anticancer agents from well-known antibiotics have opened up new treatment pathways for several cancer diseases. The aim of this review article is to describe new applications for the following antibiotics: doxycycline (DOX) …
Noteworthy, in recent years discoveries of novel anticancer agents from well-known antibiotics have opened up new treatment pathways for sev …
Outcome of Ivermectin in Cancer Treatment: An Experience in Loja-Ecuador.
Jiménez-Gaona Y, Vivanco-Galván O, Morales-Larreategui G, Cabrera-Bejarano A, Lakshminarayanan V. Jiménez-Gaona Y, et al. Nurs Rep. 2023 Feb 22;13(1):315-326. doi: 10.3390/nursrep13010030. Nurs Rep. 2023. PMID: 36976682 Free PMC article.
(1) Background: Cancer is one of the leading causes of death worldwide, and trends in cancer incidence and mortality are increasing over last years in Loja-Ecuador. ...One such alternative treatment is ivermectin-based antiparasitic, which is commonly used in …
(1) Background: Cancer is one of the leading causes of death worldwide, and trends in cancer incidence and mortality are incre …
378 results

Searches related to "ivermectin cancer"