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2005 2
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2016 4
2017 5
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2019 9
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2022 2
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Page 1
Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy.
Hutchings AJ, Hambrecht B, Veh A, Giridhar NJ, Zare A, Angerer C, Ohnesorge T, Schenke M, Selvaraj BT, Chandran S, Sterneckert J, Petri S, Seeger B, Briese M, Stigloher C, Bischler T, Hermann A, Damme M, Sendtner M, Lüningschrör P. Hutchings AJ, et al. Among authors: sterneckert j. Nat Commun. 2024 Oct 4;15(1):8622. doi: 10.1038/s41467-024-52875-5. Nat Commun. 2024. PMID: 39366938 Free PMC article.
Glycolic acid and D-lactate-putative products of DJ-1-restore neurodegeneration in FUS - and SOD1-ALS.
Pal A, Grossmann D, Glaß H, Zimyanin V, Günther R, Catinozzi M, Boeckers TM, Sterneckert J, Storkebaum E, Petri S, Wegner F, Grill SW, Pan-Montojo F, Hermann A. Pal A, et al. Among authors: sterneckert j. Life Sci Alliance. 2024 May 17;7(8):e202302535. doi: 10.26508/lsa.202302535. Print 2024 Aug. Life Sci Alliance. 2024. PMID: 38760174 Free PMC article.
Targeting low levels of MIF expression as a potential therapeutic strategy for ALS.
Alfahel L, Gschwendtberger T, Kozareva V, Dumas L, Gibbs R, Kertser A, Baruch K, Zaccai S, Kahn J, Thau-Habermann N, Eggenschwiler R, Sterneckert J, Hermann A, Sundararaman N, Vaibhav V, Van Eyk JE, Rafuse VF, Fraenkel E, Cantz T, Petri S, Israelson A. Alfahel L, et al. Among authors: sterneckert j. Cell Rep Med. 2024 May 21;5(5):101546. doi: 10.1016/j.xcrm.2024.101546. Epub 2024 May 3. Cell Rep Med. 2024. PMID: 38703766 Free PMC article.
Axonal Lysosomal Assays for Characterizing the Effects of LRRK2 G2019S.
Bhatia P, Bickle M, Agrawal AA, Truss B, Nikolaidi A, Brockmann K, Reinhardt L, Vogel S, Szegoe EM, Pal A, Hermann A, Mikicic I, Yun M, Falkenburger B, Sterneckert J. Bhatia P, et al. Among authors: sterneckert j. Biology (Basel). 2024 Jan 20;13(1):58. doi: 10.3390/biology13010058. Biology (Basel). 2024. PMID: 38275734 Free PMC article.
Drosha-dependent microRNAs modulate FUS-mediated neurodegeneration in vivo.
Kour S, Fortuna T, Anderson EN, Mawrie D, Bilstein J, Sivasubramanian R, Ward C, Roy R, Rajasundaram D, Sterneckert J, Pandey UB. Kour S, et al. Among authors: sterneckert j. Nucleic Acids Res. 2023 Nov 10;51(20):11258-11276. doi: 10.1093/nar/gkad774. Nucleic Acids Res. 2023. PMID: 37791873 Free PMC article.
Base editing: a promising tool to rescue spinal muscular atrophy.
Bhatia P, Sterneckert J. Bhatia P, et al. Among authors: sterneckert j. Signal Transduct Target Ther. 2023 Sep 25;8(1):362. doi: 10.1038/s41392-023-01583-5. Signal Transduct Target Ther. 2023. PMID: 37743375 Free PMC article. No abstract available.
Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in FUS ALS Motoneurons.
Zimyanin VL, Pielka AM, Glaß H, Japtok J, Großmann D, Martin M, Deussen A, Szewczyk B, Deppmann C, Zunder E, Andersen PM, Boeckers TM, Sterneckert J, Redemann S, Storch A, Hermann A. Zimyanin VL, et al. Among authors: sterneckert j. Cells. 2023 May 9;12(10):1352. doi: 10.3390/cells12101352. Cells. 2023. PMID: 37408187 Free PMC article.
A 3D cell culture system for bioengineering human neuromuscular junctions to model ALS.
Massih B, Veh A, Schenke M, Mungwa S, Seeger B, Selvaraj BT, Chandran S, Reinhardt P, Sterneckert J, Hermann A, Sendtner M, Lüningschrör P. Massih B, et al. Among authors: sterneckert j. Front Cell Dev Biol. 2023 Feb 14;11:996952. doi: 10.3389/fcell.2023.996952. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36866276 Free PMC article.
Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS.
Günther R, Pal A, Williams C, Zimyanin VL, Liehr M, von Neubeck C, Krause M, Parab MG, Petri S, Kalmbach N, Marklund SL, Sterneckert J, Munch Andersen P, Wegner F, Gilthorpe JD, Hermann A. Günther R, et al. Among authors: sterneckert j. Cells. 2022 Apr 6;11(7):1246. doi: 10.3390/cells11071246. Cells. 2022. PMID: 35406813 Free PMC article.
Structural binding site comparisons reveal Crizotinib as a novel LRRK2 inhibitor.
Bolz SN, Salentin S, Jennings G, Haupt VJ, Sterneckert J, Schroeder M. Bolz SN, et al. Among authors: sterneckert j. Comput Struct Biotechnol J. 2021 Jun 10;19:3674-3681. doi: 10.1016/j.csbj.2021.06.013. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34285770 Free PMC article.
Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling.
Mediani L, Antoniani F, Galli V, Vinet J, Carrà AD, Bigi I, Tripathy V, Tiago T, Cimino M, Leo G, Amen T, Kaganovich D, Cereda C, Pansarasa O, Mandrioli J, Tripathi P, Troost D, Aronica E, Buchner J, Goswami A, Sterneckert J, Alberti S, Carra S. Mediani L, et al. Among authors: sterneckert j. EMBO Rep. 2021 May 5;22(5):e51740. doi: 10.15252/embr.202051740. Epub 2021 Mar 19. EMBO Rep. 2021. PMID: 33738926 Free PMC article.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: sterneckert j. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
Concomitant gain and loss of function pathomechanisms in C9ORF72 amyotrophic lateral sclerosis.
Pal A, Kretner B, Abo-Rady M, Glaβ H, Dash BP, Naumann M, Japtok J, Kreiter N, Dhingra A, Heutink P, Böckers TM, Günther R, Sterneckert J, Hermann A. Pal A, et al. Among authors: sterneckert j. Life Sci Alliance. 2021 Feb 22;4(4):e202000764. doi: 10.26508/lsa.202000764. Print 2021 Apr. Life Sci Alliance. 2021. PMID: 33619157 Free PMC article.
Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins.
Abo-Rady M, Kalmbach N, Pal A, Schludi C, Janosch A, Richter T, Freitag P, Bickle M, Kahlert AK, Petri S, Stefanov S, Glass H, Staege S, Just W, Bhatnagar R, Edbauer D, Hermann A, Wegner F, Sterneckert JL. Abo-Rady M, et al. Among authors: sterneckert jl. Stem Cell Reports. 2020 Mar 10;14(3):390-405. doi: 10.1016/j.stemcr.2020.01.010. Epub 2020 Feb 20. Stem Cell Reports. 2020. PMID: 32084385 Free PMC article.
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization.
Casci I, Krishnamurthy K, Kour S, Tripathy V, Ramesh N, Anderson EN, Marrone L, Grant RA, Oliver S, Gochenaur L, Patel K, Sterneckert J, Gleixner AM, Donnelly CJ, Ruepp MD, Sini AM, Zuccaro E, Pennuto M, Pasinelli P, Pandey UB. Casci I, et al. Among authors: sterneckert j. Nat Commun. 2019 Dec 6;10(1):5583. doi: 10.1038/s41467-019-13383-z. Nat Commun. 2019. PMID: 31811140 Free PMC article.
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
Kremer L, Hennes E, Brause A, Ursu A, Robke L, Matsubayashi HT, Nihongaki Y, Flegel J, Mejdrová I, Eickhoff J, Baumann M, Nencka R, Janning P, Kordes S, Schöler HR, Sterneckert J, Inoue T, Ziegler S, Waldmann H. Kremer L, et al. Among authors: sterneckert j. Angew Chem Int Ed Engl. 2019 Nov 11;58(46):16617-16628. doi: 10.1002/anie.201907632. Epub 2019 Oct 4. Angew Chem Int Ed Engl. 2019. PMID: 31454140 Free PMC article. Review.
Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F, Kalmbach N, Naujock M, Staege S, Eggenschwiler R, Abo-Rady M, Japtok J, Guo W, Hensel N, Reinhardt P, Boeckers TM, Cantz T, Sterneckert J, Van Den Bosch L, Hermann A, Petri S, Wegner F. Bursch F, et al. Among authors: sterneckert j. Hum Mol Genet. 2019 Sep 1;28(17):2835-2850. doi: 10.1093/hmg/ddz107. Hum Mol Genet. 2019. PMID: 31108504
Modeling Parkinson's disease in midbrain-like organoids.
Smits LM, Reinhardt L, Reinhardt P, Glatza M, Monzel AS, Stanslowsky N, Rosato-Siri MD, Zanon A, Antony PM, Bellmann J, Nicklas SM, Hemmer K, Qing X, Berger E, Kalmbach N, Ehrlich M, Bolognin S, Hicks AA, Wegner F, Sterneckert JL, Schwamborn JC. Smits LM, et al. Among authors: sterneckert jl. NPJ Parkinsons Dis. 2019 Apr 5;5:5. doi: 10.1038/s41531-019-0078-4. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 30963107 Free PMC article.
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy.
Marrone L, Drexler HCA, Wang J, Tripathi P, Distler T, Heisterkamp P, Anderson EN, Kour S, Moraiti A, Maharana S, Bhatnagar R, Belgard TG, Tripathy V, Kalmbach N, Hosseinzadeh Z, Crippa V, Abo-Rady M, Wegner F, Poletti A, Troost D, Aronica E, Busskamp V, Weis J, Pandey UB, Hyman AA, Alberti S, Goswami A, Sterneckert J. Marrone L, et al. Among authors: sterneckert j. Acta Neuropathol. 2019 Jul;138(1):67-84. doi: 10.1007/s00401-019-01998-x. Epub 2019 Apr 1. Acta Neuropathol. 2019. PMID: 30937520 Free PMC article.
Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo.
Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, Menninger S, Zischinsky G, Eickhoff J, Fröb C, Bhattarai P, Arulmozhivarman G, Marrone L, Janosch A, Adachi K, Stehling M, Anderson EN, Abo-Rady M, Bickle M, Pandey UB, Reimer MM, Kizil C, Schöler HR, Nussbaumer P, Klebl B, Sterneckert JL. Reinhardt L, et al. Among authors: sterneckert jl. Stem Cell Reports. 2019 Mar 5;12(3):502-517. doi: 10.1016/j.stemcr.2019.01.015. Epub 2019 Feb 14. Stem Cell Reports. 2019. PMID: 30773488 Free PMC article.
RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Maharana S, Wang J, Papadopoulos DK, Richter D, Pozniakovsky A, Poser I, Bickle M, Rizk S, Guillén-Boixet J, Franzmann TM, Jahnel M, Marrone L, Chang YT, Sterneckert J, Tomancak P, Hyman AA, Alberti S. Maharana S, et al. Among authors: sterneckert j. Science. 2018 May 25;360(6391):918-921. doi: 10.1126/science.aar7366. Epub 2018 Apr 12. Science. 2018. PMID: 29650702 Free PMC article.
Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease.
Marrone L, Bus C, Schöndorf D, Fitzgerald JC, Kübler M, Schmid B, Reinhardt P, Reinhardt L, Deleidi M, Levin T, Meixner A, Klink B, Glatza M, Gloeckner CJ, Gasser T, Sterneckert J. Marrone L, et al. Among authors: sterneckert j. PLoS One. 2018 Mar 7;13(3):e0192497. doi: 10.1371/journal.pone.0192497. eCollection 2018. PLoS One. 2018. PMID: 29513666 Free PMC article.
Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein.
Höing S, Yeh TY, Baumann M, Martinez NE, Habenberger P, Kremer L, Drexler HCA, Küchler P, Reinhardt P, Choidas A, Zischinsky ML, Zischinsky G, Nandini S, Ledray AP, Ketcham SA, Reinhardt L, Abo-Rady M, Glatza M, King SJ, Nussbaumer P, Ziegler S, Klebl B, Schroer TA, Schöler HR, Waldmann H, Sterneckert J. Höing S, et al. Among authors: sterneckert j. Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6. doi: 10.1016/j.chembiol.2017.12.014. Epub 2018 Jan 27. Cell Chem Biol. 2018. PMID: 29396292 Free PMC article.
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt JH, Holzmann K, Troost D, Ludolph AC, Boeckers TM, Liebau S, Petri S, Cordes N, Hyman AA, Wegner F, Grill SW, Weis J, Storch A, Hermann A. Naumann M, et al. Among authors: sterneckert j. Nat Commun. 2018 Jan 23;9(1):335. doi: 10.1038/s41467-017-02299-1. Nat Commun. 2018. PMID: 29362359 Free PMC article.
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL. Marrone L, et al. Among authors: sterneckert jl. Stem Cell Reports. 2018 Feb 13;10(2):375-389. doi: 10.1016/j.stemcr.2017.12.018. Epub 2018 Jan 18. Stem Cell Reports. 2018. PMID: 29358088 Free PMC article.
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, Ordovás L, Patel A, Welters M, Vanwelden T, Geens N, Tricot T, Benoy V, Steyaert J, Lefebvre-Omar C, Boesmans W, Jarpe M, Sterneckert J, Wegner F, Petri S, Bohl D, Vanden Berghe P, Robberecht W, Van Damme P, Verfaillie C, Van Den Bosch L. Guo W, et al. Among authors: sterneckert j. Nat Commun. 2017 Oct 11;8(1):861. doi: 10.1038/s41467-017-00911-y. Nat Commun. 2017. PMID: 29021520 Free PMC article.
Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction.
Kremer L, Schultz-Fademrecht C, Baumann M, Habenberger P, Choidas A, Klebl B, Kordes S, Schöler HR, Sterneckert J, Ziegler S, Schneider G, Waldmann H. Kremer L, et al. Among authors: sterneckert j. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13021-13025. doi: 10.1002/anie.201707394. Epub 2017 Sep 18. Angew Chem Int Ed Engl. 2017. PMID: 28833911
Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors.
Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann AL, Cui QL, Schambach A, Kim KP, Bachelin C, Marteyn A, Hargus G, Johnson RM, Antel J, Sterneckert J, Zaehres H, Schöler HR, Baron-Van Evercooren A, Kuhlmann T. Ehrlich M, et al. Among authors: sterneckert j. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2243-E2252. doi: 10.1073/pnas.1614412114. Epub 2017 Feb 28. Proc Natl Acad Sci U S A. 2017. PMID: 28246330 Free PMC article.
Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization.
Stanslowsky N, Reinhardt P, Glass H, Kalmbach N, Naujock M, Hensel N, Lübben V, Pal A, Venneri A, Lupo F, De Franceschi L, Claus P, Sterneckert J, Storch A, Hermann A, Wegner F. Stanslowsky N, et al. Among authors: sterneckert j. J Neurosci. 2016 Nov 23;36(47):12027-12043. doi: 10.1523/JNEUROSCI.0456-16.2016. J Neurosci. 2016. PMID: 27881786 Free PMC article.
C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.
Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, Lojewski X, Sterneckert J, Hermann A, Shaw PJ, Ince PG, Mann M, Meissner F, Sendtner M. Sivadasan R, et al. Among authors: sterneckert j. Nat Neurosci. 2016 Dec;19(12):1610-1618. doi: 10.1038/nn.4407. Epub 2016 Oct 10. Nat Neurosci. 2016. PMID: 27723745 Free article.
4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.
Naujock M, Stanslowsky N, Bufler S, Naumann M, Reinhardt P, Sterneckert J, Kefalakes E, Kassebaum C, Bursch F, Lojewski X, Storch A, Frickenhaus M, Boeckers TM, Putz S, Demestre M, Liebau S, Klingenstein M, Ludolph AC, Dengler R, Kim KS, Hermann A, Wegner F, Petri S. Naujock M, et al. Among authors: sterneckert j. Stem Cells. 2016 Jun;34(6):1563-75. doi: 10.1002/stem.2354. Epub 2016 Mar 28. Stem Cells. 2016. PMID: 26946488
Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein.
Ehrlich M, Hallmann AL, Reinhardt P, Araúzo-Bravo MJ, Korr S, Röpke A, Psathaki OE, Ehling P, Meuth SG, Oblak AL, Murrell JR, Ghetti B, Zaehres H, Schöler HR, Sterneckert J, Kuhlmann T, Hargus G. Ehrlich M, et al. Among authors: sterneckert j. Stem Cell Reports. 2015 Jul 14;5(1):83-96. doi: 10.1016/j.stemcr.2015.06.001. Epub 2015 Jul 2. Stem Cell Reports. 2015. PMID: 26143746 Free PMC article.
Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain.
Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H. Hargus G, et al. Among authors: sterneckert j. Cell Rep. 2014 Sep 25;8(6):1697-1703. doi: 10.1016/j.celrep.2014.08.014. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220454 Free article.
iPS cell derived neuronal cells for drug discovery.
Heilker R, Traub S, Reinhardt P, Schöler HR, Sterneckert J. Heilker R, et al. Among authors: sterneckert j. Trends Pharmacol Sci. 2014 Oct;35(10):510-9. doi: 10.1016/j.tips.2014.07.003. Epub 2014 Aug 3. Trends Pharmacol Sci. 2014. PMID: 25096281 Review.
Investigating human disease using stem cell models.
Sterneckert JL, Reinhardt P, Schöler HR. Sterneckert JL, et al. Nat Rev Genet. 2014 Sep;15(9):625-39. doi: 10.1038/nrg3764. Epub 2014 Jul 29. Nat Rev Genet. 2014. PMID: 25069490 Review.
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.
Lojewski X, Staropoli JF, Biswas-Legrand S, Simas AM, Haliw L, Selig MK, Coppel SH, Goss KA, Petcherski A, Chandrachud U, Sheridan SD, Lucente D, Sims KB, Gusella JF, Sondhi D, Crystal RG, Reinhardt P, Sterneckert J, Schöler H, Haggarty SJ, Storch A, Hermann A, Cotman SL. Lojewski X, et al. Among authors: sterneckert j. Hum Mol Genet. 2014 Apr 15;23(8):2005-22. doi: 10.1093/hmg/ddt596. Epub 2013 Nov 23. Hum Mol Genet. 2014. PMID: 24271013 Free PMC article.
Discovery of neuritogenic compound classes inspired by natural products.
Dakas PY, Parga JA, Höing S, Schöler HR, Sterneckert J, Kumar K, Waldmann H. Dakas PY, et al. Among authors: sterneckert j. Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9576-81. doi: 10.1002/anie.201302045. Epub 2013 Jun 3. Angew Chem Int Ed Engl. 2013. PMID: 23733315 No abstract available.
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. Among authors: sterneckert j. PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. PLoS One. 2013. PMID: 23533608 Free PMC article.
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.
Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. Among authors: sterneckert j. Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008. Cell Stem Cell. 2013. PMID: 23472874 Free article.
Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay.
Höing S, Rudhard Y, Reinhardt P, Glatza M, Stehling M, Wu G, Peiker C, Böcker A, Parga JA, Bunk E, Schwamborn JC, Slack M, Sterneckert J, Schöler HR. Höing S, et al. Among authors: sterneckert j. Cell Stem Cell. 2012 Nov 2;11(5):620-32. doi: 10.1016/j.stem.2012.07.005. Epub 2012 Oct 11. Cell Stem Cell. 2012. PMID: 23064101 Free article.
Zfp296 is a novel, pluripotent-specific reprogramming factor.
Fischedick G, Klein DC, Wu G, Esch D, Höing S, Han DW, Reinhardt P, Hergarten K, Tapia N, Schöler HR, Sterneckert JL. Fischedick G, et al. Among authors: sterneckert jl. PLoS One. 2012;7(4):e34645. doi: 10.1371/journal.pone.0034645. Epub 2012 Apr 2. PLoS One. 2012. PMID: 22485183 Free PMC article.
Neural induction intermediates exhibit distinct roles of Fgf signaling.
Sterneckert J, Stehling M, Bernemann C, Araúzo-Bravo MJ, Greber B, Gentile L, Ortmeier C, Sinn M, Wu G, Ruau D, Zenke M, Brintrup R, Klein DC, Ko K, Schöler HR. Sterneckert J, et al. Stem Cells. 2010 Oct;28(10):1772-81. doi: 10.1002/stem.498. Stem Cells. 2010. PMID: 20715182