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Year Number of Results
1991 1
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1995 2
1996 2
1997 1
1998 1
1999 1
2000 2
2002 1
2003 1
2004 2
2006 3
2007 4
2008 5
2009 1
2010 9
2011 9
2012 7
2013 4
2014 5
2015 7
2016 7
2017 5
2018 7
2019 8
2020 9
2021 10
2022 4
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102 results
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Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan).
Li Y, Lin W, Huang J, Xie Y, Ma W. Li Y, et al. Chin Med. 2016 Sep 27;11:43. doi: 10.1186/s13020-016-0114-9. eCollection 2016. Chin Med. 2016. PMID: 27708693 Free PMC article. Review.
Gynostemma pentaphyllum (Thunb.) Makino (GpM) (Jiaogulan) has been widely used in Chinese medicine for the treatment of several diseases, including hepatitis, diabetes and cardiovascular disease. Furthermore, GpM has recently been shown to exhibit potent anti-can …
Gynostemma pentaphyllum (Thunb.) Makino (GpM) (Jiaogulan) has been widely used in Chinese medicine for the treatment of severa …
Mushroom polysaccharides and jiaogulan saponins exert cancer preventive effects by shaping the gut microbiota and microenvironment in ApcMin/+ mice.
Khan I, Huang G, Li XA, Liao W, Leong WK, Xia W, Bian X, Wu J, Hsiao WLW. Khan I, et al. Pharmacol Res. 2019 Oct;148:104448. doi: 10.1016/j.phrs.2019.104448. Epub 2019 Sep 6. Pharmacol Res. 2019. PMID: 31499195
The incidence of colorectal cancer (CRC) is alarming among younger peoples. While no effective chemopreventive drug available in the market, researchers have been searching for alternative strategies against CRC that are in demand. Therefore, we tested the cancer-pr …
The incidence of colorectal cancer (CRC) is alarming among younger peoples. While no effective chemopreventive drug available in the …
Prebiotic properties of jiaogulan in the context of gut microbiome.
Huang G, Yasir M, Zheng Y, Khan I. Huang G, et al. Food Sci Nutr. 2022 Jan 22;10(3):731-739. doi: 10.1002/fsn3.2701. eCollection 2022 Mar. Food Sci Nutr. 2022. PMID: 35282005 Free PMC article. Review.
Jiaogulan (Gynostemma pentaphyllum) is a traditional Chinese medicinal herb that has been widely used in food and supplemental products. ...More recently, there has been growing interest in the prebiotic potential of jiaogulan, especially at the interface of …
Jiaogulan (Gynostemma pentaphyllum) is a traditional Chinese medicinal herb that has been widely used in food and supplemental …
Triterpenoids from the genus Gynostemma: Chemistry and pharmacological activities.
Nguyen NH, Ha TKQ, Yang JL, Pham HTT, Oh WK. Nguyen NH, et al. J Ethnopharmacol. 2021 Mar 25;268:113574. doi: 10.1016/j.jep.2020.113574. Epub 2020 Nov 10. J Ethnopharmacol. 2021. PMID: 33186700 Review.
MATERIALS AND METHODS: The relevant literature on the genus Gynostemma was gathered from secondary databases (Web of Science and PubMed), books, and official websites. ...However, the promising preliminary data of other Gynostemma species indicated the research pote …
MATERIALS AND METHODS: The relevant literature on the genus Gynostemma was gathered from secondary databases (Web of Science and PubM …
Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum).
Wang J, Yang JL, Zhou PP, Meng XH, Shi YP. Wang J, et al. J Agric Food Chem. 2017 Jul 26;65(29):5926-5934. doi: 10.1021/acs.jafc.7b01477. Epub 2017 Jul 11. J Agric Food Chem. 2017. PMID: 28662582
Jiaogulan (Gynostemma pentaphyllum) has been widely used as a herbal tea, dietary supplement, and vegetable in Asian countries. ...Gypenoside 5 was found to possess protein tyrosine phosphatase 1B inhibitory activity, with an IC(50) value of 8.2 0.9 muM, and moderat …
Jiaogulan (Gynostemma pentaphyllum) has been widely used as a herbal tea, dietary supplement, and vegetable in Asian countries …
Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum.
Liao W, Khan I, Huang G, Chen S, Liu L, Leong WK, Li XA, Wu J, Wendy Hsiao WL. Liao W, et al. Gut Microbes. 2021 Jan-Dec;13(1):1847629. doi: 10.1080/19490976.2020.1847629. Epub 2020 Nov 24. Gut Microbes. 2021. PMID: 33228450 Free PMC article.
Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. ...Hence, keeping a balanced gut microbiota (GM) has become a novel pursue in the medical field, particularly in the area of gastrointestinal disorders. Gynostemma pentaphy …
Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. ...Hence, keeping a balanced gut microb …
Gypenoside LI arrests the cell cycle of breast cancer in G0/G1 phase by down-regulating E2F1.
Zu ML, Duan Y, Xie JB, Qi YS, Xie P, Borjigidai A, Piao XL. Zu ML, et al. J Ethnopharmacol. 2021 Jun 12;273:114017. doi: 10.1016/j.jep.2021.114017. Epub 2021 Mar 11. J Ethnopharmacol. 2021. PMID: 33716078
Previous studies have shown that gypnenoside LI possess inhibitory effect on the growth of many cancer cells. However, its pharmacological effect in breast cancer and the mechanism have not been reported yet. ...It could be used as potential multi-target chemopreven …
Previous studies have shown that gypnenoside LI possess inhibitory effect on the growth of many cancer cells. However, its pharmacolo …
Gypenoside L Inhibits Proliferation of Liver and Esophageal Cancer Cells by Inducing Senescence.
Ma J, Hu X, Liao C, Xiao H, Zhu Q, Li Y, Liu Z, Tao A, He Z, Xu C, Zheng K. Ma J, et al. Molecules. 2019 Mar 18;24(6):1054. doi: 10.3390/molecules24061054. Molecules. 2019. PMID: 30889805 Free PMC article.
In our study, we investigated the inhibitory effect of gypenoside L (Gyp-L), a saponin isolated from Gynostemma pentaphyllum, on cancer cell growth. We found that Gyp-L increased the SA-beta-galactosidase activity, promoted the production of senescence-associated se …
In our study, we investigated the inhibitory effect of gypenoside L (Gyp-L), a saponin isolated from Gynostemma pentaphyllum, on c …
Progress in the Medicinal Value, Bioactive Compounds, and Pharmacological Activities of Gynostemma pentaphyllum.
Su C, Li N, Ren R, Wang Y, Su X, Lu F, Zong R, Yang L, Ma X. Su C, et al. Molecules. 2021 Oct 15;26(20):6249. doi: 10.3390/molecules26206249. Molecules. 2021. PMID: 34684830 Free PMC article. Review.
Gynostemma pentaphyllum (Thunb.) Makino (GP), also named Jiaogulan in Chinese, was known to people for its function in both health care and disease treatment. ...Both in vivo and in vitro tests, ranging from different cell lines to animals, indicated that GP possess …
Gynostemma pentaphyllum (Thunb.) Makino (GP), also named Jiaogulan in Chinese, was known to people for its function in both he …
102 results