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Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan).
Li Y, Lin W, Huang J, Xie Y, Ma W. Li Y, et al. Chin Med. 2016 Sep 27;11:43. doi: 10.1186/s13020-016-0114-9. eCollection 2016. Chin Med. 2016. PMID: 27708693 Free PMC article. Review.
Gynostemma pentaphyllum (Thunb.) Makino (GpM) (Jiaogulan) has been widely used in Chinese medicine for the treatment of several diseases, including hepatitis, diabetes and cardiovascular disease. Furthermore, GpM has recently been shown to exhibit potent anti-can
Gynostemma pentaphyllum (Thunb.) Makino (GpM) (Jiaogulan) has been widely used in Chinese medicine for the treatment of severa
Prebiotic properties of jiaogulan in the context of gut microbiome.
Huang G, Yasir M, Zheng Y, Khan I. Huang G, et al. Food Sci Nutr. 2022 Jan 22;10(3):731-739. doi: 10.1002/fsn3.2701. eCollection 2022 Mar. Food Sci Nutr. 2022. PMID: 35282005 Free PMC article. Review.
Jiaogulan (Gynostemma pentaphyllum) is a traditional Chinese medicinal herb that has been widely used in food and supplemental products. ...More recently, there has been growing interest in the prebiotic potential of jiaogulan, especially at the interface of
Jiaogulan (Gynostemma pentaphyllum) is a traditional Chinese medicinal herb that has been widely used in food and supplemental
Progress in the Medicinal Value, Bioactive Compounds, and Pharmacological Activities of Gynostemma pentaphyllum.
Su C, Li N, Ren R, Wang Y, Su X, Lu F, Zong R, Yang L, Ma X. Su C, et al. Molecules. 2021 Oct 15;26(20):6249. doi: 10.3390/molecules26206249. Molecules. 2021. PMID: 34684830 Free PMC article. Review.
Gynostemma pentaphyllum (Thunb.) Makino (GP), also named Jiaogulan in Chinese, was known to people for its function in both health care and disease treatment. ...Both in vivo and in vitro tests, ranging from different cell lines to animals, indicated that GP possess
Gynostemma pentaphyllum (Thunb.) Makino (GP), also named Jiaogulan in Chinese, was known to people for its function in both he
Targeted modulation of gut microbiota by traditional Chinese medicine and natural products for liver disease therapy.
Zhu LR, Li SS, Zheng WQ, Ni WJ, Cai M, Liu HP. Zhu LR, et al. Front Immunol. 2023 Feb 2;14:1086078. doi: 10.3389/fimmu.2023.1086078. eCollection 2023. Front Immunol. 2023. PMID: 36817459 Free PMC article. Review.
The gut microbiota not only constitutes intestinal microenvironment homeostasis and human health but also exerts indispensable roles in the occurrence and progression of multiple liver diseases, including alcohol-related liver disease, nonalcoholic fatty liver disease, autoimmune …
The gut microbiota not only constitutes intestinal microenvironment homeostasis and human health but also exerts indispensable roles in the …
Mushroom polysaccharides and jiaogulan saponins exert cancer preventive effects by shaping the gut microbiota and microenvironment in Apc(Min/+) mice.
Khan I, Huang G, Li XA, Liao W, Leong WK, Xia W, Bian X, Wu J, Hsiao WLW. Khan I, et al. Pharmacol Res. 2019 Oct;148:104448. doi: 10.1016/j.phrs.2019.104448. Epub 2019 Sep 6. Pharmacol Res. 2019. PMID: 31499195
The incidence of colorectal cancer (CRC) is alarming among younger peoples. While no effective chemopreventive drug available in the market, researchers have been searching for alternative strategies against CRC that are in demand. Therefore, we tested the cancer-pr …
The incidence of colorectal cancer (CRC) is alarming among younger peoples. While no effective chemopreventive drug available in the …
Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.
Yang PW, Xu PL, Cheng CS, Jiao JY, Wu Y, Dong S, Xie J, Zhu XY. Yang PW, et al. J Ethnopharmacol. 2022 Oct 28;297:115516. doi: 10.1016/j.jep.2022.115516. Epub 2022 Jul 8. J Ethnopharmacol. 2022. PMID: 35817247
ETHNOPHARMACOLOGICAL RELEVANCE: The Qingyihuaji decoction (QYHJ) is composed of seven herbs: Scutellaria barbata D.Don (Banzhilian, HSB), Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan, GP), Oldenlandia diffusa (Willd.) ...The KEGG pathway analysis showed signif …
ETHNOPHARMACOLOGICAL RELEVANCE: The Qingyihuaji decoction (QYHJ) is composed of seven herbs: Scutellaria barbata D.Don (Banzhilian, HSB), …
Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum).
Wang J, Yang JL, Zhou PP, Meng XH, Shi YP. Wang J, et al. J Agric Food Chem. 2017 Jul 26;65(29):5926-5934. doi: 10.1021/acs.jafc.7b01477. Epub 2017 Jul 11. J Agric Food Chem. 2017. PMID: 28662582
Jiaogulan (Gynostemma pentaphyllum) has been widely used as a herbal tea, dietary supplement, and vegetable in Asian countries. ...Gypenoside 5 was found to possess protein tyrosine phosphatase 1B inhibitory activity, with an IC(50) value of 8.2 0.9 muM, and moderat
Jiaogulan (Gynostemma pentaphyllum) has been widely used as a herbal tea, dietary supplement, and vegetable in Asian countries
Gypenoside-Induced Apoptosis via the PI3K/AKT/mTOR Signaling Pathway in Bladder Cancer.
Li X, Liu H, Lv C, Du J, Lian F, Zhang S, Wang Z, Zeng Y. Li X, et al. Biomed Res Int. 2022 Mar 29;2022:9304552. doi: 10.1155/2022/9304552. eCollection 2022. Biomed Res Int. 2022. PMID: 35402614 Free PMC article.
Gypenosides are the major active components of G. pentaphyllum, and they have been widely reported to possess antitumor effects in prostate cancer, gastric cancer, hepatocellular carcinoma, colon cancer, lung cancer, and breast cancer. ...Furthe …
Gypenosides are the major active components of G. pentaphyllum, and they have been widely reported to possess antitumor effects in prostate …
Gypensapogenin I Suppresses Cell Proliferation in Triple-Negative Breast Cancer Via Triggering the Closure of AKT/GSK3beta/beta-Catenin and Notch-1 Signaling Pathways.
Tan H, Li M, Han L, Zhao Y, Zhang X. Tan H, et al. J Agric Food Chem. 2022 May 4;70(17):5438-5449. doi: 10.1021/acs.jafc.2c02512. Epub 2022 Apr 23. J Agric Food Chem. 2022. PMID: 35465659
Jiaogulan (Gynostemma pentaphyllum) tea is a functional food that is commercially available worldwide. ...Therefore, Jiaogulan tea can not only be used as a health food but also possesses the possibility to treat triple-negative breast cancer (TNBC)...
Jiaogulan (Gynostemma pentaphyllum) tea is a functional food that is commercially available worldwide. ...Therefore, Jiaogu
Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum.
Liao W, Khan I, Huang G, Chen S, Liu L, Leong WK, Li XA, Wu J, Wendy Hsiao WL. Liao W, et al. Gut Microbes. 2021 Jan-Dec;13(1):1847629. doi: 10.1080/19490976.2020.1847629. Epub 2020 Nov 24. Gut Microbes. 2021. PMID: 33228450 Free PMC article.
Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. ...Hence, keeping a balanced gut microbiota (GM) has become a novel pursue in the medical field, particularly in the area of gastrointestinal disorders. Gynostemma pentaphy …
Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. ...Hence, keeping a balanced gut microb …
116 results