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Year Number of Results
2014 3
2015 2
2016 3
2017 2
2018 2
2019 2
2020 4
2021 1
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Chemotherapy, host response and molecular dynamics in periampullary cancer: the CHAMP study.
Hau SO, Petersson A, Nodin B, Karnevi E, Boman K, Williamsson C, Eberhard J, Leandersson K, Gisselsson D, Heby M, Jirström K. Hau SO, et al. BMC Cancer. 2020 Apr 15;20(1):308. doi: 10.1186/s12885-020-06807-3. BMC Cancer. 2020. PMID: 32293352 Free PMC article. Clinical Trial.
Therefore, the "Chemotherapy, Host Response and Molecular Dynamics in Periampullary Cancer (CHAMP)" study aims to monitor these processes to gain new insight into this perplexing disease. ...DISCUSSION: Despite the recent emergence of some promising biomarkers for peria
Therefore, the "Chemotherapy, Host Response and Molecular Dynamics in Periampullary Cancer (CHAMP)" study aims to monitor these proce …
Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma.
Lundgren S, Elebro J, Heby M, Nodin B, Leandersson K, Micke P, Jirström K, Mezheyeuski A. Lundgren S, et al. Int J Cancer. 2020 Jun 15;146(12):3461-3473. doi: 10.1002/ijc.32945. Epub 2020 Mar 20. Int J Cancer. 2020. PMID: 32129882 Free article.
Therefore, the aim of our study was to perform a detailed in situ description of lymphocyte infiltration patterns in resected pancreatic and other periampullary cancers. Multiplexed immunofluorescence imaging was applied to tissue microarrays with tumors from a cohort of 1 …
Therefore, the aim of our study was to perform a detailed in situ description of lymphocyte infiltration patterns in resected pancreatic and …
Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma.
Lundgren S, Micke P, Elebro J, Heby M, Hrynchyk I, Nodin B, Leandersson K, Mezheyeuski A, Jirström K. Lundgren S, et al. Front Immunol. 2020 Sep 10;11:558169. doi: 10.3389/fimmu.2020.558169. eCollection 2020. Front Immunol. 2020. PMID: 33013928 Free PMC article.
The aim of this study was to comprehensively map the abundance, topographic distribution and spatial interaction of innate and innate-like immune cells in the tumor microenvironment of periampullary adenocarcinoma. METHODS: Multiplexed immunofluorescent imaging was perform …
The aim of this study was to comprehensively map the abundance, topographic distribution and spatial interaction of innate and innate-like i …
Mutational Landscape in Resected Periampullary Adenocarcinoma: Relationship With Morphology and Clinical Outcome.
Lundgren S, Hau SO, Elebro J, Heby M, Karnevi E, Nodin B, Eberhard J, Holm K, Staaf J, Jönsson GB, Jirström K. Lundgren S, et al. JCO Precis Oncol. 2019 Mar 21;3:PO.18.00323. doi: 10.1200/PO.18.00323. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914025 Free PMC article.
PURPOSE: Periampullary adenocarcinomas encompass a heterogeneous group of tumors with dismal prognosis and limited treatment options. ...CONCLUSION: To our knowledge, this is the first description of the mutational landscape in the full spectrum of periampullary ade …
PURPOSE: Periampullary adenocarcinomas encompass a heterogeneous group of tumors with dismal prognosis and limited treatment options. …
Clinical significance of stromal ER and PR expression in periampullary adenocarcinoma.
Andersson G, Lundgren S, Heby M, Nodin B, Elebro J, Jirström K. Andersson G, et al. Biomark Res. 2019 Nov 19;7:26. doi: 10.1186/s40364-019-0176-9. eCollection 2019. Biomark Res. 2019. PMID: 31827798 Free PMC article.
None of these trials did however include biomarkers, and the relevance of female hormone signaling in pancreatic or other periampullary adenocarcinoma remains largely unexplored. The aim of this study was to examine the extent and potential clinical significance of estroge …
None of these trials did however include biomarkers, and the relevance of female hormone signaling in pancreatic or other periampullary
Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas.
Heby M, Karnevi E, Elebro J, Nodin B, Eberhard J, Saukkonen K, Hagström J, Mustonen H, Seppänen H, Haglund C, Jirström K, Larsson AH. Heby M, et al. Sci Rep. 2020 Jun 25;10(1):10373. doi: 10.1038/s41598-020-67187-z. Sci Rep. 2020. PMID: 32587323 Free PMC article.
The outcome of periampullary adenocarcinomas remains poor with few treatment options. ...A correlation and adverse prognostic synergy between PODXL and the epidermal growth factor receptor (EGFR) has been observed in colorectal cancer. Here, we investigated whether this al …
The outcome of periampullary adenocarcinomas remains poor with few treatment options. ...A correlation and adverse prognostic synergy …
Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer.
Elebro J, Ben Dror L, Heby M, Nodin B, Jirström K, Eberhard J. Elebro J, et al. Acta Oncol. 2016;55(3):286-96. doi: 10.3109/0284186X.2015.1075663. Epub 2015 Sep 11. Acta Oncol. 2016. PMID: 26362587 Free PMC article.
Here, we investigated the prognostic impact of hENT1, dCK and HuR in pancreatobiliary (PB) and intestinal (I) type periampullary cancers, respectively. MATERIAL AND METHODS: Immunohistochemical expression of hENT1, dCK and HuR was evaluated in tissue microarrays with all p …
Here, we investigated the prognostic impact of hENT1, dCK and HuR in pancreatobiliary (PB) and intestinal (I) type periampullary canc …
Relationship between mismatch repair immunophenotype and long-term survival in patients with resected periampullary adenocarcinoma.
Heby M, Lundgren S, Nodin B, Elebro J, Eberhard J, Jirström K. Heby M, et al. J Transl Med. 2018 Mar 14;16(1):66. doi: 10.1186/s12967-018-1444-4. J Transl Med. 2018. PMID: 29540182 Free PMC article.
The clinical significance of deficient mismatch repair (dMMR) in periampullary adenocarcinoma is comparatively unexplored. Herein, we examined the associations of MMR immunophenotype with long-term survival in patients with resected periampullary adenocarcinoma, wit …
The clinical significance of deficient mismatch repair (dMMR) in periampullary adenocarcinoma is comparatively unexplored. Herein, we …
Prognostic and treatment predictive significance of SATB1 and SATB2 expression in pancreatic and periampullary adenocarcinoma.
Elebro J, Heby M, Gaber A, Nodin B, Jonsson L, Fristedt R, Uhlén M, Jirström K, Eberhard J. Elebro J, et al. J Transl Med. 2014 Oct 17;12:289. doi: 10.1186/s12967-014-0289-8. J Transl Med. 2014. PMID: 25323550 Free PMC article.
BACKGROUND: Pancreatic cancer and other pancreaticobiliary type periampullary adenocarcinomas have a dismal prognosis even after resection and neoadjuvant chemotherapy. Intestinal type periampullary adenocarcinomas generally have a better prognosis, but little is kn …
BACKGROUND: Pancreatic cancer and other pancreaticobiliary type periampullary adenocarcinomas have a dismal prognosis even after rese …
Prognostic and predictive significance of podocalyxin-like protein expression in pancreatic and periampullary adenocarcinoma.
Heby M, Elebro J, Nodin B, Jirström K, Eberhard J. Heby M, et al. BMC Clin Pathol. 2015 May 30;15:10. doi: 10.1186/s12907-015-0009-1. eCollection 2015. BMC Clin Pathol. 2015. PMID: 26028992 Free PMC article.
BACKGROUND: Adenocarcinoma of the periampullary region is associated with poor prognosis and new prognostic and treatment predictive biomarkers are needed for improved treatment. ...CONCLUSION: Membranous expression of PODXL is significantly higher in PB-type than in I-typ …
BACKGROUND: Adenocarcinoma of the periampullary region is associated with poor prognosis and new prognostic and treatment predictive …
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