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Page 1
Synthesis and Activity of a Novel Autotaxin Inhibitor-Icodextrin Conjugate.
Fisher N, Edwards MG, Hemming R, Allin SM, Wallis JD, Bulman Page PC, Mckenzie MJ, Jones SM, Elsegood MRJ, King-Underwood J, Richardson A. Fisher N, et al. Among authors: king underwood j. J Med Chem. 2018 Sep 13;61(17):7942-7951. doi: 10.1021/acs.jmedchem.8b00935. Epub 2018 Aug 15. J Med Chem. 2018. PMID: 30059212
Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus.
Fordyce EAF, Brookes DW, Lise-Ciana C, Coates MS, Hunt SF, Ito K, King-Underwood J, Onions ST, Parra GF, Rapeport G, Sherbukhin V, Stockwell JA, Strong P, Thomas JC, Murray J. Fordyce EAF, et al. Among authors: king underwood j. Bioorg Med Chem Lett. 2017 May 15;27(10):2201-2206. doi: 10.1016/j.bmcl.2017.03.053. Epub 2017 Mar 23. Bioorg Med Chem Lett. 2017. PMID: 28372911
Correction: Conformationally restricted benzothienoazepine respiratory syncytial virus inhibitors: their synthesis, structural analysis and biological activities.
Fordyce EAF, Fraser Hunt S, Crepin D, Onions ST, Parra GF, Sleigh CJ, King-Underwood J, Finch H, Murray J. Fordyce EAF, et al. Among authors: king underwood j. Medchemcomm. 2018 Mar 26;9(4):746. doi: 10.1039/c8md90016g. eCollection 2018 Apr 1. Medchemcomm. 2018. PMID: 30288214 Free PMC article.
Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma.
Onions ST, Ito K, Charron CE, Brown RJ, Colucci M, Frickel F, Hardy G, Joly K, King-Underwood J, Kizawa Y, Knowles I, Murray PJ, Novak A, Rani A, Rapeport G, Smith A, Strong P, Taddei DM, Williams JG. Onions ST, et al. Among authors: king underwood j. J Med Chem. 2016 Mar 10;59(5):1727-46. doi: 10.1021/acs.jmedchem.5b01029. Epub 2016 Feb 4. J Med Chem. 2016. PMID: 26800309
In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection.
Colley T, Sehra G, Chowdhary A, Alanio A, Kelly SL, Kizawa Y, Armstrong-James D, Fisher MC, Warrilow AGS, Parker JE, Kelly DE, Kimura G, Nishimoto Y, Sunose M, Onions S, Crepin D, Lagasse F, Crittall M, Shannon J, McConville M, King-Underwood J, Naylor A, Bretagne S, Murray J, Ito K, Strong P, Rapeport G. Colley T, et al. Among authors: king underwood j. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e01941-17. doi: 10.1128/AAC.01941-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29439966 Free PMC article.
In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection.
Colley T, Alanio A, Kelly SL, Sehra G, Kizawa Y, Warrilow AGS, Parker JE, Kelly DE, Kimura G, Anderson-Dring L, Nakaoki T, Sunose M, Onions S, Crepin D, Lagasse F, Crittall M, Shannon J, Cooke M, Bretagne S, King-Underwood J, Murray J, Ito K, Strong P, Rapeport G. Colley T, et al. Among authors: king underwood j. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02280-16. doi: 10.1128/AAC.02280-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28223388 Free PMC article.