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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 5
2004 3
2005 3
2006 1
2007 3
2008 4
2009 4
2010 6
2011 1
2012 4
2013 5
2014 3
2015 5
2016 6
2017 5
2018 6
2019 6
2020 3
2021 5
2022 1
2023 5
2024 3
2025 8
2026 4

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84 results

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Page 1
Venetoclax in combination with cytarabine with or without idarubicin or azacitidine in children, adolescents, and young adults with relapsed or refractory acute myeloid leukaemia (VENAML): a multicentre, phase 1 expansion study.
Daniels KP, Pounds SB, Wu H, Wang L, Alexander TB, Budhraja A, Wolf J, Westover T, Mead PE, Mehr CM, Gupta SD, Lacayo NJ, Inaba H, Rees M, Pui CH, Opferman JT, Klco JM, Rubnitz JE, Karol SE. Daniels KP, et al. Lancet Haematol. 2026 Jul 8:S2352-3026(26)00136-5. doi: 10.1016/S2352-3026(26)00136-5. Online ahead of print. Lancet Haematol. 2026. PMID: 42419338 Free article.
Mitochondrial integrated stress response activation creates a therapeutic vulnerability to MCL-1 inhibition in acute myeloid leukemia.
Brakefield-Laird L, Budhraja A, Hall PM, Brewington D, Moore J, Lott J, Ni Y, Voronin D, Grant-Chapman O, Mukiza TO, Wright T, Wang YD, Radko-Juettner S, Pruett-Miller SM, Pounds S, Vogel P, Opferman JT. Brakefield-Laird L, et al. Cell Death Dis. 2026 Jun 25. doi: 10.1038/s41419-026-09037-w. Online ahead of print. Cell Death Dis. 2026. PMID: 42350371 Free article.
Mitochondrial proteostasis regulated by CRL5Ozz and Alix modulates skeletal muscle metabolism and fiber type.
Campos Y, Palacios G, Gomero E, van de Vlekkert D, Venkataraman K, John J, Weesner JA, Wakefield R, Qiu X, Rodriguez-Enriquez R, Rockfield S, Demmers J, Opferman JT, Robinson C, Khairy K, Bertorini T, Grosveld GC, d'Azzo A. Campos Y, et al. Commun Biol. 2025 Dec 22;9(1):331. doi: 10.1038/s42003-025-09363-3. Commun Biol. 2025. PMID: 41429925 Free PMC article.
Venetoclax plus gilteritinib is effective in preclinical models of FLT3-mutant BCL11B-a lineage-ambiguous leukemia.
Montefiori LE, Iacobucci I, Gao Q, Moore J, Wright WC, Wei H, Baviskar P, Sona S, Jin H, Budhraja A, Lott J, Tatarata QZ, Cheng Z, Khan T, Backhaus Wagner EA, Johnson M, Mehr CM, Freeman B, Janke L, Haferlach T, Geeleher P, Mead PE, Konopleva M, Opferman JT, Mullighan CG. Montefiori LE, et al. Blood. 2025 Nov 6;146(19):2350-2356. doi: 10.1182/blood.2025028985. Blood. 2025. PMID: 40811853 Free PMC article.
Therapy resistance in AML is mediated by cytoplasmic sequestration of the transcriptional repressor IRF2BP2.
Althoff MJ, Minhajuddin M, Stevens BM, Gillen AE, Gipson S, Patel SB, Shelton IT, Miller R, Vujovic A, Krug A, Young T, Showers WM, Dzieciatkowska M, Stephenson D, Tyagi A, Ellegast JM, Wright T, Stegmaier K, Opferman JT, D'Alessandro A, Smith CA, Jordan CT. Althoff MJ, et al. bioRxiv [Preprint]. 2025 May 24:2025.05.22.655396. doi: 10.1101/2025.05.22.655396. bioRxiv. 2025. PMID: 40475530 Free PMC article. Preprint.
Venetoclax Alone or in Combination With Chemotherapy in Paediatric and Adolescent/Young Adult Patients With Relapsed/Refractory Acute Myeloid Leukaemia.
Karol SE, Khaw SL, Zwaan CM, Baruchel A, Bittencourt H, Cooper TM, Flotho C, Fraser C, Forlenza CJ, Goldsmith KC, Macy ME, Morgenstern DA, O'Brien MM, Petit A, Ziegler DS, Reinhardt D, Opferman JT, Rubnitz JE, Onishi M, Dunshee DR, Dunbar F, Vishwamitra D, Ross JA, Chen X, Unnebrink K, Kammerlander M, Salem AH, Palenski TL, Sunkersett G, Place AE. Karol SE, et al. Pediatr Blood Cancer. 2025 Jul;72(7):e31714. doi: 10.1002/pbc.31714. Epub 2025 Apr 23. Pediatr Blood Cancer. 2025. PMID: 40266036 Clinical Trial.
The BCL-2 protein family: from discovery to drug development.
Croce CM, Vaux D, Strasser A, Opferman JT, Czabotar PE, Fesik SW. Croce CM, et al. Cell Death Differ. 2025 Aug;32(8):1369-1381. doi: 10.1038/s41418-025-01481-z. Epub 2025 Apr 9. Cell Death Differ. 2025. PMID: 40204952 Free PMC article. Review.
84 results