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181 results

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Page 1
Cohort Profile: A European Multidisciplinary Network for the Fight against HIV Drug Resistance (EuResist Network).
Rossetti B, Incardona F, Di Teodoro G, Mommo C, Saladini F, Kaiser R, Sönnerborg A, Lengauer T, Zazzi M; EuResist Network. Rossetti B, et al. Among authors: kaiser r. Trop Med Infect Dis. 2023 Apr 23;8(5):243. doi: 10.3390/tropicalmed8050243. Trop Med Infect Dis. 2023. PMID: 37235291 Free PMC article.
The EuResist cohort was established in 2006 with the purpose of developing a clinical decision-support tool predicting the most effective antiretroviral therapy (ART) for persons living with HIV (PLWH), based on their clinical and virological data. Further to continuous ex …
The EuResist cohort was established in 2006 with the purpose of developing a clinical decision-support tool predicting the most effec …
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation.
Jensen BO, Knops E, Cords L, Lübke N, Salgado M, Busman-Sahay K, Estes JD, Huyveneers LEP, Perdomo-Celis F, Wittner M, Gálvez C, Mummert C, Passaes C, Eberhard JM, Münk C, Hauber I, Hauber J, Heger E, De Clercq J, Vandekerckhove L, Bergmann S, Dunay GA, Klein F, Häussinger D, Fischer JC, Nachtkamp K, Timm J, Kaiser R, Harrer T, Luedde T, Nijhuis M, Sáez-Cirión A, Schulze Zur Wiesch J, Wensing AMJ, Martinez-Picado J, Kobbe G. Jensen BO, et al. Among authors: kaiser r. Nat Med. 2023 Mar;29(3):583-587. doi: 10.1038/s41591-023-02213-x. Epub 2023 Feb 20. Nat Med. 2023. PMID: 36807684 Free PMC article.
Personalized HIV therapy to control drug resistance.
Lengauer T, Pfeifer N, Kaiser R. Lengauer T, et al. Among authors: kaiser r. Drug Discov Today Technol. 2014 Mar;11:57-64. doi: 10.1016/j.ddtec.2014.02.004. Drug Discov Today Technol. 2014. PMID: 24847654 Free article. Review.
Genotypic coreceptor analysis.
Sierra S, Kaiser R, Thielen A, Lengauer T. Sierra S, et al. Among authors: kaiser r. Eur J Med Res. 2007 Oct 15;12(9):453-62. Eur J Med Res. 2007. PMID: 17933727 Review.
SARS-CoV-2 Test-to-Stay in Daycare.
Dewald F, Steger G, Fish I, Torre-Lage I, Hellriegel C, Milz E, Kolb-Bastigkeit A, Heger E, Fries M, Buess M, Marizy N, Michaelis B, Suárez I, Rubio Quintanares GH, Pirkl M, Aigner A, Oberste M, Hellmich M, Wong A, Orduz JC, Fätkenheuer G, Dötsch J, Kossow A, Moench EM, Quade G, Neumann U, Kaiser R, Schranz M, Klein F. Dewald F, et al. Among authors: kaiser r. Pediatrics. 2024 May 1;153(5):e2023064668. doi: 10.1542/peds.2023-064668. Pediatrics. 2024. PMID: 38596855
Time on drug analysis based on real life data.
Schülter E, Kaiser R, Zazzi M, Sönnerborg A, Camacho R, Verheyen J. Schülter E, et al. Among authors: kaiser r. J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19790. doi: 10.7448/IAS.17.4.19790. eCollection 2014. J Int AIDS Soc. 2014. PMID: 25397534 Free PMC article.
MATERIALS AND METHODS: To evaluate the running time of each drug used in HIV-1 treatment, we extracted therapy episodes from the latest release of the EuResist database (www.euresist.org). The evaluation period was from Oct 2006 to Oct 2012. ...RESULTS: At the time …
MATERIALS AND METHODS: To evaluate the running time of each drug used in HIV-1 treatment, we extracted therapy episodes from the latest rele …
Tenofovir resistance and resensitization.
Wolf K, Walter H, Beerenwinkel N, Keulen W, Kaiser R, Hoffmann D, Lengauer T, Selbig J, Vandamme AM, Korn K, Schmidt B. Wolf K, et al. Among authors: kaiser r. Antimicrob Agents Chemother. 2003 Nov;47(11):3478-84. doi: 10.1128/AAC.47.11.3478-3484.2003. Antimicrob Agents Chemother. 2003. PMID: 14576105 Free PMC article.
Viral clones with various combinations of the mutations M41L, K70R, L210W, and T215F or T215Y were analyzed for cross-resistance induced by thymidine analogue mutations (TAMs). The levels of increased resistance induced by single, double, and triple mutations at the …
Viral clones with various combinations of the mutations M41L, K70R, L210W, and T215F or T215Y were analyzed for cross-resistance induced …
Analysis of mutational history of multidrug-resistant genotypes with a mutagenetic tree model.
Pirkl M, Büch J, Devaux C, Böhm M, Sönnerborg A, Incardona F, Abecasis A, Vandamme AM, Zazzi M, Kaiser R, Lengauer T, The EuResist Network Study Group. Pirkl M, et al. Among authors: kaiser r. J Med Virol. 2023 Jan;95(1):e28389. doi: 10.1002/jmv.28389. J Med Virol. 2023. PMID: 36484375
To understand the evolution of multidrug resistance, we analyzed the EuResist database to uncover the accumulation of mutations over time. We hypothesize that the accumulation of resistance mutations is not acquired simultaneously and randomly across viral genotypes but ra …
To understand the evolution of multidrug resistance, we analyzed the EuResist database to uncover the accumulation of mutations over …
Predicting response to antiretroviral treatment by machine learning: the EuResist project.
Zazzi M, Incardona F, Rosen-Zvi M, Prosperi M, Lengauer T, Altmann A, Sonnerborg A, Lavee T, Schülter E, Kaiser R. Zazzi M, et al. Among authors: kaiser r. Intervirology. 2012;55(2):123-7. doi: 10.1159/000332008. Epub 2012 Jan 24. Intervirology. 2012. PMID: 22286881 Review.
Systems of this kind, currently including the Resistance Response Database Initiative and the EuResist engine, must learn from the large data sets of patient histories and can provide an objective and accurate estimate of the virological response to different antiretrovira …
Systems of this kind, currently including the Resistance Response Database Initiative and the EuResist engine, must learn from the la …
Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children.
Dewald F, Suárez I, Johnen R, Grossbach J, Moran-Tovar R, Steger G, Joachim A, Rubio GH, Fries M, Behr F, Kley J, Lingnau A, Kretschmer A, Gude C, Baeza-Flores G, Del Valle DL, Roblero-Hernandez A, Magana-Cerino J, Hernandez AT, Ruiz-Quinones J, Schega K, Linne V, Junker L, Wunsch M, Heger E, Knops E, Di Cristanziano V, Meyer M, Hünseler C, Weber LT, Lüers JC, Quade G, Wisplinghoff H, Tiemann C, Zotz R, Jomaa H, Pranada A, Herzum I, Cullen P, Schmitz FJ, Philipsen P, Kirchner G, Knabbe C, Hellmich M, Buess M, Wolff A, Kossow A, Niessen J, Jeworutzki S, Schräpler JP, Lässig M, Dötsch J, Fätkenheuer G, Kaiser R, Beyer A, Rybniker J, Klein F. Dewald F, et al. Among authors: kaiser r. Nat Commun. 2022 Jun 25;13(1):3640. doi: 10.1038/s41467-022-30664-2. Nat Commun. 2022. PMID: 35752615 Free PMC article.
181 results