khamlichi aa - Search Results

Year	Number of Results
1992	3
1993	3
1994	3
1995	3
1997	1
2000	2
2001	1
2003	1
2004	2
2006	2
2007	3
2009	3
2010	3
2011	2
2014	3
2015	3
2017	1
2018	3
2019	3
2020	3
2021	2
2022	1
2023	2
2024	2
2025	2
2026	1

1

Differential regulation of immunoglobulin class switch recombination by the tumor suppressor p53.

Hanefioui K, Dauba A, Payrault C, Guessous F, Khamlichi AA. Hanefioui K, et al. Among authors: khamlichi aa. Sci Rep. 2026 Apr 25. doi: 10.1038/s41598-026-49435-w. Online ahead of print. Sci Rep. 2026. PMID: 42031945 Free article.

2

The IL7 receptor and the RAG complex are required for the onset of B-cell acute lymphoblastic leukemia.

Dauba A, Näser E, Nouhaud A, Delabesse E, Gerby B, Khamlichi AA. Dauba A, et al. Among authors: khamlichi aa. Blood Adv. 2025 Oct 14;9(19):5010-5014. doi: 10.1182/bloodadvances.2025016313. Blood Adv. 2025. PMID: 40706050 Free PMC article. No abstract available.

3

Modeling the PAX5P80R Mutation Reveals HIF2α Activation as a Common Feature and Therapeutic Target in B-cell Acute Lymphoblastic Leukemia.

Bayet M, Fregona V, Bouttier M, Rouzier C, Bigot J, Jamrog L, Hebrard S, Prade N, Lagarde S, Didier C, Gachet S, Passet M, Largeaud L, Pasquet M, Khamlichi AA, Clappier E, Delabesse E, Broccardo C, Gerby B. Bayet M, et al. Among authors: khamlichi aa. Cancer Res. 2025 Aug 1;85(15):2820-2837. doi: 10.1158/0008-5472.CAN-24-1698. Cancer Res. 2025. PMID: 40354631 Free article.

4

The immunoglobulin heavy chain super enhancer controls class switch recombination in developing B cells.

Dauba A, Näser E, Andrieux D, Cogné M, Denizot Y, Khamlichi AA. Dauba A, et al. Among authors: khamlichi aa. Sci Rep. 2024 Mar 28;14(1):7370. doi: 10.1038/s41598-024-57576-z. Sci Rep. 2024. PMID: 38548819 Free PMC article.

5

Stem cell-like reprogramming is required for leukemia-initiating activity in B-ALL.

Fregona V, Bayet M, Bouttier M, Largeaud L, Hamelle C, Jamrog LA, Prade N, Lagarde S, Hebrard S, Luquet I, Mansat-De Mas V, Nolla M, Pasquet M, Didier C, Khamlichi AA, Broccardo C, Delabesse É, Mancini SJC, Gerby B. Fregona V, et al. Among authors: khamlichi aa. J Exp Med. 2024 Jan 1;221(1):e20230279. doi: 10.1084/jem.20230279. Epub 2023 Nov 6. J Exp Med. 2024. PMID: 37930337 Free PMC article.

6

Attempts to evaluate locus suicide recombination and its potential role in B cell negative selection in the mouse.

Denis-Lagache N, Oblet C, Marchiol T, Baylet A, Têteau O, Dalloul I, Dalloul Z, Zawil L, Dézé O, Cook-Moreau J, Saintamand A, Boutouil H, Khamlichi AA, Carrion C, Péron S, Le Noir S, Laffleur B, Cogné M. Denis-Lagache N, et al. Among authors: khamlichi aa. Front Immunol. 2023 Jun 9;14:1155906. doi: 10.3389/fimmu.2023.1155906. eCollection 2023. Front Immunol. 2023. PMID: 37359540 Free PMC article.

7

Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination.

Oudinet C, Zhang X, Puget N, Kyritsis N, Leduc C, Braikia FZ, Dauba A, Alt FW, Khamlichi AA. Oudinet C, et al. Among authors: khamlichi aa. Front Immunol. 2022 May 16;13:870933. doi: 10.3389/fimmu.2022.870933. eCollection 2022. Front Immunol. 2022. PMID: 35651614 Free PMC article.

8

Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements.

Dauba A, Khamlichi AA. Dauba A, et al. Among authors: khamlichi aa. Front Immunol. 2021 Sep 14;12:738216. doi: 10.3389/fimmu.2021.738216. eCollection 2021. Front Immunol. 2021. PMID: 34594340 Free PMC article. Review.

9

Mechanism and regulation of class switch recombination by IgH transcriptional control elements.

Oudinet C, Braikia FZ, Dauba A, Khamlichi AA. Oudinet C, et al. Among authors: khamlichi aa. Adv Immunol. 2020;147:89-137. doi: 10.1016/bs.ai.2020.06.003. Epub 2020 Jul 25. Adv Immunol. 2020. PMID: 32981636

10

Interleukin 7 regulates switch transcription in developing B cells.

Dauba A, Braikia FZ, Oudinet C, Khamlichi AA. Dauba A, et al. Among authors: khamlichi aa. Cell Mol Immunol. 2021 Mar;18(3):776-778. doi: 10.1038/s41423-020-0430-y. Epub 2020 Apr 16. Cell Mol Immunol. 2021. PMID: 32300210 Free PMC article. No abstract available.

11

Recombination may occur in the absence of transcription in the immunoglobulin heavy chain recombination centre.

Oudinet C, Braikia FZ, Dauba A, Khamlichi AA. Oudinet C, et al. Among authors: khamlichi aa. Nucleic Acids Res. 2020 Apr 17;48(7):3553-3566. doi: 10.1093/nar/gkaa108. Nucleic Acids Res. 2020. PMID: 32086526 Free PMC article.

12

Essential role of the initial activation signal in isotype selection upon deletion of a transcriptionally committed promoter.

Santos JM, Oudinet C, Schöne L, Dauba A, Khamlichi AA. Santos JM, et al. Among authors: khamlichi aa. Sci Rep. 2019 Dec 6;9(1):18543. doi: 10.1038/s41598-019-54929-x. Sci Rep. 2019. PMID: 31811188 Free PMC article.

13

Two modes of cis-activation of switch transcription by the IgH superenhancer.

Santos JM, Braikia FZ, Oudinet C, Dauba A, Khamlichi AA. Santos JM, et al. Among authors: khamlichi aa. Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14708-14713. doi: 10.1073/pnas.1902250116. Epub 2019 Jul 2. Proc Natl Acad Sci U S A. 2019. PMID: 31266889 Free PMC article.

14

Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus.

Oudinet C, Braikia FZ, Dauba A, Santos JM, Khamlichi AA. Oudinet C, et al. Among authors: khamlichi aa. PLoS Genet. 2019 Feb 19;15(2):e1007930. doi: 10.1371/journal.pgen.1007930. eCollection 2019 Feb. PLoS Genet. 2019. PMID: 30779742 Free PMC article.

15

PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.

Jamrog L, Chemin G, Fregona V, Coster L, Pasquet M, Oudinet C, Rouquié N, Prade N, Lagarde S, Cresson C, Hébrard S, Nguyen Huu NS, Bousquet M, Quelen C, Brousset P, Mancini SJC, Delabesse E, Khamlichi AA, Gerby B, Broccardo C. Jamrog L, et al. Among authors: khamlichi aa. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10357-10362. doi: 10.1073/pnas.1721678115. Epub 2018 Sep 26. Proc Natl Acad Sci U S A. 2018. PMID: 30257940 Free PMC article.

16

Parallels between Mammalian Mechanisms of Monoallelic Gene Expression.

Khamlichi AA, Feil R. Khamlichi AA, et al. Trends Genet. 2018 Dec;34(12):954-971. doi: 10.1016/j.tig.2018.08.005. Epub 2018 Sep 11. Trends Genet. 2018. PMID: 30217559 Review.

17

Duplication of a germline promoter downstream of the IgH 3' regulatory region impairs class switch recombination.

Santos JM, Braikia FZ, Oudinet C, Haddad D, Conte C, Dauba A, Khamlichi AA. Santos JM, et al. Among authors: khamlichi aa. Sci Rep. 2018 Jun 15;8(1):9164. doi: 10.1038/s41598-018-27448-4. Sci Rep. 2018. PMID: 29907762 Free PMC article.

18

Inducible CTCF insulator delays the IgH 3' regulatory region-mediated activation of germline promoters and alters class switching.

Braikia FZ, Oudinet C, Haddad D, Oruc Z, Orlando D, Dauba A, Le Bert M, Khamlichi AA. Braikia FZ, et al. Among authors: khamlichi aa. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6092-6097. doi: 10.1073/pnas.1701631114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533409 Free PMC article.

19

Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element.

Braikia FZ, Conte C, Moutahir M, Denizot Y, Cogné M, Khamlichi AA. Braikia FZ, et al. Among authors: khamlichi aa. Mol Cell Biol. 2015 Oct;35(19):3370-80. doi: 10.1128/MCB.00509-15. Epub 2015 Jul 20. Mol Cell Biol. 2015. PMID: 26195822 Free PMC article.

20

Complete cis Exclusion upon Duplication of the Eμ Enhancer at the Immunoglobulin Heavy Chain Locus.

Puget N, Leduc C, Oruc Z, Moutahir M, Le Bert M, Khamlichi AA. Puget N, et al. Among authors: khamlichi aa. Mol Cell Biol. 2015 Jul;35(13):2231-41. doi: 10.1128/MCB.00294-15. Mol Cell Biol. 2015. PMID: 25896912 Free PMC article.

21

Insertion of an imprinted insulator into the IgH locus reveals developmentally regulated, transcription-dependent control of V(D)J recombination.

Puget N, Hirasawa R, Hu NS, Laviolette-Malirat N, Feil R, Khamlichi AA. Puget N, et al. Among authors: khamlichi aa. Mol Cell Biol. 2015 Feb;35(3):529-43. doi: 10.1128/MCB.00235-14. Epub 2014 Nov 17. Mol Cell Biol. 2015. PMID: 25403489 Free PMC article.

22

Quantification of V(D)J recombination by real-time quantitative PCR.

Braikia FZ, Chemin G, Moutahir M, Khamlichi AA. Braikia FZ, et al. Among authors: khamlichi aa. Immunol Lett. 2014 Nov;162(1 Pt A):119-23. doi: 10.1016/j.imlet.2014.08.002. Epub 2014 Aug 12. Immunol Lett. 2014. PMID: 25128366

23

Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells.

Leduc C, Chemin G, Puget N, Sawan C, Moutahir M, Herceg Z, Khamlichi AA. Leduc C, et al. Among authors: khamlichi aa. Cell Cycle. 2014;13(10):1583-9. doi: 10.4161/cc.28560. Epub 2014 Mar 18. Cell Cycle. 2014. PMID: 24675885 Free PMC article.

24

Seeking sense of antisense switch transcripts.

Haddad D, Puget N, Laviolette-Malirat N, Conte C, Khamlichi AA. Haddad D, et al. Among authors: khamlichi aa. Transcription. 2011 Jul;2(4):183-188. doi: 10.4161/trns.2.4.16784. Transcription. 2011. PMID: 21922061 Free PMC article.

25

Sense transcription through the S region is essential for immunoglobulin class switch recombination.

Haddad D, Oruc Z, Puget N, Laviolette-Malirat N, Philippe M, Carrion C, Le Bert M, Khamlichi AA. Haddad D, et al. Among authors: khamlichi aa. EMBO J. 2011 Apr 20;30(8):1608-20. doi: 10.1038/emboj.2011.56. Epub 2011 Mar 4. EMBO J. 2011. PMID: 21378751 Free PMC article.

26

Combined deficiency of MSH2 and Sμ region abolishes class switch recombination.

Leduc C, Haddad D, Laviolette-Malirat N, Nguyen Huu NS, Khamlichi AA. Leduc C, et al. Among authors: khamlichi aa. Eur J Immunol. 2010 Oct;40(10):2925-31. doi: 10.1002/eji.201040605. Eur J Immunol. 2010. PMID: 20812239 Free article.

27

Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.

Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW. Zhang T, et al. Among authors: khamlichi aa. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3040-5. doi: 10.1073/pnas.0915072107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133637 Free PMC article.

28

Replacement of Imu-Cmu intron by NeoR gene alters Imu germ-line expression but has no effect on V(D)J recombination.

Haddad D, Dougier HL, Laviolette N, Puget N, Khamlichi AA. Haddad D, et al. Among authors: khamlichi aa. Mol Immunol. 2010 Feb;47(5):961-71. doi: 10.1016/j.molimm.2009.11.024. Epub 2009 Dec 28. Mol Immunol. 2010. PMID: 20036775

29

S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination.

Wang L, Wuerffel R, Feldman S, Khamlichi AA, Kenter AL. Wang L, et al. Among authors: khamlichi aa. J Exp Med. 2009 Aug 3;206(8):1817-30. doi: 10.1084/jem.20081678. Epub 2009 Jul 13. J Exp Med. 2009. PMID: 19596805 Free PMC article.

30

Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation.

Rajagopal D, Maul RW, Ghosh A, Chakraborty T, Khamlichi AA, Sen R, Gearhart PJ. Rajagopal D, et al. Among authors: khamlichi aa. J Exp Med. 2009 Jun 8;206(6):1237-44. doi: 10.1084/jem.20082514. Epub 2009 May 11. J Exp Med. 2009. PMID: 19433618 Free PMC article.

31

Replacement of Igamma3 germ-line promoter by Igamma1 inhibits class-switch recombination to IgG3.

Oruc Z, Boumédiène A, Le Bert M, Khamlichi AA. Oruc Z, et al. Among authors: khamlichi aa. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20484-9. doi: 10.1073/pnas.0608364104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077389 Free PMC article.

32

Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region.

Huang FT, Yu K, Balter BB, Selsing E, Oruc Z, Khamlichi AA, Hsieh CL, Lieber MR. Huang FT, et al. Among authors: khamlichi aa. Mol Cell Biol. 2007 Aug;27(16):5921-32. doi: 10.1128/MCB.00702-07. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562862 Free PMC article.

33

Internalization and molecular interactions of human CD21 receptor.

Tessier J, Cuvillier A, Glaudet F, Khamlichi AA. Tessier J, et al. Among authors: khamlichi aa. Mol Immunol. 2007 Mar;44(9):2415-25. doi: 10.1016/j.molimm.2006.10.014. Epub 2006 Nov 21. Mol Immunol. 2007. PMID: 17118449

34

Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus.

Samara M, Oruc Z, Dougier HL, Essawi T, Cogné M, Khamlichi AA. Samara M, et al. Among authors: khamlichi aa. Int Immunol. 2006 Apr;18(4):581-9. doi: 10.1093/intimm/dxh400. Epub 2006 Feb 28. Int Immunol. 2006. PMID: 16507599

35

Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.

Glaudet F, Denis V, Cogné M, Khamlichi AA. Glaudet F, et al. Among authors: khamlichi aa. Eur J Immunol. 2004 Jun;34(6):1637-45. doi: 10.1002/eji.200324741. Eur J Immunol. 2004. PMID: 15162433 Free article.

36

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Khamlichi AA, Glaudet F, Oruc Z, Denis V, Le Bert M, Cogné M. Khamlichi AA, et al. Blood. 2004 May 15;103(10):3828-36. doi: 10.1182/blood-2003-10-3470. Epub 2004 Feb 12. Blood. 2004. PMID: 14962903 Free article.

37

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.

Delpy L, Le Bert M, Cogné M, Khamlichi AA. Delpy L, et al. Among authors: khamlichi aa. Eur J Immunol. 2003 Aug;33(8):2108-13. doi: 10.1002/eji.200323969. Eur J Immunol. 2003. PMID: 12884284 Free article.

38

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination.

Pinaud E, Khamlichi AA, Le Morvan C, Drouet M, Nalesso V, Le Bert M, Cogné M. Pinaud E, et al. Among authors: khamlichi aa. Immunity. 2001 Aug;15(2):187-99. doi: 10.1016/s1074-7613(01)00181-9. Immunity. 2001. PMID: 11520455 Free article.

39

Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro.

Bemark M, Khamlichi AA, Davies SL, Neuberger MS. Bemark M, et al. Among authors: khamlichi aa. Curr Biol. 2000 Oct 5;10(19):1213-6. doi: 10.1016/s0960-9822(00)00724-7. Curr Biol. 2000. PMID: 11050391 Free article.

40

The 3' IgH regulatory region: a complex structure in a search for a function.

Khamlichi AA, Pinaud E, Decourt C, Chauveau C, Cogné M. Khamlichi AA, et al. Adv Immunol. 2000;75:317-45. doi: 10.1016/s0065-2776(00)75008-5. Adv Immunol. 2000. PMID: 10879288 Review. No abstract available.

41

Acceleration of intracellular targeting of antigen by the B-cell antigen receptor: importance depends on the nature of the antigen-antibody interaction.

Aluvihare VR, Khamlichi AA, Williams GT, Adorini L, Neuberger MS. Aluvihare VR, et al. Among authors: khamlichi aa. EMBO J. 1997 Jun 16;16(12):3553-62. doi: 10.1093/emboj/16.12.3553. EMBO J. 1997. PMID: 9218797 Free PMC article.

42

Role of light chain variable region in myeloma with light chain deposition disease: evidence from an experimental model.

Khamlichi AA, Rocca A, Touchard G, Aucouturier P, Preud'homme JL, Cogné M. Khamlichi AA, et al. Blood. 1995 Nov 15;86(10):3655-9. Blood. 1995. PMID: 7579330 Free article.

43

Sequences of V kappa L subgroup light chains in Fanconi's syndrome. Light chain V region gene usage restriction and peculiarities in myeloma-associated Fanconi's syndrome.

Rocca A, Khamlichi AA, Touchard G, Mougenot B, Ronco P, Denoroy L, Deret S, Preud'homme JL, Aucouturier P, Cogné M. Rocca A, et al. Among authors: khamlichi aa. J Immunol. 1995 Sep 15;155(6):3245-52. J Immunol. 1995. PMID: 7673737

44

Structure of abnormal heavy chains in human heavy-chain-deposition disease.

Khamlichi AA, Aucouturier P, Preud'homme JL, Cogné M. Khamlichi AA, et al. Eur J Biochem. 1995 Apr 1;229(1):54-60. doi: 10.1111/j.1432-1033.1995.tb20436.x. Eur J Biochem. 1995. PMID: 7744049 Free article.

45

The effect of intron sequences on expression levels of Ig cDNAs.

Khamlichi AA, Rocca A, Cogné M. Khamlichi AA, et al. Gene. 1994 Dec 15;150(2):387-90. doi: 10.1016/0378-1119(94)90458-8. Gene. 1994. PMID: 7821812

46

Monoclonal immunoglobulin deposition disease (Randall type). Relationship with structural abnormalities of immunoglobulin chains.

Preud'homme JL, Aucouturier P, Touchard G, Striker L, Khamlichi AA, Rocca A, Denoroy L, Cogné M. Preud'homme JL, et al. Among authors: khamlichi aa. Kidney Int. 1994 Oct;46(4):965-72. doi: 10.1038/ki.1994.355. Kidney Int. 1994. PMID: 7861722 Free article. Review. No abstract available.

47

Monoclonal immunoglobulin deposition disease: a review of immunoglobulin chain alterations.

Preud'homme JL, Aucouturier P, Touchard G, Khamlichi AA, Rocca A, Denoroy L, Cogné M. Preud'homme JL, et al. Among authors: khamlichi aa. Int J Immunopharmacol. 1994 May-Jun;16(5-6):425-31. doi: 10.1016/0192-0561(94)90032-9. Int J Immunopharmacol. 1994. PMID: 7927989 Review.

48

Brief report: heavy-chain deposition disease.

Aucouturier P, Khamlichi AA, Touchard G, Justrabo E, Cogne M, Chauffert B, Martin F, Preud'homme JL. Aucouturier P, et al. Among authors: khamlichi aa. N Engl J Med. 1993 Nov 4;329(19):1389-93. doi: 10.1056/NEJM199311043291905. N Engl J Med. 1993. PMID: 8413435 Free article. No abstract available.

49

Monoclonal Ig L chain and L chain V domain fragment crystallization in myeloma-associated Fanconi's syndrome.

Aucouturier P, Bauwens M, Khamlichi AA, Denoroy L, Spinelli S, Touchard G, Preud'homme JL, Cogné M. Aucouturier P, et al. Among authors: khamlichi aa. J Immunol. 1993 Apr 15;150(8 Pt 1):3561-8. J Immunol. 1993. PMID: 8468490

50

Primary structure of a variable region of the V kappa I subgroup (ISE) in light chain deposition disease.

Rocca A, Khamlichi AA, Aucouturier P, Noël LH, Denoroy L, Preud'homme JL, Cogné M. Rocca A, et al. Among authors: khamlichi aa. Clin Exp Immunol. 1993 Mar;91(3):506-9. doi: 10.1111/j.1365-2249.1993.tb05932.x. Clin Exp Immunol. 1993. PMID: 7680298 Free PMC article.

51

Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors.

Aucouturier P, Khamlichi AA, Preud'homme JL, Bauwens M, Touchard G, Cogné M. Aucouturier P, et al. Among authors: khamlichi aa. Biochem J. 1992 Jul 1;285 ( Pt 1)(Pt 1):149-52. doi: 10.1042/bj2850149. Biochem J. 1992. PMID: 1379039 Free PMC article.

52

Structurally abnormal immunoglobulins in human immunoproliferative disorders.

Cogné M, Silvain C, Khamlichi AA, Preud'homme JL. Cogné M, et al. Among authors: khamlichi aa. Blood. 1992 May 1;79(9):2181-95. Blood. 1992. PMID: 1571535 Free article. Review. No abstract available.

53

Primary structure of a monoclonal kappa chain in myeloma with light chain deposition disease.

Khamlichi AA, Aucouturier P, Silvain C, Bauwens M, Touchard G, Preud'homme JL, Nau F, Cogné M. Khamlichi AA, et al. Clin Exp Immunol. 1992 Jan;87(1):122-6. doi: 10.1111/j.1365-2249.1992.tb06424.x. Clin Exp Immunol. 1992. PMID: 1733627 Free PMC article.

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