khobta-a OR hobta-a OR hobta-ai - Search Results

Year	Number of Results
1998	1
2001	1
2004	2
2006	2
2007	2
2008	1
2009	1
2010	3
2011	3
2012	2
2013	3
2014	3
2015	1
2016	1
2017	1
2019	1
2020	1
2021	2
2023	2
2024	1
2025	2
2026	0

1

Transcription-Coupled Nucleotide Excision Repair: A Faster Solution or the Only Option?

Khobta A, Sarmini L. Khobta A, et al. Biomolecules. 2025 Jul 16;15(7):1026. doi: 10.3390/biom15071026. Biomolecules. 2025. PMID: 40723898 Free PMC article. Review.

2

Transcription blocking properties and transcription-coupled repair of N²-alkylguanine adducts as a model for aldehyde-induced DNA damage.

Sarmini L, Kitsera N, Meabed M, Khobta A. Sarmini L, et al. J Biol Chem. 2025 May;301(5):108459. doi: 10.1016/j.jbc.2025.108459. Epub 2025 Mar 27. J Biol Chem. 2025. PMID: 40157541 Free PMC article.

3

Targeted nuclear irradiation with a proton microbeam induces oxidative DNA base damage and triggers the recruitment of DNA glycosylases OGG1 and NTH1.

Robeska E, Lalanne K, Vianna F, Sutcu HH, Khobta A, Busso D, Radicella JP, Campalans A, Baldeyron C. Robeska E, et al. DNA Repair (Amst). 2024 Jan;133:103610. doi: 10.1016/j.dnarep.2023.103610. Epub 2023 Dec 5. DNA Repair (Amst). 2024. PMID: 38101146

4

Requirement of transcription-coupled nucleotide excision repair for the removal of a specific type of oxidatively induced DNA damage.

Sarmini L, Meabed M, Emmanouil E, Atsaves G, Robeska E, Karwowski BT, Campalans A, Gimisis T, Khobta A. Sarmini L, et al. Nucleic Acids Res. 2023 Jun 9;51(10):4982-4994. doi: 10.1093/nar/gkad256. Nucleic Acids Res. 2023. PMID: 37026475 Free PMC article.

5

Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-Carboxycytosine.

Müller N, Ponkkonen E, Carell T, Khobta A. Müller N, et al. Int J Mol Sci. 2021 Oct 13;22(20):11025. doi: 10.3390/ijms222011025. Int J Mol Sci. 2021. PMID: 34681690 Free PMC article.

6

Regulation of GC box activity by 8-oxoguanine.

Müller N, Khobta A. Müller N, et al. Redox Biol. 2021 Jul;43:101997. doi: 10.1016/j.redox.2021.101997. Epub 2021 Apr 30. Redox Biol. 2021. PMID: 33965877 Free PMC article.

7

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions.

Rodriguez-Alvarez M, Kim D, Khobta A. Rodriguez-Alvarez M, et al. Biomolecules. 2020 Jun 13;10(6):902. doi: 10.3390/biom10060902. Biomolecules. 2020. PMID: 32545792 Free PMC article.

8

Nucleotide excision repair of abasic DNA lesions.

Kitsera N, Rodriguez-Alvarez M, Emmert S, Carell T, Khobta A. Kitsera N, et al. Nucleic Acids Res. 2019 Sep 19;47(16):8537-8547. doi: 10.1093/nar/gkz558. Nucleic Acids Res. 2019. PMID: 31226203 Free PMC article.

9

Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter.

Kitsera N, Allgayer J, Parsa E, Geier N, Rossa M, Carell T, Khobta A. Kitsera N, et al. Nucleic Acids Res. 2017 Nov 2;45(19):11033-11042. doi: 10.1093/nar/gkx718. Nucleic Acids Res. 2017. PMID: 28977475 Free PMC article.

10

Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine.

Allgayer J, Kitsera N, Bartelt S, Epe B, Khobta A. Allgayer J, et al. Nucleic Acids Res. 2016 Sep 6;44(15):7267-80. doi: 10.1093/nar/gkw473. Epub 2016 May 24. Nucleic Acids Res. 2016. PMID: 27220469 Free PMC article.

11

New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes.

Krieg B, Hirsch M, Scholz E, Nuhn L, Tabujew I, Bauer H, Decker S, Khobta A, Schmidt M, Tremel W, Zentel R, Peneva K, Koynov K, Mason AJ, Helm M. Krieg B, et al. Pharm Res. 2015 Jun;32(6):1957-74. doi: 10.1007/s11095-014-1589-7. Epub 2014 Dec 9. Pharm Res. 2015. PMID: 25488263

12

Excision of uracil from transcribed DNA negatively affects gene expression.

Lühnsdorf B, Epe B, Khobta A. Lühnsdorf B, et al. J Biol Chem. 2014 Aug 8;289(32):22008-18. doi: 10.1074/jbc.M113.521807. Epub 2014 Jun 20. J Biol Chem. 2014. PMID: 24951587 Free PMC article.

13

Cockayne syndrome: varied requirement of transcription-coupled nucleotide excision repair for the removal of three structurally different adducts from transcribed DNA.

Kitsera N, Gasteiger K, Lühnsdorf B, Allgayer J, Epe B, Carell T, Khobta A. Kitsera N, et al. PLoS One. 2014 Apr 8;9(4):e94405. doi: 10.1371/journal.pone.0094405. eCollection 2014. PLoS One. 2014. PMID: 24713864 Free PMC article.

14

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence.

Allgayer J, Kitsera N, von der Lippen C, Epe B, Khobta A. Allgayer J, et al. Nucleic Acids Res. 2013 Oct;41(18):8559-71. doi: 10.1093/nar/gkt620. Epub 2013 Jul 17. Nucleic Acids Res. 2013. PMID: 23863843 Free PMC article.

15

Influences of histone deacetylase inhibitors and resveratrol on DNA repair and chromatin compaction.

Keuser B, Khobta A, Gallé K, Anderhub S, Schulz I, Pauly K, Epe B. Keuser B, et al. Mutagenesis. 2013 Sep;28(5):569-76. doi: 10.1093/mutage/get034. Epub 2013 Jun 29. Mutagenesis. 2013. PMID: 23814181

16

Repair of oxidatively generated DNA damage in Cockayne syndrome.

Khobta A, Epe B. Khobta A, et al. Mech Ageing Dev. 2013 May-Jun;134(5-6):253-60. doi: 10.1016/j.mad.2013.03.001. Epub 2013 Mar 18. Mech Ageing Dev. 2013. PMID: 23518175 Review.

17

Interactions between DNA damage, repair, and transcription.

Khobta A, Epe B. Khobta A, et al. Mutat Res. 2012 Aug 1;736(1-2):5-14. doi: 10.1016/j.mrfmmm.2011.07.014. Epub 2011 Aug 12. Mutat Res. 2012. PMID: 21907218 Review.

18

Generation of reporter plasmids containing defined base modifications in the DNA strand of choice.

Lühnsdorf B, Kitsera N, Warken D, Lingg T, Epe B, Khobta A. Lühnsdorf B, et al. Anal Biochem. 2012 Jun 1;425(1):47-53. doi: 10.1016/j.ab.2012.03.001. Epub 2012 Mar 8. Anal Biochem. 2012. PMID: 22406247

19

8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1.

Kitsera N, Stathis D, Lühnsdorf B, Müller H, Carell T, Epe B, Khobta A. Kitsera N, et al. Nucleic Acids Res. 2011 Aug;39(14):5926-34. doi: 10.1093/nar/gkr163. Epub 2011 Mar 25. Nucleic Acids Res. 2011. PMID: 21441539 Free PMC article.

20

Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol.

Fusser M, Nesse GJ, Khobta A, Xia N, Li H, Klungland A, Epe B. Fusser M, et al. Carcinogenesis. 2011 Jan;32(1):80-5. doi: 10.1093/carcin/bgq196. Epub 2010 Nov 9. Carcinogenesis. 2011. PMID: 21062970

21

Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand.

Khobta A, Lingg T, Schulz I, Warken D, Kitsera N, Epe B. Khobta A, et al. DNA Repair (Amst). 2010 Sep 4;9(9):985-93. doi: 10.1016/j.dnarep.2010.06.011. Epub 2010 Jul 31. DNA Repair (Amst). 2010. PMID: 20674513

22

Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region.

Khobta A, Anderhub S, Kitsera N, Epe B. Khobta A, et al. Nucleic Acids Res. 2010 Jul;38(13):4285-95. doi: 10.1093/nar/gkq170. Epub 2010 Mar 24. Nucleic Acids Res. 2010. PMID: 20338881 Free PMC article.

23

8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein.

Khobta A, Kitsera N, Speckmann B, Epe B. Khobta A, et al. DNA Repair (Amst). 2009 Mar 1;8(3):309-17. doi: 10.1016/j.dnarep.2008.11.006. Epub 2008 Dec 23. DNA Repair (Amst). 2009. PMID: 19061977

24

Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure.

Kitsera N, Khobta A, Epe B. Kitsera N, et al. Biotechniques. 2007 Aug;43(2):222-7. doi: 10.2144/000112479. Biotechniques. 2007. PMID: 17824390 Free article.

25

Generation and characterization of tTS-H4: a novel transcriptional repressor that is compatible with the reverse tetracycline-controlled TET-ON system.

Bockamp E, Christel C, Hameyer D, Khobta A, Maringer M, Reis M, Heck R, Cabezas-Wallscheid N, Epe B, Oesch-Bartlomowicz B, Kaina B, Schmitt S, Eshkind L. Bockamp E, et al. J Gene Med. 2007 Apr;9(4):308-18. doi: 10.1002/jgm.1012. J Gene Med. 2007. PMID: 17330923

26

G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent.

Tonelli R, Sartini R, Fronza R, Freccero F, Franzoni M, Dongiovanni D, Ballarini M, Ferrari S, D'Apolito M, Di Cola G, Capranico G, Khobta A, Campanini R, Paolucci P, Minucci S, Pession A. Tonelli R, et al. Leukemia. 2006 Jul;20(7):1307-10. doi: 10.1038/sj.leu.2404221. Epub 2006 Apr 13. Leukemia. 2006. PMID: 16617320 No abstract available.

27

Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells.

Khobta A, Ferri F, Lotito L, Montecucco A, Rossi R, Capranico G. Khobta A, et al. J Mol Biol. 2006 Mar 17;357(1):127-38. doi: 10.1016/j.jmb.2005.12.069. Epub 2006 Jan 6. J Mol Biol. 2006. PMID: 16427078

28

Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL gene.

Khobta A, Carlo-Stella C, Capranico G. Khobta A, et al. Cancer Res. 2004 Apr 15;64(8):2656-62. doi: 10.1158/0008-5472.can-03-1126. Cancer Res. 2004. PMID: 15087374

29

Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins.

Alessandri M, Beretta GL, Ferretti E, Mancia A, Khobta A, Capranico G. Alessandri M, et al. J Mol Biol. 2004 Mar 19;337(2):295-305. doi: 10.1016/j.jmb.2004.01.032. J Mol Biol. 2004. PMID: 15003448

30

Epidermoid carcinoma-derived antimicrobial peptide (ECAP) inhibits phosphorylation by protein kinases in vitro.

Hobta A, Lisovskiy I, Mikhalap S, Kolybo D, Romanyuk S, Soldatkina M, Markeyeva N, Garmanchouk L, Sidorenko SP, Pogrebnoy PV. Hobta A, et al. Cell Biochem Funct. 2001 Dec;19(4):291-8. doi: 10.1002/cbf.929. Cell Biochem Funct. 2001. PMID: 11746212

31

A protein kinase inhibitor from A431 subline overexpressing TGF alpha possesses antimicrobial activity.

Pogrebnoy PV, Hobta AI, Soldatkina MA, Garmanchouk LV, Markeeva NV, Eremenko T. Pogrebnoy PV, et al. New Microbiol. 1998 Jul;21(3):269-73. New Microbiol. 1998. PMID: 9699208

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